Journal of College of Physicians and Surgeons Pakistan (JCPSP), is the prestigious, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.

The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.

Important Announcement for Authors

"As a large number of case reports are awaiting publication, JCPSP has decided to stop acknowledging Case Reports for a certain period of time until the backlog is cleared. Therefore, case reports are regretted from processing".

Latest Articles
Volume 31 | Issue 9 | September 2021
Radiofrequency Catheter Ablation Method or Stereotactic Body Radiotherapy in the Treatment of Ventricular Tachycardia

By Yasemin Benderli Cihan

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Diagnostic Accuracy of Markers of Insulin Resistance (HOMA-IR) and Insulin Sensitivity (QUICKI) in Gestational Diabetes

By Athar Iqbal Paracha, Zujaja Hina Haroon, Muhammad Aamir, Afshan Bibi

ABSTRACT Objectives: To determine the diagnostic accuracy of HOMA-IR, and QUICKI in diagnosing gestational diabetes mellitus (GDM) considering oral glucose tolerance test (OGTT) as gold standard. Study Design: Cross-sectional analytical study. Place and Duration of Study: Department of Chemical Path...

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Association of Therapeutic Dose of Valproic Acid and Plasma Glycine Levels in Epileptic Patients

By Shakeel Ahmad, Muhammad Aamir, Sobia Irum Kirmani, Zujaja Hina Haroon, Muhammad Usman Munir, Usama Bin Khalid

ABSTRACT Objectives: To determine the frequency of hyperglycinemia in epileptic patients taking valproic acid (VPA); and the correlation between therapeutic dose of valproic acid and plasma glycine levels in epileptic patients. Study Design: Observational, cross-sectional study. Place and Duration o...

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Four Different Apparent Diffusion Coefficient Measurement Methods in Breast Masses

By Betul Duran, Burcin Agridag Ucpinar

ABSTRACT Objective: To compare the effect of different quantification methods of ADC values in the evaluation of breast lesions and compare contralateral normal breast tissue ADC value by calculating ADC ratios. Study Design:  Descriptive study. Place and Duration of the Study: Sisli Etfal Trai...

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The Relationship between PI-RADS Categories and Incidental Findings in Multiparametric Prostate MRI

By Suna Sahin Ediz, Nesrin Gunduz

ABSTRACT Objective: To find the frequency and significance of extraprostatic incidental findings (ep-IFs) during multiparametric-magnetic prostate resonance imaging (mp-MRI), and compare them with prostate imaging reporting and data system (PI-RADS) outcomes. Study Design: Analytical study. Place &...

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Effect of Exenatide Therapy on Platelet Function in Type 2 Diabetes Mellitus

By Murat Çalapkulu, Muhammed Erkam Sencar, Ilknur Ozturk Unsal, Davut Sakiz, Mustafa Ozbek, Erman Cakal

ABSTRACT Objective: The purpose of the present study was to determine the effects of exenatide treatment on platelet function in type 2 diabetes mellitus (DM) patients. Study Design: Case-control observational study. Place and Duration of Study: University of Health Sciences, Diskapi Yildirim Beyaz...

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Factors Associated with Seroconversion of Hepatitis C Virus in End Stage Renal Disease Patients

By Muhammad Anees, Nosheen Sarwar, Sajad Ahmad, Irfan Elahii, Fazal e Mateen

ABSTRACT Objective: To determine patient and dialysis services-related factors associated with seroconversion of hepatitis C virus (HCV) in hemodialysis (HD) patients. Study Design: Cross-sectional study. Place and Duration of Study: Department of Nephrology, Mayo Hospital, King Edward Medical Uni...

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Can the Additional Dose Requirement be Determined before the Seventh Day to Successfully Treat Tubal Ectopic Pregnancy with a Single-dose Methotrexate Protocol?

By Burak Akselim, Süleyman Serkan Karaşin, Yeliz Acar Sabır

ABSTRACT Objective: To investigate the relationship of beta-hCG changes between the first, fourth and seventh days as a predictor of the additional dose requirement in single-dose methotrexate protocol in tubal ectopic pregnancy. Study Design: Observational study. Place and Duration of Study: Depart...

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CBX2 Expression in Colorectal Mucosa-adenoma-adenocarcinoma Sequence

By Bangting Wang, Meina Huang, Xin Wang, Yujen Tseng, Feifei Luo, Jie Liu

ABSTRACT Objective: To investigate the expression of chromobox 2 (CBX2) in colorectal adenoma (CRA) and colorectal cancer (CRC), and analyse its correlation with various clinicopathological parameters. Study Design: Observational study. Place and Duration of Study: Pathology Department, Huashan Hosp...

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Optical Coherence Tomography Angiography Findings in Polycystic Ovary Syndrome

By Neslihan Parmak Yener, Gulten Ozgen, Ayse Tufekci, Levent Ozgen, Gultekin Adanas Aydin

ABSTRACT Objective: To evaluate microstructure and vascularity of macula and optic disc in polycystic ovary syndrome (PCOS) by optical coherence tomography (OCT) and OCT angiography (OCTA). Study Design: Descriptive study. Place and Duration of Study: Department of Ophthalmology and Department of Ob...

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Vitamin D Replacement Effect on Platelet Counts

By Murat Bulent Kucukay, Recep Alanli

ABSTRACT Objective: To determine the effect of vitamin D treatment on platelet counts according to age groups in patients with vitamin D deficiency. Study Design: An observational study. Place and Duration of Study: Outpatient Clinics, Department of Internal Medicine, Faculty of Medicine, Lokman He...

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Does Sternal Cable System Prevent Sternal Complications after Revision Sternal Surgery?

By Levent Altınay, Elif Coşkun Sungur, Anil Özen, Anıl Tekin, Sıtkı Akın Turan, Görkem Yiğit, Ufuk Tütün

ABSTRACT Objective: To determine the efficacy of a sternal wire system in secondary sternal dehiscence after repeat closure of the sternum, following surgical revision after open heart surgery. Study Design: Case-control study. Place and Duration of Study: Department of Cardiovascular Surgery, Zongu...

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Does Access Location Influence Outcome of Percutaneous Nephrolithotomy in Staghorn Stones?

By Serkan Yarimoglu, Murat Sahan, Salih Polat, Gurkan Cesur, Omer Koras, Tansu Degirmenci

ABSTRACT Objective: To assess the effect of lower and middle calyceal accesses on the outcomes of percutaneous nephrolithotomy (PCNL) in staghorn stones. Study Design: Observational study. Place and Duration of Study: Department of Urology, University of Health Sciences, Izmir Bozyaka Training and R...

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Peak Growth Hormone Level Variability during Insulin Tolerance Test in Children with Short Stature

By Mohsina Noor Ibrahim, Nadeem Noor, Mehrun Nisa, Taj Muhammad Leghari, Yasir Naqvi Khan, Jamal Raza

ABSTRACT Objective: To determine the variations in peak growth hormone levels during insulin tolerance test (ITT) in diagnosis of growth hormone deficiency (GHD) in children presenting with short stature. Study Design: Descriptive study. Place and Duration of Study: Department of Pediatric Endocrino...

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Risk Factors for the Morbidity and Mortality of Stoma Closure

By Gizem Kilinc, Mehmet Ustun, Korhan Tuncer, Ismail Sert

ABSTRACT Objective: To identify the risk factors for postoperative complications of stoma closures. Study Design: Descriptive study. Place and Duration of Study: Department of General Surgery, Izmir University of Health Sciences, Tepecik Training and Research Hospital, Izmir Turkey from October 200...

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Gastrointestinal Stromal Tumours

By Oguzhan Sunamak, Mehmet Onur Gul, Ismail Ege Subasi, Turgut Donmez, Selvinaz Ozkara

Abstract Objective: To analyse the gastrointestinal stromal tumours (GIST) patients’ inter-demographics, histological type and association with secondary tumours. Study Design: A case series. Place and Duration of the Study: Department of General Surgery, Haydarpasa Numune Training and Researc...

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Reflection as a Learning Tool in Postgraduate Medical Education

By Attia Bari, Izza Imran, Habib Ullah, Ali Arshad, Irfan Naeem, Nadia Sadaqat

ABSTRACT Objective: To explore the reflective capacity as a learning tool in pediatric residents. Study Design: Survey. Place and Duration of Study: The Children’s Hospital Lahore, Pakistan from 20th March to 30th March 2021. Methodology: In this cross sectional online survey, the participants...

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Diagnosis of Levothyroxine Pseudo-malabsorption: The Results of Standardised Testing Protocol

By Mehmet Sözen, Zeynep Canturk, Berrin Cetinarslan, Ilhan Tarkun, Emre Gezer, Alev Selek

ABSTRACT The levothyroxine absorption test for the assessment of pseudo-malabsorption in patients with refractory hypothyroidism has not been standardised. The aim of this observational study was to describe a protocol for levothyroxine (LT-4) absorption test in patients with refractory hypothyroidi...

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A Case of Diffuse Large B-cell Lymphoma with Cardiac Involvement Incidently Diagnosed on Cardiac Imaging

By Asif Husain Osmani, Irfan Maghfoor

ABSTRACT Cardiac lymphomas, either primary or secondary, are mostly of B-cell lineage; among which, diffuse large B-cell lymphoma (DLBCL) is the most common. Secondary involvement of the heart is usually a late manifestation of disseminated lymphoma. Patients may be asymptomatic or may have non-spe...

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Anti-leucine-rich-glioma-inactivated 1 Limbic Encephalitis: An Underrecognised Disease

By Danish Nabi, Mian Ayaz-Ul-Haq, Mehtab Alam, Saqib Ali, Shoaib Ismail, Amjad Iqbal

ABSTRACT Autoimmune limbic encephalitis is a rare autoimmune disease characterised by inflammation of the limbic system of the brain. The disease runs a sub-acute course with cognitive impairment, memory loss and seizures. These patients have been underdiagnosed in Pakistan. Here, we present a case ...

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Detection of Serous Tubal Intraepithelial Carcinoma along with High Grade Serous Carcinoma of Both Ovaries

By Hina Tariq

ABSTRACT High-grade serous carcinoma (HGSC) of ovary is the commonest of all ovarian malignant tumours and is associated with high mortality rate. Serous tubal intraepithelial carcinoma (STIC) is believed to be the precursor lesion. In literature, only 40-50% of HGSC shows concurrent STIC, even aft...

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Scapular Winging Secondary to Iatrogenic Spinal Accessory Nerve Lesions

By Selin Ozen, Sacide Nur Saracgil Cosar, Sevgi Ikbali Afsar, Sehri Ayas

ABSTRACT Motor innervation of trapezius and sternocleidomastoid (SCM) muscles is provided solely by the spinal accessory nerve (SAN). SAN palsy most often occurs as a result of iatrogenic injury to the nerve. A patient, who had undergone neck dissection for thyroid cancer, presented with pain and r...

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Cladophialophora Bantiana as a Cause of Rare Fungal Brain Abscess

By Zafar Ali, Muhammad Usman, Usama Rehman, Fatima Anwar

ABSTRACT Cerebral phaeohyphomycosis refers to central nervous system infection caused by dematiaceous molds, which have many genuses. Cladophialophora bantiana is a member of the phylum ascomycota, which is found in soil samples from all over the world. This organism typically infects immu...

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Familial Amyloidotic Polyneuropathy Type 1: A Hereditary Legacy

By Joel Pinto, Paulo Almeida, Flavio Pereira, Susana Cavadas

ABSTRACT Familial amyloidotic polyneuropathy type 1 (FAP 1) is a systemic autosomal dominant amyloidosis, associated with transthyretin mutation. It is characterised by motor, autonomic and sensory neuropathy with relentless progression that results from amyloid deposition in different tissues. The ...

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Adoption of Digital Pathology in Developing Countries: From Benefits to Challenges

By Talat Zehra, Asma Shabbir

ABSTRACT Digital pathology and the use of artificial intelligence constitute undisputedly the future of modern pathology. The outcomes and benefits of the whole slide imaging are beyond the scope of traditional microscopy, which the pathologists were using for decades. COVID-19 pandemic has further ...

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Challenges Faced by Lady Surgeons during Professional Progress in Pakistan

By Amna Ahmed Noor, Wajiha Shadab, Saira Waqqar

ABSTRACT The purpose of this qualitative study was to investigate the professional challenges faced by lady surgeons in Pakistan. This qualitative exploratory phenomenological study was conducted from April 2019 to June 2019. Four lady surgeons participated in in-depth interviews, based on four ques...

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Sunlight Exposure: A Protective Role in the Development of Myopia

By Syed Ali Hasan Naqvi, Zaka Ur Rehman, Tehmina Nazir, Amna Rizwan, Hassan Raza, Naila Obaid

ABSTRACT The study objective was to assess the correlation of time outdoors in sunlight hours with spherical equivalent refraction (SER) and other variables. This was a cross-sectional study carried out in the Fauji Foundation Hospital, Rawalpindi, between January and April 2019. A total of 110 Indi...

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Use of Remifentanil in Monitored Anaesthesia Care (MAC) in Patients Undergoing Extracorporeal Shock Wave Lithotripsy

By Abdul Saboor Memon, Nasrullah Sheikh, Anwar Ul Huda

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Student-Centred or Teacher-Centred: Promises and Pitfalls of Online Medical Education

By Fahad Azam, Abida Shaheen, Riffat Shafi, Mohammed Amir

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Infective Endocarditis caused by Gemella Sanguinis: A Case with Fever of Unknown Origin and Anemia

By Omer Ekinci, Emrah Ozbek

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Student Research Mentorship Programme: A Novel Solution for Promoting Research in Medical School

By Inaara Akbar, Russell Seth Martins, Syeda Sadia Fatima

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Voiding Difficulty and Recurrent Urinary Tract Infections Secondary to Retained Surgical Sponge after Open Simple Prostatectomy

By Shoaib Rafique, Ammaar Rafique

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Flipped Laboratory Sessions using Video Vignette and Active Learning: A Hybrid Approach for Online Teaching

By Sabah Farhat, Rehana Rehman, Syeda Sadia Fatima

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Special Issue

Special Supplement 2 | Volume 31 | Year 2021
High Neutrophil/Lymphocyte Ratios in Symptomatic Pediatric COVID-19 Patients

By Eren Yildiz, Emrah Cigri, Zubeyde Dincer, Mehmet Ali Narsat, Busra Calisir

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Prealbumin: A New Biomarker for Predicting Prognosis in Patients with Severe COVID-19

By Kubilay Issever, Ahmed Cihad Genc, Deniz Cekic, Ilhan Yildirim, Ahmed Bilal Genc, Selcuk Yaylaci

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Characteristics of Patients Presenting with COVID-19 from Balochistan Province and Lessons Learnt

By Abida Munir Badini, Aurangzeb Badini, Naeem M. Mengal, Kashmira Nanji

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The Strategic Role of Healthcare Professionals in the Battle Against COVID-19: Do We Really Need Help from Community Pharmacists?

By Kashif Ali, Mehwish Wajdi, Osama Al Quteimat

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Obstetrics and COVID-19 Experience: Challenges and Strategies Adapted by a Tertiary Care Hospital in a Developing Country

By Shazia Fakhar, Irram Asghar, Muhammad Ashraf, Ejaz Khan, Sumeyya Azam

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Lung Biopsy in Coronavirus-19 Pneumonia: A Case Report and Review of Literature

By Nadia Mamoon, Imran Nazir Ahmad, Atif Iqbal Rana, Haseeb Haider Zia

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Can COVID-19 Cause Pancreatitis? A Rare Complication of SARS-CoV-2 Infection

By Muhammad Hanif, Abdul Wali Khan, Sadiq Ullah, FNU Sundas, Sheraz jamal Khan

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COVID-19-induced Guillain-Barre Syndrome: A Rare Complication of SARS-CoV-2 Infection

By Muhammad Hanif, Abdul Wali Khan, Muhammad Aslam Khan, FNU Sundas, Sheraz Jamal Khan

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Acute Hepatitis as a Rare Presentation of COVID-19

By Abat Khan, Ihtisham Qayum, Abdul Wali Khan, Muhammad Hanif, Awais Naeem

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Sacral Stress Fracture due to Excess Weight Gain during Pregnancy while Self-Quarantining during the COVID-19 Pandemic

By Rıfat Sahin

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COVID-19-related Abdominal Aortic Thrombosis

By Cengiz Güven

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Acute Ischemic Stroke Associated with COVID-19

By Buse Cagla Ari

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Kawasaki Shock Syndrome and Covid-19

By Sana Ashraf, Farah Shams Abbasi, Mehnaz Atiq

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Post-COVID Neuromyelitis Optica Spectrum Disorder

By Shumaila Rafique, Areeba Wasim, Tipu Sultan, Arsalan Ahmad

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COVID-19 in Hemodialysis Patients

By Sonia Yaqub, Amna Hamid, Zarghoona Naeem

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COVID-19 in Individuals with Drug Abuse - A Case and Thoughts from Emergency Physician

By Sadaf Sheikh

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The use of Pregabalin in Intensive Care Unit in the Treatment of Covid-19-related Pain and Cough

By Sinan Pektas, Canan Gursoy, Semra Gumus Demirbilek

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Peer-assisted Learning (PAL) as an Instructional Tool in Dental Interns in Corona Virus Disease (COVID-19) Scenario

By Thorakkal Shamim

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Delirium in COVID-19: “New Normal” for Care of Older Adults

By Sadaf Sheikh

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Nasopharyngeal Swab Collection Methods for COVID-19: Suggestions from COVID-19 Diagnosticians

By Sadaf Sheikh

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How COVID (Pandemics) Impacted Training of Medical Students, Trainees, and Residents?

By Seema Rawat, Pankaj Kumar Sharma, Amit Narang

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Thrombotic Thrombocytopenia and Central Venous Sinus Thrombosis Post - COVID-19 Vaccination and its Treatment with Heparin Alternatives

By Sadaf Sheikh

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Risk of Invasive Fungal Infections and Osteonecrosis of Jaw in Patients Exposed to Current Therapeutic Drugs for COVID-19

By Muhammad Adil Asim

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