Journal of the College of Physicians and Surgeons Pakistan
ISSN: 1022-386X (PRINT)
ISSN: 1681-7168 (ONLINE)
Effects of PCSK9 Inhibitors On Glucose Metabolism in Hyperlipidaemia Patients: A Meta-AnalysisBy Yujie Bai, Miao Hu, Jiayan Zhang, Ling Zhou, This review assessed the impacts of PCSK9 inhibitors on glucose metabolism in patients with dyslipidaemia. A comprehensive search was conducted using ... |
Sevoflurane Anaesthesia Increases the Risk of Perioperative Acute Kidney Injury than Propofol: A Meta-analysis of RCTsBy Mingjuan Li, Wenli You, Xiaosa Chi, Maomao Nie, Anmu Xie, Sevoflurane has been suggested to lower the incidence of acute kidney injury (AKI) after heart surgery compared to intravenous anaesthetics. However, ... |
Efficacy and Safety of Biologics and Immunosuppressants in Maintenance Therapy for Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Network Meta-AnalysisBy Liangdong Zhu, Minfang Guo, Siyu Gan, Keyu Li, Yong Fu, Xia Chen, Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a potentially life-threatening systemic autoimmune disease. This study aims ... |
Association Between C-Reactive Protein and Suicidal Ideation: A Large-Scale Cross-Sectional StudyBy In Cheol Hwang, Hong Yup Ahn, Yujin Park, Studies of C-reactive protein (CRP) levels and suicidal behaviours have shown inconsistent results previously. This study investigated the relationshi... |
The Effectiveness of Nicorandil in Heart Failure Patients: A Comprehensive Review and Meta-AnalysisBy Tongge Mu, Kaixuan Tang, Yan Sun, This meta-analysis aims to evaluate the effectiveness of nicorandil in treating heart failure by synthesizing evidence from diverse studies. This stud... |
Robotic Versus Laparoscopic Approaches to Distal Pancreatectomy: Quality Assessment of The Current EvidenceBy Attam Ullah Khan, Adan Khan, Arbab Danial, Pancreatic surgery, associated with technical difficulties and high complication rates, remains a challenge for surgeons. The laparoscopic approach ha... |
Outcome of Kangaroo Mother Care in Preterm And Low Birth Weight Newborn BabiesBy Dr Mehwish Asghar, Dr Naseer Ahmed, Dr Neelam Dileep, Dr Asghar Ali Kerio, Dr Laila Pirzado, Dr Mubashir Hussain, The objective of this study was to determine the outcomes of Kangaroo Mother Care (KMC) in preterm and low birth weight newborn babies. This prospecti... |
Abnormal Brain Function in Systemic Lupus Erythematosus: A Meta-Analysis of Resting-State Functional Magnetic Resonance ImagingBy Xi Sun, Dongmei Fu, Yuting Mao, Zuanfang Li, Yinghong Lin, Jiaqiu Lin, This meta-analysis investigated the neurophysiological underpinnings of systemic lupus erythematosus (SLE) by examining resting-state functional magne... |
Incisional Hernia Repair: Metanalysis on Laparoscopic and Open Surgical RepairBy Rosario Vecchio, Serena Scilletta, Eva Intagliata, Despite the benefits of laparoscopic surgery, routine laparoscopic treatment of incisional hernia remains controversial. The aim of this meta-analysis... |
Correlation of Peripheral Blood CD4/CD8 Ratio with Efficacy and prognosis in Patients with Non-Small Cell Lung Cancer Receiving PD-1/PD-L1 InhibitorsBy Qi-ming Zheng, Guo-xiang Li, Yuan-yuan Li, Ye-peng Wang, Min Zhang, Zhi-gang Sun, The aim of this study was to investigate the predictive role of peripheral blood CD4/CD8 ratio in patients with non-small cell lung cancer (NSCLC) tre... |
Outcomes of Auto Hematopoietic Stem Cell Transplant in Lymphomas, a Single Centre StudyBy Dr Irsa Hidayat, Dr Mehreen Ali Khan, Dr Munazza Nabi Awan, Dr Awais Siddiq, Dr Noor Shamim, Dr Hashim Khan, Objective: To determine the outcomes of auto hematopoietic stem cell transplant in lymphoma patients in terms of overall survival, disease free surviv... |
Correlation of HER2 Expression in Gastric Carcinoma with Clinicopathological Parameters in the Omani PopulationBy ASIM QURESHI, Hana Al Julandana, Sara Al Barkhati, Ahmed Al Ghaithi, Asem Shalaby, This retrospective study was conducted to determine the relation between Her2 expression and the clinicopathological and prognostic characteristics of... |
The Association Between Facial Aging and Bone Mineral Density: A Mendelian Randomization StudyBy Yabo Wang, Chao Zhen, Ziyu Wang, Lu Zhang, Yunzhen Chen, This article aimed to assess the causative association between facial aging and bone mineral density (BMD) using Mendelian randomization (MR). In this... |
Outcome of Hematopoietic Stem Cell Transplant in Beta-Thalassemia MajorBy Hashim Khan, Tariq Ghafoor, Nighat Shahbaz, Tariq Azam Khattak, Uzma Rahim, Munazza Nabi Awan, Objective: To determine the outcome of Hematopoietic stem transplant (HSCT) in beta-thalassemia major patients. Study Design: Descriptive Study. ... |
Comparison of Pulmonary Index Score after Treatment with Salbutamol through Nebulizers Vs Metered – Dose Inhalers with Spacer Device for Treatment of Childhood WheezeBy Arooj Khan, Shaista Azeem Khan, Syed Mohsin Ali Shah, Faizan Sadiq, Abdul Khaliq, Shahana Nisar, The aim of this study was to compare the mean pulmonary index score after salbutamol delivery through nebulizers and metered-dose inhalers with spacer... |
Oxidative Balance Scores In Cancer Survivors: A Nationwide Cross-Sectional StudyBy Jaehyuck Lee, In Cheol Hwang, Hong Yup Ahn, Although some studies have investigated the relationship between oxidative imbalance and adverse outcomes, there is a lack of data on oxidative balanc... |
Association Between Mental Health and Metabolic Dysfunction–Associated Fatty Liver DiseaseBy Ji Hyeon Park, Yoo Jeong Lee, In Cheol Hwang, Hong Yup Ahn, Depression has recently been suggested as a novel predisposing factor for metabolic dysfunction–associated fatty liver disease (MAFLD) among US adul... |
Glomerular Filtration Rate By Gamma Camera Based Method: A Single Centre Interobserver Agreement StudyBy Rebecca Sharoon, Zaigham Salim Dar, Muhammad Atif, Zeeshan Sikandar, Raana Fatima, The objective of this study was to determine interobserver agreement in calculation of glomerular filtration rate by gamma camera-based method. It was... |
Role of Intralesional Vitamin D3 in The Treatment of CutaneouswartsBy Dr Sabahat, Seemab Khaan, Noor Us Sabah, Objective: To determine the effect of Intralesional Vitamin D3 injection in the treatment of cutaneous warts. Study design: Quasi experimental stud... |
Association between Preoperative Expectations and Postoperative Satisfaction in Patients Undergoing Arthroscopic Rotator Cuff RepairBy Qilong Jiang, Yang Liu, Zhi Zhao, Yu Chen, Yu Deng, The aim of this study was to determine the association between preoperative expectations (PE) and postoperative satisfaction for patients undergoing a... |
Impact of Hands-on Cadaveric Dissection Courses on the Improvement of Surgical Skills of Ear, Nose and Throat Surgeon; A Survey from the Consultants and Postgraduate TraineesBy Saleh Khurshied, Altaf Hussain, Mujahid Raza, Nawal Khurshid, Maesum Ali, Mehrunnisa Nawaz, A cross-sectional observational study at Pakistan Institute of Medical Sciences, PIMS Islamabad from April 2023 to May 2024 to determine the impact of... |
Comparison of clinical outcomes of Hand-Assisted Retroperitoneoscopic with the Hand-Assisted Laparoscopic Donor Nephrectomy in Healthy Kidney DonorsBy Umar Farooq, Asad Bashir, Nasrum Minallah, Fiaz Ahmad Touqeer, Zia Ul Haq Akram, Ali Asad, Objective: To compare the outcomes of Hand-Assisted Laparoscopic (HALS) and Hand-Assisted Retroperitoneoscopic (HARS) donor nephrectomy procedures. ... |
Integration of Digital Modality in Virtual Classroom Enhances Nursing Students’ Inclusiveness in Learning: A Game Based ApproachBy Sanam Hanif, Rabab Vadivala, COVID-19 and virtual learning were transformative changes for educators and students in nursing education. This rapid shift necessitated educators to ... |
Clinical Outcomes and Long-Term Effects of Consolidative Radiotherapy in Paediatric Hodgkin's LymphomaBy Syed Muhammad Jawad Zaidi, Rabia Muhammad Wali, Naila Inayat, Sadia Anjum, Objective: To evaluate the long-term effects and disease outcomes of consolidative radiotherapy in paediatric Hodgkin’s lymphoma (PHL). Study Des... |
MALDI-TOF MS Application in M Protein Detection and Its Associations with Clinical Laboratory Findings in GeriatricsBy Jing Cheng, Yuying Zhang, Mingjie Cao, Yun Sun, Xiaomin Lv, Haiya Wang, Currently, the methods used to detect M protein such as SPEP (serum M-protein electrophoresis), IFE (immunofixation electrophoresis) and sFLC (serum f... |
Frequency of Disease Subsets and Spectrum of Organ Involvement and Interstitial Lung Disease Patterns in Patients of Systemic Sclerosis in Pakistani PopulationBy UMBREEN ARSHAD, Muhammad Ahmed Saeed, Muhammad Rafaqat Hameed, Maryam Aamer, Shamas U Din, Hafiz Yasir Qamar, Objective: ILD to assess frequency of disease subsets and the spectrum of organ involvement, particularly focusing on interstitial lung disease (ILD) ... |
Musculoskeletal Ultrasound in the Diagnosis and Interventional Management of Common Pain Disorders - Analysis from a Physiatry Pain ClinicBy SARAH RAZAQ, Muhammad Aleem Arshad, Waseem Iqbal, Objective: To determine the practical applications of musculoskeletal ultrasound (MSK US) in the precise diagnosis and optimal interventional manageme... |
Comparison of the Combination of Interscalene Block and Superficial Cervical Block Anaesthesia with Interscalene Block Anaesthesia in Shoulder Surgery OperationsBy Abdulhakim Şengel, Selcuk Secilmis, Evren Buyukfirat, Nuray Altay, Veysi Yazar, Mehmet Baki Bilsel, Objective: To compare shoulder surgery patients who received interscalene block and superficial cervical block anaesthesia with those who received onl... |
Balancing Benefits and Risks of the Use of Cage in Lumbar Spondylolisthesis Surgery: A meta-analysisBy Yunpeng Mao, Feng Yao, Chao Xu, Xinlin Wu, Yuhao Yang, Fuyong Zhang, Lumbar spondylolisthesis is a prevalent spinal disorder for which the primary treatment approach involves surgical intervention, including reduction, ... |
Effect of the COVID-19 Pandemic on Anaesthetic Workload at a Tertiary Care Hospital in PakistanBy Aliya Ahmed, Azmeena Nizar, Gauhar Afshan, Objective: To compare the anaesthetic workload during the COVID-19 pandemic with the workload immediately before and two years after the pandemic at ... |
Factors Influencing Glycemic Control in Adolescents with Type 1 Diabetics: Cross-Sectional Analysis of Individual and Parental FactorsBy Fozia Memon, Muzna Arif, Maryam Haider, Muhammad Farrukh Qazi, Imran Nisar, Khadija Nuzhat Humayun, Objective: To identify modifiable risk factors that influence glycaemic control in type I Diabetes adolescents. Study Design: Cross-sectional, anal... |
The Efficacy of Topical Hyaluronic Acid 0.2% in the Management of Symptomatic Oral Lichen PlanusBy Saadiya Siddiqui, Ayesha Chatta, Faria Altaf, The aim of this study was to evaluate the efficacy of 0.2% topical hyaluronic acid in management of symptomatic oral lichen planus (OLP). This prospec... |
Evaluating Medical Educators Practices: Core Competencies and Entrustable Professional Activities (EPAs) for Healthcare Professional EducatorsBy Khadija Farrukh Warraich, The objective of the research was to evaluate core competencies and entrustable professional activities (EPAs) for healthcare professional educators s... |
Comprehensive Evaluation of Peripheral Blood Count Parameters in Donor Deferral Practices: Its Utility as a Quality Control Tool in Blood Banking ServicesBy Helen MARY Robert, Zunairah Mughal, Noman Anjum Rana, Intzar Ali, Sumaira Ilyas, Ayesha WAHID Mian, This study assessed the role of peripheral blood counts in donor deferral and its utility as a quality control measure in blood banking. Conducted ret... |
Predictive Factors for Multiple Sessions of Retrograde Intrarenal Surgery to Achieve Stone-Free StatusBy Volkan Selmi, Mehmet Caniklioglu, Sercan Sari, Levent Isikay, Objective: To investigate the potential predictive factors of requiring multiple sessions of retrograde intrarenal surgery (RIRS) to achieve stone-fre... |
The Effectiveness of Team-Based Learning Compared with Lecture-Based Learning in Clinical Medicine: A Meta-AnalysisBy Bingrui Lu, Shu-hong Huang, Xu-ying Shi, Guo-xiang Li, Qing Yin, Zhi-gang Sun, A comprehensive comparison and evaluation of the effects of Team-based learning (TBL) and Lecture-based learning (LBL) on clinical medical education w... |
Early versus Late Stoma Reversal in Children Presenting with Acute AbdomenBy Abdullah Khan, Muhammad Bilal Mirza, Nabila Talat, Objective: To determine the morbidity e.g., anastomotic leakage and wound infections, in children enduring early (same admission) versus late (routine... |
Artificial Intelligence in Medical EducationBy Muhammad Farooq, Ambreen Usmani, Objective: To explore the understanding of medical students regarding integration of AI in medical education. Study Design: Mixed methods explanato... |
Comparison of Dexmedetomidine vs Propofol for Magnetic Resonance Imaging in Children: A Meta-AnalysisBy Wei Yang, Mingjun Zhu, Jun Xu, Yueyong Wang, Pediatric magnetic resonance imaging (MRI) allows visualization of internal structures in children without ionizing radiation, often requiring sedatio... |
Anti MOG Antibody Associated Disorders in PakistanBy 1. Tahira Mohammad, Arsalan Ahmad, Tahir Aziz Ahmed, Objective: To present clinicopathological features and treatment outcomes of patients who tested positive for anti-myelin oligodendrocyte glycoprotein... |
Efficacy and Safety of Antifungal Drugs in Invasive Aspergillosis: A Network Meta-AnalysisBy Liangdong Zhu, Xun Yang, Keyu Li, Xiaolin Li, Xia Chen, A frequentist network meta-analysis was conducted to assess the efficacy and safety of voriconazole, posaconazole, isavuconazole, amphotericin B deoxy... |
Development and validation of a tool to evaluate dental residents’ understanding and satisfaction with their post-graduate summative assessment.By Syed Murtaza Raza Kazmi, Fakeha Azhar Syed, Tabassum Zehra, Students’ comprehension of the assessment process is critical for a successful evaluation. The authors at the Aga Khan University Hospital, develope... |
Translational Biomedical Research: Challenges and Solutions of Using Animal ModelsBy Shahid Akhund, In translational research utilization of laboratory animal models contribute significantly to the understanding of human diseases, diagnostics, and th... |
Gender Differences in Cigarette Smokers' Exhaled Carbon Monoxide and Nicotine Dependency LevelsBy İzzet Fidancı, Cansu Alici Yilmaz, Hilal Aksoy, Duygu Ayhan Baser, The purpose of this study was to determine whether smoking behaviour, exhaled carbon monoxide (CO) levels, and addiction status differ between male an... |
Adherence to Practice Guidelines for Postoperative Epidural AnalgesiaBy Sami Ur Rehman, Muhammad Malik, Muhammad Adeel Sabir, Arshad Taqi, Abdul Rehman, Maryam Inayat, Objective: To evaluate the adherence to practice guidelines for epidural insertion along with the drugs used for postoperative analgesia and the incid... |
Efficacy and safety of memantine augmentation treatment for obsessive–compulsive disorder: meta-analysisBy Wenxuan Zhang, Yuhan Zhang, Enyan Yu, Obsessive–compulsive disorder (OCD) is a highly disabling mental illness characterised by repetitive thoughts and behaviours that disrupt daily life... |
Complete Remission in BCLC stage C Hepatocellular Carcinoma Treated with HAIC Combined with PD1 Inhibitors and Anti-angiogenic TherapyBy Shitao Lu, Yapan Guo, Wencong Feng, Jun Yang, Yu Yin, Zhi Li, Hepatocellular carcinoma (HCC) at BCLC stage C poses substantial therapeutic challenges and is typically associated with a poor survival prognosis. Th... |
An Overview of Generative Artificial Intelligence in Medical EducationBy Shilu Wang, Rongqing Geng, Rongguang Xu, The application of Generative artificial intelligence (GAI) in medical education and practice has garnered increasing attention, particularly its sign... |
OCCURRENCE OF PARAFUNCTIONAL HABITS IN ADULTS WITH AND WITHOUT TEMPOROMANDIBULAR DISORDERBy Ateeqa Younis, Nadia Zaib, Maira Tafzeel, Muqaddas Zafar, Hajra Habiba, Sameen Aamir, The objective of the study was to determine the occurrence of parafunctional habits in adults with and without temporomandibular disorder. It was a cr... |
The Educational Application of Teacher-made Mind Maps on StudentsBy Jin-lan Zhou, Shan-qin Wang, Kai-deng Hong, Ren-jiao Cai, Jing Chen, Xing-Wei Zhe, This study's purpose was to look into the potential educational applications of teacher-made mind maps on the students. This is a single-group wit... |
Efficacy of Sofosbuvir and Daclatasvir Combination Treatment in Chronic Hepatitis C in Patients Among Haemodialysis PatientsBy Sindhya Memon, Pooran Mal, Joti Seetlani, Aimen Yousuf, Shahnaz Rahimoon, Neelam Memon, The aim of this study was to determine the effectiveness of Sofosbuvir and Daclatasvir (SOF/DCV) combination treatment in hemodialysis patients with c... |
Efficacy of Repeated Low-level Red Light in the Prevention and Control of Myopia among Children and AdolescentsBy Xue Zhang, Zirui Liu, Di Zhang, Zhuang Xiong, Objective: To evaluate the efficacy of repeated low-intensity red light (RLRL), orthokeratology lenses, and defocus spectacle lenses in controlling ax... |
Mixed Phenotypic Acute Leukaemia: Bridging the Gap Between Myeloid and Lymphoid LineagesBy Muhammad Zain Arshad, Muhammad Hussain, Muhammad Omair Riaz, Mustajab Alam, Muhammad Aftab Hassan, Maymoona Sohail, Objective: To characterize mixed phenotypic acute leukaemia (MPAL) by flowcytometric immunophenotyping in local population of Pakistan. Study design:... |
Neurological Mysteries of Behçet’s Disease through Rheumatologist's EyesBy Dilara Bulut Gokten, Ridvan Mercan, In this study, the aim was to describe the frequency, the locations and neurological symptoms in Behcet’s patients to contribute to the understandin... |
An insight into Chronic Laparoscopic Port Site Infections: A Systematic reviewBy Muhammad Tahir Ghani, Ibad Ur Rehman, Nain Sukh Dr, Burhan Tariq, Arif Khurshid, M Ali Aadwani, Chronic laparoscopic port site infections (PSI) are known to be caused by non-tuberculous mycobacterium (NTM). The aim of this systematic review was t... |
Rivaroxaban versus enoxaparin for the prevention of venous thromboembolism and wound complications after total knee arthroplasty:A systematic review and meta-analysisBy Shasha He, Xiangbao Yin, Yingqi Xu, Zhiwei Zhong, A systematic review was conducted to compare rivaroxaban and enoxaparin in preventing venous thromboembolism (VTE) and wound complications after total... |
Electrical Impedance Tomography-Guided Positive End-Expiratory Pressure Titration in Acute Respiratory Distress Syndrome: A Meta-AnalysisBy Mumu Fan, Yunnan Hu, Peirong Zhang, This study explored the effectiveness of an electrical impedance tomography (EIT)-based positive end-expiratory pressure (PEEP) titration strategy com... |
Comparison of Success Rate of Direct versus Indirect Sinus Lifting Techniques for Vertical Bone Augmentation in Patients with Maxillary Dental ImplantsBy Syed Ammar Yasir, Muhammad Ishaq, Sameen Naweed, Syed Junaid Hussain Bukhari, Tariq Mahmood, Muhammad Arham, Objective: To compare direct and Indirect sinus lifting techniques in patients getting implants in maxillary molar region for parameters like post-ope... |