Epub Ahead of Print

Self and Peer Assessment of Teachers\' Attitude towards Teaching

By Ambreen Ansar, Robina Mushtaq Rizvi, Afsa Hussain, Aneela Nawaz, Abeera Zafar, Ammara Fayyaz,

Objective: To appraise the attitude of the teachers towards teaching and the factors affecting their attitudes, and compare self-assessed attitudes...


MRI Findings of Borderline Retroperitoneal Serous Cystadenocarcinoma: A Rare Entity

By Curcan Erbay, Elif Karadeli, Alper Parlakgumus,

Retroperitoneal serous cystadenocarcinoma is an extremely uncommon lesion. Here, we present MR imaging findings of a 40-year-old woman who was admi...


Impaction of Phytobezoar at Meckel\'s Diveticulum: A Rare Case of Small Bowel Obstruction

By Mohammad Masood Ur Rauf Hiraj Khan, Junaid Zia Hashmi, Naeem Lateef, Moazam Mumtaz, Farah Saleem,

Small bowel obstruction secondary to phytobezoars is a rare presentation in surgery. These are masses of undigested food and vegetables, which obst...


The Imaging Findings of Pulmonary Nocardiosis Mimicking Bronchiectasis: A Report of 2 Cases and Literature Review

By Lianmin Bao, Heping Lin, Ling Dong, Qing Zhang, Zongxiao Shangguan,

Nocardia species usually cause opportunistic infections, and the frequency of these infections is increasing owing to the growing population of imm...


Oxidizing Effect of Ozonated-Water Maintains Microbial Balance in the Oral Ecosystem

By Fathilah Abdul Razak, Md. Yusoff Musa, Husham Amra Mahmod Abusin, Nosizana Mohd. Salleh,

Application of ozone is recommended for sterilisation in dental procedures. This study explored the antimicrobial effect of 0.1 ppm ozonated-water ...


Hypohydrotic Ectodermal Dysplasia in an Indian Family

By Anish A Gupta, Swati S Gotmare, Megha Jain, Treville Pereira, Pooja Khare,

Hereditary ectodermal dysplasia (HED) is a rare genetic disorder chiefly affecting ectodermally derived structures including hair, nails, sweat gla...


Sequential Optic Neuritis: A Neuromyelitis Optica Spectrum Disorder

By Mehtab Alam, Mian Ayaz Ul Haq, Asif Iqbal, Kaleem Ullah, Danish Nabi,

Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune relapsing demyelinating disorder which often leads to severe disability typically t...


Montelukast and Budesonide for Children Cough Variant Asthma

By Wu Sun, Hai-yan Liu,

Objective: To determine the effects of combined treatment of montelukast and budesonide on young children with cough variant asthma, and their seru...


Chryseobacterium Indologenes as a Novel Cause of Bacteremia in Pediatric Patients: A First Reported Case and Literature Review

By Irfan Ali Mirza, Ayesha Khalid, Fatima Hameed, Anam Imtiaz, Ambar Ashfaq, Anam Tariq,

Chryseobacterium indologenes is a rare human pathogen. It is an emerging species, least frequently reported from pediatric age group and known to c...


Laparoscopic Surgery Combined with GnRH Agonist in Endometriosis

By Yu Yang, Weidong Zhu, Shuqiu Chen, Guangyuan Zhang, Ming Chen,

Objective: To determine the efficacy of laparoscopic surgery combined with GnRH agonist (GnRH-a) in treating infertile patients with endometriosis ...


Impact of Prostate Specific Antigen Level on Oncological Outcomes after Open Radical Prostatectomy

By Mustafa Sungur, Selahattin Caliskan,

Objective: To compare the impact of prostate specific antigen (PSA) on oncological outcomes in the patients with 4-10 and 10.01-20 ng/ml PSA level....


Traditional versus Percutaneous Transforaminal Endoforaminal Discectomy Effect on the Nervous System Function and Serum LEK, GFAP and PGE-2 in Patients with Senile Lumbar Spinal Stenosis

By Hejun Chen, Junlian Xue, Xinjiang Wu,

Objective: To compare the influence of percutaneous transforaminal endoscopic discectomy (PTED) and traditional operation on the nervous system fun...


Epidemiology and Treatment Outcomes of Sinonasal Tumors: A Single Institute\'s Experience in Pakistan

By Wajiha Anjum, Rab Nawaz Maken, Hasan Nisar, Ismat Fatima, Misbah Masood, Abu Baker Shahid,

Objective: To find the epidemiology and risk factors of sinonasal tumors and treatment outcomes in squamous cell carcinoma.
Study Design: An ob...


Differences of HBME-1 Expression in Thyroid Follicular Adenoma and Follicular Thyroid Carcinoma by Ultrasound-Guided Fine-Needle Aspiration Biopsy

By Junsong Wang, Li Xu, Xiaosen Xu, Xin Wang,

Objective: To investigate the differences in human bone marrow endothelial cell marker 1 (HBME-1) expression in thyroid follicular adenoma (FA) and...


Diffusion-Weighted Magnetic Resonance Imaging in Assessment of Primary Liver Cancer after HIFU Treatment

By Sheng Li, Sili Shi, Aiping Li, Huihui Liu, Lili Cai,

Objective: To determine the feasibility and role of diffusion-weighted magnetic resonance imaging (DWI) in the assessment of high-intensity focused...


Effect of Astragalus Polysaccharide on the Expression of VEGF and EGFR in Mice with Lewis Transplantable Lung Cancer

By Lichun Zhao, Yute Zhong, Jie Liang, Hongwei Gao, Nong Tang,

The aim of this study was to determine the effect of Astragalus polysaccharide (APS) on the expression of vascular endothelial growth factor (VEGF)...


Comparative Effects of Monosialoganglioside versus Citicoline on Apoptotic Factor, Neurological Function and Oxidative Stress in Newborns with Hypoxic-Ischemic Encephalopathy

By Shi-peng Liang, Qian Chen, Yi-bing Cheng, Ying-ying Xue, Hai-jun Wang,

Objective: To determine the comparative effect of monosialoganglioside versus citicoline on the content changes of serum apoptotic factors (PDCD5, ...


Conventional versus Minimally Invasive Vein Harvesting: A Clinical Audit of Wound Dehiscence Complications

By See Woan Shiang, Simon Jerome Vendargon, Syed Rasul Bin Ghouse Syed Hamid,

Objective: : To determine the wound complications post coronary artery bypass graft surgery (CABG) by conventional vein harvest technique (CVH) and...


A Novel Complication Following Retrograde Intrarenal Surgery: Retroperitoneal Hematoma

By Berat Cem Ozgur, Musa Ekici,

Retrograde intrarenal surgery (RIRS) is an efficient method for kidney stones with low complication rates. Reported here is an unusual complication...


Detection Rate of Thyroid Papillary Micro-carcinoma in Multinodular Goiter Surgery

By Bahri Ozer, Mustafa Sit, Gulali Aktas, Fatih Keyif, Ferdi Bolat, Hayri Erkol,

Objective: To determine the frequency of papillary thyroid micro-carcinoma (PTMC) in multinodular goiter (MNG) surgery, as well as in opposite thyr...


Small-Dose Ropivacaine Hydrochloride with Fentanyl versus Large-Dose of Ropivacaine Hydrochloride for Cesarean Section

By Jinwen Huang, Xia Liu, Shaoli Ding, Lei Zhu, Wenjun Yan,

Objective: To compare the effect of small-dose ropivacaine hydrochloride combined with fentanyl versus large-dose of ropivacaine hydrochloride for ...


Clinical and Demographic Features of 76 Children with Autism Spectrum Disorders at a Centre in Pakistan

By Ghazal Nadeem, Aleena Bibi, Bushra Suhaib, Suhaib Ahmed, Salman Ali,

In this cross-sectional study, 76 consecutive children with autism spectrum disorder (ASD) were studied for the clinical and demographic parameters...


Entecavir and Low Genetic Barrier Antiviral Agents for Hepatocellular Carcinoma in Hepatitis B Viral Cirrhosis: Propensity Score Matching

By Tao Li, Yundong Qu, Yan Wang, Chunlei Lin, Baohua Yang, Lei Wang,

Objective: To compare the reduction of hepatocellular carcinoma (HCC) risk between long-term treatment of entecavir and low genetic barrier antivir...


Myocardial Ischemia Presenting with Hiccups

By Shi-min Yuan,

Myocardial infarction/ischemia can be an underlying etiology and a major causative risk factor of cardiovascular hiccups. The objective of this sys...


Developing an Assessment-of-Clinical-Exodontia-Skills (ACES) Rating Scale for Undergraduate Dental Students

By Omer Sefvan Janjua, Abid Ashar, Tanzeela Khalid,

Objective: To develop assessment-of-clinical-exodontia-skills (ACES) rating scale for formative and summative assessment of undergraduate dental st...


Prenatal Diagnosis of b-thalassemia with Cell-free Fetal DNA in Maternal Plasma

By Lijian Zhao, Xuxia Liang, Haini Huang, Huihua Lan, Xin Wu, Chenhong Wang,

The aim of this study was to explore the feasibility of non-invasive prenatal genetic diagnosis of b-thalassemia with small fragments of cell-free ...


Need of Physical and Chemical Restraints: Experiences at Inpatient Psychiatric Ward in a Tertiary Care Hospital in Karachi, Pakistan

By Humera Saeed, M. Shameel Khan, Syeda Maheen Batool, Asma Akbar Ladak, Nadia Karim, Rabeeka Aftab,

In psychiatry, agitated / aggressive patients are often treated with de-escalation techniques. If this does not work, physical or chemical restrain...


Efficacy of Subconjunctival Injection of Bevacizumab in Regressing Corneal Neovascularisation

By Syed Shujaat Ali Shah,

Objective: To determine the efficacy of subconjunctival injection of bevacizumab in regressing corneal neovascularisation.
Study Design: Case s...


Rare Complication of the Hydrocephalus Case: Anal Extrusion of a Ventriculoperitoneal Shunt

By Omer Furkan Turkis, Ali Karadag, Erik H. Middlebrooks, Mehmet Senoglu,

Ventriculoperitoneal shunt (VPS) placement is an effective and most frequently used surgical method in the treatment of hydrocephalus, but the mech...


Frequency of Asthma and Atopic Diseases in Inflammatory Bowel Disease and Celiac Disease

By Fatma Yavuzyilmaz, Sebnem Ozdogan, Nafiye Urganci, Merve Kesim Usta,

Objective: To compare the frequency of asthma and allergic diseases in patients with inflammatory bowel disease and Celiac disease using internatio...


Retinal Ganglion Cell Complex Changes after Intravitreal Bevacizumab for Diabetic Macular Edema

By Muhammad Shaheer, Arooj Amjad, Zubair Saleem,

Objective: To measure the changes in ganglion cell complex as measured on optical coherence tomography (OCT) after intravitreal injection of bevaci...


Anterograde Reconstruction of Severe Bi-Canalicular Obstruction with Autogenous Saphenous Vein Graft: A Novel Surgical Technique

By Teyyeb Azeem Janjua, Bushra Akbar,

Severe lacrimal canalicular obstruction mandates a bypass surgery of conjunctivo dacryocystorhinostomy with Lester Jones tube or alternatively retr...


Comparing the Efficacy of Oral Chloroquine versus Oral Tetracycline in the Treatment of Cutaneous Leishmaniasis

By Fahmida Malik, Malik Muhammad Hanif, Ghulam Mustafa,

Objective: To compare the efficacy of oral chloroquine versus oral tetracycline in the treatment of cutaneous leishmaniasis (CL).
Study Desig...


Management of Leakage into the Abdomen due to the Involvement of Jejunum in the Incision Line

By Seracettin Egin,

Here, we present the management of a patient, developing severe peritonitis due to laceration of the jejunum, involving sutures applied to facial l...


Bosniak Classification and other Variables in the Prediction of Renal Cystic Masses

By Bugra Keseroglu, Berat Cem Ozgur, Sedat Tastemur, Lokman Irkilata, Ömer Gökhan Doluoglu, Cem Nedim Yücetürk,

Objective: To evaluate the variables of cystic renal lesions to predict the renal tumors.
Study Design: An observational study.
Place and Du...


Efficacy of Unibody Bifurcated Endovascular Stent-Graft Repair in the Treatment of Abdominal Aortic Aneurysm

By Chaohai Shi, Quan Chen,

Objective: To compare the clinical efficacy of unibody bifurcated endovascular stent-graft repair versus conventional open surgery for abdominal ao...


Efficacy of Catheter-directed Thrombolysis on Post-burn Deep Venous Thrombosis of Lower Extremity

By Guozheng Gao, Shugang Zhu, Zhen Xie, Jiasen Wang, Baohong Yao,

Objective: To observe the clinical effect of catheter-directed thrombolysis on deep venous thrombosis (DVT) of lower extremity after burn.
Stud...


Distribution of HLA-B*27 Subtypes in Patients with Ankylosing Spondylitis in Local Population

By Noor Afshan Lodhi, Muhammad Mukarram Bashir, Hamid Nawaz Tipu, Muhammad Hussain,

Objective: To compare the distribution of HLA-B*27 subtypes in healthy controls and in ankylosing spondylitis (AS) patients of different ethnic gro...


Effect of Irbesartan on Oxidative Stress and Serum Inflammatory Factors in Renal Tissues of Type 2 Diabetic Rats

By Xingang Zhao, Dongbin Yang, Weiwei Xu, Wen Xu, Zhengdong Guo,

Objective: To determine the effect of irbesartan on the activity of oxidative stress parameters of glutathione (GSH), superoxide enzyme (SOD) and m...


Influenza Virus Subtyping by Multiplex PCR during Winter Months of 2017-2018

By Misbah Noor, Saif Ullah Khan Niazi, Nadia Tayyab, Syed Adeel Gardezi, Eijaz Ghani, Muhammad Tahir Khadim,

Objective: To determine the frequency of infections caused by Influenza viruses, i.e. Influenza A (H1N1) pdm09, Influenza A (H3N2) and Influenza B ...


Myasthenia Gravis as a Cause of Failed Extubation Diagnosed by Diaphragmatic Ultrasound

By Priya Ramakrishnan, Shahla Siddiqui,

Myasthenia Gravis (MG) is an autoimmune disease of the neuromuscular junction which results in generalised weakness. Presentation varies and can of...


Comparison of Efficiency of TACE plus HIFU and TACE alone on Patients with Primary Liver Cancer

By Yuju Luo, Yu Jiang,

Objective: To compare efficiency of trans-arterial chemo-embolization (TACE) plus high intensity focused ultrasound (HIFU), and TACE alone on patie...


Comparison of Graft Survival between Fat Harvested from Abdomen and Medial Thigh for Facial Contour Deformity: A Randomised Control Trial

By Shohreh Ahmadi, Abdul Malik Mujahid, Husnain Khan, Farrukh Aslam Khalid, Muhammad Saleem, Muhammad Younas Mehrose,

Objective: To compare the graft survival between fat harvested from abdomen and medial thigh for facial contour deformity.
Study Design: Random...


Effect of Flap Fixation Technique in Modified Radical Mastectomy on Incidence of Postoperative Seroma Formation

By Erum Najeeb, Rakhshanda Rashid, Shaista Zaffar,

Objective: To determine the efficacy of flap fixation technique on formation of postoperative seroma after modified radical mastectomy.
Study D...


Effect of Phototherapy on Neutrophil VCS Parameters and White Blood Cells

By Nilgün Altuntas, Özlem Ceylan Dogan, Fatih Mehmet Kislal,

Objective: To investigate the effect of phototherapy (PT) on WBC parameters and neutrophil volume, conductivity and scatter (VCS) parameters.
S...


Effect of Prophylactic Ilioinguinal Neurectomy on Postoperative Groin Pain Following Lichenstein Hernioplasty

By Atif Sharif, Tasleem Akhtar, Mumtaz Akhtar, Irfan Malik, Muhammad Hanif, Naeem Zia,

Objective: To compare mean postoperative pain post-Lichenstein open hernioplasty with and without ilioinguinal neurectomy at six months.
Study ...


Effect of Dexketoprofene Trometamol on Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis

By Aziz Ari, Bunyamin Gurbulak, Hasan Okmen, Cihad Tatar, Ufuk Oguz Idiz, Muhammed Zubeyr Ucuncu,

Objective: To evaluate the efficacy of dexketoprofene trometamol solution following the administration of contrast agent for Endoscopic Retrograde ...


Post-tuberculosis Pneumocytoma

By Mustafa Kupeli, Hakan Nomenoglu,

Pneumocytoma is a rare benign tumor of the lung that usually manifests as a solitary pulmonary nodule. A 69-year lady, who had history of tuberculo...


Spectrum of Biopsy Proven Extraocular Muscle Tumours of Non-Thyroid Origin

By Tayyab Afghani, Hassan Mansoor, Amna Manzoor Mughal, Mohammad Asif, Muhammad Asif, Naeem Raza Hamdani,

Objective: To describe different types of primary extraocular muscle (EOM) tumours based on the results of imaging studies, peroperative clinical p...


Application of Non-invasive Positive Pressure Ventilation Combined with PetCO2 Monitoring for Patients with Chronic Obstructive Pulmonary Disease Combined with Severe Respiratory Failure

By Fu-tao Cao, Yu Cui, Jia Mao, Fang Wan, Su Tu,

Objective: To investigate the role of PetCO2 monitoring in non-invasive positive pressure ventilation (NPPV) treatment for chronic obstructive pulm...


Scoping Review of Crimean-Congo Hemorrhagic Fever (CCHF) Literature and Implications of Future Research

By Braira Wahid, Saba Altaf, Nabiha Naeem, Nimra Ilyas, Muhammad Idrees,

Crimean-Congo hemorrhagic fever (CCHF) is one of the severe forms of high-fatality hemorrhagic fever transmitted by bite of infected ticks or body ...


Presternal Goiter

By Matheo Augusto Morandi Stumpf, Andre Scartezini Marques, Camila Gabriella Da Costa Belonci,

An enlarging thyroid normally extends into the mediastinum, resulting in a presternal or substernal goiter, depending on its migration anteriorly o...


Malakoplakia of the Urinary Bladder and Unilateral Ureter

By Saddaf Hina, Aisha Hasan, Nadeem Iqbal, Muhammad Usman Shabbir, Abdul Ahad Ehsan Sheikh,

Malakoplakia is an unusual acquired granulomatous disease that can affect many systems including urogenital tract. It presents a huge diagnostic ch...


Risk Factors for Infectious Complications in Patients Undergoing Retrograde Intrarenal Surgery

By Demirhan Orsan Demir, Omer Gokhan Doluoglu, Yildiray Yildiz, Selen Bozkurt, Ali Ayyildiz, Arif Demirbas,

Objective: To investigate the risk factors that may cause urinary tract infection (UTI) in patients applied with retrograde intrarenal surgery (RIR...


Inhibitory Effect of Semen Litchi Drug Serum on the Proliferation of Human Hepatoma HepG2 Cells and Expression of VEGF and MMP-9

By Lichun Zhao, Peiliang Yu, Tao Yang, Gailian Zhou, Nong Tang,

Objective: To investigate inhibitory effect of semen litchi drug serum on proliferation of human hepatoma HepG2 cells and its effect on the express...


Combination of Oral Tranexamic Acid with Topical 3% Tranexamic Acid versus Oral Tranexamic Acid with Topical 20% Azelaic Acid in the Treatment of Melasma

By Fahmida Malik, Malik Muhammad Hanif, Ghulam Mustafa,

Objective: To compare the effect of combination therapies of topical 3% tranexamic acid versus topical 20% azelaic acid each combined with oral tra...


Relationship between the Quality of Sleep and Psychiatric Morbidity among the Patients of Head and Neck Tumours

By Usama Bin Zubair, Humza Mumtaz, Rizwan Taj,

Objective: To assess the difference between mean sleep (PSQI) scores in the patients with head and neck tumours with and without the psychiatric mo...


A Single Institution\'s Experience with Cytogenetic and MRD Outcomes in Pediatric Acute Lymphoblastic Leukemia

By Asim Amjad, Rabia Muhammad Wali, Sadia Anjum, Raheela Mansoor,

Objective: To determine the frequency of cytogenetic type and its significance in the prognostic outcome of the pediatric patients in acute lymphob...


Outcomes of Left Main Percutaneous Coronary Intervention

By Muhammad Nasir Rahman, Bilal Hussain, Azmina Artani,

Objective: To study the outcomes of left main percutaneous coronary artery (LMCA) revascularisation.
Study Design: A descriptive study.
Plac...


Expression and Significance of miR-126 and miR-145 in Infertility due to Endometriosis

By Fang Cheng, Luyan Lu, Huixia Wang, Hong Cheng, Dawei Zhang,

The aim of this study was to determine the expression and significance of miR-126 and miR-145 in endometrial tissues in the mid-luteal phase of pat...


Accessibility to Healthcare and Risk of Polypharmacy on Chronically ill Patients

By Suleyman Ersoy, Velittin Selcuk Engin,

Objective: To investigate the rates of polypharmacy (PP) and its relations with accessibility to health services in chronic patients in a primary c...


Metastatic Carcinoma of Endometrium from Primary Ovarian Serous Carcinoma Mimicking a Primary Uterine Tumour

By Mengfei Xu, Feng Zhou, Lili Huang,

A 44-year female was admitted to the hospital, complaining of vaginal bleeding. Ultrasound imaging revealed two masses in the pelvic cavity, measur...


Effectiveness of Direct Observation of Procedural Skills (DOPS) in Postgraduate Training in Urology at Institute of Kidney Diseases, Peshawar

By Liaqat Ali, Saima Ali, Nasir Orakzai, Naila Ali,

Objective: To determine the effectiveness of direct observation of procedural skills (DOPS) in the assessment and improving operative skills of pos...


Effect of Dexamethasone on TGF-b1/Smad3 Signalling Pathway in Airway Remodelling Model of Asthmatic Rats

By Yan Feng, Chang Yang, Wen Yan, Tao Jiang,

Objective: To determine the effect of dexamethasone on regulating the TGF-b1/Smad3 signalling pathway in airway remodelling model of asthmatic rats...


Effects of Parecoxib on Pain Threshold and Inflammatory Factors IL-1b, IL-6 and TNF-a in Spinal Cord of Rats with Bone Cancer Pain

By Jun Chen, Xiufeng Cong, Xiuzhu Zhan, Zheng Zhou, Wei Zheng,

Objective: To investigate the effects of parecoxib on pain threshold and inflammatory factors interleukin-1b (IL-1b), interleukin-6 (IL-6) and tumo...


Evaluation of Thin Layer Agar 7H11 for Direct Susceptibility Testing of Mycobacterium Tuberculosis Complex against Second Line Anti Tuberculosis Drugs on Smear Positive Specimens

By Ashfaq Hussain, Gohar Zaman, Luqman Satti, Aamer Ikram, Adeel Hussain Gardezi, Muhammad Tahir Khadim,

Objective: To evaluate performance of thin layer agar (TLA) 7H11 method for detection of ofloxacin (OFX) and kanamycin (KM) resistance in smear pos...


Cerebral Aneurysms due to Cardiac Myxoma

By Shi-min Yuan,

Cerebral aneurysms due to cardiac myxoma has been sporadically reported; however, the clinical features of this entity has not been fully elucidate...


Is Adenotonsillar Size a Significant Factor on Voice in Children Undergoing Adenotonsillectomy?

By Suleyman Emre Karakurt, Mehmet Ali Cetin, Ali Riza Yamur, Aykut Ikinciogullari, Serdar Ensari, Haci Huseyin Dere,

Objective: To determine whether adenotonsillar size is a significant determinant of voice in children who have undergone adenotonsillectomy.
St...