Impact Factor 0.711 5 Year Impact Factor 0.735
Volume 32, 12 Issues, 2022

Epub Ahead of Print

A Systematic Review and Meta-Analysis on the Impact of Screen-time on the Social-Emotional Development of Children Under Five

By Areesha Ahmer, Mohammad Raza, Maha Azhar, Abdur Rahman, Jai Kumar Das, Sidra Kaleem Jafri,

Given the rising consumption of electronic media by children under five, it is crucial to study the impact of screen time (ST) on the social-emotional...


Thymosin Alpha 1 Plus Routine Treatment for The Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis

By Ailing Cao, Fanchao Feng, Xianmei Zhou,

This systemic review was conducted to assess the curative effect of thymosin alpha 1 in the acute exacerbation of chronic obstructive pulmonary diseas...


Prediction of In-Hospital Mortality After Emergency Laparotomy Using Glasgow Coma Scale, ASA Physical Status Classification and P-Possum Score

By Muhammad Asif, Saeed Bin Ayaz, Faran Hamid, Muhammad Nabeel Imran, Adnan Mehraj, Naheed Akhtar,

Objective: To determine the importance of the Glasgow Coma Scale (GCS), ASA Physical Status Classification System, and P-POSSUM score in predicting mo...


Management of Mandibular Condylar Fractures: A Comparison of Closed versus Open Reduction

By Syed Ammar Yasir, Ali Akhtar Khan, Sana Somair Waheed, Naseer Ahmad Kakar, Hamza Asif, Bisma Naeem,

Objective: To compare the closed reduction approach with open reduction (transparotid approach) in management of condylar fractures for parameters lik...


Reversion of Supra-Ventricular Tachycardia Through High Positive End-Expiratory Pressure During Mechanical Ventilation in Critically Ill Patients

By Hong-bo Wu, Shou-Yin Jiang, Shan-xiang Xu, Xiao Lu,

The Valsalva manoeuvre is widely recognised for its effectiveness in reverting supra-ventricular tachycardia (SVT) in patients with good coordination....


Pain Management in A Tertiary Care Setup: Assessing Patient Satisfaction and Pain Relief

By Muhammad Rashid Iqbal, Aijaz Ali, Mudassar Iqbal, Syed Majid Waseem, Moazam Ali, Muhammad Tahseen Talib,

The aim of this study was to assess the patient satisfaction and pain relief before and after interventions for chronic pain in a tertiary care pain c...


Effect of Blood Component Transfusion on Coagulation Function in Postpartum Haemorrhage

By Tianming Yan, Huiqun Xu, Fengling Li, Bili Zhang, Qiang Hong, Yijing Wang,

Postpartum haemorrhage (PPH) is a serious complication of pregnancy. In this study, patients with PPH were treated with blood component transfusion, a...


RENAL Nephrometry Scores and Perioperative Outcomes in Open Partial Nephrectomy

By Nadeem Bin Nusrat, Sana Kundi, Assad Ur Rehman, Nauman Zafar, Sarmad Imtiaz Bajwa, Saira Imtiaz,

Objective: To evaluate the efficacy of RENAL nephrometry scores in guiding open partial nephrectomy for renal malignancies and comprehends perioperati...


Coronary Artery Bypass Grafting in Young Adults

By Hina Inam, Abdul Ahad Sohail, Aimen Aamir, Kaleem S Ahmed, Narmeen Asif, Syed Shahabuddin Sharfuddin,

Objective: To evaluate the risk factors for early onset of coronary artery disease and assess the preoperative presentation, perioperative course, sur...


The Role of Edmonton Frailty Index in Determining the Postoperative Complications in Elderly: A Prospective Observational Study

By Seyda Canli, Cem Ece, Fulya Yılmaz Barut,

Objective: To explore the effect of Edmonton Frailty Index on the determination of postoperative complication and mortality rates in patients over 65 ...


High-Risk Influential Factors for Cardiovascular Diseases Among Young Adults

By Xiaowei Wang, Tianhong Yang, Jinxiu Liu,

The aim of this study was to compare high-risk influential factors for cardiovascular diseases among different young adults. It was a retrospective st...


Paediatric Pain Assessment and Perioperative Pain Management: A Survey of Practice in Teaching Hospitals in two Provinces of Pakistan

By Bushra Salim, Muhammad Ali Asghar, Shemila Abbasi, Saima Rashid, Khalid Maudood Siddiqui, Fauzia Anis Khan,

Objective: The primary objective was to map the practice of paediatric perioperative pain assessment and management among consultant anaesthetists wor...


Oxidative balance scores in adults with suicidal ideation: A nationwide Korean survey

By Jaehyuck Lee, Ki Dong Ko, In Cheol Hwang, Hong Yup Ahn,

This cross-sectional study investigated the relationship between oxidative balance (OB) scores and suicidal ideation among Korean adults. Data from 17...


Effects of PCSK9 Inhibitors On Glucose Metabolism in Hyperlipidaemia Patients: A Meta-Analysis

By Yujie Bai, Miao Hu, Jiayan Zhang, Ling Zhou,

This review assessed the impacts of PCSK9 inhibitors on glucose metabolism in patients with dyslipidaemia. A comprehensive search was conducted using ...


Prognostic Significance of CD4+ Tumour Infiltrating Lymphocytes in Patients with Non-Small Cell Lung Cancer Receiving PD-1/PD-L1 Inhibitors Therapy

By Qi-ming Zheng, Yuan-yuan Li, Ye-peng Wang, Guo-xiang Li, Zhi-gang Sun, Min Zhang,

CD4+ tumour infiltrating lymphocytes (TILs) have been found to produce a marked effect in anti-tumour immunity. In the study, the authors explored t...


Effectiveness of Cardiac Rehabilitation On Health-Related Quality of Life in Coronary Artery Disease Patients in Low and Middle-Income Countries

By ALIYA HISAM, Zia Ul Haq, Zohaib Khan, Sumaira Masood, Jill P Pell, Patrick Doherty,

This meta-analysis of published studies was calculated to determine the effectiveness of cardiac rehabilitation (CR) in terms of health-related qualit...


Sevoflurane Anaesthesia Increases the Risk of Perioperative Acute Kidney Injury than Propofol: A Meta-analysis of RCTs

By Mingjuan Li, Wenli You, Xiaosa Chi, Maomao Nie, Anmu Xie,

Sevoflurane has been suggested to lower the incidence of acute kidney injury (AKI) after heart surgery compared to intravenous anaesthetics. However, ...


Establishing a Newborn Screening Program: A Success Story from a Low-Resource Setting

By HAFSA RAIS, Lena Jafri, Sibtain Ahmed, Khadija Nuzhat Humayun, Salman Kirmani, Aysha Habib Khan,

The purpose of this communication was to assess the clinical effectiveness of an NBS program for congenital hypothyroidism (CH) in a tertiary care...


STN and GPi -Deep Brain Stimulation for Primary Cervical Dystonia

By Wei Tian, Guanyu Zhu, Shiying Fan, Fangang Meng, Anchao Yang, Jianguo Zhang,

Objective: To evaluate the safety and efficiency of deep brain stimulation (DBS) in the treatment of primary cervical dystonia (CD) and to compare the...


Efficacy and Safety of Biologics and Immunosuppressants in Maintenance Therapy for Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Network Meta-Analysis

By Liangdong Zhu, Minfang Guo, Siyu Gan, Keyu Li, Yong Fu, Xia Chen,

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a potentially life-threatening systemic autoimmune disease. This study aims ...


Association Between C-Reactive Protein and Suicidal Ideation: A Large-Scale Cross-Sectional Study

By In Cheol Hwang, Hong Yup Ahn, Yujin Park,

Studies of C-reactive protein (CRP) levels and suicidal behaviours have shown inconsistent results previously. This study investigated the relationshi...


Clinical Efficacy of Ganglioside Combined with Methylprednisolone in the Treatment of Spinal Cord Injury and its Effect on Inflammatory Response and Oxidative Stress Factors

By Dongliang Ren, Hui Li, Xiangdong Liu, Meihua Wang,

Objective: To determine the clinical efficacy of monosialotetrahexosylganglioside combined with methylprednisolone in treatment of spinal cord injury ...


The Effectiveness of Nicorandil in Heart Failure Patients: A Comprehensive Review and Meta-Analysis

By Tongge Mu, Kaixuan Tang, Yan Sun,

This meta-analysis aims to evaluate the effectiveness of nicorandil in treating heart failure by synthesizing evidence from diverse studies. This stud...


Robotic Versus Laparoscopic Approaches to Distal Pancreatectomy: Quality Assessment of The Current Evidence

By Attam Ullah Khan, Adan Khan, Arbab Danial,

Pancreatic surgery, associated with technical difficulties and high complication rates, remains a challenge for surgeons. The laparoscopic approach ha...


Long-Term Clinical Outcomes of the Transcatheter Aortic Valve System for Aortic Valve Stenosis

By Zijia Wu, Lulan Gao, Lei Chen, Zhihai Lin,

Objective: To evaluate the clinical safety and efficacy of the self-expanding transcatheter aortic valve system in Chinese patients with severe aor...


Fıstulectomy and Prımary Sphıncteroplasty (FIPS) for Transsphıncterıc Fıstula

By Ahmet Cihangir EMRAL, Merter Gulen, Bahadir Ege,

Objective: To evaluate the results of patients treated with fistulectomy and primary sphincteroplasty for uncomplicated perianal fistula. Study Des...


Peripheral Nerve Block Combined with Low-Dose General Anesthesia in Elderly Patients Receiving Hip Arthroplasty

By Ying Zhu, Yulin Liu, Hong Fu,

The study assessed the effectiveness and safety of nerve block combined with low-dose general anaesthesia in elderly hip arthroplasty patients, conduc...


COVID-19 Associated Neuromuscular Disorders-An Electrodiagnostic perspective Study

By Muhammad Tawab Khalil, Uzma Akhlaque, Umer Younis, Sana Arshad,

This cross-sectional study aimed to describe electro-diagnostic findings of neuromuscular disorders (NMD) associated with COVID-19 infection. Patients...


Outcome of Kangaroo Mother Care in Preterm And Low Birth Weight Newborn Babies

By Dr Mehwish Asghar, Dr Naseer Ahmed, Dr Neelam Dileep, Dr Asghar Ali Kerio, Dr Laila Pirzado, Dr Mubashir Hussain,

The objective of this study was to determine the outcomes of Kangaroo Mother Care (KMC) in preterm and low birth weight newborn babies. This prospecti...


Abnormal Brain Function in Systemic Lupus Erythematosus: A Meta-Analysis of Resting-State Functional Magnetic Resonance Imaging

By Xi Sun, Dongmei Fu, Yuting Mao, Zuanfang Li, Yinghong Lin, Jiaqiu Lin,

This meta-analysis investigated the neurophysiological underpinnings of systemic lupus erythematosus (SLE) by examining resting-state functional magne...


Frequency and Patterns of Multidrug Resistant Organisms among Ventilated Patients During The Coronavirus Disease-19 Pandemic

By Faiza Rezwan, Tazeen Fatima, Farheen Ali, Muhammad Nadeem, Nawal Salahuddin,

Objective: To determine the frequency of multidrug-resistant (MDR) bacterial isolates in respiratory specimens obtained from ventilated patients admit...


Treatment Outcome of Hematopoietic Stem cell Transplant in Fanconi Anaemia

By Hashim Khan, Prof Tariq Ghafoor, Tariq Azam Khattak, Nighat Shahbaz, Munazza Nabi Awan, Awais Siddiq,

Objective: To determine the outcome of Hematopoietic stem cell transplant (HSCT) in Fanconi anaemia patients. Study Design: Retrospective Study. ...


Antimicrobial Efficacy of Nanoparticle-Coated Gutta Percha: A Systematic Review

By Samira Adnan, Abishek Lal, Maham Muneeb Lone, Jamshed Ahmed, Isma Sajjad, Huma Shareef, Muhammad Sohail Zafar,

This systematic review aimed to evaluate the use of different nanoparticles for their ability to impart antimicrobial properties to conventionally ine...


Stem Cell Mobilization failure in Auto HSCT and Its Factors, A Single Centre Experience

By Dr Irsa Hidayat, Dr Mehreen Ali Khan, Dr Munazza Nabi Awan, Dr Awais Siddiq, Dr Sahla Riaz, Dr Qudrat Ullah,

Objective: To determine the mobilization failure rate and identify its associated factors in this part of world in order to identify patients at risk ...


Deep Vein Thrombosis as a Harbinger of Malignancy in the Emergency Department

By Mehmet Cihat Demir, Kudret Selki,

Objective: To determine whether malignancy was discovered within one year of follow-up in patients diagnosed with deep vein thrombosis (DVT) in the em...


Incisional Hernia Repair: Metanalysis on Laparoscopic and Open Surgical Repair

By Rosario Vecchio, Serena Scilletta, Eva Intagliata,

Despite the benefits of laparoscopic surgery, routine laparoscopic treatment of incisional hernia remains controversial. The aim of this meta-analysis...


Correlation of Peripheral Blood CD4/CD8 Ratio with Efficacy and prognosis in Patients with Non-Small Cell Lung Cancer Receiving PD-1/PD-L1 Inhibitors

By Qi-ming Zheng, Yuan-yuan Li, Ye-peng Wang, Guo-xiang Li, Zhi-gang Sun, Min Zhang,

The aim of this study was to investigate the predictive role of peripheral blood CD4/CD8 ratio in patients with non-small cell lung cancer (NSCLC) tre...


Outcomes of Auto Hematopoietic Stem Cell Transplant in Lymphomas, a Single Centre Study

By Dr Irsa Hidayat, Dr Mehreen Ali Khan, Dr Munazza Nabi Awan, Dr Awais Siddiq, Dr Noor Shamim, Dr Hashim Khan,

Objective: To determine the outcomes of auto hematopoietic stem cell transplant in lymphoma patients in terms of overall survival, disease free surviv...


Correlation of HER2 Expression in Gastric Carcinoma with Clinicopathological Parameters in the Omani Population

By ASIM QURESHI, Hana Al Julandana, Sara Al Barkhati, Ahmed Al Ghaithi, Asem Shalaby,

This retrospective study was conducted to determine the relation between Her2 expression and the clinicopathological and prognostic characteristics of...


The Association Between Facial Aging and Bone Mineral Density: A Mendelian Randomization Study

By Yabo Wang, Chao Zhen, Ziyu Wang, Lu Zhang, Yunzhen Chen,

This article aimed to assess the causative association between facial aging and bone mineral density (BMD) using Mendelian randomization (MR). In this...


Outcome of Hematopoietic Stem Cell Transplant in Beta-Thalassemia Major

By Hashim Khan, Tariq Ghafoor, Nighat Shahbaz, Tariq Azam Khattak, Uzma Rahim, Munazza Nabi Awan,

Objective: To determine the outcome of Hematopoietic stem transplant (HSCT) in beta-thalassemia major patients. Study Design: Descriptive Study. ...


Comparison of Pulmonary Index Score after Treatment with Salbutamol through Nebulizers Vs Metered – Dose Inhalers with Spacer Device for Treatment of Childhood Wheeze

By Arooj Khan, Shaista Azeem Khan, Syed Mohsin Ali Shah, Faizan Sadiq, Abdul Khaliq, Shahana Nisar,

The aim of this study was to compare the mean pulmonary index score after salbutamol delivery through nebulizers and metered-dose inhalers with spacer...


Oxidative Balance Scores In Cancer Survivors: A Nationwide Cross-Sectional Study

By Jaehyuck Lee, In Cheol Hwang, Hong Yup Ahn,

Although some studies have investigated the relationship between oxidative imbalance and adverse outcomes, there is a lack of data on oxidative balanc...


Association Between Mental Health and Metabolic Dysfunction–Associated Fatty Liver Disease

By Ji Hyeon Park, Yoo Jeong Lee, In Cheol Hwang, Hong Yup Ahn,

Depression has recently been suggested as a novel predisposing factor for metabolic dysfunction–associated fatty liver disease (MAFLD) among US adul...


Glomerular Filtration Rate By Gamma Camera Based Method: A Single Centre Interobserver Agreement Study

By Rebecca Sharoon, Zaigham Salim Dar, Muhammad Atif, Zeeshan Sikandar, Raana Fatima,

The objective of this study was to determine interobserver agreement in calculation of glomerular filtration rate by gamma camera-based method. It was...


Association Between Neuropsychiatric Event and Systemic Lupus Erythematosus Clinical Manifestation: A Meta-Analysis

By Ying Liu, Qianru Guo, Pingping Yu, Liyun Zhang, Na Yuan, Xinmei Song,

This research presents a systematic review and meta-analysis aimed at uncovering the clinical characteristics and investigating the underlying causes ...


Burn-out Among Pathology Residents in Pakistan

By HELEN MARY Mary ROBERT, Ahmed Ahson Khan, Humaira Tabassum, Shazia Nayyar, Samina Rehan, Quratulain Sareer,

Objective: To determine the frequency of burnout among pathology residents and the drivers contributing to its development at a tertiary care centre. ...


Role of Intralesional Vitamin D3 in The Treatment of Cutaneouswarts

By Dr Sabahat, Seemab Khaan, Noor Us Sabah,

Objective: To determine the effect of Intralesional Vitamin D3 injection in the treatment of cutaneous warts. Study design: Quasi experimental stud...


Association between Preoperative Expectations and Postoperative Satisfaction in Patients Undergoing Arthroscopic Rotator Cuff Repair

By Qilong Jiang, Yang Liu, Zhi Zhao, Yu Chen, Yu Deng,

The aim of this study was to determine the association between preoperative expectations (PE) and postoperative satisfaction for patients undergoing a...


Quackery in Health is Still Around: Pseudoscientific Healing Practices Across the Globe

By Ghulam Yaseen Veesar, Ather Akhlaq, Ahson Qavi Siddiqi, Abdul Ghafoor Shoro,

Fraudulent medical practices remain prevalent globally, fueled by digital platforms spreading false claims. This study analyzed 3,327 published studie...


Impact of Hands-on Cadaveric Dissection Courses on the Improvement of Surgical Skills of Ear, Nose and Throat Surgeon; A Survey from the Consultants and Postgraduate Trainees

By Saleh Khurshied, Altaf Hussain, Mujahid Raza, Nawal Khurshid, Maesum Ali, Mehrunnisa Nawaz,

A cross-sectional observational study at Pakistan Institute of Medical Sciences, PIMS Islamabad from April 2023 to May 2024 to determine the impact of...


Comparison of clinical outcomes of Hand-Assisted Retroperitoneoscopic with the Hand-Assisted Laparoscopic Donor Nephrectomy in Healthy Kidney Donors

By Umar Farooq, Asad Bashir, Nasrum Minallah, Fiaz Ahmad Touqeer, Zia Ul Haq Akram, Ali Asad,

Objective:  To compare the outcomes of Hand-Assisted Laparoscopic (HALS) and Hand-Assisted Retroperitoneoscopic (HARS) donor nephrectomy procedures. ...


Integration of Digital Modality in Virtual Classroom Enhances Nursing Students’ Inclusiveness in Learning: A Game Based Approach

By Sanam Hanif, Rabab Vadivala,

COVID-19 and virtual learning were transformative changes for educators and students in nursing education. This rapid shift necessitated educators to ...


Clinical Outcomes and Long-Term Effects of Consolidative Radiotherapy in Paediatric Hodgkin's Lymphoma

By Syed Muhammad Jawad Zaidi, Rabia Muhammad Wali, Naila Inayat, Sadia Anjum,

Objective: To evaluate the long-term effects and disease outcomes of consolidative radiotherapy in paediatric Hodgkin’s lymphoma (PHL). Study Des...


Association of HLA B51/5 in Patients of Behcet’s Disease Referred to a Tertiary Care Hospital of Pakistan

By Mustajab Alam, Usama Bin Khalid, Dawood Ahmad, Muhammad Omair Riaz, Muhammad Hussain, Muhammad Zain Arshad,

Objective: To determine association of HLA B51/5 in patients of Behcet’s disease (BD) in local symptomatic patients. Study Design: Cross Sectiona...


Assessment of Quality of Life in Mothers of Visually Impaired Children

By Zil E Rubab, Muneeba Tahir, Umaid Zafar, Noor Ur Rehman,

Objectives: To assess the factors that affect mother’s (QOL) and the association of various demographic variables with QOL of the respondents. De...


MALDI-TOF MS Application in M Protein Detection and Its Associations with Clinical Laboratory Findings in Geriatrics

By Jing Cheng, Yuying Zhang, Mingjie Cao, Yun Sun, Xiaomin Lv, Haiya Wang,

Currently, the methods used to detect M protein such as SPEP (serum M-protein electrophoresis), IFE (immunofixation electrophoresis) and sFLC (serum f...


Frequency of Disease Subsets and Spectrum of Organ Involvement and Interstitial Lung Disease Patterns in Patients of Systemic Sclerosis in Pakistani Population

By UMBREEN ARSHAD, Muhammad Ahmed Saeed, Muhammad Rafaqat Hameed, Maryam Aamer, Shamas U Din, Hafiz Yasir Qamar,

Objective: ILD to assess frequency of disease subsets and the spectrum of organ involvement, particularly focusing on interstitial lung disease (ILD) ...


Assessment Implementation Measures (Aim): The Journey Towards the Tool Validity

By Amara Butt, Yawar Hayat Khan, Muhammad Zeeshan Baig,

Objective: To establish the construct validity of the Assessment Implementation Measures (AIM) tool to accurately assess faculty perspectives on imple...


Attributes of Digital Leaders in Health Professions Education

By Sana Iqbal, Mashaal Sabqat, Zainab Akbar, Yawar Hayat Khan, Raheela Yasmeen,

Objective: This study investigates the essential attributes of effective digital education leaders (DELs) in health professions education, aiming t...


Pattern of Referral of Patients with COVID-19 for Psychiatric Consultation: Experience at a Multidisciplinary Hospital in Karachi, Pakistan

By Aisha Noorullah, Bilal Ahmed, Muhammad Yusuf Hafiz, Shahina Pirani, Murad M Khan,

Objective: To determine the referral patterns for psychiatric consultations among COVID-19 patients encompassing both the inpatient and emergency depa...


Musculoskeletal Ultrasound in the Diagnosis and Interventional Management of Common Pain Disorders - Analysis from a Physiatry Pain Clinic

By SARAH RAZAQ, Muhammad Aleem Arshad, Waseem Iqbal,

Objective: To determine the practical applications of musculoskeletal ultrasound (MSK US) in the precise diagnosis and optimal interventional manageme...


Comparison of the Combination of Interscalene Block and Superficial Cervical Block Anaesthesia with Interscalene Block Anaesthesia in Shoulder Surgery Operations

By Abdulhakim Şengel, Selcuk Secilmis, Evren Buyukfirat, Nuray Altay, Veysi Yazar, Mehmet Baki Bilsel,

Objective: To compare shoulder surgery patients who received interscalene block and superficial cervical block anaesthesia with those who received onl...


Balancing Benefits and Risks of the Use of Cage in Lumbar Spondylolisthesis Surgery: A meta-analysis

By Yunpeng Mao, Feng Yao, Chao Xu, Xinlin Wu, Yuhao Yang, Fuyong Zhang,

Lumbar spondylolisthesis is a prevalent spinal disorder for which the primary treatment approach involves surgical intervention, including reduction, ...