Impact Factor 0.711 5 Year Impact Factor 0.735
Volume 32, 12 Issues, 2022

Epub Ahead of Print

Modified Double-Tract Reconstruction in Gastrointestinal Reconstruction After Proximal Gastrectomy

By Yingying Li, Jian Wu, Ming Han, Wenbin Li, Zhibin Bi,

Objective: To determine the clinical efficacy and safety of modified double-channel anastomosis for digestive tract reconstruction in proximal gastrec...


Effects of Aerobic Exercise on Vascular Wall Thickness: A Meta-Analysis of Pre-Clinical Trials On Rat Model

By Fatima Hamza, Nudrat Nawaid Shah, Amna Aamir Khan, Sumaira Imran Farooqui, Kevin Joseph Jerome Borges,

Exercise instigates adaptations in structural as well as functional organization of the body at tissue and organ levels. However, the effect of exerci...


Risk Factors for Cytomegalovirus Infection after Hematopoietic Stem Cell Transplantation: Meta-Analysis

By Siting Wu, Li Wang, Caiyun Zhang, Chunli Wang,

ABSTRACT Cytomegalovirus (CMV) infection is the most common viral infection after hematopoietic stem cell transplantation (HSCT). However, studies ...


Effect of Tissue Fragments Remains in The Karman Cannula On the Histopathological Diagnosis of Abnormal Uterine Bleeding

By Ömer Tammo, Enes Elk, Elİf Elik, Denİzhan BayramoĞlu, SÜleyman Yildiz,

ABSTRACT The aim of this study was to histopathologically analyse the residual material in the cannula by endometrial sampling using a Carmen injec...


Introduction of Simulation Based Learning Strategy to Bridge the Theory Practice Gap in Advanced Concepts in Community Health Nursing: Lens from Students’ Perspective

By Sanam Hanif, Yasmin Nadeem Parpio,

ABSTRACT Simulation has proven to be one of the most powerful forms of enactive experience in medical sciences, which enhances the efficacy of both...


Risk Factors for Renal Involvement in Childhood Henoch-Schonlein Purpura (IGA Vasculitis)

By Shuhui Min, Xi Chen, Danfeng Wang, Xiao Lin, Guan Jiang,

ABSTRACT The study was designed to investigate the risk factors for renal involvement in children with immunoglobulin A (IgA) vasculitis. It is a h...


Root Canal Morphology of Premolars in Population of Hyderabad, Pakistan: A Cone Beam Computerised Tomographic Analysis

By Sarang Suresh, Feroze Ali Kalhoro, Priya Rani, Mahwish Memon,

  ABSTRACT Objective: To investigate the mean tooth length and root canal configuration of human maxillary and mandibular premolars in the popu...


Frequency and Outcome of Postoperative Atrial Fibrillation Following Mitral Valve Replacement for Mitral Stenosis

By Kiramat Ullah Khan, TAHIR IQBAL, Arooba Tariq, Mubeen Ali, Niaz Ali,

ABSTRACT Objectives: To determine the frequency and outcome of postoperative atrial fibrillation (POAF) in terms of in-hospital and 30-day mortalit...


Synergistic Strides: Exploring Concurrent Exercise for Type 2 Diabetes Management; a Systematic Review and Meta-Analysis

By Uroosa Amin, Qurat-ul-Ain Adnan, Tauseef Ahmad, Sumaira Imran Farooqui,

The effectiveness of concurrent exercise (CE) as an emerging approach for type-II Diabetes mellitus (T2DM) patients was evaluated through a comprehens...


A Systematic Review and Meta-Analysis on the Impact of Screen-time on the Social-Emotional Development of Children Under Five

By Areesha Ahmer, Mohammad Raza, Maha Azhar, Abdur Rahman, Jai Kumar Das, Sidra Kaleem Jafri,

Given the rising consumption of electronic media by children under five, it is crucial to study the impact of screen time (ST) on the social-emotional...


Thymosin Alpha 1 Plus Routine Treatment for The Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis

By Ailing Cao, Fanchao Feng, Xianmei Zhou,

This systemic review was conducted to assess the curative effect of thymosin alpha 1 in the acute exacerbation of chronic obstructive pulmonary diseas...


Prediction of In-Hospital Mortality After Emergency Laparotomy Using Glasgow Coma Scale, ASA Physical Status Classification and P-Possum Score

By Muhammad Asif, Saeed Bin Ayaz, Faran Hamid, Muhammad Nabeel Imran, Adnan Mehraj, Naheed Akhtar,

Objective: To determine the importance of the Glasgow Coma Scale (GCS), ASA Physical Status Classification System, and P-POSSUM score in predicting mo...


Management of Mandibular Condylar Fractures: A Comparison of Closed versus Open Reduction

By Syed Ammar Yasir, Ali Akhtar Khan, Sana Somair Waheed, Naseer Ahmad Kakar, Hamza Asif, Bisma Naeem,

Objective: To compare the closed reduction approach with open reduction (transparotid approach) in management of condylar fractures for parameters lik...


Reversion of Supra-Ventricular Tachycardia Through High Positive End-Expiratory Pressure During Mechanical Ventilation in Critically Ill Patients

By Hong-bo Wu, Shou-Yin Jiang, Shan-xiang Xu, Xiao Lu,

The Valsalva manoeuvre is widely recognised for its effectiveness in reverting supra-ventricular tachycardia (SVT) in patients with good coordination....


Pain Management in A Tertiary Care Setup: Assessing Patient Satisfaction and Pain Relief

By Muhammad Rashid Iqbal, Aijaz Ali, Mudassar Iqbal, Syed Majid Waseem, Moazam Ali, Muhammad Tahseen Talib,

The aim of this study was to assess the patient satisfaction and pain relief before and after interventions for chronic pain in a tertiary care pain c...


Effect of Blood Component Transfusion on Coagulation Function in Postpartum Haemorrhage

By Tianming Yan, Huiqun Xu, Fengling Li, Bili Zhang, Qiang Hong, Yijing Wang,

Postpartum haemorrhage (PPH) is a serious complication of pregnancy. In this study, patients with PPH were treated with blood component transfusion, a...


Application of Multi-Slice Spiral CT Renal Angiography Combined with Intraoperative Ultrasound in Laparoscopic Partial Nephrectomy

By Tao Ma, Wentao Wang, Ke Zhang, Wenzeng Yang, Zhen-yu Cui,

This study aimed to evaluate the clinical significance of multi-slice spiral CT renal angiography combined with intraoperative ultrasound in laparosco...


RENAL Nephrometry Scores and Perioperative Outcomes in Open Partial Nephrectomy

By Nadeem Bin Nusrat, Sana Kundi, Assad Ur Rehman, Nauman Zafar, Sarmad Imtiaz Bajwa, Saira Imtiaz,

Objective: To evaluate the efficacy of RENAL nephrometry scores in guiding open partial nephrectomy for renal malignancies and comprehends perioperati...


Preoperative Ultrasound Guided Marking, a 2 View Mammogram and Per-operative Use of Image Intensifier: A Cost-Effective Technique in Clipped Non-Palpable Breast Cancer Lesions to Achieve Adequate Surgical Margins

By Amna Masud, Huma Majeed Khan, Eisha Tahir, Anam Waseem, Hafsa Ahmad, Rabia Ikram,

Objective: To measure the effectiveness of localization and removal of impalpable target lesions without compromising patient safety in a resource-lim...


Positioning for Emergency Laparoscopic Splenectomy for Traumatic Splenic Rupture

By Jun Hong Haung, Qiang Zhi Haung, Fei Ruo Xiong, Cheng Xing Meng, Ju Zhang,

Objective: To determine whether the right lateral decubitus or supine position is superior for emergency laparoscopy for traumatic splenic rupture. ...


Positioning for Emergency Laparoscopic Splenectomy for Traumatic Splenic Rupture

By Jun Hong Haung, Qiang Zhi Haung, Fei Ruo Xiong, Cheng Xing Meng, Ju Zhang,

Objective: To determine whether the right lateral decubitus or supine position is superior for emergency laparoscopy for traumatic splenic rupture. ...


Positioning for Emergency Laparoscopic Splenectomy for Traumatic Splenic Rupture

By Jun Hong Haung, Qiang Zhi Haung, Fei Ruo Xiong, Cheng Xing Meng, Ju Zhang,

Objective: To determine whether the right lateral decubitus or supine position is superior for emergency laparoscopy for traumatic splenic rupture. ...


Association of Androgenetic Alopecia with Metabolic Syndrome

By HINA FAROOQ QURESHI, Aisha Akhtar, Asmat Ullah, Syeda Sakina, Sania Irum, Nasira Nasr,

Objective: To determine the association of androgenetic alopecia with metabolic syndrome in either. Study Design: Descriptive study. Place and D...


Coronary Artery Bypass Grafting in Young Adults

By Hina Inam, Abdul Ahad Sohail, Aimen Aamir, Kaleem S Ahmed, Narmeen Asif, Syed Shahabuddin Sharfuddin,

Objective: To evaluate the risk factors for early onset of coronary artery disease and assess the preoperative presentation, perioperative course, sur...


The Role of Edmonton Frailty Index in Determining the Postoperative Complications in Elderly: A Prospective Observational Study

By Seyda Canli, Cem Ece, Fulya Yılmaz Barut,

Objective: To explore the effect of Edmonton Frailty Index on the determination of postoperative complication and mortality rates in patients over 65 ...


High-Risk Influential Factors for Cardiovascular Diseases Among Young Adults

By Xiaowei Wang, Tianhong Yang, Jinxiu Liu,

The aim of this study was to compare high-risk influential factors for cardiovascular diseases among different young adults. It was a retrospective st...


Diagnosis of Bruxism in Adults; A Systematic Review

By Hina Zafar Raja, Muhammad Nasir Saleem, Maryam Mumtaz, Fizza Tahir, Usman Iqbal, Alina Naeem,

Bruxism is a centrally mediated neurological para-functional movement disorder encompassing clenching, and grinding of teeth, or thrusting and bracing...


Paediatric Pain Assessment and Perioperative Pain Management: A Survey of Practice in Teaching Hospitals in two Provinces of Pakistan

By Bushra Salim, Muhammad Ali Asghar, Shemila Abbasi, Saima Rashid, Khalid Maudood Siddiqui, Fauzia Anis Khan,

Objective: The primary objective was to map the practice of paediatric perioperative pain assessment and management among consultant anaesthetists wor...


Oxidative balance scores in adults with suicidal ideation: A nationwide Korean survey

By Jaehyuck Lee, Ki Dong Ko, In Cheol Hwang, Hong Yup Ahn,

This cross-sectional study investigated the relationship between oxidative balance (OB) scores and suicidal ideation among Korean adults. Data from 17...


Effects of PCSK9 Inhibitors On Glucose Metabolism in Hyperlipidaemia Patients: A Meta-Analysis

By Yujie Bai, Miao Hu, Jiayan Zhang, Ling Zhou,

This review assessed the impacts of PCSK9 inhibitors on glucose metabolism in patients with dyslipidaemia. A comprehensive search was conducted using ...


Prognostic Significance of CD4+ Tumour Infiltrating Lymphocytes in Patients with Non-Small Cell Lung Cancer Receiving PD-1/PD-L1 Inhibitors Therapy

By Qi-ming Zheng, Yuan-yuan Li, Ye-peng Wang, Guo-xiang Li, Zhi-gang Sun, Min Zhang,

CD4+ tumour infiltrating lymphocytes (TILs) have been found to produce a marked effect in anti-tumour immunity. In the study, the authors explored t...


Effectiveness of Cardiac Rehabilitation On Health-Related Quality of Life in Coronary Artery Disease Patients in Low and Middle-Income Countries

By ALIYA HISAM, Zia Ul Haq, Zohaib Khan, Sumaira Masood, Jill P Pell, Patrick Doherty,

This meta-analysis of published studies was calculated to determine the effectiveness of cardiac rehabilitation (CR) in terms of health-related qualit...


Sevoflurane Anaesthesia Increases the Risk of Perioperative Acute Kidney Injury than Propofol: A Meta-analysis of RCTs

By Mingjuan Li, Wenli You, Xiaosa Chi, Maomao Nie, Anmu Xie,

Sevoflurane has been suggested to lower the incidence of acute kidney injury (AKI) after heart surgery compared to intravenous anaesthetics. However, ...


Establishing a Newborn Screening Program: A Success Story from a Low-Resource Setting

By HAFSA RAIS, Lena Jafri, Sibtain Ahmed, Khadija Nuzhat Humayun, Salman Kirmani, Aysha Habib Khan,

The purpose of this communication was to assess the clinical effectiveness of an NBS program for congenital hypothyroidism (CH) in a tertiary care...


STN and GPi -Deep Brain Stimulation for Primary Cervical Dystonia

By Wei Tian, Guanyu Zhu, Shiying Fan, Fangang Meng, Anchao Yang, Jianguo Zhang,

Objective: To evaluate the safety and efficiency of deep brain stimulation (DBS) in the treatment of primary cervical dystonia (CD) and to compare the...


Efficacy and Safety of Biologics and Immunosuppressants in Maintenance Therapy for Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Network Meta-Analysis

By Liangdong Zhu, Minfang Guo, Siyu Gan, Keyu Li, Yong Fu, Xia Chen,

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a potentially life-threatening systemic autoimmune disease. This study aims ...


Association Between C-Reactive Protein and Suicidal Ideation: A Large-Scale Cross-Sectional Study

By In Cheol Hwang, Hong Yup Ahn, Yujin Park,

Studies of C-reactive protein (CRP) levels and suicidal behaviours have shown inconsistent results previously. This study investigated the relationshi...


Clinical Efficacy of Ganglioside Combined with Methylprednisolone in the Treatment of Spinal Cord Injury and its Effect on Inflammatory Response and Oxidative Stress Factors

By Dongliang Ren, Hui Li, Xiangdong Liu, Meihua Wang,

Objective: To determine the clinical efficacy of monosialotetrahexosylganglioside combined with methylprednisolone in treatment of spinal cord injury ...


The Effectiveness of Nicorandil in Heart Failure Patients: A Comprehensive Review and Meta-Analysis

By Tongge Mu, Kaixuan Tang, Yan Sun,

This meta-analysis aims to evaluate the effectiveness of nicorandil in treating heart failure by synthesizing evidence from diverse studies. This stud...


Robotic Versus Laparoscopic Approaches to Distal Pancreatectomy: Quality Assessment of The Current Evidence

By Attam Ullah Khan, Adan Khan, Arbab Danial,

Pancreatic surgery, associated with technical difficulties and high complication rates, remains a challenge for surgeons. The laparoscopic approach ha...


Long-Term Clinical Outcomes of the Transcatheter Aortic Valve System for Aortic Valve Stenosis

By Zijia Wu, Lulan Gao, Lei Chen, Zhihai Lin,

Objective: To evaluate the clinical safety and efficacy of the self-expanding transcatheter aortic valve system in Chinese patients with severe aor...


Fıstulectomy and Prımary Sphıncteroplasty (FIPS) for Transsphıncterıc Fıstula

By Ahmet Cihangir EMRAL, Merter Gulen, Bahadir Ege,

Objective: To evaluate the results of patients treated with fistulectomy and primary sphincteroplasty for uncomplicated perianal fistula. Study Des...


Peripheral Nerve Block Combined with Low-Dose General Anesthesia in Elderly Patients Receiving Hip Arthroplasty

By Ying Zhu, Yulin Liu, Hong Fu,

The study assessed the effectiveness and safety of nerve block combined with low-dose general anaesthesia in elderly hip arthroplasty patients, conduc...


COVID-19 Associated Neuromuscular Disorders-An Electrodiagnostic perspective Study

By Muhammad Tawab Khalil, Uzma Akhlaque, Umer Younis, Sana Arshad,

This cross-sectional study aimed to describe electro-diagnostic findings of neuromuscular disorders (NMD) associated with COVID-19 infection. Patients...


Effects of Small Dose Esketamine on Postoperative Analgesia and Sleep Quality in Patients with Total Hip Replacement

By Qiufeng Wei, Sisi Feng, Weixin Dai, Chengxin Lin, Wen Zheng He,

Objective:To determine the effect of esketamine in patient-controlled analgesia after hip replacement on postoperative pain and improve sleep quality ...


Outcome of Kangaroo Mother Care in Preterm And Low Birth Weight Newborn Babies

By Dr Mehwish Asghar, Dr Naseer Ahmed, Dr Neelam Dileep, Dr Asghar Ali Kerio, Dr Laila Pirzado, Dr Mubashir Hussain,

The objective of this study was to determine the outcomes of Kangaroo Mother Care (KMC) in preterm and low birth weight newborn babies. This prospecti...


Postgraduate Training in Prosthodontics: Residents’ and Supervisors’ Perspectives on Current Training - A cross-Sectional Study

By Syed Murtaza Raza Kazmi, Fakeha Azhar Syed, Muhammad Sadiq Billoo, Taimur Khalid,

Objective: To identify postgraduate (PG) prosthodontic trainees’ and supervisors’ introspective views regarding prosthodontic education and clinic...


Abnormal Brain Function in Systemic Lupus Erythematosus: A Meta-Analysis of Resting-State Functional Magnetic Resonance Imaging

By Xi Sun, Dongmei Fu, Yuting Mao, Zuanfang Li, Yinghong Lin, Jiaqiu Lin,

This meta-analysis investigated the neurophysiological underpinnings of systemic lupus erythematosus (SLE) by examining resting-state functional magne...


Frequency and Patterns of Multidrug Resistant Organisms among Ventilated Patients During The Coronavirus Disease-19 Pandemic

By Faiza Rezwan, Tazeen Fatima, Farheen Ali, Muhammad Nadeem, Nawal Salahuddin,

Objective: To determine the frequency of multidrug-resistant (MDR) bacterial isolates in respiratory specimens obtained from ventilated patients admit...


Treatment Outcome of Hematopoietic Stem cell Transplant in Fanconi Anaemia

By Hashim Khan, Prof Tariq Ghafoor, Tariq Azam Khattak, Nighat Shahbaz, Munazza Nabi Awan, Awais Siddiq,

Objective: To determine the outcome of Hematopoietic stem cell transplant (HSCT) in Fanconi anaemia patients. Study Design: Retrospective Study. ...


Antimicrobial Efficacy of Nanoparticle-Coated Gutta Percha: A Systematic Review

By Samira Adnan, Abishek Lal, Maham Muneeb Lone, Jamshed Ahmed, Isma Sajjad, Huma Shareef, Muhammad Sohail Zafar,

This systematic review aimed to evaluate the use of different nanoparticles for their ability to impart antimicrobial properties to conventionally ine...


The Efficacy and Safety of Trastuzumab in The Metastatic Breast Cancer

By Xinli Wang, Yan Xue,

The aim of this study was to explore the efficacy and safety of Trastuzumab Deruxtecan (T-DXd) in metastatic breast cancer (mBC). It was an retrospect...


Effectiveness of Early Feeding versus Conventional Protocol after Stoma Reversal in Adult Surgical Practices

By Sajid Ali, Faheem Khan, Saman Hafeez, Zaka Ullah Jan, Mian Tauseef Uddin,

Objective: To compare the effectiveness of early feeding and conventional feeding protocol after stoma reversal in adult surgical practices. Study ...


Unlocking precision enhancing prostate cancer detection and reducing unnecessary biopsies with combined Prostate-specific antigen density (PSAD) and PI-RADS score

By Nurullah Hamidi, Tuncel Uzel, Aykut Demirci, Halil Basar,

Objective: To determine clinically significant prostate cancer (csPCa) detection rate by combining the Prostate-specific antigen density (PSAD) and Pr...


Stem Cell Mobilization failure in Auto HSCT and Its Factors, A Single Centre Experience

By Dr Irsa Hidayat, Dr Mehreen Ali Khan, Dr Munazza Nabi Awan, Dr Awais Siddiq, Dr Sahla Riaz, Dr Qudrat Ullah,

Objective: To determine the mobilization failure rate and identify its associated factors in this part of world in order to identify patients at risk ...


Deep Vein Thrombosis as a Harbinger of Malignancy in the Emergency Department

By Mehmet Cihat Demir, Kudret Selki,

Objective: To determine whether malignancy was discovered within one year of follow-up in patients diagnosed with deep vein thrombosis (DVT) in the em...


Incisional Hernia Repair: Metanalysis on Laparoscopic and Open Surgical Repair

By Rosario Vecchio, Serena Scilletta, Eva Intagliata,

Despite the benefits of laparoscopic surgery, routine laparoscopic treatment of incisional hernia remains controversial. The aim of this meta-analysis...


Correlation of Peripheral Blood CD4/CD8 Ratio with Efficacy and prognosis in Patients with Non-Small Cell Lung Cancer Receiving PD-1/PD-L1 Inhibitors

By Qi-ming Zheng, Yuan-yuan Li, Ye-peng Wang, Guo-xiang Li, Zhi-gang Sun, Min Zhang,

The aim of this study was to investigate the predictive role of peripheral blood CD4/CD8 ratio in patients with non-small cell lung cancer (NSCLC) tre...


Paediatric Early Warning Score to Detect Deterioration in Paediatric Patients at a Tertiary Care Hospital of a Developing Country: A Validation Study

By Wasif Ilyas Vohra, Ayaz Ur Rehman, Anosha Aslam, Salman Khan, Qalab Abbas,

Objective: To test the validity of the paediatric early warning score (PEWS) and to identify the patients with deteriorating clinical conditions who w...


Role of Humor in Nursing Pedagogy

By Bibi Hajira Irshad Ali Wali, Nafisa Iqbal Bardaie,

Objective: To explore nursing educators' perceptions about using humor as a teaching strategy in the classroom setting. Study Design: Qualitati...


Outcomes of Auto Hematopoietic Stem Cell Transplant in Lymphomas, a Single Centre Study

By Dr Irsa Hidayat, Dr Mehreen Ali Khan, Dr Munazza Nabi Awan, Dr Awais Siddiq, Dr Noor Shamim, Dr Hashim Khan,

Objective: To determine the outcomes of auto hematopoietic stem cell transplant in lymphoma patients in terms of overall survival, disease free surviv...


Correlation of HER2 Expression in Gastric Carcinoma with Clinicopathological Parameters in the Omani Population

By ASIM QURESHI, Hana Al Julandana, Sara Al Barkhati, Ahmed Al Ghaithi, Asem Shalaby,

This retrospective study was conducted to determine the relation between Her2 expression and the clinicopathological and prognostic characteristics of...


The Association Between Facial Aging and Bone Mineral Density: A Mendelian Randomization Study

By Yabo Wang, Chao Zhen, Ziyu Wang, Lu Zhang, Yunzhen Chen,

This article aimed to assess the causative association between facial aging and bone mineral density (BMD) using Mendelian randomization (MR). In this...