Epub Ahead of Print

A case with neonatal onset Type 2 Neuronal Ceroid Lipofuscinosis: A novel mutation

By Ozgun Uygur, Mehmet Yekta Oncel, Pinar Gencpinar, Burcu Ozturk Hismi, Merve Saka Guvenc, Nihal Olgac Dundar,

Neuronal Ceroid Lipofuscinosis (NCL) is a lysosomal storage disorder that causes progressive neurodegenerative disease as a result of storage in ne...

MULTIMODAL IMAGING OF OPTIC NERVE DRUSEN IN A HYPEROPIC CHILD

By Sehnaz Ozcaliskan, Ozgur Artunay,

Optic nerve drusen (OND) are abnormal calcified acellular deposits located within the prelaminar portion of the optic nerve. They are usually asymp...

Late diagnosis of Paracetamol poisoning is always lethal in young adult

By Sehrish Naz, Safia Fatima, Muhammad Aamir,

Acetaminophen has a remarkable safety profile when prescribed in proper therapeutic doses but hepatotoxicity can occur when misused or after an ove...

Epithelial Cells in Patients with Fixed Orthodontic Appliances

By Rawabi Alsalhi, Lujain Alkhedhairi, Sultana Alsaikhan, Rabia Bilal, Shokria Ghneim,

The aim of this study was to assess the morphological changes of oral mucosa epithelial cells in contact with fixed orthodontic appliances using exfol...

Curative Effects of Valsartan Alone or Combined with Alpha-lipoic Acid on Inflammatory Cytokines and Renal Function in Early-stage Diabetic Kidney Disease

By Ziyuan Jiang, Zhen Tan, Fanqing Meng, Xiao Li,

The aim of this study was to compare curative effects of valsartan alone or combined with alpha-lipoic acid (ALA) on inflammatory cytokine indic...

Adult Necrotising Enterocolitis in a Breast Cancer Patient after First Cycle of Adjuvant Chemotherapy

By Fatima Tuz Zahra Shakir, Rizwan Sultan, Riaz Siddiqui, M. Zubair Shah, Ayesha Javed,

Chemotherapy-induced diarrhea has become a worrisome problem for the patients as well as the treating surgeons and oncologists because patient out...

Pure Lumbar Epidural Cavernous Hemangioma with Contralateral Symptoms Complicated by Spondylolisthesis

By Pan Qiao, Tiantong Xu, Wen Zhang, Wenyuan Ding, Rong Tian,

Pure spinal epidural cavernous hemangioma with contralateral symptoms is rarely reported. It will be very difficult to diagnose when it is complica...

Laparoscopic Cholecystectomy in Situs Inversus Totalis

By Falak Sher Malik, Usman Ismat Butt, Wasim Hayat Khan, Syed Muhammad Bilal, Muhammad Umar, Said Umer,

Situs inversus is a rare condition. It is characterised by reverse handed positioning of the internal viscera. Laparoscopic cholecystectomy is the ...

Emergent Transcatheter Aortic Valve Implantation as a Life-saving Procedure: A Primary Treatment Approach

By Emre Ozdemir, Fatma Kayaalti Esin, Selcen Yakar Tuluce, Mustafa Karaca,

Severe aortic stenosis (SAS) is the most common valvular heart disease in elderly patients. Untreated SAS is known to have 50% mortality within 2 y...

A Rare Injury in Children: Sternum Fractures

By Ibrahim Ethem Ozsoy, Mehmet Akif Tezcan,

Although there are a lot of data on intrathoracic and extrathoracic injuries associated with adult sternal fractures and how to manage them; but th...

Heparin-induced Thrombocytopenia in Pediatrics Following Cardiopulmonary Bypass

By Shi-min Yuan,

Heparin-induced thrombocytopenia (HIT) is an immune-mediated response to heparin administration. HIT following cardiopulmonary bypass (CPB) procedures...

Quality Evaluation of the Non-Variceal Upper Gastrointestinal Bleeding Guidelines/Consensuses via AGREE II Tools

By Yu Wang, Jun Guo, Youyi Rao, Gui Rong Xiao, Xinhua Zhao,

Non-variceal upper gastrointestinal bleeding (NUGIB) is a common disease in clinical practice; and many related guidelines/consensuses have been p...

Serum Des-gamma-carboxy Prothrombin for Diagnosis of Adult Primary Cancer in Liver

By Youdi Li, Jiu Chen,

Objective: To explore the diagnostic accuracy of serum des-gamma-carboxy prothrombin (DCP) in adult primary cancer in liver. Study Design: Descriptiv...

Two Years Remission of Type 2 Diabetes Mellitus after Bariatric Surgery

By Nauman Wazir, Muhammad Fahad Arshad, John Finney, Katie Kirk, Shivani Dewan,

Objective: To determine the influence of bariatric surgery on remission of type 2 diabetes mellitus (T2DM) in obese patients along with improvements i...

Diagnostic Value of Serum Biomarkers for Intrahepatic Cholangiocarcinoma

By Youdi Li, Yandi Huang, Jiu Chen,

Objective: To explore the diagnostic value of carbohydrate antigen 19-9 (CA 19-9) and carcinoembryonic antigen (CEA) for the diagnosis of intrahepatic...

Impact of Curative Effect of Laparoscopic and Open Partial Nephrectomy for Complex Renal Tumours on Renal Function

By Hong-mei Li, Peng Sun, Wen-zeng Yang, Zhen-yu Cui,

Objective: To explore the effect and safety of laparoscopic partial nephrectomy and open partial nephrectomy in the treat...

Effectiveness of Deep Breathing Exercises and Incentive Spirometry on Arterial Blood Gases in Second Degree Inhalation Burn Patients

By Summyia Siddique Malik, Naureen Tassadaq,

Objective: To find out the effectiveness of the deep breathing exercises and incentive spirometryon arterial blood gases in second degree inhalatio...

C-reactive Protein as a Screening Biomarker in Neonatal Sepsis

By Faisal Khan,

Objective: To measure validity of C-reactive protein (CRP) as screening test for neonatal sepsis (NS) and compare its screening validity between early...

Unilateral and Bilateral Percutaneous Kyphoplasty for Thoracolumbar Osteoporotic Compression Fractures

By Jin Tang, Wei-chun Guo, Jin-feng Hu, Ling Yu,

Objective: To compare the efficacies of unilateral and bilateral percutaneous kyphoplasty (PKP) in the treatment of thoracolumbar osteoporotic compres...

Comparison between Intramedullary Nailing and Minimally Invasive Percutaneous Plate Osteosynthesis in Treatment of Humeral Shaft Fractures

By Hang Yuan, Ran Wang, Jie Zheng, Yonghong Yang,

Objective: To compare the efficacy of intramedullary nailing (IMN) and minimally invasive percutaneous plate osteosynthesis (MIPO) in treatment of hum...

Hepatic Steatosis in Chronic Hepatitis B as Measured by Controlled Attenuation Parameter: Frequency and Distribution

By Shiying Nan, Yan Liang, Yundong Qu, Feng Liu, Lei Wang, Tao Li,

Objective: To determine the frequency of liver steatosis in chronic hepatitis B (CHB) patients measured by controlled attenuation parameter (CAP) and ...

Safety and Efficiency of Laparoscopic Femoral Hernia Repair with Preserved Uterine Round Ligament

By Mingxiao Guo, Dongfeng Chen, Haifeng Zhang, Chunlei Lu,

Objective: To evaluate the efficiency and safety of the transabdominal preperitoneal (TAPP) technique with or without preserved uterine round ligament...

May Nesfatin-1 be a Biomarker in Acute Mesenteric Ischemia?

By Cihad Tatar, Fatih Alper Ahlatci, Ufuk Oguz Idiz, Ali Emre Nayci, Said Incir, Orhan Agcaoglu, Cemile Idiz, Emre Balik,

Objective: To investigate the diagnostic value of nesfatin-1 in cases of intestinal ischemia and ischemia/reperfusion. Study Design: An experimental ...

Agreement Between 64-Slice Multidetector CT Angiography and Transthoracic Echocardiography in Detection of Extracardiac Findings of Congenital Heart Disease

By Adeel Asghar Malik, Furqan Ahmad, Sameera Amir, Javaid Asgher, Khalid Farooq,

Objective: To determine the degree of agreement between multi-detector computed tomography angiography and transthoracic echocardiography in diagnosti...

Association Between Neutrophil-to-Lymphocyte Ratio and Mortality in Neurological Intensive Care Unit Patients

By Muhammed Nur Ogun, Elif Yaksi,

Objective: To investigate the effect of neutrophil-lymphocyte ratio (NLR) on survival and mortality in patients who were interned in the Neurology Int...

Reinforced Laryngeal Mask in Pediatric Laparoscopic Surgery

By Xiao-li Sun, Jie Li, Zhen-yuan Wang, Ming-ying Li, Wei Duan, Nan Wu, Ou Yang,

 

Objective: To determine the frequency of reflux and aspiration in children subjected to reinforced laryngeal mask dur...

Pectoral Nerves I, II and Serratus Plane Blocks in Multimodal Analgesia for Mastectomy: A Randomised Clinical Trial

By Hammad Nabeel Najeeb, Syed Raza Mehdi, Athar Mukhtar Siddiqui, Syeda Kiran Batool,

Objective: To primarily assess pain score in first 24 hours in PECS (PECtoral Serratus) block group undergoing mastectomy; secondary objective was to...