JCPSP | Journal of College of Physicians and Surgeons Pakistan

Epub Ahead of Print


Short Communication Complete Remission in BCLC stage C Hepatocellular Carcinoma Treated with HAIC Combined with PD1 Inhibitors and Anti-angiogenic Therapy By Shitao Lu, Yapan Guo, Wencong Feng, Jun Yang, Yu Yin, Zhi Li, Hepatocellular carcinoma (HCC) at BCLC stage C poses substantial therapeutic challenges and is typically associated with a poor survival prognosis. Th...
Short Communication The Educational Application of Teacher-made Mind Maps on Students By Jin-lan Zhou, Shan-qin Wang, Kai-deng Hong, Ren-jiao Cai, Jing Chen, Xing-Wei Zhe, This study's purpose was to look into the potential educational applications of teacher-made mind maps on the students. This is a single-group wit...
Short Communication Efficacy of Sofosbuvir and Daclatasvir Combination Treatment in Chronic Hepatitis C in Patients Among Haemodialysis Patients By Sindhya Memon, Pooran Mal, Joti Seetlani, Aimen Yousuf, Shahnaz Rahimoon, Neelam Memon, The aim of this study was to determine the effectiveness of Sofosbuvir and Daclatasvir (SOF/DCV) combination treatment in hemodialysis patients with c...
Systematic Review Article Electrical Impedance Tomography-Guided Positive End-Expiratory Pressure Titration in Acute Respiratory Distress Syndrome: A Meta-Analysis By Mumu Fan, Yunnan Hu, Peirong Zhang, This study explored the effectiveness of an electrical impedance tomography (EIT)-based positive end-expiratory pressure (PEEP) titration strategy com...
Short Communication Medical students’ deaths by suicide in Pakistan: An alarming trend and a Call for Action By Sania Mumtaz Tahir, Muhammed Omer, Ahmad Nawaz, Nazish Imran, Suicide among medical students is a serious issue. To understand the pattern and risk factors of medical students’ deaths by suicide, a Google searc...
Short Communication Imaging features and clinicopathology of adenoid cystic carcinoma of the head and neck By Wanyi Shao, Yingyu Dai, Shan Huang, Yonghao Liu, Adenoid cystic carcinoma (Adenoid cystic carcinoma, ACC) is relatively rare in head and neck tumours, and the early imaging features are not specific,...
Short Communication Nicotine dependence as a prognostic factor for glycemic control in non-diabetic smokers: A nationwide Korean survey By Ji Hyeon Park, Yoo Jeong Lee, In Cheol Hwang, Hong Yup Ahn, This study examined the independent relationship between nicotine dependence and glycaemic indices among non-diabetic smokers. Data of 672 non-diabeti...
Short Communication Beyond the waves: Assessment of the clinical appropriateness of electroencephalography referrals in neurological practice By Noor Fatima, Safia Bano, Ahmad Nawaz, Muhammad Imran Malik, Muhammad Usman Choudhary, Ahsan Numan, This cross-sectional study evaluated the appropriateness of EEG referrals at the Department of Neurology, Mayo Hospital and King Edward Medical Univer...
Short Communication Clinical Utility of Ultrasound-Guided Midline Catheters in Cardiovascular Intensive Care Unit By Fen Xu, Tao Xiang, Liang Hui Zhang, Ling Liang, Feng Liu, Xiongfei Xu, This observational study evaluated the clinical utility of ultrasound-guided midline catheters (MCs) for cardiovascular medicine delivery in a cardiov...
Short Communication Simulation based training for Limberg Flap Technique for Pilonidal Sinus through task trainer: Strategy to enhance surgical skills. By Dr. Rubab Nafees, Dr Rabia Aftab, Dr. Komal Faheem, Dr. Madeeha Shahid, Dr Aun Ali, Intergluteal pilonidal sinus is a common disease of adults especially males and is related with high morbidity. The rhomboid flap reconstruction for p...
Short Communication Ventilator Associated Pneumonia as Biggest Challenge: Incidence, Risk Factors, Prevention and Mortality Rate By Sami Ur Rehman, Unaiza Saeed, This cross-sectional study was done in Surgical ICU of Doctors Hospital and Medical Centre, Lahore, Pakistan from 1st January to 31st December 2023, t...
Short Communication Empowering health care professionals with the innovative ‘five tips’ approach. By Dr Sara Shakil, Dr. Rabia Aftab, Dr. Azam Afzal, Dr. Shazia Babar, Muhammad Tariq, In the era of information bombardment, it is mandatory to adopt the ability to receive new information and apply it in respective context. Healthcare ...
Short Communication Non-Communicable Diseases and Their Implications in Pregnant Women- Results from a Cross-Sectional Study in Pakistan By Dr Naima Shirazi, Dr Huda Sarwar, Afifa Tanweer, Non communicable diseases (NCDs) during pregnancy can have detrimental outcomes for the mother-child pair. An analytical cross-sectional study was con...
Clinical Practice Article Comparison of Classical Blood Cardioplegia and Modified Del Nido Cardioplegia on Postoperative Serum Lactate, and Extubation Times. By Burak Tamtekin, Güler Gülsen ERSOY, Objective: This study aimed to compare the effects of intermittent classical blood cardioplegia and single-dose modified Del Nido cardioplegia in coro...
Meta-Analyses Role of n-acetylcysteine in the prophylaxis against contrast induced nephropathy: A meta-analysis By BABAR RAFIQUE, Abdul Rehman Arshad, Sohail Sabir, Umair Ijaz, Obaid Ur Rahman, This study aimed to determine the effect of n-acetylcysteine in preventing contrast-induced nephropathy. Literature search was carried out on PubMed a...
Clinical Practice Article EVALUATION OF TEMPOROMANDIBULAR JOINT BONE DEGENERATIONS USING CONE BEAM COMPUTED TOMOGRAPHY in KENNEDY CLASS I and CLASS II PARTIALLY EDENTULOUS PATIENTS By Hakan Yulek, Gaye Keser, Filiz Namdar Pekiner, Suay Yağmur ünal, Objective: To assess temporomandibular joint (TMJ) osseous degenerations in Kennedy Class I and II partially edentulous patients using cone beam compu...
Short Communication Bleomycin-lipiodol emulsion combined with polyvinyl alcohol particles in the treatment of focal nodular hyperplasia of the liver: initial experience and literature review By Yan Wang, Wei-hao Zhang, Yong-fei Guo, Zhi-gang Tian, Mao Yang, Tong-guo Si, The purpose of this study was to explore the feasibility, effectiveness and safety of bleomycin-lipiodol emulsion combined with polyvinyl alcohol part...
Systematic Review Article A COMPARATIVE ANALYSIS OF MINIMALLY INVASIVE SURGICAL METHODS IN ESOPHAGECTOMY: A REVIEW STUDY. By Ifeanyi Christian Onyebuchi, Shaojin Zhu, You Qi, Guangjie Hou, Ifeanyi Christian Onyebuchi, This study compared the clinical efficacy and practicality of inflatable transcervical mediastinoscopic esophagectomy (TIME) versus minimally invasive...
Clinical Audit Is the classification of Ventilator-Associated Pneumonia as early and late-onset useful?: A comparison of microbial profile, antibiotic susceptibility and mortality By Sami Ur Rehman, Unaiza Saeed, Hussnain Bin Saeed, Saran Ghani, Arshad Taqi, Objective: To determine the microbial profile, antibiotic susceptibility, and mortality rates of early vs late-onset ventilator-associated pneumonia (...
Letter to the Editor Uncinate Processes Inner Margins Guide Quick and Mid-line Placement of Multilevel Plate on Cervical Vertebra with Severe Osteophyte and Technique Notes By Jingyun Wang, Fei Tan, Wei Xie, Qilin Lu, A 60-year male patient diagnosed with cervical spondylotic myelopathy and dysphagia had a prior history of diffuse idiopathic skeletal hyperostosis (D...
Meta-Analyses Low-Dose Tamoxifen for Breast Noninvasive Disease: A Meta-Analysis By Na Wang, Li Li Gong, Gang Hu, Mei Chun Ye, Tamoxifen is a classic endocrine therapy for breast cancer, but conventional doses of tamoxifen have serious side effects. Hence, it is crucial to pri...
Short Communication Palliative care in the Emergency Department: A step in the right direction By Sarah Afzal Kothari, Muhammad Atif Waqar, Shahan Waheed, Palliative care, as defined by the World Health Organization (WHO), focuses on improving the quality of life for patients facing life-limiting illness...
Viewpoint Dedicated Brain Injury Rehabilitation Units need in Pakistan By Muhammad Tawab Khalil, Sarah Razaq, MUSAB BIN NOOR, Fahim Anwar, Brain injuries are an increasing healthcare problem in Pakistan. Despite the growing burden of head injuries, there are few specialized brain injury...
Clinical Practice Article THE MODIFIED FRAILTY INDEX-5 AS A PREDICTOR OF POSTOPERATIVE COMPLICATIONS IN PATIENTS UNDERGOING RADICAL CYSTECTOMY By Erdinc Dincer, Orkunt Ozkaptan, Cengiz Canakci, Osman Murat Ipek, Alper Coskun, Utku Can, Objective: To evaluate the predictive value of the modified frailty index (mFI-5) for postoperative complications in patients undergoing radical cyste...
Clinical Practice Article Influencing factors and predictive model construction for lower extremity deep vein thrombosis after total knee arthroplasty By Zhongshan Gui, Beiyue Wang, Xiaoqiang Li, Objective: To identify the risk factors for deep vein thrombosis (DVT) following total knee arthroplasty (TKA) and develop a predictive nomogram model...
Viewpoint Toward Connected Care: Why Pakistan Needs Integrated Electronic Health Records By WAQAS AHMED KHAN, Pakistan’s healthcare system remains largely fragmented and paper-based, despite global momentum toward integrated, digital health models. This view...
Clinical Practice Article A DEEP LEARNING APPROACH TO DETECTION OF ORAL LEUKOPLAKIA LESIONS FROM INTRA ORAL PATIENT IMAGES USING FOUR DIFFERENT ALGORITHMS: A PRELIMINARY RETROSPECTIVE STUDY By Gaye Keser, Hakan Yulek, Filiz Namdar Pekiner, Objective: To assess the effectiveness of deep learning-based diagnostic software in identifying oral leukoplakia lesions from intraoral patient photo...
Clinical Practice Article A New Duodenum Traction Technique in Laparoscopic Treatment of Duodenal Obstruction in Neonates By Shan Zeng, Peng Zhang, Bin Zhong, Fang Shu, Baojian Liao, Shuqing Wu, Objective: To evaluate the effectiveness and safety of duodenum suspension in laparoscopic treatment of congenital duodenal obstruction. Study Design...
Clinical Practice Article Antibiotic and Microbiological Profiles in Hidradenitis Suppurativai By Dilek Menteşoglu, Selda Pelin Kartal, Objective: To investigate the results of swab cultures obtained from lesions of patients with hidradenitis suppurativa (HS) and their antibiotic resis...
Short Communication Symptoms, Triggers and Prodromes of Hereditary Angioedema in Pakistani Population By Muhammad Hussain, Muhammad Omair Riaz, Mustajab Alam, Hamid Nawaz Tipu, Muhammad Aftab Hassan, This cross-sectional observational study, conducted from September 2021 to December 2024 at the Department of Immunology, Armed Forces Institute of Pa...
Short Communication Development of the Kyphosis Cardiopulmonary Resuscitation (K-CPR) Technique in Patients with Spinal Mobility Restriction Due to Ankylosing Spondylitis By Hasan Sultanoğlu, Tuba Erdem Sultanoğlu, Patients with ankylosing spondylitis (AS) often present with spinal rigidity and kyphotic deformity, which may hinder conventional cardiopulmonary res...
Clinical Practice Article Relationship between the Atherogenic Index of Plasma and Glycated Haemoglobin A1c, Serum Uric Acid and Homocysteine in Type II Diabetes and Acute Stroke By Jingxuan Ma, Yinong Cui, Xi Yang, Objective: To examine the association between the atherogenic index of plasma (AIP) and glycated haemoglobin A1c (HbA1c), serum uric acid (SUA) and ho...
Commentary Cutaneous Histoplasmosis in HIV Patients: Brief Review By Maria Khan, SABA KHAN, Shifa Basharat, Due to advancements in diagnostics and worldwide HIV trends, histoplasmosis—a fungal infection caused by Histoplasma capsulatum—is spreading more...
Clinical Practice Article Clinical Presentation and Outcome of Patients Undergoing Surgery for Thyroid Cancer By Muhammad Moiz Ullah Khan, Iqbal Hussain Udaipurwala, Shahzad Maqbool, Asif Alam Gul, Muhammad Fahad Wasim, Fatima Siddiqui, Objective: To determine the clinical presentation, subtypes, and surgical outcomes of patients undergoing thyroid cancer surgery at a tertiary care ho...
Meta-Analyses GnRH Agonists and Antagonists in IVF/ICSI Cycles of PCOS Women: A Network Meta-Analysis By Huicong Yuan, Jiahui Zheng, Hio Tong Wong, Jianping Zhang, This study aimed to Computer searches were conducted in PubMed, Web of Science, Embase, Cochrane Library, CNKI, VIP, Wanfang, and CBM databases. Liter...
Viewpoint Gamifying Neurology: Lessons from The NExCARD Experience in Emergency Medicine Training By Shahan Waheed, Rida Jawed, Neurological emergencies are among the most time-sensitive and high-stakes presentations in emergency department yet they often remain underrepresente...
Clinical Practice Article Diagnostic Odyssey of CT Cystography in Unravelling Traumatic Bladder Injuries By Saba Imtiaz, Saima Ameer, Smeera Siddique, Muhammad Tahir Khan, Muhammad Kaleem, Mishal Waheed Butt, Objective: To evaluate the efficacy of CT cystography (CTC) in detecting bladder injuries following blunt pelvic trauma. Study design: Case series P...
Commentary Significance of Herbs in Dental World By Ihtesham Ul Haq, Waqar Un Nisa, Herbs have been historically used in the field of dentistry. For instance, peppermint oil and clove oil have been used for alleviating toothache by sa...
Commentary Significance of Herbs in Dental World By Ihtesham Ul Haq, Waqar Un Nisa, Herbs have been historically used in the field of dentistry. For instance, peppermint oil and clove oil have been used for alleviating toothache by sa...
Commentary Significance of Herbs in Dental World By Ihtesham Ul Haq, Waqar Un Nisa, Herbs have been historically used in the field of dentistry. For instance, peppermint oil and clove oil have been used for alleviating toothache by sa...
Meta-Analyses Radiotherapy-Chemotherapy Combinations in Locally Advanced Head and Neck Squamous Cell Carcinoma By Yi Quan Chen, Haijun Wu, This network meta-analysis (NMA) evaluated the efficacy and safety of radiotherapy combined with various therapeutic strategies in locally advanced he...
Meta-Analyses Comparative Efficacy of Conventional Milligan-Morgan and Ferguson Hemorrhoidectomy versus Diode Laser Hemorrhoidoplasty for Symptomatic Hemorrhoids: A Meta-Analysis based on RCT By Chaoyang Wang, Yihang Liu, Ziqian Wang, Bing Li, Yiwei Cao, Li Zheng, This meta-analysis compared the efficacy and safety of Diode Laser haemorrhoidoplasty (DLH) with traditional hemorrhoidectomy techniques, namely Milli...
Viewpoint The Urgent Need for AI- guidelines and framework for Medical Education and Research in Pakistan By Dr Fareeha Farooq, Dr Farooq Azam Rathore, The public release of ChatGPT in November 2022 and the rapid adoption of artificial intelligence (AI) tools have significantly influenced medical educ...
Short Article Efficacy of Topical 5–Fluorouracil Combined with Microneedling in the Treatment of Stable Vitiligo By Narmeen Mohammed Baher Abdulqader, Dindar Sharif Qurtas, Barzan Khalid Sharaf, Objective: To examine the effectiveness of topical 5-fluorouracil combined with microneedling in treating stable vitiligo. Study Design: Clinical pro...
Clinical Practice Article Assessment of Acetabular Fractures Fixation with Modified Harris Hip Score Regarding Clinical and Functional Outcomes By Syed Akmal Sultan, RUFINA ALI, Rahila Kanwal, Malik Amna Khatoon, Asif Ali, Objective: To assess the clinical and functional outcomes of acetabular fracture fixation at a 2-year follow-up using the modified Harris Hip score as...
Short Communication HCV Seropositivity Versus Care Non-compliance in Shenzhen Blood Donors By Yizhong Liu, Chenghui Huang, Yingkun Wang, Caiyue Fang, Jie Zhao, Sheng Zhang, This retrospective cross-sectional analysis assessed hepatitis C virus (HCV) prevalence, demographics, and post-diagnosis management among 220,990 vol...
Meta-Analyses Effects of Ulinastatin and Tranexamic Acid in Cardiac Surgery: A Systematic Review and Meta-Analysis By Xinyu Zhang, Hongqi Lin, Hongdang Xu, Yuntai Yao, Evidence suggests that both tranexamic acid (TXA) and ulinastatin (ULI) possess anti-inflammatory and blood-conserving properties. This study aimed to...
Short Communication Factors Predicting Cognitive Dysfunction End Stage Renal Disease By Saman Shuja Khan, Abdul Rehman Arshad, Muhammad Iqbal, Nushra Maqsood, This observational study probed into different factors potentially associated with cognitive impairment in patients aged 40 to 80 years on maintenance...
Short Communication A Comprehensive Assessment of Acute Stroke Care: Delays, Treatment Patterns, and Barriers to Timely Intervention By Saba Zaidi, Moomal Zoya, Mahzareen Ishrat, Sidra Jabeen, Ayesha Abdul Samad, The aim of the study was to evaluate the delays in emergency department arrivals of stroke patients and understand the demographics and factors leadin...
Meta-Analyses A Systematic Reviews and Meta Analyses of Liquid Biopsy Based Multimodal Approach for the Diagnosis of Pulmonary Nodules By Cao Ren Shuang, Tian JIAO Huang, Zhi Heng Lin, Fan Yang, Fei Liu, Feng Gao, Liquid biopsies demonstrate clinical utility as a non-invasive tool for discriminating malignant tumours from benign pulmonary nodules, as evidenced b...
Viewpoint The Paradox of a Pandemic Stalled by an Empty Sting By Moiz Ahmed Khan, This opinion piece provides a critical examination of the new rhetoric surrounding arboviruses as potential drivers of future pandemics, particularly ...
Meta-Analyses A Meta-Analysis of HIV Drug Resistance in Pakistan By Shafee Ur Rehman, HIV drug resistance (HIVDR) creates a threat to the extended success of antiretroviral therapy (ART) while making it harder to control the HIV epidemi...
Clinical Practice Article Quantitative Prediction of Visceral Pleural Invasion in Non-Small Cell Lung Cancer Based on Preoperative Contrast-Enhanced CT By Junjun Liang, Haotian Zhu, Yunjin Long, Longhuan Lu, Xin Yang, Huanwen Ding, Objective: To investigate the value of combining contrast-enhanced CT radiomic features, CT subjective features, and clinical information in the preop...
Meta-Analyses Intrathecal Dexmedetomidine Versus Fentanyl in Improving the Quality of Spinal Block in Lower Section Caesarean Section – A Meta-Analysis By ANWAR UL Ul HUDA, Mohammad Raheel Minhas, Opioids are the most used intrathecal adjuvants in lower section caesarean section (LSCS) but with associated side effects for both mothers and neonat...
Meta-Analyses Comparative Efficacy and Acceptability of Pharmacological Treatments for Ischemic Optic Neuropathy: A Multiple-Treatment Meta-Analysis By Qianxiong He, Many medicines have been shown to be ineffective in the treatment of ischemic optic neuropathy (ION). The effects of all/10 medicines for the treatmen...
Clinical Practice Article Implementation and Outcome Analysis of Enhanced Recovery After Surgery Protocol at a Tertiary Care Hospital By AZHAR REHMAN, Ausaf Ahmed Khan, Asma Abdus Salam, Objective: This study aimed to analyse the outcomes of surgeries performed at Aga Khan University Hospital using the ERAS protocol since its implement...
Clinical Practice Article Efficacy of Intradiscal Gentamicin in Preventing Disc Space Infection Following Lumbar Discectomy By Bilal Khan, Hubab Ali, Syed Mansoor Shah, Mukhtiar Ali Khan, Abdur Raheem, Noor Ullah, Background: To determine the efficacy of intra-discal gentamicin in preventing postoperative discitis in lumbar spine surgery. Study design: Observa...
Meta-Analyses Effects of Perioperative Transcutaneous Electrical Acupoint Stimulation On Sleep Quality After General Anesthesia: A Systematic Review and Meta-Analysis By Jing Ning, Chengfei An, Limeng Li, Jiacheng Zhang, Tao Tan, Huanan Li, This meta-analysis was designed to evaluate the efficacy and safety of perioperative transcutaneous electrical acupoint stimulation (TEAS) in improvin...
Meta-Analyses Efficacy and Safety of Pemafibrate in the Treatment of Dyslipidaemia: A Meta-Analysis By Weimin Huo, Hongbin Wang, Ran Wang, Yanting Wei, Jiajia Li, Fanfan Zhao, High plasma triglyceride (TG) is recognised as a significant risk factor for cardiovascular disease. Pemafibrate, a novel selective peroxisome prolife...
Short Communication Age-stratified Association between Health Literacy and Unmet Medical Needs among Korean Adults By Ki Dong Ko, In Cheol Hwang, Hong Yup Ahn, Identifying the factors associated with unmet medical need (UMN) is critical for designing interventional strategies. This nationwide cross-sectional ...
Clinical Practice Article Preserving the Recurrent Laryngeal Nerve Invaded by Thyroid Cancer By Hasan Calis, Kamil Ozturk, Nusret Yilmaz, Ramazan Sari, Cumhur Arici, Objective: To assess surgical management strategies for RLN (recurrent laryngeal nerve) invasion in patients with locally advanced thyroid cancer, w...
Short Communication Exploring Body Dysmorphic Disorder: A Cross-Sectional Survey By Saadiya Siddiqui, Faria A, Wajeiha Saeed, Ashba Nasir Cheema, Rashid Ali, Bushra Bashir, The aim of this descriptive, quantitative cross-sectional survey was to find the prevalence and explore different demographic characteristics of body ...
Short Article The Impact of Smoking On Lipid Profile in Males: A Cross-Sectional Study By Nasir Ashraf, Maha Abuzarifa, Yasir Ashraf, Fatima Qayyum Abbasi, Sehrish Imtiaz, Jahanzaib Khan, Objective: To assess the impact of cigarette smoking on lipid profile in 20-60-year-old male smokers and non-smokers. Study Design: Descriptive cross...
Clinical Practice Article Outcome of Focussed Parathyroidectomy in Hyperparathyroidism By Farhan Ahmed Majeed, Sohail Saqib Chatha, Mubashara Badar, Ahmad Raza, Bilal Umair, Nabeela Farhan, OBJECTIVES: To evaluate the surgical outcome of focused parathyroidectomy in the management of hyperparathyroidism STUDY DESIGN: Case Series PLACE A...
Commentary Mind-Motor Mat Training as an Early Adjunct to Anti-Hypertensive Therapy for Cognitive Preservation By Sana BASHIR, Arzoo Bashir, Mehreen Baig, Hypertension affects over 1.28 billion adults globally and remains a critical contributor to cardiovascular complications, mortality, and cognitive de...
Meta-Analyses Renal Sympathetic Denervation Plus Pulmonary Vein Isolation for Atrial Fibrillation with Hypertension: A Meta-Analysis of RCTs By Kun Wang, Na Yi, Yong Cai Liang, Jie Xion, Ting Wan, Background: This study aimed to assess the efficacy and safety of adding adjuvant renal sympathetic denervation (RSDN) to pulmonary vein isolation (PV...
Short Communication Factors Associated with The Survival of Head and Neck Cancer Patients: A Single Institution Experience from Karachi, Pakistan By UZMA SHAMSI, Namra Usman, Zeerak Jarrar, Romana Idress, Iqbal Azam, The objective of the study was to examine the clinicopathological features and survival rates of head and neck cancer (HNC) patients, from the Aga Kha...
Clinical Practice Article Clinical Characteristics, Treatment Response, and Prognosis between Saddle and Non-Saddle Pulmonary Embolism in Intermediate- to High-Risk Acute Pulmonary Embolism By Qihong Chen, Jinqi Huang, Objective: To investigate the clinical characteristics of patients with saddle pulmonary embolism (SPE) among those with intermediate- to high-risk ac...
Meta-Analyses Relationship Between Sleep Duration and Development of Hypertension in Women: A Meta-Analysis By Yan Bai, Deying Kong, Jie Hou, Li Bai, This study examined the association between sleep duration of females and the development of hypertension. Searches were conducted from Embase, PubMed...
Meta-Analyses Psychological Care in Heart Failure Rehabilitation: A Systematic Review and Meta-Analysis By Ruigui Zheng, Zhe Xue, Yijian YU, This meta-analysis aimed to evaluate the efficacy of psychological therapy versus conventional therapy within cardiac rehabilitation programs for indi...
Viewpoint A Novel Metric to Guide Cancer Priorities in Pakistan By Aashir Aslam, Syed Nabeel Zafar, Pakistan faces an escalating cancer burden, with approximately 185,748 new cases and 118,631 deaths annually. According to GLOBOCAN data, breast cance...
Short Communication The Predictive Role Of Triglyceride To High-Density Lipoprotein-Cholesterol Ratio And Triglyceride-Glucose Index In Glycemic Regulation Among Type 2 Diabetes Mellitus (T2DM) Patients With Chronic Kidney Disease (CKD) By Ayesha Iftikhar, Adnan Mustafa Zubairi, Fatima Kanani, Nadia Yaqub, This study explores the potential of the triglyceride to high-density lipoprotein-cholesterol (TG/HDL-C) ratio and the triglyceride glucose (TyG) inde...
Clinical Practice Article Predictive Value of D-Dimer Combined with Injury Severity Score for In-Hospital Mortality in Trauma By Peng Jiajian, Minhua Kuang, Zhangrong Liang, Qixin Yu, Objective: To evaluate the predictive performance of combining serum D-Dimer levels with Injury Severity Score (ISS) for forecasting in-hospital morta...
Short Communication Screening of Predictive Variables for Severe Hyperlipidemic Acute Pancreatitis By Gongchao Yu, Zhenxing Li, Kunfeng Yan, Xiaorong Dai, Qingyu Zhang, This retrospective observational study aimed to identify risk factors and screen predictive variables for severe hyperlipidemic acute pancreatitis (HL...
Clinical Practice Article Appropriateness of Antibiotic Dosing in Patients with Augmented Renal Clearance in Cardiovascular Surgery and Coronary Intensive Care Units By Ayşe Gül KoÇoĞlu Kinal, Yunus Emre AYHAN, Objective: To evaluate the appropriateness of antibiotic dosing in patients with augmented renal clearance (ARC) admitted to cardiovascular surgery (C...
Short Communication Patterns of Vascular Calcification and Stenosis in Peripheral Artery Disease: A CTA-Based Study of Disease Severity and Treatment Decisions By Dr Athar Badshah, Dr Muhammad Ismail, Brig Dr Nauman Imtiaz, Brig Dr Ahsin Manzoor Bhatti, Dr Anas Bin Saif, Dr Mustansar Hussain Haidri, Peripheral artery disease (PAD), a systemic form of atherosclerosis, causes limb ischemia, with disease severity critically determined by vascular cal...
Clinical Practice Article Is Staple Line Reinforcement Necessary in Sleeve Gastrectomy? A Retrospective Cohort Study Highlighting the Role of Surgical Technique By Surrender Dawani, Syeda Zarreen Raza, Rashid Ali, Madiha Masood Khan, Moosa Ashfaq, Tashaba Qaiser Faizi, Objective: To compare the frequency of postoperative complications, specifically staple line bleeding and leakage, in patients undergoing laparoscop...
Original Article Bioclear vs. Conventional Matrix in Anterior Black Triangles By Han Zheng, Anna Wang, Qiong Sun, Fuhua Zhang, Lei Zhang, Objective: To compare the 6-month periodontal outcomes and restoration quality between Bioclear and conventional resin restorations in anterior black ...
Original Article Artificial Intelligence-Based Digital Image Analysis Effectively Assesses KI67, P53, And PHH3 Expressions In Glioblastoma By Tuba Devrim, Gamze Erkılınç, Saniye Sevim Tuncer, Objective: To compare artificial intelligence (AI)-based analysis of Ki-67, PHH3, and p53 immunohistochemical (IHC) biomarkers in glioblastoma (GBM) w...
Meta-Analyses Prevalence of Cancer in Pakistan: A Meta-Analysis By Shafee Ur Rehman, Cancer continues to grow as a major public health issue in Pakistan because its occurrence and death rates keep increasing. The development of cancer ...
Clinical Practice Article Prediction of Post-Covid-19 Pulmonary Fibrosis: An Integrated Approach Combining CT Radiomics and Clinical Characteristics By Mujuan Wang, Pei Huang, Min Jiang, Bing Fan, Objective: To develop and validate a predictive model for post-COVID-19 pulmonary fibrosis (PCPF) using a combination of CT radiomics features and cli...
Clinical Practice Article A Comparative Evaluation of the Predictive Accuracy, Clinical Utility, And Application Efficiency of Four Nephrolithometric Nomograms for Percutaneous Nephrolithotomy Outcomes By Cagatay Ozsoy, Erhan Ateş, Goksel Tuzcu, Arif Kol, Objective: This study aimed to evaluate the predictive roles of four commonly used nephrolithometric nomograms - GSS, S.T.O.N.E., CROES and S-ReSC - i...
Clinical Practice Article Study on Endoscopic Spine Surgery in The Treatment of Degenerative Lumbar Spondylolisthesis With Spinal Stenosis in the Elderly By Chongchao Yan, Genwei Liu, Na Zhong, Zhongxu Bai, Jianpeng Zhang, Wenkui Zhao, Objective: To analyze the clinical outcomes of endoscopic lumbar interbody fusion for the treatment of degenerative lumbar spondylolisthesis with spin...
Short Article Dimensions of Anterior Cruciate Ligament (ACL) in Young Adults By Musharraf Jamil, Muhammad Arslan, Atif Ali, Fahad Iqbal, Akbar Abbas, Rizwan Akram, Objective: To measure the dimensions of the anterior cruciate ligament (ACL) in young adults and assess variations based on the demographic profile ...
Meta-Analyses The Clinical Efficacy of Local versus Intramuscular Injection of Methotrexate in the Treatment of Cesarean Scar Pregnancy: A Meta-Analysis By Peipei Zhou, Huihui Sun, Jingjie Song, Yunxia Ke, This meta-analysis were designed to compare of the clinical efficacy of local injection and systemic intramuscular injection of methotrexate in the tr...
New Technique Intraoperative Colonoscopy-Guided Localisation of Proximal Resection Margin in Sphincter-Preserving Surgery for Rectal Cancer After Neoadjuvant Chemoradiotherapy By Qiao Zhang, Shenghui Wang, Xianda Qiu, Xingrong Lu, Pan Chi, Zhifen Chen, The study was conducted to evaluate the feasibility and efficacy of intraoperative colonoscopy-guided proximal resection margin (PRM) localisation in ...
Short Communication Serum Retinol Binding Protein 4 Levels Among Hypertensive and Normotensive Individuals By Kiran Iftikhar, Muhammad Husnain, Noor Sehar, Muhammad Ahmad Malik, Saqib Sohail, The aim of this cross-sectional study was to compare serum Retinol Binding Protein 4 (RBP4) levels in hypertensive and normotensive non-obese individu...
Original Article Prognostic Impact of Wilms Tumour 1 Mutation in Acute Myeloid Leukaemia Patients By Maratib Ali, Manzar Bozdar, Sarah Fatimah, Rafia Mahmood, Tanveer Ahmed, Hatim Khalid, Objective: To detect WT-1 gene alterations among individuals diagnosed with Acute Myeloid Leukaemia (AML) and investigate its relation to the response...
Clinical Practice Article Mini-Mental State Examination Changes and Prediction of Cognitive Recovery after Stroke Following Cognitive-Motor Intervention By Hu Chen, Jingyuan Lin, Objective: To evaluate the impact of cognitive-motor intervention on cognitive function in stroke patients and to explore predictive factors for meani...
Short Communication The Effect of Skin Tag Presence on Medical Treatment Success in Chronic Anal Fissure Patients By Fikret Calikoglu, Zeliha Aydn Kasap, Tugba Koc Calikoglu, Kubra Isik, Ahmet Akbas, To determine whether skin tag is important in the success of treatment in patients with chronic anal fissure who received conservative treatment with ...
Clinical Practice Article Evaluating CKD-EPI Pakistan Against Standard Equations Using DTPA-Measured GFR By Muhammad Shahzil, Nayyar Saleem, Muhammad Rashid Asghar, Aimon Riaz, Noor Ul Ain, Ahmed Sheraz, Objective: To evaluate and compare the accuracy of creatinine-based equations (CKD-EPI Pakistan, CKD-EPI 2021, MDRD) against the gold-standard DTPA c...
Meta-Analyses Effects of Probiotics on Oral Microbiological Environment, Gingival Health, and Dental Plaque- A Meta-Analysis By MEHWASH KASHIF, Mahmooda Kazmi, Asfahan Shah, Syeda Nimra Qadri, This meta-analysis was conducted to assess the effects of probiotics on dental plaque and gingival health and oral microbiological environment. The Pu...
Commentary New Insights into Controlled Intracranial Decompression for Preventing Traumatic Acute Brain Bulge By Liang Xian, Shilong Fu, Ye Dan, Long Lin, Shousen Wang, Traumatic acute brain bulge is a life-threatening phenomenon. Traumatic acute brain bulge is usually classified into primary brain bulge and secondary...
Clinical Practice Article The Clinical Value of Neuropsychiatric Scales in The Preliminary Identification of Frontotemporal Dementia from Alzheimer's Disease By Lingfeng Zhang, Pengxing Lin, Yipan Zhang, Zhijian Lin, Objective: To provide reference for the clinical differentiation of behavioral variant of Frontotemporal dementia(bvFTD) and Alzheimer’s disease(AD)...
Short Article Development of a Machine Learning Model for Predicting Postoperative Pain after Root Canal Treatment By Zhijun Wei, Sheng Feng, Han Zheng, Qiong Sun, Fuhua Zhang, Lei Zhang, Objective: To develop and validate a machine learning (ML) model to predict postoperative pain following root canal treatment (RCT). Study Design: Ob...
Evidence-Based Report Analysis of Acquired Fusion Mutations in EGFR-TKIs Resistant Patients with Advanced Lung Cancer By Yuan Yang, Nana Zhang, Liang Shi, Zhaoxin Chen, Baohua Lu, Zhe Liu, The aim of this study was to determine the characteristics of non-small cell lung cancer(NSCLC) patients with fusion genes emerging after EGFR-TKIs re...
Short Article Identification and Clinical Consensus Evaluation of Drug-Drug Interactions in Cardiac Intensive Care Units By Ayşe Gül Kocolu Kinal, Yunus Emre AYHAN, Objective: To evaluate the frequency characteristics, and clinical relevance of potential drug-drug interactions (pDDIs) in Cardiovascular Surgery Int...
Commentary Ireland’s ADM (Capacity) Act 2015: Essential insights for International Medical Practitioners By Shankar Lal, Ehtesham Khan, Assisted decision-making (ADM) frameworks signify a revolutionary change in healthcare law and ethics, incorporating autonomy, dignity, and participat...
Original Article The Role of the Immature Granulocyte Value in Predicting Esophagojejunostomy Anastomosis Leakage After Total Gastrectomy By Abdullah Şenlikci, Umit Ozdemir, Ahmet Seki, Necip Tolga Baran, Habip Sari, Mustafa Taner Bostanci, Objective: To evaluate the role of the immature granulocyte value in the diagnosis of esophagojejunostomy anastomosis leakage. Study Design: Descript...
Original Article Association between SYNTAX Score and Neopterin Level in Patients with Chronic Coronary Artery Disease By Zeynep Yapan Emren, Sadik VOLKAN Emren, Oktay Senoz, Levent Elmas, Objective: To explore the relationship between the Synergy between PCI with TAXUS and Cardiac Surgery (SYNTAX) score and neopterin levels in coronary ...
Original Article Comparison of Letrozole with Elagolix for Medical Management of Endometriosis Associated Pain: A Quasi-Experimental Study By Shamila Ijaz Munir, Alia Nasir Ud Din, Sofia Iqbal, Hina Irshad, Ujala Hussain, Objectives: To compare the efficacy of Letrozole and the Elagolix in the medical management of endometriosis associated pain Study design: Quasi-expe...
Original Article Frequency of Anti-Ganglioside Antibodies and Their Clinical Correlates with Guillain-Barré Syndrome: A Single-Centre Study in Pakistan By Mustajab Alam, Hamid Nawaz Tipu, Aamir Hussain, Muhammad Hussain, Wasim Wali Muhammad, Objective: To determine the frequency of anti-ganglioside autoantibodies and their clinical associations in patients clinically suspected of Guillain-...
Original Article Validation of The Ohip-14 And Analysis of Gender and Treatment Differences in Oral Health-Related Quality of Life Among Pakistani Dental Patients By Mahnoor Fatima, Muhammad Saqib, Muhammad Waasay Tanweer, Mahad Bin Nadeem, Fatima Ehsan, Javed Ashraf, Objective: This study aims to compare the impact of root canal treatment (RCT) versus tooth extraction using Urdu version of OHRQoL in a sample of Pak...

Epub Ahead of Print

Complete Remission in BCLC stage C Hepatocellular Carcinoma Treated with HAIC Combined with PD1 Inhibitors and Anti-angiogenic Therapy

The Educational Application of Teacher-made Mind Maps on Students

Efficacy of Sofosbuvir and Daclatasvir Combination Treatment in Chronic Hepatitis C in Patients Among Haemodialysis Patients

Electrical Impedance Tomography-Guided Positive End-Expiratory Pressure Titration in Acute Respiratory Distress Syndrome: A Meta-Analysis

Medical students’ deaths by suicide in Pakistan: An alarming trend and a Call for Action

Imaging features and clinicopathology of adenoid cystic carcinoma of the head and neck

Nicotine dependence as a prognostic factor for glycemic control in non-diabetic smokers: A nationwide Korean survey

Beyond the waves: Assessment of the clinical appropriateness of electroencephalography referrals in neurological practice

Clinical Utility of Ultrasound-Guided Midline Catheters in Cardiovascular Intensive Care Unit

Simulation based training for Limberg Flap Technique for Pilonidal Sinus through task trainer: Strategy to enhance surgical skills.

Ventilator Associated Pneumonia as Biggest Challenge: Incidence, Risk Factors, Prevention and Mortality Rate

Empowering health care professionals with the innovative ‘five tips’ approach.

Non-Communicable Diseases and Their Implications in Pregnant Women- Results from a Cross-Sectional Study in Pakistan

Comparison of Classical Blood Cardioplegia and Modified Del Nido Cardioplegia on Postoperative Serum Lactate, and Extubation Times.

Role of n-acetylcysteine in the prophylaxis against contrast induced nephropathy: A meta-analysis

EVALUATION OF TEMPOROMANDIBULAR JOINT BONE DEGENERATIONS USING CONE BEAM COMPUTED TOMOGRAPHY in KENNEDY CLASS I and CLASS II PARTIALLY EDENTULOUS PATIENTS

Bleomycin-lipiodol emulsion combined with polyvinyl alcohol particles in the treatment of focal nodular hyperplasia of the liver: initial experience and literature review

A COMPARATIVE ANALYSIS OF MINIMALLY INVASIVE SURGICAL METHODS IN ESOPHAGECTOMY: A REVIEW STUDY.

Is the classification of Ventilator-Associated Pneumonia as early and late-onset useful?: A comparison of microbial profile, antibiotic susceptibility and mortality

Uncinate Processes Inner Margins Guide Quick and Mid-line Placement of Multilevel Plate on Cervical Vertebra with Severe Osteophyte and Technique Notes

Low-Dose Tamoxifen for Breast Noninvasive Disease: A Meta-Analysis

Palliative care in the Emergency Department: A step in the right direction

Dedicated Brain Injury Rehabilitation Units need in Pakistan

THE MODIFIED FRAILTY INDEX-5 AS A PREDICTOR OF POSTOPERATIVE COMPLICATIONS IN PATIENTS UNDERGOING RADICAL CYSTECTOMY

Influencing factors and predictive model construction for lower extremity deep vein thrombosis after total knee arthroplasty

Toward Connected Care: Why Pakistan Needs Integrated Electronic Health Records

A DEEP LEARNING APPROACH TO DETECTION OF ORAL LEUKOPLAKIA LESIONS FROM INTRA ORAL PATIENT IMAGES USING FOUR DIFFERENT ALGORITHMS: A PRELIMINARY RETROSPECTIVE STUDY

A New Duodenum Traction Technique in Laparoscopic Treatment of Duodenal Obstruction in Neonates

Antibiotic and Microbiological Profiles in Hidradenitis Suppurativai

Symptoms, Triggers and Prodromes of Hereditary Angioedema in Pakistani Population

Development of the Kyphosis Cardiopulmonary Resuscitation (K-CPR) Technique in Patients with Spinal Mobility Restriction Due to Ankylosing Spondylitis

Relationship between the Atherogenic Index of Plasma and Glycated Haemoglobin A1c, Serum Uric Acid and Homocysteine in Type II Diabetes and Acute Stroke

Cutaneous Histoplasmosis in HIV Patients: Brief Review

Clinical Presentation and Outcome of Patients Undergoing Surgery for Thyroid Cancer

GnRH Agonists and Antagonists in IVF/ICSI Cycles of PCOS Women: A Network Meta-Analysis

Gamifying Neurology: Lessons from The NExCARD Experience in Emergency Medicine Training

Diagnostic Odyssey of CT Cystography in Unravelling Traumatic Bladder Injuries

Significance of Herbs in Dental World

Significance of Herbs in Dental World

Significance of Herbs in Dental World

Radiotherapy-Chemotherapy Combinations in Locally Advanced Head and Neck Squamous Cell Carcinoma

Comparative Efficacy of Conventional Milligan-Morgan and Ferguson Hemorrhoidectomy versus Diode Laser Hemorrhoidoplasty for Symptomatic Hemorrhoids: A Meta-Analysis based on RCT

The Urgent Need for AI- guidelines and framework for Medical Education and Research in Pakistan

Efficacy of Topical 5–Fluorouracil Combined with Microneedling in the Treatment of Stable Vitiligo

Assessment of Acetabular Fractures Fixation with Modified Harris Hip Score Regarding Clinical and Functional Outcomes

HCV Seropositivity Versus Care Non-compliance in Shenzhen Blood Donors

Effects of Ulinastatin and Tranexamic Acid in Cardiac Surgery: A Systematic Review and Meta-Analysis

Factors Predicting Cognitive Dysfunction End Stage Renal Disease

A Comprehensive Assessment of Acute Stroke Care: Delays, Treatment Patterns, and Barriers to Timely Intervention

A Systematic Reviews and Meta Analyses of Liquid Biopsy Based Multimodal Approach for the Diagnosis of Pulmonary Nodules

The Paradox of a Pandemic Stalled by an Empty Sting

A Meta-Analysis of HIV Drug Resistance in Pakistan

Quantitative Prediction of Visceral Pleural Invasion in Non-Small Cell Lung Cancer Based on Preoperative Contrast-Enhanced CT

Intrathecal Dexmedetomidine Versus Fentanyl in Improving the Quality of Spinal Block in Lower Section Caesarean Section – A Meta-Analysis

Comparative Efficacy and Acceptability of Pharmacological Treatments for Ischemic Optic Neuropathy: A Multiple-Treatment Meta-Analysis

Implementation and Outcome Analysis of Enhanced Recovery After Surgery Protocol at a Tertiary Care Hospital

Efficacy of Intradiscal Gentamicin in Preventing Disc Space Infection Following Lumbar Discectomy

Effects of Perioperative Transcutaneous Electrical Acupoint Stimulation On Sleep Quality After General Anesthesia: A Systematic Review and Meta-Analysis

Efficacy and Safety of Pemafibrate in the Treatment of Dyslipidaemia: A Meta-Analysis

Age-stratified Association between Health Literacy and Unmet Medical Needs among Korean Adults

Preserving the Recurrent Laryngeal Nerve Invaded by Thyroid Cancer

Exploring Body Dysmorphic Disorder: A Cross-Sectional Survey

The Impact of Smoking On Lipid Profile in Males: A Cross-Sectional Study

Outcome of Focussed Parathyroidectomy in Hyperparathyroidism

Mind-Motor Mat Training as an Early Adjunct to Anti-Hypertensive Therapy for Cognitive Preservation

Renal Sympathetic Denervation Plus Pulmonary Vein Isolation for Atrial Fibrillation with Hypertension: A Meta-Analysis of RCTs

Factors Associated with The Survival of Head and Neck Cancer Patients: A Single Institution Experience from Karachi, Pakistan

Clinical Characteristics, Treatment Response, and Prognosis between Saddle and Non-Saddle Pulmonary Embolism in Intermediate- to High-Risk Acute Pulmonary Embolism

Relationship Between Sleep Duration and Development of Hypertension in Women: A Meta-Analysis

Psychological Care in Heart Failure Rehabilitation: A Systematic Review and Meta-Analysis

A Novel Metric to Guide Cancer Priorities in Pakistan

The Predictive Role Of Triglyceride To High-Density Lipoprotein-Cholesterol Ratio And Triglyceride-Glucose Index In Glycemic Regulation Among Type 2 Diabetes Mellitus (T2DM) Patients With Chronic Kidney Disease (CKD)

Predictive Value of D-Dimer Combined with Injury Severity Score for In-Hospital Mortality in Trauma

Screening of Predictive Variables for Severe Hyperlipidemic Acute Pancreatitis

Appropriateness of Antibiotic Dosing in Patients with Augmented Renal Clearance in Cardiovascular Surgery and Coronary Intensive Care Units

Patterns of Vascular Calcification and Stenosis in Peripheral Artery Disease: A CTA-Based Study of Disease Severity and Treatment Decisions

Is Staple Line Reinforcement Necessary in Sleeve Gastrectomy? A Retrospective Cohort Study Highlighting the Role of Surgical Technique

Bioclear vs. Conventional Matrix in Anterior Black Triangles

Artificial Intelligence-Based Digital Image Analysis Effectively Assesses KI67, P53, And PHH3 Expressions In Glioblastoma