Impact Factor 0.711 5 Year Impact Factor 0.735
Volume 32, 12 Issues, 2022

Epub Ahead of Print

Vaginal Leiomyoma Presenting As Pelvic Organ Prolapse In Pregnancy

By Saida Abrar, Dr Raheela Mohsin,

Vaginal leiomyomas are extremely rare in pregnancy. These can present in a variety of ways. They can cause mechanical obstruction leading to maternal ...


Colonic Metastasis from Primary Tonsillar Squamous Cell Carcinoma: A Rare Cause of Large Bowel Obstruction

By Tayfun Kaya, Semra Demirli Atıcı, Dudu Solakolu Kahraman, Huseyin Salih Semiz, Duygu Kahraman,

Tonsillar squamous cell carcinoma is a subtype of head and neck cancers which rarely metastasizes to the colorectal system. Colonic metastasis seconda...


Gossypiboma: The Forgotten Foreign Bodies and Surgeon’s Nightmare

By Usman Akbar, Adil Khan, Mustafa Rahim, Faiza Ahmed,

Gossypiboma, first described by Wilson in 1881, is a term that originated from the Latin word Gossypium (meaning “cotton”) and suffix -oma (mea...


T-cell acute lymphoblastic leukemia in an infant: a case report and review of literature

By Neelum Mansoor, Naeem Jabbar,

A high index of suspicion of acute leukemia in infants presenting with atypical clinical and laboratory features is of paramount importance to avoid t...


A Rare Co-Existence of Multiple Cerebral Cavernous Malformations and Pleomorphic Adenoma of The Parotid Gland in Myotonic Dystrophy

By Sadaf Iftikhar, Muhammad Zeeshan Sarwar,

Myotonic dystrophy is an autosomal dominant inherited disorder primarily affecting the muscle function. Myotonia, progressive muscle weakness and wast...


Carpometacarpal Joint Dislocations as a Rare Cause of Hand Pain: A Case Report

By Ali Çelik,

Carpometacarpal joint dislocations represent not more than 1% of all hand injuries due to stable joint structures and high energy trauma mechanism. Un...


Control of Oesophageal Tumour-Related Bleeding With A Temporary, Fully Covered Self-Expandable Metallic Stent (Sems) Insertion: A Case Report

By Muhammad Zeeshan Siddique, Muhammad Saqib, Jhanzeb Iftikhar, Muhammad Aasim Yusuf,

The role of metallic stents in the management of refractory variceal bleeding is now well established; however, they have been rarely used in treatmen...


It Does Exist! Traumatic Hemorrhage in Septum Pellucidum

By Murat Seyit, Arif Osun, Atakan Yilmaz, Mert Ozen, Duygu Aras Seyit,

Although bleeding into the septum pellucidum often occurs in the presence of a tumour, trauma-induced septal pellucidum hemorrhage has not been report...


Renal Cell Carcinoma Of Pelvic Kidney With Atypical Nodal Metastasis: A Diagnostic Challenge

By Roshane Shahid Rana, Muhammad Hammad Ather,

Ectopic pelvic kidney is a known congenital anomaly; however, presence of renal cell carcinoma (RCC) in an ectopic kidney is rare with evidence availa...


Atypical Presentation of A Primary Thymic Adenocarcinoma: A Case Report

By Hasan Ersöz, Ebru Cakir, Utku Oflazoglu, Berna Dernek,

Primary thymic adenocarcinomas are extremely rare and aggressive tumors. In this report, clinical and histopathological findings of this rare entity a...


Epithelioid inflammatory myofibroblastic sarcoma with leukemoid reaction

By Yuan Yuan Wan, Cheng Li Miao, Shi Bo Liu, Tong Zhang, Cheng Hua Luo,

Epithelioid inflammatory myofibroblastic sarcoma (EIMS) is a rare and aggressive inflammatory myofibroblastic tumor (IMT) variant. Our report identifi...


Mucormycosis of Maxilla: An Enigma To The Clinician

By Suman Sen,

Mucormycosis is an acute opportunistic infection caused by a saprophytic fungus found in soil, and decaying fruits and vegetables. It is a rapidly pro...


Non-Surgical Management of Lingual Hemangioma by Combined Sclerotherapy and Cryotherapy: A Case Report

By SHAUL HAMEED KOLARKODI, Muhammad Qasim Javed, Mohammed Rafeeq P K, Dhafer Alasmari, Mohammed Faiz C P,

Hemangioma is frequently seen benign tumor of vascular origin, typed into capillary and cavernous hemangiomas based on the nature of vessels in the le...


Saved by the clot in superior vena cava injury: a case report

By Pratikshya Thapaliya, Tanveer Ahmad, Nazish Sikander, Misauq Mazcuri, Ambreen Abid,

Penetrating neck injuries (PNIs) can cause injuries to great vessels. Superior vena cava (SVC) injury from stab to neck is rare and when it occurs,  ...


Granulomatous Inflammation of Greater Omentum Caused by a Migrating Fish Bone

By Qi Chao Wang, Yan Wan Wu, Nan Ya Wei, Tao Xu Li, Tao Fan, Jie Ying Song,

Fish bone is the most common ingested gastrointestinal foreign matter and less than 1% perforate. However, a fish bone penetrating the gastrointestina...


A Rare Case of Female Bladder Outlet Obstruction: Severe Introital Stenosis

By Muhammed Fatih Simsekoglu, Oktay Ozman, Mehmet Hamza Gultekin, Bulent Cetinel,

Herein, we report a rare case of severe introital stenosis in a 22-year female who presented with obstructive voiding symptoms and inability to have s...


Unusual Appearance of Nasal Collagenous Fibroma (Desmoplastic Fibroblastoma) on Imaging

By Xiaolong Liu, Xiang Guo, Linsheng Wang, Yueqin Chen, Hao Yu, Zhanguo Sun,

Collagenous fibroma (CF) is a benign soft tissue tumour with good prognosis. Preoperative imaging diagnosis is essential to avoid unnecessary extended...


Cutaneous T Cell Lymphoma Predisposing to Recurrent Infective Endocarditis by Methicillin-Resistant Staphylococcus In A Patient with Intracardiac Defibrillator

By Muhammad Azam Shah, Muhammad Adil Soofi, Faisal Alsmadi, Muhammad Amin Ur Rehman, Faisal Abdullah Alghamdi,

Cutaneous T cell lymphoma (CTCL) is a rare group of extra-nodal non-Hodgkin's lymphomas resulting in infiltration of the skin by malignant cells. ...


Disseminated nocardiosis with ocular involvement in a patient with ANCA-associated vasculitis

By Ayşe Bahar Keleşoğlu Dinçer, Serdar Sezer, Mucteba Enes Yayla, Gulay Kinikli,

A 62-year male patient, diagnosed with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), developed proptosis and decrease in vis...


Spontaneous cervical epidural abscess caused by serratia marcescens: A case report

By Idris Sertbaş, Derya Bayirli Turan, Mete Karatay,

Serratia marcescens infections are very rare and are usually occur in the form of nosocomial and opportunistic infections. The subjects usually have s...


Brucella Prosthetic Infection in a Patient with Total Knee Prosthesis: A Case Report

By Sabit Numan Kuyubasi, Sermet Inal, Alaadin Oktar Uzumcugil, Sevil Alkan Ceviker, Bunyamin Ari,

Brucella infection is often an occupational disease of veterinarians, agricultural workers and slaughterhouse workers. The infection is generally spre...


Role of Recombinant activated factor VIIa (rFVIIa) in bleeding mycotic aneurysm of abdominal aorta

By Irfan Ahsan, Karimullah Makki, Sidra Rauf, Shaheen Sultan,

Mycotic aortic aneurysm is an infective disease of aorta with high mortality rate despite surgical repair. Recombinant activated factor VIIa (rFVIIa)...


Spontaneous Forniceal Rupture Identified By Point of Care Ultrasound: Case Report

By Ali Çelik, Mehmet Altuntaş,

Spontaneous forniceal rupture is one of the rarest diagnosis of abrupt onset abdominal pain. Moreover, urolithiasis is the most prevalent cause and co...


SRD5A3-CDG: a patient with a novel variant and brain neoplasm

By Cigdem Seher Kasapkara, Asburce Olgac, Betul Emine Derinkuyu, Ulkuhan Oztoprak, Jaak Jaeken,

Congenital disorders of glycosylation (CDGs) are a large group of genetic diseases with impaired glycosylation of glycoproteins and glycolipids, and g...


Unusual Sites of Leiomyosarcoma: A Medley of 3 Interesting Cases

By Bushra Siddiqui, Shahbaz Habib Faridi, Asfa Shams, Jowairiah Hassan,

Leiomyosarcomas are malignant tumours arising from smooth muscle cells. They are rapidly growing tumors with aggressive behaviour and poor prognosis. ...


Cecal Dıvertıculıtıs: A Dıagnosıs To Keep In Mınd When Evaluatıng Acute Appendıcıtıs

By Hakan Bolukbasi,

Caecal diverticulitis is a rare cause of right lower quadrant abdominal pain. As its symptoms mimic those of acute appendicitis, the final diagnosis i...


Insidious onset of Localised Small Intestinal Perforation by ingested Plastic Fork

By Serhan Yilmaz, Hüsnü Aydın, Hakan Bolukbasi,

Ingestion of a foreign body is generally observed in psychiatric patients and children. Adult healthy individuals may also swallow a foreign body unin...


Two Cases of Interrupted Inferior Vena Cava with Azygos/Hemiazygos Continuation

By Saerah Iffat Zafar, Aliya Halim, Waqas Khalid, Mobeen Shafique, Hina Nasir,

Interrupted inferior vena cava (IVC) is a rare disease, occurring either in isolation or in association with asplenia or polysplenia syndromes. Infrah...


Neurobrucellosis Manifesting as an Altitudinal Visual Field Defect: A Rare Case

By Gursan Gunes Uygun, Sevcan Yildiz Balci, Hulya Tireli,

Brucellosis is a zoonotic disease with a wide range of ophthalmic manifestations, including optic neuritis. It is most commonly caused by the consumpt...


SUPERIOR MESENTERIC ARTERY SYNDROME

By ASIF ALI AMIR ALI, Kanwal Hameed, Ali Nawaz, Imran Khan, Sughra Perveen,

We report a rare case of upper gastrointestinal obstruction diagnosed in a 15 years old boy presenting with a 6 months long history of recurrent abdom...


Digital Necrosis Due to Septic Embolism: An Unseen Complication of Gangrenous Cholecystitis

By Nazmi ÖZER, Abdullah Sahin,

  Gangrenous cholecystitis is one of the most severe complications of cholelithiasis. It causes serious morbidity and mortality. The main pathology i...


Association Between Serum Carcino-Embryonic Antigen Levels And Micropapillary Bladder Cancer Metastasis in an Elderly Male

By Caner Ediz, Neslihan Kaya Terzi, Serkan Akan, Omer Yilmaz,

We herein present a case of a micropapillary variant of bladder cancer metastasizing to lymph nodes in an 87-year male with elevated serum carcinoembr...


Fibrolipoma of Tongue: A rare entity

By Salima Mansoor Ali, Nausheen Yaqoob, Anila Haneef, Sunder Sham, Asif Ali Arain,

Lipomas are benign mesenchymal tumors that comprise almost one-half of all soft tissue tumors. Lipomas can occur at any site where fat cells are prese...


First documented case of pulmonary alveolar proteinosis with atopy presenting secondary to CSFR2B mutation

By Ayse Senay Sasihuseyinoglu, Dilek Dogruel, Arbil Avci, Gursu Kiyan,

Pulmonary alveolar proteinosis (PAP) is a rare lung disorder in which surfactant-derived lipoproteins accumulate excessively within pulmonary alveoli,...


Lafora body epilepsy: A challenging diagnosis

By Ali ZOHAIR Nomani, Haris Majid Rajput, Hanna Nomani,

Lafora body disease (LBD) is a progressive myoclonic genetic epilepsy syndrome characterized by the presence of Lafora inclusion bodies within neurons...


Takayasu arteritis with isolated headache and neck pain: A Case Report

By Doctor Nazia Arain, Dr Shamsuddin Shaikh, Jawad Ali,

Takayasu Arteritis (TA),  a  chronic inflammatory condition of the aorta and its major branches,  causes narrowing and ultimate occlusion of major ...


Primary Hepatic Sarcomatoid Carcinoma presenting with Dysphagia: a rare presentation

By Khadim Hussain Samejo, Rajesh Mandhwani, Zain Majid, Muhammed Mubarak, Nasir Hassan Luck,

A 50-year male presented with vomiting and dysphagia for 2 weeks. Laboratory workup showed a positive serology for hepatitis C and normal serum α-fet...


Giant sigmoidal lipoma protruding through anal canal and causing sigmoidorectal intussusception

By Ali Surmelioglu, Serhat Ozer,

Intussusception is a rare condition in adulthood and there exists an underlying pathological lesion in most cases. Colorectal lipoma is the second mos...


Sturge-Weber Syndrome with Bilateral Fronto-parieto-temporal Lobe Atrophy and Bilateral Leptomeningeal Angiomatosis: A Rare Case

By Dr Ashok Kumar, Imtiaz Ali Panhwar, Bushra Rehan, Kanchan Shadani,

Sturge-Weber Syndrome (SWS) is a phacomatosis characterized by a Port-Wine stains, leptomeningeal angiomatosis, and glaucoma. Leptomeningeal angiomato...


Coexistence of Colon Perforation And Congenital Lipodystrophy in A Young Adult: A Rare Entity

By Nihan Acar, Turan Acar, Beste Suataman, Neşe Ekinci, Fatma Tatar,

Lipodystrophy (LD) is an acquired or congenital rare condition consisting of hyperlipidaemia, glucose intolerance/ insulin resistance, and almost comp...


Central Pancreatectomy for Solid Pseudopapillary Tumour of Pancreas in A 13-Year Girl

By Abdul Wahab Dogar, Shamsuddin Zehri, Hasnain Abbas, Irfan Haider,

Solid Pseudopapillary Tumour (SPT) is a very rare tumour of pancreas.  A 13-year girl presented to us with the complaint of upper abdominal pain and...


Salvage for postpartum massive hemorrhage in a Jehovah’s Witness with intravenous iron therapy and cell saver system

By TUGBA SARAC SIVRIKOZ, Cigdem Kunt Isguder, Muhterem MELIS Canturk, Mukadder Orhan Sungur, Sevgi Kalayoglu Besisik,

Intraoperative cell salvage (ICS) system performs autologous transfusion by filtering and reinfusing the shed blood into corporeal circulation during ...


Salvage intrapartum splenectomy for the treatment of transfusion-refractory anemia in a ß-thalassemia intermedia patient

By Tugba Sarac Sivrikoz, Murat Ozbalak, Aykut Ozmen, Mustafa Tukenmez, Sevgi Kalayoglu Besisik,

Thalassemia intermedia (TI) patients may need transfusion during physiological stress conditions, such as pregnancy. We present a case of a female TI ...


A Rare Case in Urology: Inflammatory Myofibroblastic Tumor

By Murat Akgül, Mehmet Fatih Sahin, Meltem Oznur, Aysegul Arslan, Cenk Yazici,

Inflammatory myofibroblastic tumor (IMT) is a soft tissue malignancy with a mixture of myofibroblastic spindle cells with hyalinized stroma and inflam...


Invasive and Non-invasive Ductal Carcinoma within Malignant Phyllodes Tumour with Axillary Lymph Node Metastases

By Osman ERDOGAN, Alper Parlakgumus, Zeynel Abidin Tas, Kemal Yener, Umit Turan,

Phyllodes tumours are uncommon breast neoplasms constituting 1-2% of breast malignancies. Metastasis is usually haematogenous, and axillary lymph node...


A Giant Esophageal Epiphrenic diverticulum causing dysphagia, fungal infection and aspiration pneumonia in an elderly patient

By Sabhita Shabir Shaikh, Raheela Khalid,

Esophageal epiphrenic diverticulum is a rare condition. We present a case of a 70-year male with no known co-morbidities who presented with dysphagia,...


The Fate of Coracoid Graft after Latarjet Procedure:Arthroscopic and Open Findings of Graft Union and Glenoid Remodelling

By Mohd Nizlan Mohd Nasir, Raymond Yeak Dieu Kiat, Ahmad Hisham Rashid,

Successful Latarjet procedures depend on many factors, including graft union and subsequent restoration of the glenoid surface. Coracoid graft union h...


Diabetic myonecrosis; A vascular complication

By Daniyal Nadeem, Nanik Ram,

Diabetic myonecrosis is an unpublicized problem that can occur in patients having either type 1 or type 2 diabetes mellitus. It usually effects patien...


A Rare Case of Post-pubertal Pure Yolk-sac Tumor Incidentally Diagnosed After Surgical Intervention for Fournier’s Gangrene

By Hakan Bahadir Haberal, Fariba Amini, Deniz Ates Ozdemir, Ahmet Gudeloglu, Ahmet Asci,

Testicular tumor is the most common solid malignancy in males between the ages of 15 and 35 years. Testicular tumors most commonly present with a pain...


A Case of Euglycemic Diabetic Ketoacidosis Due To Empagliflozin Use in A Patient With Type 1 Diabetes Mellitus

By Satilmis Bilgin, Tuba Taslamacioglu Duman, Ozge Kurtkulagi, Feyza Yilmaz, Gulali Aktas,

Euglycemic diabetic ketoacidosis is characterized by serum blood glucose <250 mg/dl, arterial blood pH <7.35 and the presence of ketones in urine or b...


Cystic Neutrophilic Granulomatous Mastitis: Case Series and Literature Review

By Qurat Ul Ain Zahid, Nausheen Yaqoob, Nausheen Feroz, Sheema Habib Hasan,

Granulomatous lobular mastitis (GLM) is an infrequent inflammatory breast disease, which can simulate malignancy on the basis of clinical and imaging ...


Posterior Fascicular Ventricular Tachycardia: A Rare Cause of Tachycardia

By Erdem Kurt, Rohat Ak, Suphi Bahadrl,

A 13-year male patient with a history of tachycardia attacks was diagnosed to have left posterior fascicular ventricular tachycardia (VT) according to...


Huge primary intermediate-grade myofibroblastic sarcoma in the retroperitoneum: a case report

By Huang Hong Jun, Wu Zhi Ming, Meng Xing Cheng, Chen Yong Liang, Han Qi,

Myofibroblastic sarcoma is exceedingly rare, with low-grade features in most cases, and rarely involves the retroperitoneum. The 2020 World Health Org...


Primary Hepatic Angiosarcoma: A Rare And Very Aggressive Liver Tumor

By Selahattin Durmaz, Muzaffer Basak, Banu Yilmaz Ozguven, Kamile Gulcin Eken, Sukru Mehmet Erturk,

Primary hepatic angiosarcoma (PHA) is a sporadic and aggressive tumour of the liver that originates from mesenchymal cells and represents less than 2%...


Percutaneous biopsy of metastatic bone lesions invisible on conventional computed tomography: case series

By Cennet Sahin, Fevziye Kabukcuoglu,

Early detection and histopathological diagnosis of a bone lesion that is suspicious for metastasis is crucial to plan treatment in cancer patients. We...


Finger flexor weakness in Myasthenia Gravis

By Mohammed H Alanazy, Hisham Alkhalidi,

Myasthenia gravis (MG) affects ocular, bulbar, and proximal limb muscles. The involvement of distal limb muscles of wrist, fingers and feet are uncomm...


PENILE FRACTURE AT THE CRUS OF THE PENIS -A Rare CASE REPORT .

By Saddaf Hina, Nadeem Iqbal, Muhammad Khilan Khilan, Aizaz Khan, C J Shukla,

Penile fracture is an uncommon acute surgical emergency, typically  occuring after sexual intercourse, self-manipulation and at times, may be acciden...


Solıd Renal Mass in A Transplanted Allograft Kıdney: Mucınous Tubular and Spındle Cell Renal Cell Carcınoma

By Erdinc Dincer, Osman Murat Ipek, Sukran Sarikaya Kayipmaz, Oktay Akca,

Renal transplantation is the main treatment of end-stage kidney disease. Transplantation reduces mortality rate and increase life quality in this popu...


Early enteral nutrition tolerance in a duodenal fistula patient undergoing open abdomen with vacuum-assisted temporary abdominal closure: A case report

By Junfang Zhang, Zhilong Yang, Heng Zhang,

This case sought to manage a duodenal fistula patient who underwent open abdomen with vacuum-assisted temporary abdominal closure (VAC) by evaluating ...


A case of spontaneous ovarian artery haemorrhage in a post-menopausal woman with congenital solitary kidney

By Chen Lu Min, Feng Jiang, Hong Jie Hu,

Ovarian arterial haemorrhage (OAH), a rare cause of spontaneous retroperitoneal hematoma (SRH), usually occurs in women during pregnancy or in those w...


Papillary Urothelial Carcinoma Arising From Ureterocele. Is It Really a Rare Occurrence?

By Ayhan Karakose, Ekrem Akdeniz,

Various hydronephrotic, dysplastic or clinical pathologies can accompany ureterocele, a cystic dilatation of the intravesical part of the submucosal u...


Malignant Glomus Tumor of the Ureter: A Case Report

By Mehmet Demir, Adem Tuncekin, Ismail Yagmur, Asli Aydogdu,

Although glomus tumour is usually seen in the subungual region of the extremities, it may rarely occur in visceral organs. Approximately 1% of all glo...


A Novel Varıant in Paıred Box 3 Gene Related wıth Waardenburg Syndrome Type I in An Afghan Famıly

By Mustafa Doğan, Recep Eroz,

Waardenburg Syndrome (WS) is a congenital auditory-pigmentary syndrome. We herein present a case of a 1.5-year girl presenting with bilateral hearing...


Symptomatic Spinal Seeding Metastasis of a Low-Grade Oligodendroglioma

By EMRAH KESKİN, Hasan ALI Aydin, Burak Bahadir, Kenan Simsek, Murat Kalayci,

Extracranial metastases from primary brain tumors are mostly caused by high-grade tumors. Metastases from low-grade intracranial tumors are much rare ...


A Case of Thyroid Follicular Carcinoma Presenting with Skin Metastasis

By Mustafa Eroglu, Uğur Ergün,

Skin metastases due to thyroid carcinomas are extremely rare and represent advanced disease and poor prognosis. Diagnosing a skin nodule, which may ap...


Glucagonoma Syndrome: A Rare Paraneoplastic Disorder Due To Neuroendocrine Tumor of the Pancreas

By Wania Imtiaz, Muhammad Zeeshan Siddique, Muhammad Saqib, Jhanzeb Iftikhar, Shafqat Mehmood, Muhammed Aasim Yusuf,

Glucagonoma syndrome is an extremely rare paraneoplastic disorder. The key presenting feature is a rash (necrolytic migratory erythema) which can easi...


Broad Complex Tachycardia, Addison's Disease, And Ascending Flacid Paralysis: An Interesting Case on Cardiology Floor

By NAUMAN ALI,

Broad complex tachycardia is a common presentation in cardiology emergency room but is not always due to ventricular tachycardia, especially in a youn...


Assessment of Pathological Complete Response In Patients With Breast Cancer Receiving Neoadjuvant Systemic Therapy

By Nida Farrukh, Razia Bano, Syeda Rifaat Qamar Naqvi, Humera Latif,

Objective: To quantify rate of pathological complete response (pCR) in a tertiary care hospital of Pakistan, and to explore association of pathologica...


Ectopıc Cushıng’s Syndrome Due To Thymıc Neuroendocrıne Tumor Treated wıth Surgery and Radıotherapy

By Yasemin Emur Gunay, Irfan Nuhoglu, Savas Volkan Kisioglu, Safak Ersoz, Damla Tufekci,

The most common cause of ectopic Cushing’s syndrome is small cell lung cancer; less common causes include pancreatic and thymic neuroendocrine tumor...


Solıtary Plasmacytoma in A Patıent Presentıng Wıth Taste Dısturbance

By Uğur Ergün, Ayse Uysal, Hasmet Yazici,

Solitary plasmacytoma is a disease included in plasma cell dyscrasias, presenting outside of the bone marrow, and with the potential to turn into mult...


Treatment of a Cyst of the Canal of Nuck with an Inguinal Hernia by Laparoscopic Surgery

By Veysi Hakan Yardimci,

A cyst of the canal of Nuck is a rare cystic structure along the inguinal canal extending to the labium majus, which forms due to non-obliterated proc...


Borderline-resectable undifferentiated carcinoma with osteoclast-like giant cells of the pancreas: upfront surgery or neoadjuvant chemotherapy?

By Alper Sozutek, Elife Aktas,

Undifferentiated carcinoma with osteoclast-like giant cells (UDC-OGC) of the pancreas is an extremely rare entity, thus an obvious discrepancy regardi...


Adult Vanishing White Matter Disease with a Novel EIF2B4 Mutation: A Case Report

By Ting Su, Haijun Yuan, Wei Gao, Huaxin Li, Mei Yuan,

Vanishing white matter disease (VWMD) is an autosomal recessive genetic disease characterized by progressive loss of white matter in both cerebral hem...


Male Urethral Diverticulum With Stones Presenting As Acute Urinary Retention: A Case Report

By Syed Muhammad Nazim, Roshane Shahid Rana, Kaleem Khan,

Urethral diverticulum is an outpouching of urethral wall communicating with its lumen. Acquired male urethral diverticulum is a rare entity and arises...


Peripheral Odontogenic Keratocyst of Buccal Mucosa: A Case Report

By VEENA KRISHNAN, Philips Mathew, Parvathy Chitran,

The odontogenic keratocyst is a developmental cystic lesion of jaw bones. There is on-going debate about the pathogenesis of this entity.  Odontogeni...


Thymic Seminoma with Regressive Changes Obscured by Granulomatous Reaction

By Ayse Nur AKATLI, Emine Samdanci, Muhammet Reha Celik, Saadet Alan, Hakki Ulutas, Nusret Akpolat,

Primary thymic seminoma is an exceedingly rare tumor. There are few case reports about mediastinal thymic seminoma accompanied by secondary changes. W...


Impaction of Intragastric Balloon: A Rare Complication

By Ghulam Mujtaba, Rida Zehra, Fizra Balkhi, Numra Shaikh,

Non-surgical interventions for weight loss are being used more commonly and one of the emerging endoscopic bariatric therapies is the insertion of Int...


Renal clear cell carcinoma with unknown primary: is it real entity or just hypothesis?

By Yunus Emre Boru, Osman Sutcuoglu, Kubra Caliskan, Pinar Uyar Gocun, Ozan Yazici,

Renal cell carcinoma (RCC) is a common type of cancer, and about 25% of patients are diagnosed at an advanced stage. Bone metastasis is common in RCC,...


What about the cytokınes for the etıology of ıdıopathıc granulomatous mastıtıs?

By Coskun Cakir, Ali Emre Nayci, Ekrem Ferlengez, Mert Guler, Ufuk Oguz Idiz,

Objective: In this study, we aimed to investigate the roles of cytokines in the etiopathogenesis of Idiopathic Granulomatous Mastitis (IGM). Design...


Locally Aggressive Mixed Epithelial and Stromal Tumour of Kidney Leading To Nephron Loss

By Mohammad Shoaib, Imran Khan Jalbani, Zeeshan Uddin, Ahsan Rafi, Farhat Abbas,

Mixed epithelial and stromal tumour is a rare benign renal tumour. It is mainly found in perimenopausal women. We present a case of a 42-year female w...


Treatment of Severe Congenital Scoliosis with Type ІI Respiratory Failure: A Case Report

By Yingping Ma, Yonggang Wang, Xinman Dou, Fengguang Yang, Li Zhang, Xuewen Kang,

We report a case of a 14-year girl with severe congenital scoliosis (CS) and type ІІ respiratory failure (RF), who underwent preoperative halo-gravi...


Prenatal Identification and Confirmation of Jacobsen Syndrome: a Series of Four Cases

By Shilin Zhong, Yuqing Deng, Liping Xue, Ru Li,

Jacobsen syndrome (JBS) is a rare contiguous gene disorder caused by partial deletion of the distal part of the long arm of chromosome 11. Only a few ...


Early Results of Comparison of Hydrophilic Anatomical Mesh And Polypropylene Mesh For Laparoscopic Total Extraperitoneal (TEP) Inguinal Hernia Repair

By Mikail Uyan, Ismail Alper Tarim,

Objective: We aimed to compare the results, feasibility and effectiveness of laparoscopic total extraperitoneal (TEP) hernia repair made using anatomi...


An Evaluation of Rising Cesarean Delivery Rates According to Robson Classification at a University Hospital in the Black Sea Region of Turkey: Our 13-Year Experience

By Seda Keskin, Deha Denizhan Keskin, Sedat Bostan,

Objective: To analyze cesarean deliveries using the Ten Group Classification System (TGCS) for reducing cesarean rates. Study design: Cross-section...


Le Fort Partial Colpocleisis: A feasible treatment option in pelvic organ prolapse surgery not as a last resort

By Deha Denizhan Keskin, Seda Keskin,

Objective: To evaluate the safety and effectiveness of Le Forte Partial Colpocleisis (LFPC) in the surgical treatment of pelvic organ prolapse (POP) a...


Myoclonic astatic resistant epilepsy and disproportionate overgrowth carrying a duplication in 2q13 and deletion in the 6p21.32 chromosomal regions

By Sevim Türay, Recep Eroz, Ebru Karagun,

Copy number variants have been increasing due to a rise in the availability of array comparative genomic hybridization, which occupies an important pl...


Mini Anterior Incision Is Better Than The Conventional Incision In Thyroid Operations

By Mustafa Ömer Yazıcıoğlu, Servet Kocaoz, Birol Korukluoglu,

Objective: We aim to analyze  the results of mini anterior incision compared to conventional Kocher’s incision in total thyroidectomy Study Desi...


Colonic Obstruction Secondary to Phytobezoar Caused By Vitex Agnus-Castus Seeds: A Case Report

By Erkan Somuncu, Ismail Alp Solak,

Plant seeds of Vitex agnus-castus (chaste berry) are known for benefits in reproductive health and also reduce bloating, depression, headache, and con...


HLA-B51 Impact on Clinical Symptoms in Behçet's Disease

By Melih Pamukcu, Tugba Izci Duran, Mehmet Derya Demirag,

Objective: To investigate the influence of HLA-B51-positivity to clinical manifestations of Behçet’s disease (BD). Study Design: Retrospective s...


Neoadjuvant Immune Checkpoint Inhibitors In Non-Small Cell Lung Cancer

By Chongxiang Xue, Huijing Dong, Ying Chen, Xingyu Lu, Shuyue Zheng, Huijuan Cui,

Lung cancer is the leading cause of cancer related death worldwide. A meta-analysis was conducted to assess the benefits and risks of neoadjuvant immu...


Frequency and Outcome of Retinopathy of Prematurity at Tertiary Care Hospital In Pakistan

By Muhammad Amer Awan, Aqdus Haq, Fiza Shaheen, Shahid Nazir, Shehla Choudhry,

Objective: To describe the frequency and outcome of Retinopathy of prematurity (ROP). Design : Observational study. Place and Duration of Study...


The case with short stature and intellectual disability caused by a novel 2q12 duplication

By Pınar Kocaay, Ahmet Cevdet Ceylan, Derya Tepe,

Copy-number variation (CNV) is a kind of malfunction of DNA polymerase to produce extra genetic material which leads to more number of repeats in gene...


Berardinelli-Seip Congenital Lipodystrophy – A Case Report & Review of Literature

By Atif Munir, Miqdad Haider, Aijaz Zeeshan Khan Chachar,

Berardinelli-Seip Congenital Lipodystrophy (BSCL), also known as Congenital generalized lipodystrophy,  is a genetic disorder where there is absolute...


Association of c-reactive protein/albumin, procalcitonin/albumin, platelet/lymphocyte and lymphocyte/monocyte ratio with mortality in hospitalized COVID-19

By Deniz çekiç, Kubilay Issver, Ahmed Cihad Genc, Selcuk Yaylaci, Ahmed Bilal Genc, Ali Tamer,

Objective: The present study aims to investigate and compare complete blood count and biochemistry parameters such as C-reactive protein/albumin (crp/...


Study of Unilateral Extrapedicular and Bilateral Pedicle Approach Percutaneous Kyphoplasty for Osteoporotic Vertebral Compression Fracture

By Hao He, Yi Tan, Shixi Yang, Chun Zhang, Xiaojun Luo,

Objective: To study the efficacy and complication of unilateral extrapedicular approach (UEA) and bilateral pedicle approach (BPA) percutaneous kyphop...


Retrospective Analysis of 224 Patients With Percutaneous Endoscopic Gastrostomy

By Gokhan Yılmaz, Yusuf Tanrikulu, Beslen Goksoy,

Objective: To discuss the indications, early and late complications in 224 patients who underwent Percutaneous Endoscopic Gastrostomy (PEG) procedure ...


Comparison of contrast-enhanced versus non-enhanced helical computed tomography in the diagnosis of acute appendicitis: A meta-analysis

By Yuhao Chen, Jushun Yang, Ruochen Cong, Meirong Wang, Jing Xiao, Jianfeng Zhu, Ying He, Bosheng He,

We aimed to compare the performance of contrast-enhanced versus non-contrast-enhanced helical computed tomography (CT) for acute appendicitis. A syste...


Can an inferior calcar stabilising anti rotation screw improve stability in unstable A2 Inter trochanteric fractures when fixed with a Dynamic Hip screw?

By Zaid Mohammed Al-ani, Santosh Bindumadhavan, Khalid Sharif, Vijay Killampali,

Objectives: Hip fractures are the most common cause of Orthopedic admissions in the UK. Inter trochanteric fractures are the most common type.   ...


LIVER TRANSPLANTATION IN HIV POSITIVE PATIENT: FIRST REPORT FROM PAKISTAN

By Abdul Wahab Dogar, Kaleem Ullah, Shams Uddin, Hafiz Bilal Ahmed,

Human Immunodeficiency Virus (HIV) is one of the gravest health challenges worldwide in the present era, as it has been for the past four decades. HIV...


Importance of HALP Score in Breast Cancer and its Diagnostic Value in Predicting Axillary Lymph Node Status

By ALİ DURAN, Huseyin Pulat, Ferhat Cay, Ugur Topal,

Objective: We examine the diagnostic value of the haemoglobin, albumin, lymphocyte and platelet (HALP) score in predicting axillary lymph node (ALN) i...


Comparison of Complication Rates Of Different Gastrectomy Techniques of Gastric Cancer In Enhanced Recovery After Surgery Protocol: A Systematic Review And Meta-Analysis

By Zhiming Chen, Hui Xue, Hua Yuan, Jia Wang, Qiuchen Wang, Xiuying Zhang,

The purpose of this study was to analyze the postoperative complications of different gastrectomy methods, provide guidance for the development of Enh...


Hearıng Loss after the Fırst and Low Dose Admınınstratıon of Cısplatın: A Case Report

By Atila Yildirim, Evren Fidan, Feyyaz Ozdemir,

Cisplatin is a commonly used antineoplastic drug that is effective against different types of tumors. Nephrotoxicity, neurotoxicity and ototoxicity co...


Sternal Fractures in Blunt Chest Trauma: Retrospective Analysis Of 330 Cases

By Hasan Kara, Aysegul Bayir, Selim Degirmenci, Huseyin Yildiran, Mehmet Ertugrul Kafali, Ahmet Ak,

Objective: To analyse the range of injuries associated with sternal fractures and their clinical features and outcomes.  Study Design: Retrospecti...


Raoultella species associated sepsis in children: A Case series at a tertiary hospital, Karachi

By Falak Abro, Asma Sherazi, Sara Fatima, Ali Saleem,

Objective: To describe the clinical outcome and management options of gram-negative Raoultella species reported at a tertiary care pediatric hospit...


Leiomyosarcoma of inferior vena cava in an immunocompetent young-adult female patient: A case report

By João Filipe Gomes, Inês Vieira, Jorge Miguel Bastos Mendes, David Donaire, Rui Almeida,

Leiomyosarcoma of inferior vena cava is an extremely rare malignancy originating from the smooth muscle of the vessel wall, with only a few hundred ca...


Laparoscopic Gastro-Jejunostomy: An Ideal Solution To The Problem Of Gastric Outlet Obstruction Post-Corrosive Intake?

By Mahmood Ayyaz, Faraz Mahmood Ayyaz, Usman Ismat Butt, Muhammad Umar Warraich, Wasim Hayat Khan, Muhammad Waris Farooka,

Objective: To evaluate the outcome of Laparoscopic Gastro-jejunostomy in patients presenting with Gastric Outlet obstruction secondary to Corrosive...


Takotsubo like cardiomyopathy with concomitant pheochromocytoma: a rare presentation

By Pirbhat Shams, Intisar Ahmed, Sabeeh Siddique, Farhat Abbas, Aamir Hameed Khan,

Pheochromocytoma classically presents with headache, diaphoresis, palpitations and raised blood pressure. Rarely, it manifests as cardiomyopathy. Here...


A Case of Neuromyelitis Optica with Systemic Lupus Erythematosus

By Haris Majid Rajput, Waleed Shahzad, Muhammad Hassan, Mazhar Badshah, Tehmina Inayat,

Neuromyelitis Optica (NMO) is a rare, idiopathic, autoimmune demyelinating disease of central nervous system (CNS) having a relapsing course. It consi...


Laparoscopic management of intestinal obstruction due to a tight muscular cuff following transanal endorectal pull-through for Hirschsprung‘s disease.

By Vanesa Villamil, Juana María Sánchez Morote, María Josefa Aranda García, Ramón Ruiz Pruneda, María Fernández Ibieta, Juan Pedro Hernández Bermejo,

Complications of Hirschsprung’s disease‘s surgery include the general complications of any abdominal surgery, but one of the specific complication...


Spectrum of Cystic Fibrosis Conductance Regulator Gene Mutations Reported in Pakistani Descent Cystic Fibrosis Patients

By Hafsa Majid, Aysha Habib Khan, Syed Bilal Hashmi, Tariq Moatter, Asghar Nasir,

Cystic fibrosis (CF) is caused by mutations in cystic fibrosis transmembrane conductance regulator (CFTR) gene.  This study aims to determine the gen...


Systemic Immune Inflammation Index as a Reliable Disease Activity Marker in Psoriatic Arthritis

By Ayşe Bahar Keleşoğlu Dinçer, Serdar Sezer,

Objective: The aim of this study was to assess the utility of systemic immune inflammation index(SII) in predicting disease activity in Psoriatic arth...


Concomitant use of ado-trastuzumab emtansine and imatinib in a patient of CML and metastatic breast cancer: A case report

By Cengiz Karacin, Irem Bilgetekin, Fatma Bugdayci Basal, Omur Berna Oksuzoglu,

Imatinib is a CYP3A4 inhibitor, while ado-trastuzumab is a CYP3A4 substrate. Imatinib can interact with ado-trastuzumab emtansine (T-DM1) and can incr...


Hyperthyroidism presenting with coronary vasospasm: A case report

By Miao Congqing, Wang Wenyuan, Zhao Yue, Lu Dechuan, Meng Xinlong,

Hyperthyroidism is associated with a number of heart diseases, and it may aggravate previous cardiac problems or cause new ones, such as hyperthyroid ...


Predictive value of heart rate variability indexes for 2-year prognosis of patients after transcatheter aortic valve replacement

By Jianwei Zhou, Yimin Li, Jun Ji, Shu Chen, Jing Zhang, Bing Xu, Shenghu He,

To explore the prognostic value of heart rate variability (HRV) index in patients undergoing transcatheter aortic valve replacement (TAVR). Study D...


Treatment approach of acute coronary thrombosis without dissection in a bleeding patient with multiple trauma

By Gökhan YILMAZ,

Trauma is one of the causes of acute myocardial infarction (AMI). In the literature, coronary dissection or vasospasm is thought to play a role in t...


Various Risk Factors of Overweight and Obesity among Children Aged 5-16 Years

By Mashal Khan, Ajea Rani Bekhwani,

Objective: To determine the determinants of overweight and obesity among children aged 5-16 years. Study Design: Descriptive study. Study Place ...