Epub Ahead of Print

Hemophagocytic Lymphohistiocytosis in a Pediatric Patient

By Saad Waheed, Saima Gillani,

Hemophagocytic Lymphohistiocytosis (HLH) is an uncommon but a potentially fatal disease characterized by high grade fever, hepato-splenomegaly, derang...


Anaesthetic Management of Tracheal Injury following Blunt Neck Trauma: An Unusual Late Presentation

By Muhammad Saad Yousuf, Mohammad Bin Pervez, Saulat Fatimi, Khalid Samad,

Tracheal injuries following blunt neck trauma are life threatening surgical emergencies with high risk of mortality. A high index of suspicion is nece...


Littoral Cell Angioma of the Spleen presenting with Thrombocytosis and Splenic Infarct

By Nazmi özer, Alper Sozutek,

Littoral cell angioma is a non-hematologic vascular neoplasm originating from littoral cells lining the splenic red pulp. The diagnosis is usually mad...


Familial Amyloidotic Polyneuropathy Type 1: A Hereditary Legacy

By Joel Pinto, Paulo Almeida, Flavio Pereira, Susana Cavadas,

Familial amyloidotic polyneuropathy type 1 (FAP 1) is a systemic autosomal dominant amyloidosis, associated with transthyretin mutation. It is charact...


Primitive Neuroectodermal Tumor of the Testis: A Case Report and Review of Literature

By Tarık Demir, Altay Aliyev, Mesut Seker, Cevper Ersoz, Ganime Coban, Haci Mehmet Turk,

A 21-year male presenting with left testicular mass and retroperitoneal lymphadenopathy underwent radical orchiectomy; and his pathological examinatio...


Cladophialophora Bantiana as a Cause of Rare Fungal Brain Abscess

By Zafar Ali, Muhammad Usman, Usama Rehman, Fatima Anwar,

Cerebral phaeohyphomycosis refers to central nervous system infection caused by dematiaceous molds, which have many genuses. Cladophialophora bantian...


Damage Control Surgery Saves Patient with Gastric Lymphoma from Radical Gastrectomy

By Gang Chen, Min-min Zhang, Jun-min Zhu, Jie Mao, Yu-min Li,

The concept of damage control surgery was first introduced in the 1990s. It has great significance in the treatment for critically ill patients, which...


Intentional Replantation for a Right Mandibular Premolar: A Case Report

By Sheng-jin Xue, Qing-bin Zhang, Wei-qun Guan,

The present study reports a case of intentional replantation (IR) for a right mandibular second premolar (#45). For the present case, root canal retre...


Synchronous breast cancer and renal leiomyoma; a case report

By Caner Ediz, Neslihan Kaya, Serkan Akan,

We present a case of a 49-year Turkish woman who had synchronous renal leiomyoma and breast cancer. The patient was evaluated for a suspicious breast ...


Myomectomy for a large submucosal fibroid at the time of caesarean section: A case report

By Jian An, Jinxiao Lin, Pengming Sun,

Submucosal uterine fibroids are usually associated with infertility and miscarriage. Hence, term pregnancies with large submucosal fibroids are rare i...


Primary T-Cell Lymphoma of The Parotid Gland

By Osman Ilkay Ozdamar, Gul Ozbilen Acar, Servet Karaca, M Tayyar Kalcioglu, Tulay Zenginkinet,

Primary malignant lymphomas of parotid gland are very rare. Most are B-cell lymphomas, and T-cell lymphomas are very rare. Unfortunately, fine needle ...


Gastric adenocarcinoma of fundic gland type: A clinicopathological observation

By Lixin Wang, Gang Chen, Jinggui Jiang,

We investigated the clinicopathological features, diagnosis and differential diagnosis of a patient with gastric adenocarcinoma of the fundic gland ty...


Pancreatic acinar cell carcinoma presenting with diffuse pancreatic enlargement: A case report

By Hongwei Li, Yaping Wu, Xiaodan Xiang, Jun Zhou, Qian Li,

Pancreatic acinar cell carcinoma (PACC) is a rare tumor of the exocrine pancreas. It accounts for only 1% of all pancreatic malignancies. A 39-year-ol...


A rare case of posterior interosseous nerve palsy post-venepuncture

By Raymond Dieu Kiat Yeak, Yee Yee Yap, Nizlan M Nasir,

Wrist drop post-venepuncture is uncommon. There has been reported cases of direct injury to the radial nerve during venepuncture but to our knowledge,...


Acrometastasis of Laryngeal Carcinoma to the Finger: A Case Report

By Cengiz Karacin, Sema Turker, Dogan Yazilitas, Tulay Eren, Tugba Taskin Turkmenoglu,

Distant metastasis of laryngeal carcinoma occurs at a rate of  4%-12%, with the most common sites being the lungs, liver and bone. Acrometastasis oc...


Vaginal Leiomyoma Presenting As Pelvic Organ Prolapse In Pregnancy

By Saida Abrar, Dr Raheela Mohsin,

Vaginal leiomyomas are extremely rare in pregnancy. These can present in a variety of ways. They can cause mechanical obstruction leading to maternal ...


Pituitary Stalk Interruption Syndrome in a 54-year adult male: a case report and review of literature

By Lu Wenwen, Fan Xiaofen, Yu Guoyou, Wu Guolin,

Pituitary stalk interruption syndrome (PSIS) is a rare disease with isolated growth hormone deficiency or multiple anterior pituitary hormone deficien...


Use of Eculizumab in Thrombotic Microangiopathy Associated with Hematopoietic Stem Cell Transplantation

By Sinan Demircioğlu, Ali Dogan, Cengiz Demir,

Thrombotic microangiopathy (TMA) associated with hematopoietic stem cell transplantation remains a difficult complication due to its high mortality ra...


Craniofacial Langerhans Cell Histiocytosis– A Rare Case Report

By Suriyakala M, Dr Sreela L.s, Dr Twinkle S Prasad, Dr Philips Mathew, Dr Admaja K Nair,

           Langerhans Cell Histiocytosis (LCH) is a rare haematological disorder characterized by accumulation and abnormal proliferation of...


A difficult road for percutaneous coronary intervention in a single coronary artery anomaly

By Kerim Esenboga, Emir Baskovski, Nil Ozyuncu, Eralp Tutar,

Coronary artery anomalies are frequently asymptomatic clinical entities associated with variable prognosis. Single coronary artery anomaly is a rare t...


A Young Man with a Rare Case of Adrenal Incidentaloma

By Usama Bin Khalid, Qurat Ul Ain, Muhammad Aamir, Shahrukh Shah, Shakeel Ahmad, Zujaja Hina Haroon,

Adrenal incidentalomas (AIs) are adrenal masses discovered as incidental finding, often on imaging studies, unrelated to adrenal disorders. Sometimes,...


Comparison of Brachiobasilic Transposition Arteriovenous Fistula Outcomes among Diabetic and Non-diabetic Patients: A Case Controlled Study

By Zia Ur Rehman, Waryam Muhammad Saleh, Anum Sadruddin Pidani,

Diabetes is considered a risk factor for arteriovenous fistula failure and increased perioperative complications but this view is not proven for patie...


A Case of Diffuse Large B Cell Lymphoma With Cardiac Involvement Incidently Diagnosed on Cardiac Imaging

By Asif Husain Osmani,

Cardiac lymphomas, either primary or secondary, are mostly of B cell lineage; among which, diffuse large B cell lymphoma (DLBCL) is the most common. S...


Colonic Metastasis From Primary Tonsillar Squamous Cell Carcinoma: A Rare Cause of Large Bowel Obstruction

By Tayfun Kaya, Semra Demirli Atıcı, Dudu Solakolu Kahraman, Huseyin Salih Semiz, Duygu Kahraman,

Tonsillar squamous cell carcinoma is a subtype of head and neck cancers which rarely metastasizes to the colorectal system. Colonic metastasis seconda...


Chryseobacterium indologenes bacteraemia: a potential cause of early-onset neonatal sepsis in a full-term baby

By Siba Prosad Paul, Paul Anthony Heaton,

Chryseobacterium indologenes is considered as an emerging pathogen known to cause pneumonia, bacteremia, and meningitis in children.  It has been rep...


Pleomorphic Adenoma Of Minor Salivary Glands: A Case Report

By Sahar Usman, Sufyan Ahmed, Sana Iqbal, Ayesha Aslam,

Pleomorphic adenoma is a benign tumor of salivary glands. Pleomorphic adenoma arising from minor salivary glands is very rare and presents with a mino...


Rare Presentations oF Rapidly Growing Liposarcomas

By Arifa Javed, Jafar Haghshenas, Scott Sholem, Farooq Shahzad, Jamshed Zuberi,

Liposarcomas (LSs) are a rare form of malignant tumors. They are the most common primary neoplasms of the retroperitoneum. While these tumors rarely m...


Scabies Surrepticius (Bullous Scabies) Presenting As Bullous Impetigo In A Child: A Case Report

By Rao MUHAMMAD ABID Khan, Asma Muzammil, Sualleha Siddiqi, Shazia MUHAMMAD Qasim, Ali Nadeem,

Bullous scabies (BS) is a rare and atypical presentation of scabies usually affecting elderly males during seventh decade of life. BS is characterized...


A Case of Lung Abscess Mimicking Lung Cancer

By Nevhiz Gundogdu,

The radiological appearance of lung abscess is nonspecific and can masquerade as a mass lesion during the early phase. The treatment is primarily medi...


Severe Hyponatremia of 103 Mmol/L With No Symptoms in A 65 Year Old Man – A Case Report

By LAWSON EKPE, Emin Emin, Lawrence Onuche, Kingsley Osuji,

Hyponatremia is regarded as the most common electrolyte imbalance among hospitalized patients. Most hyponatremic conditions present with various degre...


Radiologic and histopathologic features of a neck-localized follicular dendritic cell sarcoma: A case report and literature review

By Jing Zeng, Xi Xu, Changzheng Shi, Liangping Luo,

Follicular dendritic cell sarcoma (FDCS) is an uncommon tumour. The pathological features of FDCS have been extensively described in literature, but t...


Radiologic and histopathologic features of a neck-localized follicular dendritic cell sarcoma: A case report and literature review

By Jing Zeng, Xi Xu, Changzheng Shi, Liangping Luo,

Follicular dendritic cell sarcoma (FDCS) is an uncommon tumour. The pathological features of FDCS have been extensively described in literature, but t...


Radiologic and histopathologic features of a neck-localized follicular dendritic cell sarcoma: A case report and literature review

By Jing Zeng, Xi Xu, Changzheng Shi, Liangping Luo,

Follicular dendritic cell sarcoma (FDCS) is an uncommon tumour. The pathological features of FDCS have been extensively described in literature, but t...


Median Arcuate Ligament Compression on Celiac Trunk During Liver Transplantation Procedure

By Kaleem Ullah, Shams Uddin, Abdul Wahab Dogar,

Low insertion of median arcuate ligament (MAL) can cause compression over celiac trunk with subsequent complications. During liver transplantation pro...


Gossypiboma: The Forgotten Foreign Bodies and Surgeon’s Nightmare

By Faiza Ahmed, Usman Akbar, Adil Khan, Mustafa Rahim,

Gossypiboma, first described by Wilson in 1881, is a term that originated from the Latin word Gossypium (meaning “cotton”) and suffix -oma (mea...


A Large Hydatid Cyst in the Brain of a 10-year Child: A Case Report

By Muhammad Ashraf, Shakeel Ahmed, Shahryar Ahmad, Ashar Ahmad,

Hydatid cyst is the larval form of the parasite, Echinococcus Granulosus. We operated upon a case of giant hydatid cyst in the left cerebral hemispher...


Right Ventricular Blood Cyst in An Adult Autosomal Dominant Polycystic Kidney Disease Patient: An Unusual Association

By Ersin Çagrı Şimşek, Dilek Oncel, Erdem Ozel,

Blood cysts of the heart are unusual primary cardiac tumor-like masses, which are usually located on the cardiac valves. These are very rare in adults...


T-cell acute lymphoblastic leukemia in an infant: a case report and review of literature

By Neelum Mansoor, Naeem Jabbar,

A high index of suspicion of acute leukemia in infants presenting with atypical clinical and laboratory features is of paramount importance to avoid t...


Simple Congenital Hamartoma Of Retinal Pigment Epithelium: A Case Report

By Tayyaba Gul Malik,

A 45-year female presented in outpatient department of a tertiary care hospital of Lahore with dimness of vision in right eye. History revealed that t...


A Rare Presentation of Extramedullary Hematopoiesis: Perirenal Masses

By Selahattin Durmaz, Cennet Sahin, Muzaffer Basak, Sukru Mehmet Erturk,

Extramedullary hematopoiesis (EMH) is a physiological compensatory mechanism that develops in response to ineffective or insufficient hematopoiesis. A...


A Rare Co-Existence of Multiple Cerebral Cavernous Malformations and Pleomorphic Adenoma of The Parotid Gland in Myotonic Dystrophy

By Sadaf Iftikhar, Muhammad Zeeshan Sarwar,

Myotonic dystrophy is an autosomal dominant inherited disorder primarily affecting the muscle function. Myotonia, progressive muscle weakness and wast...


Contralateral Recurrence of A Lumbar Juxtafacet Cyst Following Spontaneous Resolution: A Case Report

By Can Sarica, Furkan Kucuk,

We present a patient who had spontaneous resolution of a right L3/4 lumbar juxtafacet cyst (LJFC) and in whom, 2.5 years after regression of the previ...


Solitary Langerhans Cell Histiocytosis of Skull: Case Report with One- year Follow-up

By Muhammad Junaid, Ali Afzal, Syed Sarmad Bukhari,

Langerhans cell histiocytosis (LCH) is a rare disorder characterized by increased production of Langerhans-type histiocytes. It is more common in the ...


Adult Retroperitoneal Mature Cystic Teratoma Masquerading as Non-Endocrine Primary Adrenal Tumor

By Fatima Tuz Zahra Shakir, Rizwan Sultan, Riaz Siddiqui, M Zubair Shah, Ayesha Javed,

Teratomas belong to non-seminomatous germ cell tumors and they originate from totipotent germ cells. They are mostly made up of tissues derived from a...


Histiocytic Sarcoma with Invasive Urothelial Carcinoma of Urinary Bladder: A Case Report and Literature Review

By Ayşegül İsal Arslan, Sevil Karabag, Murat Akgul,

We report a rare case of histiocytic sarcoma in association with invasive urothelial carcinoma involving the urinary bladder. A 67-year male patient w...


Carpometacarpal Joint Dislocations as a Rare Cause of Hand Pain: A Case Report

By Ali Çelik,

Carpometacarpal joint dislocations represent not more than 1% of all hand injuries due to stable joint structures and high energy trauma mechanism. Un...


Control of Oesophageal Tumour-Related Bleeding With A Temporary, Fully Covered Self-Expandable Metallic Stent (Sems) Insertion: A Case Report

By Muhammad Zeeshan Siddique, Muhammad Saqib, Jhanzeb Iftikhar, Muhammad Aasim Yusuf,

The role of metallic stents in the management of refractory variceal bleeding is now well established; however, they have been rarely used in treatmen...


It does exist! Traumatic hemorrhage in septum pellucidum

By Murat Seyit, Arif Osun, Atakan Yilmaz, Mert Ozen, Duygu Aras Seyit,

Although bleeding into the septum pellucidum often occurs in the presence of a tumour, trauma-induced septal pellucidum hemorrhage has not been report...


Anabolic Steroid-Induced Reversible Cardiomyopathy in A Young Non-Athletic Female

By Uzma Gul, Muhammad Shahid,

Anabolic androgenic steroid (AAS) abuse is widespread nowadays, not only in athletes but in non-athletic populations and rapidly becoming a public hea...


Rasmussen's Encephalitis: A rare cause of intractable seizures

By Muhammad Bilal Mazhar, Attiya Fatima, Muhammad Haroon Hamid,

Rasmussen’s encephalitis (RE) is a rare chronic progressive inflammatory disease of the brain that results in difficult-to-control seizures (mostly ...


Renal Cell Carcinoma Of Pelvic Kidney With Atypical Nodal Metastasis: A Diagnostic Challenge

By Roshane Shahid Rana, Muhammad Hammad Ather,

Ectopic pelvic kidney is a known congenital anomaly; however, presence of renal cell carcinoma (RCC) in an ectopic kidney is rare with evidence availa...


Atypical Presentation of A Primary Thymic Adenocarcinoma: A Case Report

By Hasan Ersöz, Ebru Cakir, Utku Oflazoglu, Berna Dernek,

Primary thymic adenocarcinomas are extremely rare and aggressive tumors. In this report, clinical and histopathological findings of this rare entity a...


A Case of Foveoschisis Associated With Ornithine Aminotransferase Deficiency and Gyrate Atrophy

By Sehnaz Ozcaliskan, Sevcan Balci, Ozgur Artunay,

      Gyrate atrophy is a metabolic disorder characterized by typical progressive circular chorioretinal atrophy, myopia and early developmental ...


Epithelioid inflammatory myofibroblastic sarcoma with leukemoid reaction

By Yuan Yuan Wan, Cheng Li Miao, Shi Bo Liu, Tong Zhang, Cheng Hua Luo,

Epithelioid inflammatory myofibroblastic sarcoma (EIMS) is a rare and aggressive inflammatory myofibroblastic tumor (IMT) variant. Our report identifi...


Mucormycosis of Maxilla: An Enigma To The Clinician

By Suman Sen,

Mucormycosis is an acute opportunistic infection caused by a saprophytic fungus found in soil, and decaying fruits and vegetables. It is a rapidly pro...


A Rare Case of Horseshoe Kidney in a Patient with Leriche Syndrome

By Anıl Özen, Isa Civelek, Görkem Yiğit, Hakki Zafer Iscan,

Horseshoe kidney (HSK) is one of the most common congenital renal fusion anomalies. Difficulties are encountered during surgery of aortic diseases ass...


Non-Surgical Management of Lingual Hemangioma by Combined Sclerotherapy and Cryotherapy: A Case Report

By SHAUL HAMEED KOLARKODI, Muhammad Qasim Javed, Mohammed Rafeeq P K, Dhafer Alasmari, Mohammed Faiz C P,

Hemangioma is frequently seen benign tumor of vascular origin, typed into capillary and cavernous hemangiomas based on the nature of vessels in the le...


Fish Bone-Induced Pericardial Hemorrhage Resulting in A Misdiagnosis of Acute Myocardial Infarction: A Case Report

By Qin Zuoan, Liagnqing Ge,

Fish bone intake is a common clinical event, but serious complications resulting from the ingestion of fish bones, such as perforations in the stomach...


Scapular Winging Secondary to Iatrogenic Spinal Accessory Nerve Lesions: A Case Report

By Selin Ozen, Sacide Nur Cosar Saracgil, Sevgi Ikbali Avsar, Sehri Ayas,

Motor innervation of trapezius and sternocleidomastoid (SCM) muscles is provided solely by the spinal accessory nerve (SAN).  SAN palsy most often oc...


Saved by the clot in superior vena cava injury: a case report

By Pratikshya Thapaliya, Tanveer Ahmad, Nazish Sikander, Misauq Mazcuri, Ambreen Abid,

Penetrating neck injuries (PNIs) can cause injuries to great vessels. Superior vena cava (SVC) injury from stab to neck is rare and when it occurs,  ...


Guillain-Barre Syndrome: a rare complication of organophosphate poisoning

By Dr Shaheen, Shameem Kauser, Irfan Ahsan,

Organophosphate poisoning is common following accidental or suicidal ingestion. Cases have been reported with different neurological consequences incl...


Granulomatous Inflammation of Greater Omentum Caused by a Migrating Fish Bone

By Qi Chao Wang, Yan Wan Wu, Nan Ya Wei, Tao Xu Li, Tao Fan, Jie Ying Song,

Fish bone is the most common ingested gastrointestinal foreign matter and less than 1% perforate. However, a fish bone penetrating the gastrointestina...


An Extraordinary Case of Isolated Duodenal Injury After Blunt Abdominal Trauma

By Mehmet Zeki Buldanlı, Nuray Colapkulu, Oktay Yener, Ibrahim Ali Ozemir,

Duodenal injuries are rare due to their preserved retroperitoneal location. They are mostly observed after deep penetrating or high impact blunt traum...


Follicular variant of papillary thyroid carcinoma presenting with thoracic vertebral metastasis: A rare phenomenon

By Özkan Özger, Necati Kaplan,

Follicular variant of papillary thyroid carcinoma (FV-PTC) often follows nodal spread and hematogenous spread is rare. A 77-year male presented to ...


A Rare Case of Female Bladder Outlet Obstruction: Severe Introital Stenosis

By Muhammed Fatih Simsekoglu, Oktay Ozman, Mehmet Hamza Gultekin, Bulent Cetinel,

Herein, we report a rare case of severe introital stenosis in a 22-year female who presented with obstructive voiding symptoms and inability to have s...


Unusual Appearance of Nasal Collagenous Fibroma ( Desmoplastic Fibroblastoma ) on Imaging

By Xiaolong Liu, Xiang Guo, Linsheng Wang, Yueqin Chen, Hao Yu, Zhanguo Sun,

Collagenous fibroma (CF) is a benign soft tissue tumour with good prognosis. Preoperative imaging diagnosis is essential to avoid unnecessary extended...


Pneumomediastinum in an accidental chlorine gas exposed victim

By Muhammad Akbar Baig, Maaz Salahuddin,

Chlorine is an irritant gas which is implicated in inhalational exposures which can affect the respiratory system leading to complications. We report ...


Cutaneous T Cell Lymphoma Predisposing to Recurrent Infective Endocarditis by Methicillin-Resistant Staphylococcus In A Patient with Intracardiac Defibrillator

By Muhammad Azam Shah, Muhammad Adil Soofi, Faisal Alsmadi, Muhammad Amin Ur Rehman, Faisal Abdullah Alghamdi,

Cutaneous T cell lymphoma (CTCL) is a rare group of extra-nodal non-Hodgkin's lymphomas resulting in infiltration of the skin by malignant cells. ...


Disseminated nocardiosis with ocular involvement in a patient with ANCA-associated vasculitis

By Ayşe Bahar Keleşoğlu Dinçer, Serdar Sezer, Mucteba Enes Yayla, Gulay Kinikli,

A 62-year male patient, diagnosed with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), developed proptosis and decrease in vis...


Spontaneous cervical epidural abscess caused by serratia marcescens: A case report

By Idris Sertbaş, Derya Bayirli Turan, Mete Karatay,

Serratia marcescens infections are very rare and are usually occur in the form of nosocomial and opportunistic infections. The subjects usually have s...


BRUCELLA PROSTHETIC INFECTION IN A PATIENT WITH TOTAL KNEE PROSTHESIS: A CASE REPORT

By Sabit Numan Kuyubasi, Sermet Inal, Alaadin Oktar Uzumcugil, Sevil Alkan Ceviker, Bunyamin Ari,

Brucella infection is often an occupational disease of veterinarians, agricultural workers and slaughterhouse workers. The infection is generally spre...


Role of Recombinant activated factor VIIa (rFVIIa) in bleeding mycotic aneurysm of abdominal aorta

By Irfan Ahsan, Karimullah Makki, Sidra Rauf, Shaheen Sultan,

Mycotic aortic aneurysm is an infective disease of aorta with high mortality rate despite surgical repair. Recombinant activated factor VIIa (rFVIIa)...


Double Balloon Enteroscopy in A Pregnant Woman Wıth Peutz-Jeghers Syndrome

By Mesut Akarsu, Soner Önem, Zarni Htway, Ozan Cengiz, Suleyman Dolu, Leyla Iyilikci,

Peutz-Jeghers syndrome is an autosomal dominant disorder characterized by multiple hamartomatous polyps and muco-cutaneous pigmentation. Most polyps a...


Spontaneous Forniceal Rupture Identified By Point of Care Ultrasound: Case Report

By Ali Çelik, Mehmet Altuntaş,

Spontaneous forniceal rupture is one of the rarest diagnosis of abrupt onset abdominal pain. Moreover, urolithiasis is the most prevalent cause and co...


SRD5A3-CDG: a patient with a novel variant and brain neoplasm

By Cigdem Seher Kasapkara, Asburce Olgac, Betul Emine Derinkuyu, Ulkuhan Oztoprak, Jaak Jaeken,

Congenital disorders of glycosylation (CDGs) are a large group of genetic diseases with impaired glycosylation of glycoproteins and glycolipids, and g...


Unusual Sites of Leiomyosarcoma: A Medley of 3 Interesting Cases

By Bushra Siddiqui, Shahbaz Habib Faridi, Asfa Shams, Jowairiah Hassan,

Leiomyosarcomas are malignant tumours arising from smooth muscle cells. They are rapidly growing tumors with aggressive behaviour and poor prognosis. ...


Initial Experience in Ablation Of Non-Coronary Cusp Pvcs By Using High Density Mapping System (Rhythmia): A Case Report

By Muhammad Asad, Qurban Hussain Khan, Azmat Hayat, Rehana Khadim,

Idiopathic premature ventricular contractions (PVCs) most often occur under or above the semilunar valves from right ventricular outflow tract and les...


Cecal Dıvertıculıtıs: A Dıagnosıs To Keep In Mınd When Evaluatıng Acute Appendıcıtıs

By Hakan Bolukbasi,

Caecal diverticulitis is a rare cause of right lower quadrant abdominal pain. As its symptoms mimic those of acute appendicitis, the final diagnosis i...


Insidious onset of Localised Small Intestinal Perforation by ingested Plastic Fork

By Serhan Yilmaz, Hüsnü Aydın, Hakan Bolukbasi,

Ingestion of a foreign body is generally observed in psychiatric patients and children. Adult healthy individuals may also swallow a foreign body unin...


Nasopharyngeal Tuberculosis

By Shanila Ahmed, Syed Muhammad Mustahsan, Bushra Jamil, Faiza Ilyas,

Tuberculosis is a well known communicable infectious disease and can involve almost any organ of the body, but mostly lungs. Upper respiratory tract i...


Neurological Recovery with Interferon-Gamma Treatment in Friedreich's Ataxia

By Hande Gazeteci Tekin, Erturk Levent,

Friedreich's ataxia (FA) is a rare, progressive, and degenerative hereditary disorder caused by a deficiency of frataxin protein. This disease is ...


Two Cases of Interrupted Inferior Vena Cava with Azygos/Hemiazygos Continuation

By Saerah Iffat Zafar, Aliya Halim, Waqas Khalid, Mobeen Shafique, Hina Nasir,

Interrupted inferior vena cava (IVC) is a rare disease, occurring either in isolation or in association with asplenia or polysplenia syndromes. Infrah...


Neurobrucellosis Manifesting as an Altitudinal Visual Field Defect: A Rare Case

By Gursan Gunes Uygun, Sevcan Yildiz Balci, Hulya Tireli,

Brucellosis is a zoonotic disease with a wide range of ophthalmic manifestations, including optic neuritis. It is most commonly caused by the consumpt...


Malignant Peripheral Nerve Sheath Tumor of the Cervix: A Case Report

By Tiantian Zhang, Zishu Wang, Rui Wang, Xiao Wu, Menglin Zhao, Fang Su,

The occurrence of primary malignant peripheral neurilemmoma in the female cervix without neurofibromatosis type 1 is extremely rare. We herein report ...


SUPERIOR MESENTERIC ARTERY SYNDROME

By ASIF ALI AMIR ALI, Kanwal Hameed, Ali Nawaz, Imran Khan, Sughra Perveen,

We report a rare case of upper gastrointestinal obstruction diagnosed in a 15 years old boy presenting with a 6 months long history of recurrent abdom...


Management of Gastric Tumor Perforation with Conservative Treatment during Neoadjuvant Chemotherapy

By Emre Bozkurt, Sinan Omeroglu, Emir Capkinoglu, Onur Guven, Mehmet Mihmanli,

Perioperative chemotherapy provides advantage for gastric cancer patients in terms of survival. A 56-year male with a diagnosis of locally advanced ga...


Digital Necrosis Due to Septic Embolism: An Unseen Complication of Gangrenous Cholecystitis

By Nazmi ÖZER, Abdullah Sahin,

  Gangrenous cholecystitis is one of the most severe complications of cholelithiasis. It causes serious morbidity and mortality. The main pathology i...


Association Between Serum Carcino-Embryonic Antigen Levels And Micropapillary Bladder Cancer Metastasis in an Elderly Male

By Caner Ediz, Neslihan Kaya Terzi, Serkan Akan, Omer Yilmaz,

We herein present a case of a micropapillary variant of bladder cancer metastasizing to lymph nodes in an 87-year male with elevated serum carcinoembr...


Successful surgical removal of a huge hepatocellular carcinoma: a case report

By Wang Gu, Guoqing Long, Qili Hu, Zhong Tong,

Hepatocellular carcinoma (HCC) is the most common primary liver cancer. Hepatectomy and transcatheter arterial chemoembolization (TACE) are generally ...


Methotrexate-induced leukoencephalopathy, a rare but life-threatening toxicity

By Jahanzeb Ur Rehman, Fayaz Hussain, Qamar Un Nissa, Sayed Kamran Mahmood, Tariq Ghafoor,

Methotrexate (MTX), an anti-metabolite, is part of various chemotherapy regimens to treat Acute Lymphoblastic Leukemia (ALL) and certain Non-Hodgkin...


Fibrolipoma of Tongue: A rare entity

By Salima Mansoor Ali, Nausheen Yaqoob, Anila Haneef, Sunder Sham, Asif Ali Arain,

Lipomas are benign mesenchymal tumors that comprise almost one-half of all soft tissue tumors. Lipomas can occur at any site where fat cells are prese...


Acute Acalculous Cholecystitis due to EBV infection presenting as acute abdomen

By Gulhadiye Avcu,

Epstein-Barr Virus (EBV) is a herpes virus with a high seropositivity rate among adult population through out the world.  Primary EBV infection is us...


Anti-Leucine-Rich Glioma-Inactivated 1 Limbic Encephalitis: An Underrecognized Disease

By Danish Nabi, Mian Ayaz Ul Haq, Mehtab Alam, Saqib Ali, Shoaib Ismail, Amjad Iqbal,

Autoimmune limbic encephalitis is a rare autoimmune disease characterized by inflammation of the limbic system of the brain. The disease runs a sub-ac...


Paratesticular Solitary Fibrous Tumor Mimicking Cellular Angiofibroma: an unusual morphology and rare site

By Madiha Bilal Qureshi, Muhammad Usman, Qurratulain Chundriger, Nasir Uddin,

Solitary fibrous tumor (SFT) is a ubiquitous benign mesenchymal tumor of fibroblastic origin, which occurs most often in middle-aged adults. It usuall...


First documented case of pulmonary alveolar proteinosis with atopy presenting secondary to CSFR2B mutation

By Ayse Senay Sasihuseyinoglu, Dilek Dogruel, Arbil Avci, Gursu Kiyan,

Pulmonary alveolar proteinosis (PAP) is a rare lung disorder in which surfactant-derived lipoproteins accumulate excessively within pulmonary alveoli,...


Lafora body epilepsy: A challenging diagnosis

By Ali ZOHAIR Nomani, Haris Majid Rajput, Hanna Nomani,

Lafora body disease (LBD) is a progressive myoclonic genetic epilepsy syndrome characterized by the presence of Lafora inclusion bodies within neurons...


Takayasu arteritis with isolated headache and neck pain: A Case Report

By Doctor Nazia Arain, Dr Shamsuddin Shaikh, Jawad Ali,

Takayasu Arteritis (TA),  a  chronic inflammatory condition of the aorta and its major branches,  causes narrowing and ultimate occlusion of major ...


Primary Hepatic Sarcomatoid Carcinoma presenting with Dysphagia: a rare presentation

By Khadim Hussain Samajo, Zain Majid, Rajesh Mandhwani, Mohammad Mubarak, Nasir Hassan Luck,

A 50-year male presented with vomiting and dysphagia for 2 weeks. Laboratory workup showed a positive serology for hepatitis C and normal serum α-fet...


Giant sigmoidal lipoma protruding through anal canal and causing sigmoidorectal intussusception

By Ali Surmelioglu, Serhat Ozer,

Intussusception is a rare condition in adulthood and there exists an underlying pathological lesion in most cases. Colorectal lipoma is the second mos...


Sturge-Weber syndrome with bilateral fronto-parieto-temporal lobe atrophy and bilateral leptomeningeal angiomatosis: a rare case

By Dr Ashok Kumar,

Sturge-Weber Syndrome (SWS) is a phacomatosis characterized by a Port-Wine stains, leptomeningeal angiomatosis, and glaucoma. Leptomeningeal angiomato...


Coexistence of Colon Perforation And Congenital Lipodystrophy in A Young Adult: A Rare Entity

By Nihan Acar, Turan Acar, Beste Suataman, Neşe Ekinci, Fatma Tatar,

Lipodystrophy (LD) is an acquired or congenital rare condition consisting of hyperlipidaemia, glucose intolerance/ insulin resistance, and almost comp...


Central Pancreatectomy for Solid Pseudopapillary Tumour of Pancreas in A 13-Year Girl

By Abdul Wahab Dogar, Shamsuddin Zehri, Hasnain Abbas, Irfan Haider,

Solid Pseudopapillary Tumour (SPT) is a very rare tumour of pancreas.  A 13-year girl presented to us with the complaint of upper abdominal pain and...


Salvage for postpartum massive hemorrhage in a Jehovah’s Witness with intravenous iron therapy and cell saver system

By TUGBA SARAC SIVRIKOZ, Cigdem Kunt Isguder, Muhterem MELIS Canturk, Mukadder Orhan Sungur, Sevgi Kalayoglu Besisik,

Intraoperative cell salvage (ICS) system performs autologous transfusion by filtering and reinfusing the shed blood into corporeal circulation during ...


Salvage intrapartum splenectomy for the treatment of transfusion-refractory anemia in a ß-thalassemia intermedia patient

By Tugba Sarac Sivrikoz, Murat Ozbalak, Aykut Ozmen, Mustafa Tukenmez, Sevgi Kalayoglu Besisik,

Thalassemia intermedia (TI) patients may need transfusion during physiological stress conditions, such as pregnancy. We present a case of a female TI ...


Geminated Tooth on the Right Lower Second Molar with Buccal Skin Fistula: A case report

By Zao Chen, Lu Chen,

This case report describes a patient with buccal skin fistula caused by a geminated tooth on the mandibular second molar. By means of cone beam CT (CB...


Prepontine and Meckel's Cave Dermoid Cyst: MR and CT Findings With Literature Review

By Behice Kaniye YILMAZ, Nurdan Gocgun, Tuba Selcuk Can, Sevim Ozdemir, Rustu Turkay,

Dermoid cysts (DCs) are benign, congenital tumors that comprise 0.04-0.6% of all intracranial tumors. DC rupture is a rare complication and usually oc...


A Rare Case in Urology: Inflammatory Myofibroblastic Tumor

By Murat Akgül, Mehmet Fatih Sahin, Meltem Oznur, Aysegul Arslan, Cenk Yazici,

Inflammatory myofibroblastic tumor (IMT) is a soft tissue malignancy with a mixture of myofibroblastic spindle cells with hyalinized stroma and inflam...


Invasive and Non-invasive Ductal Carcinoma within Malignant Phyllodes Tumour with Axillary Lymph Node Metastases

By Osman ERDOGAN, Alper Parlakgumus, Zeynel Abidin Tas, Kemal Yener, Umit Turan,

Phyllodes tumours are uncommon breast neoplasms constituting 1-2% of breast malignancies. Metastasis is usually haematogenous, and axillary lymph node...


Changes in the Anterior Lens Epithelium and Basement Membrane in Pseudoexfoliation Syndrome Undergoing Surgery for Senile Cataracts: A Transmission Electron Microscopic Study

By Ozlem Dikmetas, Yasemin Kapucu, Aysegul Firat, Mustafa Fevzi Sargon, Sibel Kocabeyoglu,

Objective: To compare electron microscopic lens findings with and without pseudoexfoliation syndrome (XFS), in patients undergoing surgery for senile ...


Neurobrucellosis Presenting with features of demyelinating disorder in a pediatric patient: Case report

By Muhammad Saeed, Ahmed Al Bishri Al Bishri, Saleh Al Qahtani Al Qahtani, Ayed ABDULLAH Shati, Sanaa Gammaa, Abdul Qadir Saeed,

Brucellosis is an endemic disease in Saudi Arabia,  which can present with variable clinical manifestations. It is a zoonotic disease transmitted fro...


Spinal Muscular atrophy with Respiratory distress type 1. A Novel variant of IGHMBP2 gene

By Muhammad Saeed Saeed,

Spinal muscular atrophy (SMA) with respiratory distress type 1 (SMARD1) is an exceptionally rare type of SMA. It results from disintegration of alpha ...


Pancreatic transection in a 6-year old child following bicycle handlebar injury

By Geetanjali Sahariah Khound, Dibyajyoti Bora, Rekha Khaund Borkotoky, Siba Prosad Paul,

Bicycle handlebar injuries are the commonest cause of pancreatic trauma in children and adolescents, especially in males. Recognition of such injuries...


A Giant Esophageal Epiphrenic diverticulum causing dysphagia, fungal infection and aspiration pneumonia in an elderly patient

By Sabhita Shabir Shaikh, Raheela Khalid,

Esophageal epiphrenic diverticulum is a rare condition. We present a case of a 70-year male with no known co-morbidities who presented with dysphagia,...


The Fate of Coracoid Graft after Latarjet Procedure:Arthroscopic and Open Findings of Graft Union and Glenoid Remodelling

By Mohd Nizlan Mohd Nasir, Raymond Yeak Dieu Kiat, Ahmad Hisham Rashid,

Successful Latarjet procedures depend on many factors, including graft union and subsequent restoration of the glenoid surface. Coracoid graft union h...


Urachal Actinomycosis presenting with recurrent urinary tract infections in a middle-aged Woman: A Rare Case Report

By Basri Cakiroglu, Cevdet Kaya, Ramazan Gozukucuk, Suleyman Hilmi Aksoy, Lora Ates,

The urachal cyst, a remnant of allantois sac during embryogenesis, is a rare condition in adulthood. Urachus is an embryologic remnant degenerating af...


Diabetic myonecrosis; A vascular complication

By Daniyal Nadeem, Nanik Ram,

Diabetic myonecrosis is an unpublicized problem that can occur in patients having either type 1 or type 2 diabetes mellitus. It usually effects patien...


Successful pregnancy outcome in a lady with polyglandular autoimmune syndrome type II

By Munazzah Rafique, Devjani Das,

We report a case of a lady who had polyglandular autoimmune syndrome type II (Hypothyroidism, Addison’s Disease, Vitiligo) who completed a successfu...


A Rare Case of Post-pubertal Pure Yolk-sac Tumor Incidentally Diagnosed After Surgical Intervention for Fournier’s Gangrene

By Ahmet Asci, Hakan Bahadir Haberal, Fariba Amini, Deniz Ates Ozdemir, Ahmet Gudeloglu,

Testicular tumor is the most common solid malignancy in males between the ages of 15 and 35 years. Testicular tumors most commonly present with a pain...


A Case of Euglycemic Diabetic Ketoacidosis Due To Empagliflozin Use in A Patient With Type 1 Diabetes Mellitus

By Satilmis Bilgin, Tuba Taslamacioglu Duman, Ozge Kurtkulagi, Feyza Yilmaz, Gulali Aktas,

Euglycemic diabetic ketoacidosis is characterized by serum blood glucose <250 mg/dl, arterial blood pH <7.35 and the presence of ketones in urine or b...


Adoption of Digital Pathology in Developing Countries: From Benefits to Challenges

By Talat Zehra, Asma Shabbir,

Digital pathology and the use of artificial intelligence constitute undisputedly the future of modern pathology. The outcomes and benefits of whole sl...


Cystic Neutrophilic Granulomatous Mastitis: Case Series and Literature Review

By Qurat Ul Ain Zahid, Nausheen Yaqoob, Nausheen Feroz, Sheema Habib Hasan,

Granulomatous lobular mastitis (GLM) is an infrequent inflammatory breast disease, which can simulate malignancy on the basis of clinical and imaging ...


Posterior Fascicular Ventricular Tachycardia: A Rare Cause of Tachycardia

By Erdem Kurt, Rohat Ak, Suphi Bahadrl,

A 13-year male patient with a history of tachycardia attacks was diagnosed to have left posterior fascicular ventricular tachycardia (VT) according to...


An Unusual Laboratory Accident: Bromine Burn

By Hasan Basri Cetinkaya, Harun Gunes,

Bromine is a water-soluble, severely toxic element.  It leads to tissue injury by causing release of radical oxygen species from mucosal membranes. R...


Huge primary intermediate-grade myofibroblastic sarcoma in the retroperitoneum: a case report

By Huang Hong Jun, Wu Zhi Ming, Meng Xing Cheng, Chen Yong Liang, Han Qi,

Myofibroblastic sarcoma is exceedingly rare, with low-grade features in most cases, and rarely involves the retroperitoneum. The 2020 World Health Org...