Epub Ahead of Print

A case with neonatal onset Type 2 Neuronal Ceroid Lipofuscinosis: A novel mutation

By Ozgun Uygur, Mehmet Yekta Oncel, Pinar Gencpinar, Burcu Ozturk Hismi, Merve Saka Guvenc, Nihal Olgac Dundar,

Neuronal Ceroid Lipofuscinosis (NCL) is a lysosomal storage disorder that causes progressive neurodegenerative disease as a result of storage in ne...

MULTIMODAL IMAGING OF OPTIC NERVE DRUSEN IN A HYPEROPIC CHILD

By Sehnaz Ozcaliskan, Ozgur Artunay,

Optic nerve drusen (OND) are abnormal calcified acellular deposits located within the prelaminar portion of the optic nerve. They are usually asymp...

Late diagnosis of Paracetamol poisoning is always lethal in young adult

By Sehrish Naz, Safia Fatima, Muhammad Aamir,

Acetaminophen has a remarkable safety profile when prescribed in proper therapeutic doses but hepatotoxicity can occur when misused or after an ove...

Radiologic findings of scapular langerhans cell histiocytosis successfully treated with CT guided corticosteroid injection

By Cennet Sahin, Burcin Agridag Agridag Ucpinar, Yunus Oc, Fevziye Kabukcuoglu,

Although Langerhans Cell Histiocytosis (LCH) may arise from any bone, flat bones (skull, ribs, scapula, clavicle, and mandible) are more commonly i...

Control of Refractory Hypercalcemia with Denosumab in a case of Metastatic Parathyroid Carcinoma

By Murat Çalapkulu, Ozen Oz Gul, Soner Cander, Canan Ersoy, Erdinc Erturk, Muhammed Fatih Sagiroglu, Ozlem Saraydaroglu,

Parathyroid carcinoma is a rare cause of hyperparathyroidism and leads to severe hypercalcemia. The etiology is not fully known. Parathyroid cancer...

Comparison the effects of ultrasound-guided erector spinae plane block and wound infiltration on perioperative opioid consumption, intraoperative hormonal stress response and postoperative pain in thoracotomy

By Qiang Wang, Guohua Zhang, Shijing Wei, Zhibin He, Li Sun, Hui Zheng,

Objective: To compare the effects of preoperative ultrasound-guided erector spinae plane block (ESPB) and preoperative wound infil...

Unilateral Optic Neuropathy Due To a Sphenoid Mucocoele

By Sana Nadeem, Amir Akbar, Aasma Nudrat Zafar,

Isolated sphenoid sinus mucocoeles are rare, benign lesions usually discovered incidentally. They can present with headache, diplopia, visual loss ...

Snail Fever of The Bladder In A Non-Endemic Area – A Case Report From Pakistan

By Zehra Kazmi, Muhammad Areeb Ashfaq, Daniya Umer, Romana Idress, Muhammad Hammad Ather,

Schistosomiasis is rarely seen in Pakistan and is generally not very high on the list of differential diagnoses. However, it is an important cause ...

Educational Approach of Blended Learning in Teaching Benign Paroxysmal Positional Vertigo in the Emergency Department

By Khalid Bashir, Stephen Thomas,

Objective: To investigate the efficacy of blended learning (BL) in emergency medical resident education related to the diagnosis a...

What can be done for Large and Multiple Choledochal Stones?

By Ufuk Arslan, Haci Murat Cayci, Ali Tardu, Umut Eren Erdogdu,

Endoscopic retrograde cholangiopancreatography may fail to extract large and multiple choledochal stones in a single session, necessitating a repea...

Myxoid Liposarcoma with Cartilagenous Differentiation – A Case Report

By Hina Tariq, Tariq Sarfraz, Iqra Saeed,

Myxoid liposarcoma (MLPS) is an adipocytic tumour and second commonest among the types of liposarcoma. It exhibits a wide histological spectrum. It...

Anaesthesia Management of a Patient with Glucose-6-Phosphate Dehydrogenase Deficiency Undergoing Total Thyroidectomy: A Case Report

By Muhammad Yasir, Anwar Ul Huda,

We present anaesthesia management of a patient having Glucose-6-phosphate dehydrogenase (G6PD) deficiency who underwent thyroidectomy. The main con...

Zero ischemia partial nephrectomy in pregnancy: A case report.

By Omer Vefik Ozozan,

Renal cell carcinoma (RCC) represents 2-3% of all cancers. Although it is rare, RCC is the most common urologic malignancy reported in pregnancy. M...

SCAR ECTOPIC PREGANACY

By Dr Asma Kashif,

Cesarean scar ectopic is a rare kind of ectopic pregnancy. It is defined as low implantation of blastocyst on the scar in the uterus. The incidence...

Pancreaticogastrostomy: A safe option in pancreaticoduodenectomy for pancreatic head and periampullary neoplasms.

By Muhammad Asif Noor, Faisal Hanif, Osama Shakeel, Hassaan Bari,

Objective: To determine the safety of pancreaticogastrostomy in pancreaticoduodenectomy in patients with periampullary and pancrea...

A Mature Cystic Teratoma of the Urinary Bladder

By Safdar Shah, Wajid Ali, Imran Ansari, Shams -ul -islam,

We report a case of a mature cystic teratoma of urinary bladder in a 17-year female, which is extremely rare. The patient presented with pain in supra...

Unilateral Synchronous Multiple Kidney Tumors Managed by Laparoscopic Partial Nephrectomy: Five-year Follow-up

By Mehmet Necmettin Mercimek, Latif Mustafa Ozbek, Ender Ozden,

Unilateral synchronous multifocal renal tumors are rare. Due to the limited data in the literature and challenges in the technique, there is still dou...

Bladder-sparing Approach in a Woman with Muscle-invasive Primary Bladder Melanoma

By Mehmet Necmettin Mercimek, Ender Ozden,

Primary bladder melanoma (PBM) is an extremely rare tumor. Herein, we present a 39-year female evaluated for a history of dysuria and hematuria for on...

Robot-assisted Laparoscopic Nephroureterectomy for a Nephrogenic Adenoma of Ureter

By Keiran David Clement, Catherine Thompson, Omar M. Aboumarzouk,

Nephrogenic adenoma is a rare and benign tumour of the urinary tract thought to be caused by metaplastic change of native urothelial tissue. The major...

Benign Broncho-esophageal Fistula Presenting as Unresolved Pneumonia

By Waseem M. Hajjar, Lamyaa A. Althawadi, Nada A. Bin Semaih, Adnan W. Hajj, Sami A. Al-nassar,

Benign acquired broncho-esophageal fistula (BEF) in adults is a very rare entity and has not been reported properly in the literature, compared to mal...

A Case of Immunoglobulin (Ig) G4-related Sclerosing Periaortitis Mimicking Mediastinal Malignant Tumor

By Fuat Erel, Mustafa Kuzucuoglu, Nurhan Sarioglu, Eren Altun,

Sclerosing mediastinitis was first described by Oulmont in 1855. The aggressive fibro-inflammatory process that occurs in the mediastinum is the end r...

Laparoscopic Resection of Isolated Retroperitoneal Gastric Duplication Cyst in an Infant

By Vipul Gupta, Usman Javaid, Ghadir Jaber, Diary Mohd, Mamoun Almarzouqi,

We, herein report a rare case of retroperitoneal gastric duplication cyst in a 5-month female infant presenting with antenatal diagnosis of right rena...

Recurrent, Large, Extraskeletal Osteosarcoma at the Back

By Muhammad Danish Muneeb, Mirza Agha Naushad Baig,

Extraskeletal osteosarcoma is a rarely identified variety of sarcomas throughout the world, which is still a dilemma for the surgeons\' community with...

Surgical Treatment of Ankylosing Spondylitis with Andersson Lesion

By Fengguang Yang, Liang Yang, Enhui Ren, Yong Yang, Jing Wang, Xuewen Kang,

Ankylosing spondylitis (AS) with an Andersson lesion may cause kyphosis. As the disease progresses, kyphosis gradually worsens. When conservative trea...

Pelvic Angiosarcoma Around Total Hip Prosthesis

By Alberto Sánchez, Alberto Pérez García, Enrique Salmerón González,

Angiosarcomas constitute less than 1% of primary bone malignancies. Their association with prosthetic material has been described, while their etiolog...

Surgically-assisted Rapid Maxillary Expansion under Local Anesthesia

By Cansu Gul Koca, Ihsan Sami Guvenc,

Developmental, traumatic and congenital factors, among many others, may lead to transverse maxillary deficiency (TMD). TMD can be corrected by orthod...

A Patient of Advanced NSCLC with a New EGFR Exon 19 Insertion Mutation and its Response to EGFR-TKIs

By Ning Zhu, Caixia Dong, Shanshan Weng, Ying Yuan,

Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are the standard therapy for patients with advanced non-small-cell lung cancer...

The First Described Case of Bizarre Leiomyoma of the Portal Vein

By Murat Ferhat Ferhatoglu,

Vascular leiomyomas with bizarre nuclei are rare. Differentiation of these tumors from malignant lesions is essential to avoid unnecessary dissection ...

Solitary Endobronchial Papilloma: A Rare Entity

By Muhammad Soban Arif Maan, Muhammad Waleed, Amir Humza Sohail, Asna Sulaiman, Javaid Ahmed Khan,

Solitary papillomas of the lower airways are uncommon clinical entities that present a diagnostic challenge because they are not usually considered am...

Deep-seated Hibernoma of Thigh: A Rare Benign Adipocytic Tumor

By Muhammad Omar Afzal, Ata Ul Haq, Sobia Mazhar, Moazzam Nazeer Tarar,

Hibernoma is a rare benign soft tissue adipocytic tumor. Mostly found in adults, it is usually located in the limbs, and is deepseated or intramuscula...

High Grade Encapsulated Papillary Carcinoma of Breast in a Young Female

By Madiha Bilal Qureshi, Naila Kayani,

Encapsulated papillary carcinoma (EPC) is a special type of papillary breast lesion known to be of low and intermediate grade. But recent data suggest...

Tumour-to-tumour Metastasis: Cutaneous Melanoma Metastasizing to Leiomyoma Uteri

By Jelena Amidzic, Nenad Solajic, Aleksandra Fejsa Levakov, Matilda Djolai, Nada Vuckovic,

The incidence of melanoma is increasing worldwide. It is known that melanoma frequently progresses to metastatic disease. The aim of this report is t...

Sigmoid Sinus Thrombosis with Cerebellar Tuberculous Abscess: A Rare Case of Chronic Headache with Vision Loss

By Ahmed Tanjimul Islam, Kafil Uddin, Ahmed Ali, Pijush Kumar Kundu, Munzur Alahi, Mukul Kumar Sarkar,

Cerebral venous sinus thrombosis (CVST) is a rare form of brain stroke which is often misdiagnosed. We present a case of CVST due to cerebellar tuberc...

A Case of Polyautoimmunity: Celiac Hepatitis, Grave\'s Disease and Autoimmune Hemolytic Anemia

By Nazish Butt, Muhammad Ali Khan, Zain Abid, Farhan Haleem,

Celiac disease (CD) is an autoimmune disorder with high incidence of multi organ involvement; especially, gastrointestinal manifestations and an incre...

Acute Viral Hepatitis: Simultaneous Infection from Hepatitis A, B and E Viruses

By Nazish Butt, M. Ali Khan, Farhan Haleem,

Acute viral hepatitis is a significant health problem in the developing world. Usually, the disease runs a benign course with complete resolution o...

Kallmann Syndrome with Syndactyly

By Farid Kassidi, Majdouline Boujoual, Moulay El Mehdi El Hassani,

Kallmann syndrome is a rare genetic disorder marked by hypogonadotropic hypogonadism (HH) and anosmia, affecting 1 in 50,000 females. It is due to a d...

Improvement of Esophageal Anastomotic Leak by Vacuum-assisted Closure in Three Cases with Gastric Cancer

By Seracettin Egin, Semih Hot,

This case report presents three consecutive patients who developed esophageal anastomotic leak after gastric cancer surgery and were treated by the tw...

Strangulated Intrapericardial Diaphragmatic Hernia after Hybrid Maze Procedure

By Muhammad Fahim, Tim Campbell-smith,

Convergent hybrid maze procedure is very safe and effective surgical modality for the treatment of refractory atrial fibrillation. It carries very lit...

Topical Sevoflurane: An Alternative Treatment for Pressure Ulcers

By Isin Gencay,

Pressure ulcers are a common problem in intensive care unit (ICU). Recently, topical sevoflurane has been used especially for treatment of venous ulc...

Self-expanding Metallic Stent Placement in Malignant Terminal Ileal Stricture

By Kailash Raj Makhejani, Muhammad Mansoor Ul Haq, Jawaid Iqbal, Naila Zahid,

Malignancies of gastro-intestinal tract cause stricture formation that leads to intestinal obstruction. In such cases, either surgery or placement of ...

Neurolymphomatosis of the Sciatic and Tibial Nerves

By Muhammad Talha Yaseen, Pir Abdul Ahad Aziz, Kashif Siddique, Taimoor Ali Tariq,

Neurolymphomatosis (NL) is an uncommon clinical condition, characterised by lymphomatous infiltration of the central and/or peripheral nervous system....

Partial Malrotation of Bowel Loops in an Adolescent with Left Hypochondrial Pain

By Kanwal Laique, Syed Mubarak Ali,

In the embroyological development, any deviation from physiological midgutrotation results in intestinal malrotation, which may further cause midgutvo...

A Single Coronary Artery with an Absent Right Coronary and a Superdominant Left Circumflex Giving off a Branch Supplying the Right Coronary Artery Territory

By Imran Iftikhar, Adeel Ur Rehman, Hamid Sharif Khan,

An absent right coronary artery (RCA) with single left coronary artery (LCA) originating from left aortic sinus with a superdominant left circumflex (...

Accessory Cardiac Conduction Pathway with an Unusual Presentation

By Ikram Ahmed Rana, Wajeeha Afzal,

Pre-excitation syndrome (PES) is a congenital abnormality in which there is conduction through accessory pathway in addition to atrioventricular (AV) ...

Anaesthetic Management of Cerebral Arterio-venous Malformation Excision Using Awake Craniotomy: Initial Experience of Two Cases

By Waleed Bin Ghaffar, Khalid Ahsan, Faraz Shafiq, Ather Enam,

This case series summarises the successful management of two cases with cerebral arterio-venous malformation (AVM). In first patient, it was located s...

A case of systemic lupus erythematosus with malignant pleural mesothelioma in a 42-year woman

By Yunyun Liu, Jianlin Tong, Xuefeng Ling, Wa Cao, Dr Leifang,

Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease characterized by inflammation. Malignant pleural mesothelioma (MPM) i...

Superficial Thrombophlebitis Caused By Extensively Drug Resistant Salmonella Enterica Serovar Typhi

By Anam Imtiaz, Irfan Ali Mirza, Qanita Fahim, Nargis Sabir,

Salmonella enterica serovar Typhi causes one of the most common blood stream infections, the typhoid fever. However, it can cause pyogenic...

Malignant melanoma metastasis to sigmoid colon; new endoscopic appearance detected for the first time

By Ugur Kesici,

Malignant melanoma (MM) develops as a result of malignant transformation of melanocytes. It accounts for 4% of all skin cancers. MM metastases usua...

Silver-Russell Syndrome- Orthodontic Perspective

By Zahra Khalid, Kashif Iqbal, Abdullah Jan, Asif Khurshid,

Silver-Russell syndrome (SRS) is a rare disorder characterized by prenatal and postnatal growth deficiency, a relatively large head size with trian...

Video-assisted thoracoscopic right inferior lobe resection for bronchial mucoepidermoid carcinoma in a 10-year child: A case report

By Fan Yang,

Bronchial mucoepidermoid carcinoma is a rare disease in the field of thoracic surgery, and it is even more rarer in children. A 10-year Chinese chi...

T-Cell Lymphoma Presenting With Bilateral Chylothorax: A Rarity

By Ibrahim Ethem Özsoy, Mehmet Akif Tezcan,

Chylothorax is the accumulation of chyle in the pleural cavity due to obstruction or injury arising in the thoracic duct or its large branches. In ...