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Volume 34, 12 Issues, 2024

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Important Announcement for Authors

"A companion journal of JCPSP (the official journal of CPSP) has been launched by the name of JCPSP Case Reports. Submission of Case Reports is now open."
Please visit https://jcpspcr.pk/.

Latest Articles
Volume 34 | Issue 5 | May 2024
Air Pollution: Challenges to Human Health in Pakistan

By Mohammad Perwaiz Iqbal


Effect of Intravenous Dexmedetomidine Before Extubation on Emergence Delirium after Nasal Surgeries

By Anwar ul Huda, Mohammad Yasir, Mohammad Zulqarnain Mughal, Asim Arif

ABSTRACT Objective: To investigate the role of single dose of dexmedetomidine (0.5 mcg/kg) in reducing the incidence and severity of postoperative emergence delirium (EmD). Study Design: A randomised controlled trial. Place and Duration of the Study: Department of Anaesthesia, Security Forces Hospit...

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Topical Tacrolimus Ointment Alone versus in Combination with Microneedling for Refractory Stable Vitiligo

By Afshan Kiran, Seemab Khan, Najia Ahmed, Maira Ali

ABSTRACT Objective: To assess the efficacy of microneedling in combination with topical tacrolimus ointment 0.1% versus topical tacrolimus ointment 0.1% for treatment of refractory stable vitiligo. Study Design: Comparative cross-sectional study. Place and Duration of the Study: Department of Dermat...

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Isotretinoin’s Effect on Fasting Lipid Profile in Acne Patients

By Madiha Sajid, Sadaf Ahmed Asim, Tayyaba Iqbal, Sadia Bhatti, Ayesha Zahir, Sania Imtiaz

ABSTRACT Objective: To determine the isotretinoin’s effect on fasting lipid profile in patients with acne. Study Design: Observational study. Place and Duration of the Study: Outpatient Department of Dermatology, Dow International Medical College, Dow University of Health Sciences, Karachi, Pa...

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Effect of Intense Pulsed Light Versus Intradermal Tranexamic Acid for the Management of Melasma

By Sadaf Ahmed Asim, Tayyaba Iqbal, Madiha Sajid, Sadia Bhatti

ABSTRACT Objective: To compare the effectiveness of intense pulsed light (IPL) and intradermal tranexamic acid (TXA) in treating melasma. Study Design: A cross-sectional analytical study. Place and Duration of the Study: Department of Dermatology, Dow International Medical College, Dow University H...

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Specific Knockout of Notch-1 in Macrophages Modulate the Progression of Hepatic Insulin Resistance in HFD Fed Mice via Regulating IRE1α-XBP1 Signals

By Weiling Zhou, Shuguang Ren, Yonggang Lu, Yuan Wang, Lei Feng, Qian Gao

ABSTRACT Objective: To develop an intervention based on Notch-1 signalling pathway blockade by investigating the potential application of the neurogenic locus notch homologue protein 1(Notch-1) signalling pathway as a key regulator of chronic inflammation and adipogenesis in the treatment of hepatic...

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Relationship Between Prepatellar Fat Thickness and Bone Mineral Density

By Hatice Agir, Ozlem Orhan

ABSTRACT Objective: To evaluate the relationship between bone mineral density (BMD) by measuring the prepatellar fat thickness with knee radiography and to gain a measurement method that has not been done before in the literature. Study Design: Cross-sectional descriptive study. Place and Duration ...

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Frequency and Aberrant CD Marker Profile of Acute Leukaemias

By Muhammad Zain Arshad, Muhammad Aftab Hassan, Maryam Bibi, Muhammad Hussain, Mustajab Alam, Muhammad Omair Riaz

ABSTRACT Objective: To determine the frequency of different types of acute leukaemia and their subtypes along with associated aberrant CD markers. Study Design: Descriptive study. Place and Duration of the Study: Department of Immunology Armed Forces Institute of Pathology, National University ...

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Predictors of Nucleos(t)ide Analogues Discontinuation Relapse: Hepatitis B Virus RNA versus Hepatitis B Surface Antigen

By Shuo Wu, Tao Li, Feng Liu, Dedong Yin, Lixin Zhang, Lei Wang

ABSTRACT Objective: To compare the predictive value of hepatitis B virus (HBV) RNA and HBsAg quantification upon discontinuation of nucleos(t)ide analogues (NAs) therapy for clinical and virological relapse in chronic hepatitis B (CHB). Study Design: Observational study. Place and Duration of the St...

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Comparison of the Outcomes of Anterior Cervical Discectomy and Fusion and Cervical Disc Replacement for Cervical Disc Disease

By Alper Tabanli, Emrah Akcay, Hakan Yilmaz, Cafer Ak, Onur Bologur, Engin Kayikci

ABSTRACT Objective: To compare the radiological outcome and development of heterotopic ossification (HO) following single-segment anterior cervical discectomy and fusion (ACDF) and cervical disc replacement (CDR) for cervical disc herniation and evaluate their impact on surgical success. Study Desig...

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Use of the Systemic Immune-Inflammation Index to Predict Treatment Efficacy in Patients with Bladder Pain Syndrome

By Mehmet Fatih Sahin, Esad Eseoglu, Murat Akgul, Arzu Malak, Cagri Dogan, Cenk Murat Yazici

ABSTRACT Objective: To determine the relationship between bladder pain syndrome (BPS) and systemic inflammatory index (SII) and to examine the impact of treatment protocols on it. Study Design: Observational Study. Place and Duration of the Study: Department of Urology, Tekirdag Namik Kemal Universi...

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Selenium Supplementation and Gestational Diabetes: A Randomised Controlled Trial

By Ece Yigit, Ilknur Sayar

ABSTRACT Objective: To assess the effects of selenium supplementation on blood glucose levels in women with gestational diabetes mellitus (GDM). Study Design: Randomised controlled trial. Place and Duration of the Study: Department of Internal Medicine, Istanbul Medipol University, Faculty of Medic...

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Impact of Geko Neuromuscular Stimulator on Preoperative Preparation in Ankle Fractures

By Xue Zhao, Jianzhong Zhang, Yujing Li, Zhihong Nie, Wei Wang, Yan Dong

ABSTRACT Objective: To explore the impact of the Geko neuromuscular stimulator on preoperative preparation in patients with ankle fractures. Study Design: Quasi-experiment study. Place and Duration of the Study: Department of Foot and Ankle Surgery and Department of Orthopaedics, Beijing Tongren H...

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Treatment Related Acute Toxicities Between Treatment with 3D-CRT and IMRT in Localised Prostate Cancer

By Shoaib Hanif, Asif Husain Osmani, Jawaid Mallick

ABSTRACT Objective: To compare the acute toxicities of two radiation treatment techniques, intensity modulated radiation therapy (IMRT), and 3-dimensional conformal radiation therapy (3D-CRT) in localised prostate adenocarcinoma. Study Design: Descriptive study. Place and Duration of the Study...

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STONE Score: A Predictor for Need of Blood Transfusion in Percutaneous Nephrolithotomy

By Aniqa Saeed, Wajahat Aziz, Alizah Pervaiz Hashmi, Hammad Ather

ABSTRACT Objective: To determine if the STONE score is a predictor of blood transfusion and if patient-related factors, i.e., the presence of comorbidities such as urinary tract infection and obesity, can predict blood transfusion post-percutaneous nephrolithotomy. Study Design: A cross-section...


Single Versus Double Tunnel Fixation in Medial Patellofemoral Ligament Reconstruction: A Meta-Analysis

By Hongwei Zhan, Jin Jiang, Zhi Yi, Jinwen He, Meng Wu, Yayi Xia

ABSTRACT The purpose of this meta-analysis was to conduct a comparative analysis of clinical scores and complication rates among patients experiencing recurrent patellar dislocation who underwent medial patellofemoral ligament (MPFL) reconstruction using both single and double tunnel techniques. A c...

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The Revival of Essay-Type Questions in Medical Education: Harnessing Artificial Intelligence and Machine Learning

By Muhammad Shahid Shamim, Syed Jaffar Abbas Zaidi, Abdur Rehman

ABSTRACT Objective: To analyse and compare the assessment and grading of human-written and machine-written formative essays. Study Design: Quasi-experimental, qualitative cross-sectional study. Place and Duration of the Study: Department of Science of Dental Materials, Hamdard College of Medicine &a...

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2D/4D Finger Length Ratio in the Screening of Developmental Dysplasia of the Hip

By Ismail Hakki Korucu, Numan Duman

ABSTRACT Objective: To investigate whether there is a relationship between the 2nd finger and 4th finger length measurement ratios and developmental dysplasia of the Hip (DDH). Study Design: Cross-sectional observational study. Place and Duration of the Study: Department of Orthopaedics and Tra...

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Outcome and Factors Related to Isolated Liver Metastasis due to Breast Cancer

By Ebru Sen, Tolga Canbak, Ozgur Bostanci, Muharrem Battal

ABSTRACT Objective: To determine the associated risk factors for isolated liver metastasis in breast cancer patients and to detect the prognostic factors related to survival. Study Design: Analytical study. Place and Duration of the Study: Department of General Surgery, The University of Health Scie...

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Association of Preoperative Subchondral Bone Marrow Oedema with Outcomes after Lateral Unicompartmental Knee Arthroplasty

By Qilong Jiang, Xinwen Bai, Yu Deng, Huan Xia

ABSTRACT Objective: To determine whether the presence of preoperative subchondral bone marrow oedema (SBME) is associated with inferior outcomes after lateral unicompartmental knee arthroplasty (LUKA). Study Design: Descriptive study. Place and Duration of the Study: Department of Orthopaedic Surger...

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Task Oriented Assessment of Clinical Skills (TOACS): A Modified Form of OSCE

By Sirajul Haque Shaikh, Shabnam Iqbal Memon, Sahar Zubair Abbasi

ABSTRACT College of Physicians and Surgeons, Pakistan (CPSP) is a premier postgraduate medical institution of the country. It introduced Objective Structured Clinical Examination (OSCE) in the 1990s, and later came up with its modified form known as Task Oriented Assessment of Clinical Skills (TOACS...


Association Between Triglyceride-Glucose Index and Homeostasis Model Assessment for Insulin Resistance with Estimated Glucose Disposal Rate

By Sikandar Hayat Khan, Ayesha Hafeez, Yasser Khan, Usama Bin Khalid, Shahrukh Shah, Ahsan Ahmad Ghauri

ABSTRACT This cross-sectional study was aimed to compare insulin resistance, Triglyceride- Glucose (TyG) index, fatty liver index (FLI) and hepatic steatosis index (HSI), glycaemic and lipids among groups/quartiles based upon estimated Glucose Disposal Rate (eGDR) from August 2022 to December 2022 a...


Gender Difference of Burnout in Physicians Working in Tertiary Care Hospital: A Cross-Sectional Study

By Mariam Khan Qamar, Babar Tasneem Shaikh, Ramesh Kumar, Armaghana Khan Qamar

ABSTRACT Burnout and emotional exhaustion are becoming common among health workers in the busy teaching hospitals due to increased workload and the dearth of human resource. This study aimed to determine the causes of burnout among doctors and across gender differences. This was a descriptive cross-...


How Can We Ensure that the Perioperative Management of Patients Undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) is Safe?

By Faraz Mansoor, Mahnoor Durrani


Vestibular Rehabilitation: Intelligent or Traditional?

By Dandan Zhao, Dandan Zhao, Hao Feng


Addressing the Data Gap: The Importance of National Cancer Registries

By Amna Khan


In Response to “Acute Oral Mucositis During Hypo-Fractionated Radiation in Squamous Cell Carcinoma of Oral Cavity”

By Muhammad Shahid Iqbal, Josef Kovarik, Charles Kelly


Comment on Rehman et al. “Short-Term Outcomes of Elective Abdominal Aortic Aneurysm Repair”

By Ahsan Zil-e-Ali