5-Year Impact Factor: 0.9
Volume 35, 12 Issues, 2025

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Important Announcement for Trainees

"A companion journal of JCPSP (the official journal of CPSP) has been launched by the name of JCPSP Postgraduate (JCPSP PG). Submissions to JCPSP PG will be open from March 01, 2025"
For more details, Please visit https://jcpsppg.pk/.

Latest Articles
Volume 35 | Issue 5 | May 2025
Multiple Sclerosis Management in Pakistan: A Call for Comprehensive Multidisciplinary Rehabilitation Strategies

By Muhammad Farooq Azam Rathore, Sahibzada Nasir Mansoor


Differences in Clinical Efficacy of Erector Spinae Plane Block Performed at the Medial and Lateral Transverse Processes: A Randomised Controlled Trial

By Chen Chen, Hongyan Dai, Xiaoyang Jiang, Mayire Nuermaimaiti, Yanghao Ren, Tianhai Wang

ABSTRACT Objective: To compare the clinical efficacy of erector spinae plane block (ESPB) administered at the medial versus lateral aspect of the fifth thoracic transverse process (TP) apex and to investigate the potential influence of the intermuscular partitioning fascia (IMPF) on medicine diffusi...

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Comparison of Laparoscopic Cholecystectomy Outcome with Laparoscopic Versus Endoscopic Bile Duct Exploration in Elderly Patients with Cholecystolithiasis and Choledocholithiasis

By Yao Li, Tengxiao Wu, Jiayi Wang

ABSTRACT Objective: To evaluate the efficacy and safety of minimally invasive surgery in elderly patients with cholecystolithiasis and choledocholithiasis and its effects on liver function and stress response. Study Design: Comparative observational study. Place and Duration of the Study: Department...

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Laparoscopic Management of Concomitant Inguinal Hernia and Round Ligament Cysts

By An Zhang, Haisong Xu, Tingting Cao, Wenhao Huang, Gongze Peng, Tianchong Wu

ABSTRACT Objective: To evaluate and compare the efficacy and potential side effects of transabdominal preperitoneal repair (TAPP) and total extraperitoneal repair (TEP) for inguinal hernia with mesothelial cysts of uterine round ligament (IHMCURL) repair. Study Design: Observational study. Place a...

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Identification of Novel Diagnostic Markers for Atherosclerosis Using Machine-Learning Algorithms

By Yanshuang Cheng, Yang Shao

ABSTRACT Objective: To outline immune-cell infiltration and identify diagnostic genes for atherosclerosis (AS) to better understand the potential molecular processes involved in AS development. Study Design: Descriptive study. Place and Duration of the Study: Department of Cardiology, The ...

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Cascade Screening of Hereditary Angioedema in Pakistan

By Muhammad Hussain, Muhammad Omair Riaz, Mustajab Alam, Muhammad Aftab Hassan

ABSTRACT Objective: To establish cascade family screening of newly diagnosed hereditary angioedema (HAE) patients. Study Design: Cross-sectional, observational study. Place and Duration of the Study: Department of Immunology, The Armed Forces Institute of Pathology / CMH / NUMS, Rawalpindi, Pakistan...

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Comparison of Rapid Resa-Imipenem NP Test with Conventional Disc Diffusion Method for Detection of Carbapenem Susceptibility in Acinetobacter Baumannii

By Sidra Muqarrab, Irfan Ali Mirza, Sakeenah Hussain Naqvi, Asad Zafar, Adeel Hussain Gardezi, Rabia Sajjad

ABSTRACT Objective: To compare rapid Resa-Imipenem NP test with conventional disc-diffusion method for carbapenem susceptibility testing in Acinetobacter baumannii. Study Design: Cross-sectional analytical study. Place and Duration of the Study: Department of Microbiology, The Armed Forces Institute...

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Effect and Immune Mechanism of BCG-PSN on Postherpetic Neuralgia: A Single-Masked, Randomised Controlled Trial

By Yan Wu, Mi Gan, Jianbo Wu

ABSTRACT Objective: To investigate the therapeutic effect of the immune modulator Bacillus Calmette-Guerin polysaccharide and nucleic acid injection (BCG-PSN) on postherpetic neuralgia (PHN), and measure immune-related markers to elucidate the immune mechanism of BCG-PSN in treating patients with PH...

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Haemodialysis Adequacy: Ultraviolet vs. Calculated Methods

By Muhammad Anees, Noman Butt, Irfan Elahi, Muhammad Shahbaz Pervaiz, Faiqa Saeed Butt

ABSTRACT Objective: To compare measuring methods of haemodialysis adequacy; realtime urea reduction ratio (RT-URR) and realtime Kt/V (RT- Kt/V) with calculated urea reduction ratio (C-URR) and calculated Kt/V (C-Kt/V), respectively, in end-stage kidney disease (ESKD) patients. Study Design: Cross-se...


Can Lymph Node Metastasis be Predicted in Gastroenteropancreatic Neuroendocrine Neoplasias?

By Serhat Ocakli, Cengiz Ceylan, Firat Canlikarakaya, Abidin Goktas, Rumeysa Kankoc, Serdar Gokay Terzioglu

ABSTRACT Objective: To investigate the predictive factors influencing lymphatic metastasis in gastroenteropancreatic neuroendocrine neoplasm (GEP-NENs). Study Design: Observational study. Place and Duration of the Study: Department of General Surgery, Ankara City Hospital, Ankara, Turkiye, between t...

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Samatya Ratio: A Novel Prognostic Indicator for Rectal Cancer

By Ensar Cakir, Onur Olgac Karagulle, Kenan Buyukasik, Muhammed Gurluk, Ibrahim Taskin Rakici, Mert Mahsuni Sevinc

ABSTRACT Objective: To evaluate the prognostic potential of a new parameter, the Samatya ratio, calculated by dividing tumour volume by the albumin-derived neutrophil-to-lymphocyte ratio (Alb-dNLR), in rectal cancer patients. Study Design: Descriptive study. Place and Duration of the Study...

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Prediction of Occult Lymph Node Metastasis in cN0 Stage Non-Small Cell Lung Cancer Using Contrast-Enhanced CT

By Junjun Liang, Haotian Zhu, Yunjin Long, Longhuan Lu, Xin Yang, Huanwen Ding

ABSTRACT Objective: To explore the value of contrast-enhanced CT radiomics in predicting occult lymph node metastasis (OLNM) in patients with clinical N0 (cN0) stage non-small cell lung cancer (NSCLC) prior to surgery. Study Design: Descriptive study. Place and Duration of the Study: Department of R...

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The Effect of Midazolam on Remifentanil-Induced Difficulty in Mask Ventilation: A Randomised Study

By Rafet Yarimoglu, Betul Basaran

ABSTRACT Objective: To explore the impact of midazolam premedication on the difficulty of mask ventilation induced by remifentanil during general anaesthesia induction. Study Design: A prospective, randomised, double-blind study. Place and Duration of the Study: This study was conducted at Karaman T...

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Hyderabad (Sindh, Pakistan) Cancer Registry Report of Four Years (2020-2023)

By Shahid Pervez, Muhammad Rahil Khan, Ikram Din Ujjan, Nazia Mumtaz, Ejaz Alam, Huma Qureshi

ABSTRACT Objective: To collect and analyse cancer data of all malignancies from the Hyderabad Cancer Registry (HCR) for the estimation of cancer incidence (2020-2023) in various age groups and genders to identify common malignancies and any risk factors to facilitate cancer control initiative and pr...


Robotic Versus Laparoscopic Approaches to Distal Pancreatectomy: Quality Assessment of the Current Evidence

By Attam Ullah Khan, Adan Khan, Arbab Danial

ABSTRACT Pancreatic surgery, associated with technical difficulties and high complication rates, remains a challenge for surgeons. The laparoscopic approach has been shown to have benefits over the open approach; however laparoscopic distal pancreatectomy (LDP) still has its challenges. Robotic dist...

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Efficacy and Safety of Biologics and Immunosuppressants in Maintenance Therapy for Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Network Meta-Analysis

By Liangdong Zhu, Minfang Guo, Siyu Gan, Keyu Li, Yong Fu, Xia Chen

ABSTRACT Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a potentially life-threatening systemic autoimmune disease. This study aims to compare the effectiveness and safety of biologics and immunosuppressive agents in the maintenance treatment of AAV. A comprehensive search...

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Role of Intralesional Vitamin D3 in the Treatment of Cutaneous Warts

By Sabahat Shah, Seemab Khan, Noor Us Sabah

ABSTRACT Objective: To determine the effect of intralesional vitamin D3 injection in the treatment of cutaneous warts. Study Design: Quasi-experimental study. Place and Duration of the Study: Department of Dermatology, P.N.S. Shifa Hospital, Karachi, Pakistan, from May to November 2023. Methodology...

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Frequency of Disease Subsets and Spectrum of Organ Involvement and Interstitial Lung Disease Patterns in Patients of Systemic Sclerosis in Pakistani Population

By Umbreen Arshad, Muhammad Ahmed Saeed, Muhammad Rafaqat Hameed, Maryam Aamer, Shamas U Din, Hafiz Yasir Qamar

ABSTRACT Objective: To assess the frequency of disease subsets and the spectrum of organ involvement, particularly focusing on interstitial lung disease (ILD) patterns among patients with systemic sclerosis (SSc). Study Design: Observational study. Place and Duration of the Study: Institute of Rheu...

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Comparison of Clinical Outcomes of Hand-Assisted Retroperitoneoscopic with the Hand-Assisted Laparoscopic Donor Nephrectomy in Healthy Kidney Donors

By Umar Farooq, Asad Bashir, Nasrum Minallah, Fiaz Ahmad Touqeer, Zia Ul Haq Akram, Ali Asad

ABSTRACT Objective: To compare the outcomes of hand-assisted laparoscopic (HALS) and hand-assisted retroperitoneoscopic (HARS) donor nephrectomy procedures. Study Design: Descriptive study. Place and Duration of the Study: Pakistan Kidney and Liver Institute and Research Centre (PKLI & RC), Laho...


The Syndemic of Climate Change, Migration, and Mental Health: A Global Health Perspective

By Wajiha Qamar, Mehran Qayum

ABSTRACT This paper explores climate change as a catalyst for mass migration, emphasising the resulting mental health consequences for displaced populations. The tendency of social ties upon migration is substantial, as these provide both resources and stress, while the severance of such ties tends ...


Translational Biomedical Research: Challenges and Solutions of Using Animal Models

By Shahid Akhtar Akhund

ABSTRACT In translational research, utilisation of laboratory animal models contributes significantly to the understanding of human diseases, diagnostics, and therapeutics. Due to their genetic, anatomical, and physiological similarities to humans, their use allows for in vivo studies to assess the ...


Outcomes of Kangaroo Mother Care in Preterm and Low Birth Weight Newborn Babies

By Mehwish Asghar, Naseer Ahmed, Neelam Dileep, Asghar Ali Kerio, Laila Pirzado, Mubashir Hussain

ABSTRACT The objective of this study was to determine the outcomes of Kangaroo Mother Care (KMC) in preterm and low birth weight newborn babies. This prospective observational study was conducted at the Department of Paeds Medicine, People’s University of Medical and Health Sciences for Women,...


Neurological Mysteries of Behcet’s Disease Through Rheumatologist’s Eyes

By Dilara Bulut Gokten, Ridvan Mercan

ABSTRACT The aim of this study was to describe the frequency, locations, and neurological symptoms in Behcet’s patients to contribute to the understanding of the complexity of Neuro-Behcet’s disease (NBD). A total of 187 patients diagnosed with Behcet’s disease (BD) over five years...


Propofol-Induced Localised Cutaneous Allergic Reactions

By Jun-chao Dai, Jian Zhan


Successful Complete Remission with Chidamide, Venetoclax, and Azacytidine in Relapsed Acute Myeloid Leukaemia Associated with Plasmacytoid Dendritic Cells

By Guangquan Zhou, Guo Chen


Rachipagus: A Rare Occurrence of Parasitic Twins

By Arshad Khushdil, Saqib Nawaz, Sidra Malik, Muhammad Hammad Ur Rehman


Treatment of Spinal Cervical Spondylosis with ‘Uni-C’ Device and Anterior Cervical Discectomy and Decompression Fusion

By Hanlie Li, Wendong Xie, Zhiqi Zhang


Treatment of Severe Pertussis with Hyperleucocytosis in an Infant Using Exchange Transfusion: Is It the Optimal Time?

By Yao Zheng, Peisen Ruan, Hehe Chen