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Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Important Announcement for Authors

"As a large number of case reports are awaiting publication, JCPSP has decided to stop acknowledging Case Reports for a certain period of time until the backlog is cleared. Therefore, case reports are regretted from processing".

Latest Articles
Volume 31 | Issue 11 | November 2021
Journal Prestige Index: Expanding the Horizons of Assessment of Research Impact

By Muhammed Mubarak, Shabana Seemee

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Clinical Outcomes of Physiologically-guided Revascularisation

By Nasir Rahman, Ghufran Adnan, Awais Farhad, Jamshed Ali, Ihsan Ullah

ABSTRACT Objective: To assess the clinical outcomes of revascularisation based on fractional flow reserve (FFR) and/or instantaneous wave-free ratio (iFR). Study Design: Descriptive study. Place and Duration of Study: Department of Medicine, The Aga Khan University Hospital, Karachi from Januar...

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The Implantation of Left Bundle Branch Area Pacing in Patients with and without Bundle Branch Block

By Tian-Ping Chen, Xiao-Jun Shi, Dong-Yu Lu, Heng Zhang

ABSTRACT Objective: To investigate the clinical safety and electrocardiogram (ECG) characteristics in patients with left bundle branch area pacing (LBBAP). Study Design: Retrospective study. Place and Duration of Study: Department of Cardiology, The First Affiliated Hospital of Bengbu Medical Colle...

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Inferior Vena Cava Collapsibility Index and Central Venous Pressure for Fluid Assessment in the Critically Ill Patient

By Afia Arshed Dodhy

ABSTRACT Objective: To determine the correlation of sonographic evaluation of inferior vena cava diameter and its collapsibility index with central venous pressure in both spontaneously breathing and mechanically ventilated patients in surgical ICU.    Study Design: Cross-sectional s...

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Serum Amino Acid Levels and Mortality in Patients Undergoing Percutaneous Endoscopic Gastrostomy

By Ridvan Sivritepe, Sema Ucak Basat, Neslihan Gokmen

ABSTRACT Objective: To evaluate the effect of feeding via percutaneous endoscopic gastrostomy tube (PEG) on serum amino acid levels and mortality. Study Design: Descriptive study. Place and Duration of Study: University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkey, f...

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The Relationship between Decorin and VEGF in Endometriosis

By Habibe Ayvaci, Gultekin Adanas Aydin, Nermin Koc, Nazan Tarhan, Oya Demirci

ABSTRACT Objective: To evaluate immunohistochemical (IHC) staining of decorin and vascular endothelial growth factor (VEGF) of ovarian and endometrial tissues in patients with and without endometriosis.  Study Design: Descriptive study. Place and Duration of Study: Department of Obstetrics and...

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The Relationship between Polycystic Ovary Syndrome and Serum Periostin Level

By Gulsum Gonulalan, Ibrahim Guney, Fatih Sackan, Saadet Acar

ABSTRACT Objective: To determine the changes of circulating periostin levels in polycystic ovary syndrome (PCOS) and its relationship with metabolic disorders. Study Design: Cross-sectional study. Place and Duration of Study: Konya Research and Training Hospital, Turkey between September 2018 and Ap...

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Frequency of Specific Genes in Different Types of Epilepsy

By Neslihan Duzkale, Rıdvan Akın

ABSTRACT Objective: To determine the diagnostic importance of using an exome-based multigene panel in childhood epilepsy. Study Design: Observational study. Place and Duration of Study: Department of Medical Genetics, Diskapi Yildirim Beyazid Training and Research Hospital, from January 2017 to May...

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Serum Hepcidin and Prohepcidin Levels in Nonfebrile and Febrile Neutropenia

By Basak Unver Koluman, Esin Avci, Nil Guler, Gulsum Akgun Cagliyan, Hande Senol

ABSTRACT Objective: To compare the prohepcidin and hepcidin levels in the afebrile neutropenic period and neutropenic fever in patients with hematological malignancy. Study Design: Descriptive study. Place and Duration of Study: Department of Hematology, Pamukkale University Hospital, Denizli, Turke...

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Cytoreductive Surgery versus Systemic Chemotherapy alone in Isolated Peritoneal Carcinomatosis of Colorectal Origin

By Melike Ozcelik, Abdlkerim Oyman, Ibrahim Cil, Ozgul Duzgun, Omer Faruk Ozkan, Murat Ayhan

ABSTRACT Objective: To compare the overall survival and progression-free survival of front-line cytoreductive surgery (CRs) ± hyperthermic intraperitoneal chemotherapy versus intensive systemic chemotherapy alone, in patients with isolated peritoneal carcinomatosis of colorectal origin. Study...

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Impact of Muscle Mass Depletion on Surgical Outcomes in Patients with Primary High-grade Serous Ovarian Cancer Undergoing CRS and HIPEC

By Umit Mercan, Basak Gulpinar, Ogun Ersen, Koray Kosmaz, Abdullah Durhan, Ali Ekrem Unal

ABSTRACT Objective: To investigate the effect of sarcopenia on surgical outcomes in patients with primary high-grade serous ovarian cancer undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS and HIPEC). Study Design: Descriptive study. Place and Duration of Study: Dep...

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Long-term Functional Difference between the First and Second Knees in Simultaneous Bilateral Total Knee Arthroplasty

By Omer Ersen, Ahmet Burak Bilekli, Serhat Uzun, Yusuf Erdem, Dogan Bek, Cemil Yildiz

ABSTRACT Objective: To compare the long-term functional results of the first and second knees in simultaneous bilateral total knee arthroplasty. Study Design: Descriptive study. Place and Duration of Study: Gulhane Education and Research Hospital, Ankara, Turkey from January 2003 to December 2010. ...

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The Effects of Secondary Hyperparathyroidism on Circadian Blood Pressure in Hemodialysis Patients

By Burkay Yakar, Erhan Onalan, Edibe Pirincci, Mehmet Onur Kaya, Mustafa Demir

ABSTRACT Objective: To determine the relationship between secondary hyperparathyroidism (sHPT) and circadian blood pressure (BP) rthym among patients undergoing hemodialysis treatment. Study Design: A descriptive and prospective cohort study. Place and Duration of Study:  Department of Nephrolo...

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Assessing the Learning Process of Laparoscopic Sleeve Gastrectomy with Different Approaches

By Gokhan Selcuk Ozbalcı, Vahit Mutlu, Ismail Alper Tarım

ABSTRACT Objective: To determine the learning curve (LC) of laparoscopic sleeve gastrectomy (LSG) based on an excess weight loss (EWL). Study Design: Observational study. Place and Duration of Study: Ondokuz Mayis University, Faculty of Medicine, Department of General Surgery, from December 201...

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Insulin and Heparin Therapies in Acute Pancreatitis due to Hypertriglyceridemia

By Engin Altinkaya, Ahmet Aktas

ABSTRACT Objective: To compare insulin infusion and heparin infusion, used to treat hypertriglyceridemia-induced acute pancreatitis in terms of efficacy. Study Design: Descriptive study. Place and Duration of Study: Department of Gastroenterology, Division of Internal Disease, Sivas Cumhuriyet Unive...

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Prevalence of Anemia and Associated Risk Factors among Pregnant Women, What is the Role of Antenatal Care in Prevention? A Cross-sectional Study

By Burkay Yakar, Edibe Pirincci, Mehmet Onur Kaya, Erhan Onalan

ABSTRACT Objective: To determine the prevalence of anemia with the associated factors in pregnant women and the effect of family medicine practice and antenatal care services provided by family physicians on the prevention of anemia during pregnancy. Study Design: Community-based cross-sectional stu...

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Changes in the Anterior Lens Epithelium and Basement Membrane in Pseudoexfoliation Syndrome undergoing Surgery for Senile Cataracts: A Transmission Electron Microscopic Study

By Ozlem Dikmetas, Yasemin Kapucu, Aysegul Firat, Mustafa Fevzi Sargon, Sibel Kocabeyoglu

ABSTRACT Objective: To compare the electron microscopic lens findings with and without pseudoexfoliation syndrome (XFS), in patients undergoing surgery for senile cataract. Study Design: A descriptive study. Place and Duration of the Study: Ophthalmology Department, Hacettepe University Hospital bet...

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Adult Retroperitoneal Mature Cystic Teratoma Masquerading as Non-Endocrine Primary Adrenal Tumor

By Fatima Tuz Zahra Shakir, Rizwan Sultan, Riaz Siddiqui, M. Zubair Shah, Ayesha Javed

ABSTRACT Teratomas belong to non-seminomatous germ cell tumors and originate from totipotent germ cells. They are mostly made up of tissues derived from all three layers, i.e., endoderm, mesoderm and ectoderm. They can be mature teratomas, which are benign or immature teratomas, having malignant pot...

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A Case of Foveoschisis Associated with Ornithine Aminotransferase Deficiency and Gyrate Atrophy

By Sehnaz Ozcaliskan, Sevcan Balci, Ozgur Artunay

ABSTRACT Gyrate atrophy is a metabolic disorder characterised by typical progressive circular chorioretinal atrophy, myopia and early developmental cataract. The disease is caused by deficiency of ornithine aminotransferase (OAT) enzyme. Although OAT is expressed in most tissues of the body, but the...

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A Rare Case of Posterior Interosseous Nerve Palsy Post-venepuncture

By Raymond D.K. Yeak, Yee Yee Yap, Nizlan M. Nasir

ABSTRACT Wrist drop post-venepuncture is uncommon. There has been reported cases of direct injury to the radial nerve during venepuncture but to our knowledge, there has never been a case of posterior interosseous nerve (PIN) injury. A 34-year female, right hand dominant homemaker, with a newly diag...

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Use of Eculizumab in Thrombotic Microangiopathy Associated with Hematopoietic Stem Cell Transplantation

By Sinan Demircioglu, Ali Dogan, Cengiz Demir

ABSTRACT Thrombotic microangiopathy (TMA) associated with hematopoietic stem cell transplantation, remains a difficult complication due to its high mortality rate, lack of standardised diagnostic criteria, and limited treatment options. Although the etiology of the disease is not clear, medications,...

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Primitive Neuroectodermal Tumor of the Testis

By Tarık Demir, Altay Aliyev, Mesut Seker, Cevper Ersoz, Ganime Coban, Haci Mehmet Turk

ABSTRACT A 21-year male presenting with left testicular mass and retroperitoneal lymphadenopathy underwent radical orchiectomy; and his pathological examination showed a mixed germ cell tumor composed of primitive neuroectodermal tumor mixed with mature teratoma. Six cycles of IE (ifosfamide, etopos...

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A Case of Lung Abscess Mimicking Lung Cancer

By Nevhiz Gundogdu

ABSTRACT The radiological appearance of lung abscess is nonspecific and can masquerade as a mass lesion during the early phase. The treatment is primarily medical, but surgical treatment is necessary when the size is larger than 6 cm and when patients show any indications of massive hemoptysis, empy...

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MRI-based Diagnosis of Anterior Talofibular Ligament Injury

By Lin An, Yaowen Yan

ABSTRACT The aim of this study was to explore the value of magnetic resonance imaging (MRI) in the diagnosis of anterior talofibular ligament injury. Eighty-two patients, diagnosed with anterior talofibular ligament injury by pathological examination after operation, were included. MRI showed that t...

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Impact of COVID-19 Pandemic on Treatment of Pediatric Oncology Patients: Report from Resource-limited Setting

By Irfana Ishaq Sindhu, Saliha Sarfraz, Najma Shaheen, Anum Khan, Haleema Saeed

ABSTRACT The aim of this study was to determine how the COVID-19 pandemic impacted on the effective management; and the outcome of pediatric oncology patients in Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore. Data was retrospectively reviewed from 15 March to 15 June 2020 aft...

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The Influence of OPRM1 A118G Polymorphism on the Dosage of Morphine in Patients with Advanced Liver Cancer

By Hongzhen Cheng, Xiaoyan Chu, Shenghua Yi

ABSTRACT This study was conducted to investigate the influence of μ-opioid receptor gene (OPRM1) A118G polymorphism on dosage of morphine in advanced liver cancer patients. Seventy patients with advanced liver cancer at Changyi People's Hospital, Shandong Province, China, were included from ...

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Foreign Body Granuloma, Secondary to Retained Toothbrush Head

By Pir Abdul Ahad Aziz Qureshi, Hafeez Ur Rehman Junejo, Muhammad Talha Yaseen Kaimkhani

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A Case of Primary Undifferentiated Pleomorphic Sarcoma of the Lung

By Asuman Kilitci, Fahri Yilmaz, Haciali Kilicgun, Nesrin Uygun

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Clinical Findings in Pheochromocytoma

By Gulali Aktas

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SHANK2-FGFR1: A Novel FGFR1 Rearrangement in a Patient with Intestinal Adenocarcinoma

By Hongguang Sheng, Yugang Jiang, Ling Li

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Philadelphia Chromosome Positive B-lymphoblastic Leukemia in an Infant

By Hadia Khanani, Neelum Mansoor, Naeem Jabbar

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Crossed Cerebellar Diaschisis in a Child with Status Epilepticus

By Talha Durrani, Mian Ayaz Ul Haq, Hira Ishaq, Tanveer Fatima, Aamir Khan

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The Medial and Posterior Compression of the Distal Femoral Vein: An Underused Approach to Detect Venous Thrombosis

By Yale Tung Chen

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Special Issue

Special Supplement 2 | Volume 31 | Year 2021
High Neutrophil/Lymphocyte Ratios in Symptomatic Pediatric COVID-19 Patients

By Eren Yildiz, Emrah Cigri, Zubeyde Dincer, Mehmet Ali Narsat, Busra Calisir

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Vitamin-D Supplementation in COVID-19: Existing Evidence and Gap in Literature

By Muhammad Abbas Abid, Hafsa Majid, Aysha Habib Khan

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Prealbumin: A New Biomarker for Predicting Prognosis in Patients with Severe COVID-19

By Kubilay Issever, Ahmed Cihad Genc, Deniz Cekic, Ilhan Yildirim, Ahmed Bilal Genc, Selcuk Yaylaci

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Can Dentists Prevent Black Fungus in Post-COVID-19 Patients?

By Syed Jaffar Abbas Zaidi, Shahida Maqsood

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Characteristics of Patients Presenting with COVID-19 from Balochistan Province and Lessons Learnt

By Abida Munir Badini, Aurangzeb Badini, Naeem M. Mengal, Kashmira Nanji

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Physical Distancing while Connecting Socially

By Syed Jaffar Abbas Zaidi, Muhammad Taqi

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The Strategic Role of Healthcare Professionals in the Battle Against COVID-19: Do We Really Need Help from Community Pharmacists?

By Kashif Ali, Mehwish Wajdi, Osama Al Quteimat

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Telerehabilitation: Need of the Hour in COVID-19 Pandemic

By Anam Aftab, Shafaq Altaf, Sarah Kafeel

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Obstetrics and COVID-19 Experience: Challenges and Strategies Adapted by a Tertiary Care Hospital in a Developing Country

By Shazia Fakhar, Irram Asghar, Muhammad Ashraf, Ejaz Khan, Sumeyya Azam

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Lung Biopsy in Coronavirus-19 Pneumonia: A Case Report and Review of Literature

By Nadia Mamoon, Imran Nazir Ahmad, Atif Iqbal Rana, Haseeb Haider Zia

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Can COVID-19 Cause Pancreatitis? A Rare Complication of SARS-CoV-2 Infection

By Muhammad Hanif, Abdul Wali Khan, Sadiq Ullah, FNU Sundas, Sheraz jamal Khan

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COVID-19-induced Guillain-Barre Syndrome: A Rare Complication of SARS-CoV-2 Infection

By Muhammad Hanif, Abdul Wali Khan, Muhammad Aslam Khan, FNU Sundas, Sheraz Jamal Khan

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Acute Hepatitis as a Rare Presentation of COVID-19

By Abat Khan, Ihtisham Qayum, Abdul Wali Khan, Muhammad Hanif, Awais Naeem

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Sacral Stress Fracture due to Excess Weight Gain during Pregnancy while Self-Quarantining during the COVID-19 Pandemic

By Rıfat Sahin

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COVID-19-related Abdominal Aortic Thrombosis

By Cengiz Güven

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Acute Ischemic Stroke Associated with COVID-19

By Buse Cagla Ari

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Kawasaki Shock Syndrome and Covid-19

By Sana Ashraf, Farah Shams Abbasi, Mehnaz Atiq

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Post-COVID Neuromyelitis Optica Spectrum Disorder

By Shumaila Rafique, Areeba Wasim, Tipu Sultan, Arsalan Ahmad

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COVID-19 in Hemodialysis Patients

By Sonia Yaqub, Amna Hamid, Zarghoona Naeem

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COVID-19 in Individuals with Drug Abuse - A Case and Thoughts from Emergency Physician

By Sadaf Sheikh

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The use of Pregabalin in Intensive Care Unit in the Treatment of Covid-19-related Pain and Cough

By Sinan Pektas, Canan Gursoy, Semra Gumus Demirbilek

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Peer-assisted Learning (PAL) as an Instructional Tool in Dental Interns in Corona Virus Disease (COVID-19) Scenario

By Thorakkal Shamim

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Delirium in COVID-19: “New Normal” for Care of Older Adults

By Sadaf Sheikh

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Nasopharyngeal Swab Collection Methods for COVID-19: Suggestions from COVID-19 Diagnosticians

By Sadaf Sheikh

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How COVID (Pandemics) Impacted Training of Medical Students, Trainees, and Residents?

By Seema Rawat, Pankaj Kumar Sharma, Amit Narang

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Thrombotic Thrombocytopenia and Central Venous Sinus Thrombosis Post - COVID-19 Vaccination and its Treatment with Heparin Alternatives

By Sadaf Sheikh

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Risk of Invasive Fungal Infections and Osteonecrosis of Jaw in Patients Exposed to Current Therapeutic Drugs for COVID-19

By Muhammad Adil Asim

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Patient with Profound Anemia due to Hemorrhoids during the Pandemic Period

By Serdar Ozdemir

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Challenges in the Management of Clubfoot in COVID-19 Pandemic

By Pankaj Kumar Sharma, Vivek Tiwari

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Prealbumin: A New Biomarker for Predicting Prognosis in Patients with Severe COVID-19

By Serdar Ozdemir, Kamil Kokulu

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Point of Care Ultrasound: Use it to its Full Potential in COVID-19 Pandemic

By Sadaf Sheikh, Saif Alghafri

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