5-Year Impact Factor: 0.9
Volume 35, 12 Issues, 2025

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Latest Articles
Volume 35 | Issue 8 | August 2025
The Evolution of Nuclear Medicine from Unclear to ‘Precision’ Medicine

By Nosheen Fatima


Recovery after Hip Arthroplasty with Quadro-Iliac Plane Block: A Randomised Trial

By Muhammed Halit Satici, Mahmut Sami Tutar, Betul Kozanhan, Munise Yildiz, Ahmet Yildirim, Nuray Altay

ABSTRACT Objective: To evaluate the effectiveness of the quadro-iliac plane block (QIPB) in enhancing postoperative recovery after total hip arthroplasty (THA), using the quality of recovery-15 (QoR-15) score. Study Design: Randomised, controlled, multicentre study. Place and Duration of the Study: ...

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Phenotypic and Genotypic Association of the Duffy Blood Group Antigens (Fya, Fyb) in Healthy Blood Donors

By Sadia Ali, Fahim Akhtar, Rehan Ahmad Khan Lodhi, Nargis Sabir

ABSTRACT Objective: To determine the Duffy blood group antigens (Fya, Fyb) phenotypic and genotypic distribution among blood donors reporting in a tertiary care transfusion centre in the northern region of Pakistan. Study Design: A cross-sectional study. Place and Duration of the Study: Department o...

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Clinical Study of Hydromorphone Combined with Dexmedetomidine via Patient Controlled Analgesia for the Treatment of Acute Herpes Zoster Neuralgia

By Qingwen Yu, Jianxiong Wu, Shuangchun Peng, Changyan Huang

ABSTRACT Objective: To investigate the efficacy of hydromorphone combined with dexmedetomidine with patient-controlled intravenous analgesia (PCIA) in treating patients with acute herpes zoster (HZ) neuralgia. Study Design: Randomised controlled trial. Place and Duration of the Study: Department of...

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Breast Cancer Diagnostic Decisions from Multi-Source Data

By Ling Xu, Xiangyun Zeng, Boyuan Xing

ABSTRACT Objective: To evaluate the efficacy of support vector machines (SVM) in diagnostic decisions on the benign or malignant nature of the ultrasound Breast Imaging Reporting and Data System (BI-RADS) category 4 breast nodules in a multi-source diagnostic context. Study Design: An experimental s...

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Levels of Serum Vitamin D in Oral Lichen Planus Patients in the Twin Cities of Pakistan: A Cross-Sectional Study

By Kanwal Sohail, Maryam Rehman, Haris Ahtasham

ABSTRACT Objective: To demonstrate a probable association of the levels of vitamin D with the occurrence and severity of oral lichen planus (OLP). Study Design: A cross-sectional, descriptive study. Place and Duration of the Study: Department of Dermatology, Pak-Emirates Military Hospital, Rawalpin...

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MTHFR Gene Polymorphisms (rs1801133 and rs1801131) and Their Association with Type 2 Diabetes Mellitus and Diabetic Foot Ulcers: A Study from Karachi, Pakistan

By Saleem Ullah Atta Abro, Qamar Aziz Siddique, Iftikhar Ahmed Siddique, Zahid Miyan, Asher Fawwad, Qurratulain Saleem

ABSTRACT Objective: To explore the methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms (rs1801133 and rs1801131) and their association with type 2 diabetes mellitus (T2D) and diabetic foot ulcers (DFU). Study Design: A cross-sectional study. Place and Duration of the Study: Department of ...


Wound Management Practices in Scrotal-Confined Fournier’s Gangrene

By Tuncer Bahceci, Ozan Aydogan, Efekan Koyuncu, Kasim Emre Ergun, Mustafa Serdar Kalemci

ABSTRACT Objective: To compare real-world outcomes of different wound care strategies following surgical debridement in scrotal-confined Fournier Gangrene (FG), without inferring causality. Study Design: Observational study. Place and Duration of the Study: Department of Urology, Aydin Adnan Mendere...

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Association Between COMT rs4680 (Val158Met) Polymorphism and Academic Performance among Medical Students

By Kulsoom Farhat, Fozia Fatima, Muhammad Faisal Afridi

ABSTRACT Objective: To examine the association between the catechol-O-methyltransferase (COMT) rs4680 polymorphism — a common genetic variation in the gene, which regulates dopamine metabolism in the prefrontal cortex — and academic performance among medical students at a ...


Effect of Transumbilical Laparoendoscopic Single-Site Surgery with Extracorporeal Approach for Benign Ovarian Cysts

By Binzhou Sun, Yanyan Wang, Yanqiong Hu, Rui Li, Luqian Ge

ABSTRACT Objective: To determine the clinical effect of transumbilical laparoendoscopic single-site surgery (TU-LESS) combined with extracorporeal operation mode in the treatment of noncancerous ovarian cysts. Study Design: Observational study. Place and Duration of the Study: Department of Gynaecol...

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Hepcidin Levels and Related Biochemical Parameters in Pregnant Women with Preeclampsia

By Naim Uzun, Adem Keskin

ABSTRACT Objective: To evaluate hepcidin levels and related biochemical parameters in healthy pregnant women and those with preeclampsia. Study Design: Analytical study. Place and Duration of the Study: Erzurum Nene Hatun Maternity and Child Diseases Hospital, Erzurum, Turkiye, from October to Dec...


Sepsis-Associated Acute Kidney Injury in the Paediatric Intensive Care Unit: Frequency and Outcomes

By Anosha Muhammad Aslam, Wasif Ilyas Vohra, Ariba Siddiqui, Ezza Riaz, Qalab Abbas, Sajid Bashir Soofi

ABSTRACT Objective: To assess the frequency and short-term outcomes of padietric patients admitted with sepsis-associated acute kidney injury (S-AKI) in the paediatric intensive care unit (PICU). Study Design: A cross-sectional study. Place and Duration of the Study: Department of Paediatrics, The A...


Predicting Extracorporeal Shock Wave Lithotripsy Outcomes Using Machine Learning and the Triple-/Quadruple-D Scores

By Mucahit Gelmis, Sina Kardas, Ali Ayten, Oguzhan Cura, Serkan Gonultas, Mustafa Gokhan Kose

ABSTRACT Objective: To evaluate the predictive performance of the triple-D and quadruple-D scores integrated with machine learning (ML) models in determining stone-free outcomes after extracorporeal shock wave lithotripsy (ESWL), and to compare ML model performance and identify its key predictors in...

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Safety and Efficacy of the Mid-Calyx Access Versus the Lower-Calyx Access in Paediatric Percutaneous Nephrolithotomy (PCNL)

By Asif Khan, Akhtar Nawaz, Riaz Ahmad Khan, Nizam Uddin, Sami Ur Rahman, Kaleemullah Jan

ABSTRACT Objective: To compare the safety and efficacy of the mid-calyx access (MCA) and the lower-calyx access (LCA) in paediatric percutaneous nephrolithotomy (PCNL). Study Design: Descriptive study. Place and Duration of the Study: Department of Paediatric Urology, Institute of Kidney Disease, Pe...

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Comparison of Dexmedetomidine and Propofol for Magnetic Resonance Imaging in Children: A Meta-Analysis

By Wei Yang, Mingjun Zhu, Jun Xu, Yueyong Wang

ABSTRACT Paediatric magnetic resonance imaging (MRI) allows visualisation of internal structures in children without the use of ionising radiation. It often requires sedation to minimise patient’s movement to enhance image quality. Dexmedetomidine and propofol are widely used as sedative agent...


Association Between VEGF Gene Polymorphism and Diabetic Neuropathy Susceptibility

By Lequan Wen, Changsen Yang, Tiangang Song, Nan Guo, Lirui Tang, Haokun Tian

ABSTRACT Diabetic neuropathy is a common complication of diabetes, characterised by peripheral nerve damage that manifests as sensory loss and pain. Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis and microvascular function. The association between the rs3025039 polymo...


Early Versus Late Stoma Reversal in Children Presenting with Acute Abdomen

By Abdullah Khan, Muhammad Bilal Mirza, Nabila Talat

ABSTRACT Objective: To determine the morbidity e.g., anastomotic leakage and wound infections, in children enduring early (same-admission) vs. late (routine-interval) stoma reversal. Study Design: A quasi-experimental study. Place and Duration of the Study: Department of Paediatric Surgery Unit II, ...


Healing and Cosmetic Outcomes in Split-Thickness Skin Graft Donor Sites Using Minced Skin Grafting Across Skin Types

By Zafar Iqbal, Shumaila Rehman Dogar, Nazish Nazir Cheema, Muhammad Mustehsan Bashir

ABSTRACT Objective: To determine the effect of minced skin grafting on complete healing of the donor site and cosmetic appearance in different skin phototypes. Study Design: Case series. Place and Duration of the Study: Department of Plastic Surgery, Mayo Hospital, King Edward Medical University, ...


Predictive Factors for Multiple Sessions of Retrograde Intrarenal Surgery to Achieve Stone-Free Status

By Volkan Selmi, Mehmet Caniklioglu, Sercan Sari, Levent Isikay

ABSTRACT Objective: To investigate potential predictive factors for multiple sessions of retrograde intrarenal surgery (RIRS) to achieve stone-free status in patients with kidney stones. Study Design: A descriptive study. Place and Duration of the Study: Department of Urology, Faculty of Medicine, ...


MRI-Compatible and Cost-Effective Clipping of Breast Carcinoma Using Titanium-Based Surgical Ligating Clips

By Rana Bilal Idrees, Mariam Malik, Zeeshan Rashid Mirza, Faisal Ehsan Cheema, Jawairia Arif, Sadia Anwar

ABSTRACT The MRI compatibility, safety, and effectiveness of titanium-based surgical ligating clips (TBC) were evaluated in breast cancer patients. In a prospective study conducted at the Department of Radiology, INMOL Cancer Hospital, Lahore, Pakistan, from August 2022 to 2023, ten female patients ...


Rate, Complications, and Satisfaction of Epidural Analgesia among the Parturient Population

By Sami Ur Rehman, Aleena Kashif, Arshad Taqi, Abdul Rehman, Affan Ahmad Khan, Maryam Inayat

ABSTRACT Objective: To determine the rate of labour epidural insertion, complications, and satisfaction among the parturient population admitted to the Department of Gynaecology, Doctors Hospital and Medical Centre, Lahore, Pakistan. Study Design: A clinical audit. Place and Duration of the Study: ...


Strategic Implementation of Artificial Intelligence in Emergency Department Roster Planning: Benefits, Challenges, and Future Directions

By Bushra Qaiser Qureshi, Shahan Waheed, Rida Jawed

ABSTRACT Integrating artificial intelligence (AI) in emergency department (ED) rostering represents a significant advancement in healthcare workforce management. This study examines the transformative impact of AI-driven systems on ED staffing operations and their potential to optimise resource allo...


Evaluating Medical Educators Practices: Core Competencies and Entrustable Professional Activities (EPAs) for Healthcare Professional Educators

By Khadija Farrukh Warraich

ABSTRACT The objective of this research is to evaluate the core competencies and entrustable professional activities (EPAs) for the structured training of healthcare professional educators. A qualitative case study using the modified Delphi technique was performed at the Department of Medical Educat...


Correlation Between Cystatin-C and Interleukin-34 Expression Detection and Post-Stroke Cognitive Impairment

By Xinlei Wang, Weina Guo, Jinye Zhao, Jing Zhao, Jing Wei

ABSTRACT The aim of this study was to explore the relationship between the expression levels of Cystatin-C (Cys-C) and Interleukin-34 (IL-34) and cognitive impairment following a stroke. It was a retrospective study carried out from May 2022 to May 2024. Stroke patients were selected as research sub...


Oxidative Balance Scores in Cancer Survivors: A Nationwide Cross-Sectional Study

By Jae Hyuck Lee, In Cheol Hwang, Hong Yup Ahn

ABSTRACT Although some studies have investigated the relationship between oxidative imbalance and adverse outcomes, there is a lack of data on oxidative balance in cancer survivors. Using data of the 2013-2020 Korean nationwide surveys, this study examined the oxidative balance score (OBS) of non-su...


Environment-Conscious Imaging: Clinicians Must Lead the Change

By Farooq Azam Rathore


Cerebral Cysticercosis Manifesting 20 Years after Primary Cutaneous Disease

By Yang Cui, Bingheng Wang


Simultaneous Bilateral Carotid Artery Stenting on Elderly Patients

By Sisi Zhao, Pengfei Hu, Lingtao Tang


A Case of Solitary Pulmonary Papillary Adenoma

By Cunfu Fan, Junhong Cai


Voices in the Shadows: How Fear Stifles Innovation and Harms Mental Health in Conservative Workplaces

By Wajiha Qamar, Mehran Qayum