5-Year Impact Factor: 0.9
Volume 36, 12 Issues, 2026

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Latest Articles
Volume 36 | Issue 2 | February 2026
Artificial Intelligence and Radiomics to Enhance the Quality of Future Multidisciplinary Team Tumour Boards

By Maria Tariq, Ahmed Nadeem Abbasi


Validation of the OHIP-14 and Analysis of Gender and Treatment Differences in Oral Health-Related Quality of Life Among Pakistani Dental Patients

By Mahnoor Fatima, Mahad Bin Nadeem, Muhammad Waasay Tanweer, Muhammad Saqib, Fatima Ehsan, Javed Ashraf

ABSTRACT Objective: To compare the impact of root canal treatment (RCT) versus tooth extraction using the Urdu version of Oral Health‐Related Quality of Life (OHRQoL) in a sample of Pakistani dental patients, with special emphasis on gender differences. Study Design: A cross-sectional study. Plac...


The Effect of Preoperative Sleep Quality on Postoperative Delirium in Middle-Aged and Elderly Patients: A Clinical Setting

By Dilek Ates, Yasin Tire, Aydin Mermer, Betul Kozanhan

ABSTRACT Objective: To investigate the impact of preoperative sleep quality on postoperative delirium in adults aged 45–64 years and those aged over 65 years undergoing general anaesthesia. Study Design: An observational study. Place and Duration of the Study: Department of Anaesthesiology and...

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Artificial Intelligence-Based Digital Image Analysis for Assessing Ki67, P53, and PHH3 Expression in Glioblastoma Multiforme

By Tuba Devrim, Gamze Erkilinc, Saniye Sevim Tuncer

ABSTRACT Objective: To compare artificial intelligence (AI)-based analysis of Ki67, PHH3, and p53 immunohistochemical (IHC) biomarkers in glioblastoma multiforme (GBM) with conventional evaluations performed by experienced pathologists, and to assess the consistency and statistical significance of b...


Diagnostic Accuracy of Serum Proadrenomedullin as a Biomarker for Bacterial Sepsis in Neonates

By Afsheen Nigar, Rehma Dar, Maham Shakoor, Hafiza Tooba Aftab, Rukhsana Tumrani, Zainab Awais

ABSTRACT Objective: To determine the diagnostic accuracy of serum pro-adrenomedullin (proADM) as a biomarker of bacterial sepsis in neonates. Study Design: A cross-sectional study. Place and Duration of the Study: Departments of Chemical Pathology, Microbiology, Paediatric Emergency, and NICU, King ...


Impact of Types of Cytoreductive Surgery on Survival and Morbidity in Recurrent Epithelial Ovarian Cancer

By Akbar Ibrahimov

ABSTRACT Objective: To evaluate the survival benefits and procedural morbidity associated with iterative cytoreductive interventions in recurrent epithelial ovarian cancer (EOC), comparing outcomes across secondary, tertiary, and quaternary surgical procedures. Study Design: A descriptive analytical...


Immunopathological Profile of Angiogenesis-Related Markers in Subgroups of EGFR-Mutated Lung Adenocarcinomas

By Hong-Bo Ma, Xiao-Li Wu, Di Hu, Hui-Jie Wei, Chong Zhang, Qi Zhou

ABSTRACT Objective: To investigate the expression of angiogenesis-related markers in lung adenocarcinoma (LUAD) harbouring EGFR 19Del mutation and EGFR 21L858R mutation. Study Design: A descriptive study. Place and Duration of the Study: Department of Oncology, Chongqing University Fuling Hospital...


Implications of Fatty Acid Metabolism Genes on the Prognostic Landscape of Neuroblastoma: Integration of Genetic and Immune Profiles

By Xin Li, Hao Jin

ABSTRACT Objective: To explore the impact of fatty acid metabolism genes on the prognosis of neuroblastoma and identify potential therapeutic targets. Study Design: An observational study. Place and Duration of the Study: Department of Pathology, Tianjin Cancer Hospital, Airport Hospital, Tianjin, C...

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Expression of the Necroptosis-Related Gene MLKL Correlated with Small Cell Lung Cancer Prognosis and the Immune Checkpoint

By Yujia Hao, Guangqian Si, Ying Guo, Ruichun Lu, Pengtao Bao

ABSTRACT Objective: To identify biomarkers capable of specifically diagnosing small cell lung cancer (SCLC). Study Design: A descriptive study. Place and Duration of the Study: The Eighth Medical Centre of Chinese PLA General Hospital, Beijing, China, from January 2024 to December 2024. Methodology...

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Effect of Bilateral Complete Nasal Packing on Extubation Status after Sinonasal Surgeries

By Tooba Khanum, Sadaf Zia, Deepak Rai, Aiman Fatima Naqvi, Muhammad Shuja Farrukh

ABSTRACT Objective: To compare on-table respiratory events during extubation in patients undergoing sinonasal surgery with bilateral occlusive nasal packing versus those without nasal packing. Study Design: An experimental study. Place and Duration of the Study: Department of ENT, Head and Neck Surg...


Bioclear vs. Conventional Matrices for the Management of Anterior Black Triangles

By Han Zheng, Anna Wang, Qiong Sun, Fuhua Zhang, Lei Zhang

ABSTRACT Objective: To compare 6-month periodontal outcomes and restoration quality between Bioclear and conventional resin restorations in the management of anterior black triangles. Study Design: Randomised controlled trial. Place and Duration of the Study: Department of Periodontology, Hefei...


Antidiabetic and Antihyperlipidaemic Effects of Psidium Guajava Leaf Extract in a Diabetic Rabbit Model

By Gunesh Kumar, Ikram Din Ujjan, Nasreen Qazi, Muhammad Yaqoob Shahani, Rekha Malhi, Abdul Sattar Khan

ABSTRACT Objective: To determine the dose-dependent effects of the ethanolic leaf extract of Psidium (P.) guajava on diabetes and lipid profile in rabbits with alloxan-induced diabetes. Study Design: An analytical and experimental study. Place and Duration of the Study: Department of Pharmacology, L...


Exploring Autologous Leucocyte- and Platelet-Rich Fibrin for Wound Healing: An Innovative Alternative to Split-Thickness Skin Grafts in Resource-Limited Settings

By Madhia Sundus, Asim Aslam, Uzma Afsar, Muhammad Zubair Kiyani, Shahrukh Shah

ABSTRACT Objective: To assess the effectiveness of leucocyte- and platelet-rich fibrin (L-PRF) as a potential substitute for split-thickness skin grafting (STSG) in treating large wounds in resource-limited settings. Study Design: A cross-sectional observational study. Place and Duration of the Stud...


Comparison of Homocysteine, Zinc, and Copper Levels in Patients with Chronic Obstructive Pulmonary Disease and Healthy Controls

By Hatice Sahin, Gurkan Cikim

ABSTRACT Objective: To compare serum homocysteine, zinc, and copper levels between chronic obstructive pulmonary disease (COPD) patients and healthy controls, and to assess their associations with systemic inflammation. Study Design: A comparative cross-sectional study. Place and Duration of the Stu...

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Effects of Perioperative Transcutaneous Electrical Acupoint Stimulation on Sleep Quality after General Anaesthesia: A Systematic Review and Meta-Analysis

By Jing Ning, Cheng-Fei An, Li-Meng Li, Jia-Cheng Zhang, Tao Tan, Hua-Nan Li

ABSTRACT This meta-analysis aimed to evaluate the efficacy and safety of perioperative transcutaneous electrical acupoint stimulation (TEAS) in improving sleep quality after general anaesthesia. A comprehensive search of relevant randomised controlled trials was conducted using PubMed, Embase, Web o...


Conventional vs. Laser Haemorrhoidectomy for Symptomatic Haemorrhoids: A Meta-Analysis

By Chaoyang Wang, Yihang Liu, Ziqian Wang, Bing Li, Yiwei Cao, Li Zheng

ABSTRACT This meta-analysis aimed to compare the efficacy and safety of Diode laser haemorrhoidoplasty (DLH) with conventional haemorrhoidectomy (CH) techniques, namely Milligan-Morgan haemorrhoidectomy (MMH) and Ferguson haemorrhoidectomy (FH), for the treatment of symptomatic haemorrhoids. A searc...


Factors Influencing Undergraduate Research in a Dental College of Pakistan: Students’ Perspectives

By Saba Nosheen, Syed Ali Imdad Shah, Izza Umbrin, Nazish Ishaq, Muhammad Aamir Rafique, Haroon Abbas Ashraf

ABSTRACT Objective: To identify the motivational factors and barriers influencing undergraduate (UG) research in a dental college in Pakistan from students’ perspectives using semi-structured interviews. Study Design: A qualitative phenomenological study. Place and Duration of the Study: Nisht...


Comparison of Classical Blood Cardioplegia and Modified Del Nido Cardioplegia on Postoperative Serum Lactate Levels and Extubation Times

By Burak Tamtekin, Guler Gulsen Ersoy

ABSTRACT Objective: To compare the effects of intermittent classical blood cardioplegia and single-dose modified Del Nido cardioplegia on postoperative serum lactate levels and extubation time in patients undergoing coronary artery bypass grafts (CABG). Study Design: An observational study. Place an...


Duodenal Suspension Technique in the Laparoscopic Treatment of Congenital Duodenal Obstruction

By Shan Zeng, Bin Zhong, Peng Zhang, Fang Shu, Baojian Liao, Shuqing Wu

ABSTRACT Objective: To evaluate the effectiveness and safety of duodenum suspension in the laparoscopic treatment of congenital duodenal obstruction (CDO). Study Design: A descriptive study. Place and Duration of the Study: Department of Paediatric Surgery, Ganzhou Maternal and Child Healthcare Hosp...


The Modified Frailty Index-5 as a Predictor of Postoperative Complications Following Radical Cystectomy

By Erdinc Dincer, Orkunt Ozkaptan, Cengiz Canakci, Osman Murat Ipek, Alper Coskun, Utku Can

ABSTRACT Objective: To evaluate the predictive value of the modified frailty index-5 (mFI-5) for postoperative complications in patients undergoing radical cystectomy (RC) for muscle-invasive bladder cancer (MIBC). Study Design: A retrospective study. Place and Duration of the Study: Department of U...


Comparison of Microbial Profile, Antibiotic Susceptibility, and Mortality in Early- and Late-Onset Ventilator-Associated Pneumonia

By Sami Ur Rehman, Unaiza Saeed, Hussnain Bin Saeed, Saran Ghani, Arshad Taqi

ABSTRACT Objective: To determine the microbial profile, antibiotic susceptibility patterns, and mortality rates of early- vs. late-onset ventilator-associated pneumonia (VAP). Study Design: A retrospective cross-sectional study. Place and Duration of the Study: Surgical Intensive Care Unit, Doctors ...


Cutaneous Histoplasmosis in Patients with HIV: A Brief Review

By Maria Khan, Saba Khan, Shifa Basharat

ABSTRACT Due to advancements in diagnostic techniques and global trends in HIV, histoplasmosis—a fungal infection caused by Histoplasma (H.) capsulatum—is increasingly spreading in non-endemic areas. Although it is not considered endemic in Pakistan, research indicates that the majo...


The Educational Application of Teacher-Made Mind Maps on Students

By Shan-Qin Wang, Jin-Lan Zhou, Kai-Deng Hong, Ren-Jiao Cai, Jing Chen, Xing-Wei Zhe

ABSTRACT This study aimed to investigate the potential educational applications of teacher-made mind maps for students. This quasi-experimental study employed a single-group pre-test, post-test design and was conducted from September 2022 to April 2024. Fifty-five medical students studying symptomat...


Complete Remission in BCLC Stage C Hepatocellular Carcinoma Treated with HAIC Combined with PD-1 Inhibitors and Anti-angiogenic Therapy

By Shitao Lu, Yapan Guo, Wencong Feng, Jun Yang, Yu Yin, Zhi Li

ABSTRACT Hepatocellular carcinoma (HCC) at Barcelona-Clinic Liver Cancer (BCLC) stage C poses substantial therapeutic challenges and is typically associated with a poor survival prognosis. Triple therapy regimen comprising hepatic artery infusion chemotherapy (HAIC), programmed death receptor-1 (PD...


Medical Students’ Deaths by Suicide in Pakistan: An Analysis of Reported Cases

By Sania Mumtaz Tahir, Mohammad Umer, Ahmad Nawaz, Nazish Imran

ABSTRACT Suicide among medical students is a serious issue. To understand the pattern and risk factors associated with medical students’ deaths by suicide, a Google search was conducted for news reports in the last 10 years (2013-2023) using the keywords: medical students, suicide, death by su...


Comparison of the Effects of Medial and Lateral Erector Spinae Plane Block at the Apex of the Fifth Thoracic Vertebra Transverse Process and Exploration of the Role of Intermuscular Septum Fascia

By Ping Zhao, Qiuwan Han, Xu Qiu, Jian Zhao


Role of Bariatric Surgery in Obese Patients with Type 2 Diabetes: A New Frontier for Pakistan

By Shazia Rahim, Aabid Ul Quadir, Syed Muhammad Hassan


Complete Resection of a Large Intradural Nerve Sheath Tumour in the Lumbar Spinal Canal Using Conventional Surgery

By Jianwei Zhang, Junquan Wang, Yufeng Huang, Dong Liang


Extensive Fat Infiltration in the Lumbar Multifidus and Erector Spinae Muscles Leading to Scoliosis and Vertebral Slippage

By Jianming Zhao, Wenyuan Luo


Uncommon Associations in Duchenne Muscular Dystrophy: Coexistence of Patent Foramen Ovale and Ocular Anomalies

By Xiaojing Li, Liuyang Zhan, Xiulian Jiang


A Paediatric Storm: SARS- CoV-2 Unleashing Acute Necrotising Encephalopathy, Hepatic Failure, and Kidney Injury in a Single Strike

By Jiapei Wang, Hehe Chen