Journal of College of Physicians and Surgeons Pakistan (JCPSP), is the prestigious, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Latest Articles
Volume 29 | Issue 10 | October 2019
Immune Checkpoint Inhibitors: Response Assessment and Immune-related Adverse Events

By Nosheen Fatima, Maseeh uz Zaman

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Pectoral Nerves I, II and Serratus Plane Blocks in Multimodal Analgesia for Mastectomy: A Randomised Clinical Trial

By Hammad Nabeel Najeeb, Syed Raza Mehdi, Athar Mukhtar Siddiqui, Syeda Kiran Batool

Objective: To primarily assess pain score in first 24 hours in PECS (PECtoral Serratus) block group undergoing mastectomy; secondary objective was to observe opioid and antiemetic consumption in the postoperative period. Study Design: Observer-blinded randomised control trial. Place and Duration ...

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Reinforced Laryngeal Mask in Pediatric Laparoscopic Surgery

By Xiao-Li Sun, Jie Li, Zhen-Yuan Wang, Ming-Ying Li, Wei Duan, Nan Wu, Ou Yang

Objective: To determine the frequency of reflux and aspiration in children subjected to reinforced laryngeal mask during laparoscopic surgery in the Trendelenburg position, and evaluate its feasibility. Study Design: A descriptive study. Place and Duration of Study: Department of Anesthesiology, ...

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Association Between Neutrophil-to-Lymphocyte Ratio and Mortality in Neurological Intensive Care Unit Patients

By Muhammed Nur Ogun, Elif Yaksi

Objective: To investigate the effect of neutrophil-lymphocyte ratio (NLR) on survival and mortality in patients who were interned in the Neurology Intensive Care Unit (NICU). Study Design: A cohort study. Place and Duration of Study: Tertiary referral hospital in Bolu, Turkey, between February 20...

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Agreement Between 64-Slice Multidetector CT Angiography and Transthoracic Echocardiography in Detection of Extracardiac Findings of Congenital Heart Disease

By Adeel Asghar Malik, Furqan Ahmad, Sameera Amir, Javaid Asgher, Khalid Farooq

Objective: To determine the degree of agreement between multi-detector computed tomography angiography and transthoracic echocardiography in diagnostic evaluation of congenital heart disease with extracardiac findings. Study Design: Descriptive cross-sectional study. Place and Duration of Study: ...

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May Nesfatin-1 be a Biomarker in Acute Mesenteric Ischemia?

By Cihad Tatar, Fatih Alper Ahlatci, Ufuk Oguz Idiz, Ali Emre Nayci, Said Incir, Orhan Agcaoglu, Cemile Idiz, Emre Balik

Objective: To investigate the diagnostic value of nesfatin-1 in cases of intestinal ischemia and ischemia/reperfusion. Study Design: An experimental study. Place and Duration of Study: The Experimental Animals Laboratory of Bezmialem University, in June 2018. Methodology: Twenty-one healthy male ...

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Safety and Efficiency of Laparoscopic Femoral Hernia Repair with Preserved Uterine Round Ligament

By Mingxiao Guo, Dongfeng Chen, Haifeng Zhang, Chunlei Lu

Objective: To evaluate the efficiency and safety of the transabdominal preperitoneal (TAPP) technique with or without preserved uterine round ligament for the repair of femoral hernias (FHs), on the female patients treated at a single centre. Study Design: Comparative-descriptive study. Place and...

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Hepatic Steatosis in Chronic Hepatitis B as Measured by Controlled Attenuation Parameter: Frequency and Distribution

By Shiying Nan, Yan Liang, Yundong Qu, Feng Liu, Lei Wang, Tao Li

Objective: To determine the frequency of liver steatosis in chronic hepatitis B (CHB) patients measured by controlled attenuation parameter (CAP) and to describe the distribution of fibrosis and inflammation in different steatosis grading. Study Design: Cross-sectional study. Place and Duration o...

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Comparison between Intramedullary Nailing and Minimally Invasive Percutaneous Plate Osteosynthesis in Treatment of Humeral Shaft Fractures

By Hang Yuan, Ran Wang, Jie Zheng, Yonghong Yang

Objective: To compare the efficacy of intramedullary nailing (IMN) and minimally invasive percutaneous plate osteosynthesis (MIPO) in treatment of humeral shaft fractures. Study Design: Descriptive study. Place and Duration of Study: Department of Orthopedics, Zhejiang Hospital, China, during Mar...

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Unilateral and Bilateral Percutaneous Kyphoplasty for Thoracolumbar Osteoporotic Compression Fractures

By Jin Tang, Wei-chun Guo, Jin-feng Hu, Ling Yu

Objective: To compare the efficacies of unilateral and bilateral percutaneous kyphoplasty (PKP) in the treatment of thoracolumbar osteoporotic compression fractures. Study Design: Experimental study. Place and Duration of Study: Department of Orthopedics, Hubei 672 Orthopedics Hospital of Integra...

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C-reactive Protein as a Screening Biomarker in Neonatal Sepsis

By Faisal Khan

Objective: To measure validity of C-reactive protein (CRP) as screening test for neonatal sepsis (NS) and compare its screening validity between early onset neonatal sepsis (EONS) and late onset neonatal sepsis (LONS). Study Design: Cross-sectional study Place and Duration of Study: Neonatal Unit...

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Effectiveness of Deep Breathing Exercises and Incentive Spirometry on Arterial Blood Gases in Second Degree Inhalation Burn Patients

By Summyia Siddique Malik, Naureen Tassadaq

Objective: To find out the effectiveness of the deep breathing exercises and incentive spirometryon arterial blood gases in second degree inhalation burn patients. Study Design: Randomised control trial. Place and Duration of Study: The study was conducted in the Burns Unit of PIMS Hospital, Isla...

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Impact of Curative Effect of Laparoscopic and Open Partial Nephrectomy for Complex Renal Tumours on Renal Function

By Hong-mei Li, Peng Sun, Wen-zeng Yang, Zhen-yu Cui

Objective: To explore the effect and safety of laparoscopic partial nephrectomy (LPN) and open partial nephrectomy (OPN) in the treatment of complex renal tumours and to compare renal function in the perioperative period. Study Design: Comparative study. Place and Duration of Study: Departments o...

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Diagnostic Value of Serum Biomarkers for Intrahepatic Cholangiocarcinoma

By Youdi Li, Yandi Huang, Jiu Chen

Objective: To explore the diagnostic value of carbohydrate antigen 19-9 (CA 19-9) and carcinoembryonic antigen (CEA) for the diagnosis of intrahepatic cholangiocarcinoma (ICC). Study Design: Case control study. Place and Duration of Study: First Affiliated Hospital, College of Medicine, Zhejiang ...

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Two Years Remission of Type 2 Diabetes Mellitus after Bariatric Surgery

By Nauman Wazir, Muhammad Fahad Arshad, John Finney, Katie Kirk, Shivani Dewan

Objective: To determine the influence of bariatric surgery on remission of type 2 diabetes mellitus (T2DM) in obese patients along with improvements in other obesity-associated comorbidities. Study Design: Observational study. Place and Duration of Study: Doncaster and Bassetlaw NHS Trust, UK, fr...

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Serum Des-gamma-carboxy Prothrombin for Diagnosis of Adult Primary Cancer in Liver

By Youdi Li, Jiu Chen

Objective: To explore the diagnostic accuracy of serum des-gamma-carboxy prothrombin (DCP) in adult primary cancer in liver. Study Design: Descriptive study. Place and Duration of Study: Department of Traditional Chinese Medicine, the First Affiliated Hospital, College of Medicine, Zhejing Unive...

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Quality Evaluation of the Non-Variceal Upper Gastrointestinal Bleeding Guidelines/Consensuses via AGREE II Tools

By Yu Wang, Jun Guo, Youyi Rao, Gui Rong Xiao, Xinhua Zhao

Non-variceal upper gastrointestinal bleeding (NUGIB) is a common disease in clinical practice; and many related guidelines/consensuses have been published. The authors assessed the methodological quality of the NUGIB guidelines/ consensuses published in English, in order to uncover which guideline...

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Heparin-induced Thrombocytopenia in Pediatrics Following Cardiopulmonary Bypass

By Shi-Min Yuan

Heparin-induced thrombocytopenia (HIT) is an immune-mediated response to heparin administration. HIT following cardiopulmonary bypass (CPB) procedures has not been clearly delineated in pediatric populations. By comprehensive retrieval of the pertinent literature published since 2000, 19 reports w...

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A Rare Injury in Children: Sternum Fractures

By Ibrahim Ethem Ozsoy, Mehmet Akif Tezcan

Although there are a lot of data on intrathoracic and extrathoracic injuries associated with adult sternal fractures and how to manage them; but there is not much data on diagnosis and treatment protocols, since they are rare in children. If the child patient has a sternal fracture, he/she probabl...

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Emergent Transcatheter Aortic Valve Implantation as a Life-saving Procedure: A Primary Treatment Approach

By Emre Ozdemir, Fatma Kayaalti Esin, Selcen Yakar Tuluce, Mustafa Karaca

Severe aortic stenosis (SAS) is the most common valvular heart disease in elderly patients. Untreated SAS is known to have 50% mortality within 2 years of onset of symptoms. SAS with acute decompensated heart failure is fatal and requires immediate, appropriate treatment. Urgent transcatheter aort...

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Laparoscopic Cholecystectomy in Situs Inversus Totalis

By Falak Sher Malik, Usman Ismat Butt, Wasim Hayat Khan, Syed Muhammad Bilal, Muhammad Umar, Said Umer

Situs inversus is a rare condition. It is characterised by reverse handed positioning of the internal viscera. Laparoscopic cholecystectomy is the standard procedure for cholelithiasis, but it may lead to technical difficulties in case of situs inversus, especially to right-handed surgeons. A 40-y...

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Pure Lumbar Epidural Cavernous Hemangioma with Contralateral Symptoms Complicated by Spondylolisthesis

By Pan Qiao, Tiantong Xu, Wen Zhang, Wenyuan Ding, Rong Tian

Pure spinal epidural cavernous hemangioma with contralateral symptoms is rarely reported. It will be very difficult to diagnose when it is complicated by contralateral symptoms. A 56-year female presented with pure lumbar epidural cavernous hemangioma with contralateral symptoms. Physical examinat...

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Adult Necrotising Enterocolitis in a Breast Cancer Patient after First Cycle of Adjuvant Chemotherapy

By Fatima Tuz Zahra Shakir, Rizwan Sultan, Riaz Siddiqui, M. Zubair Shah, Ayesha Javed

Chemotherapy-induced diarrhea has become a worrisome problem for the patients as well as the treating surgeons and oncologists because patient outcome is significantly affected. Necrotising enterocolitis is a rare disease in adults. It is now termed as neutropenic enterocolitis in adults, because ...

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Curative Effects of Valsartan Alone or Combined with Alpha-lipoic Acid on Inflammatory Cytokines and Renal Function in Early-stage Diabetic Kidney Disease

By Ziyuan Jiang, Zhen Tan, Fanqing Meng, Xiao Li

The aim of this study was to compare curative effects of valsartan alone or combined with alpha-lipoic acid (ALA) on inflammatory cytokine indices including hypersensitive C-reactive protein (hs-CRP), tumor necrosis factor-alpha (TNF-α) and renal function indices including urinary albumin ex...

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Epithelial Cells in Patients with Fixed Orthodontic Appliances

By Rawabi Alsalhi, Lujain Alkhedhairi, Sultana Alsaikhan, Rabia Bilal, Shokria Ghneim

The aim of this study was to assess the morphological changes of oral mucosa epithelial cells in contact with fixed orthodontic appliances using exfoliated cytology. This study was conducted on 100 individuals that were divided into two groups (50 each). Buccal cytological smears were collected fr...

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Aortoenteric Fistula: A Difficult Situation Requiring Multiple Treatment Options

By Zia Ur Rehman, Ziad Sophie

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Effect Analysis of Hyperbaric Oxygen Therapy with Methylprednisolone on Prevention of Spinal Cord Ischemia-Reperfusion Injury

By Yuan Chen, Ziyan Fan, Lingyi Liao, Yunzhu Lin

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Delayed Diagnosis of Esophageal Fistula Associated with Malignancy

By Vitorino Modesto dos Santos, Lister Arruda Modesto dos Santos

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Racemose Hemangioma of Retina with Vein Occlusion

By Rabia Chaudhry, Areej Riaz

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Future of Personalised Medicine: Pharmacoprinting of the Polypill

By Sana Habib, Syed Maaz Tariq, Sara Habib

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Special Issue

Special Supplement 1 | Volume 29 | June 2019
Case Reports – Special Supplement

By Editor JCPSP

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Growth Hormone and ACTH Deficiency in a Diabetic Adult

By Asif Ali Memon, Mehwish Gilani, Naveed Asif, Nida Basharat

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A Case of Dynamic Evolution of Thyrotoxicosis on Follow-up

By Cong Qing Miao, De Chuan Lu, Jing Jing Liu, Hui Xu, Xin Long Meng

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Coexistence of Papillary Thyroid Cancer and Primary Hyperparathyroidism: Report of Five Cases

By Hasan Calis, Nuraydin Ozlem, Serif Melih Karabeyoglu

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Primary Supraclavicular Cystic Lymphangioma in an Adult: A Rare Presentation

By Mansoor Tariq Azim, Syed Mukarram Hussain, Mohammad Awais Mughal

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An Adult Case of Thiamine-Sensitive Megaloblastic Anemia Syndrome Accidentally Diagnosed Myelodysplastic Syndrome

By Ali Kutlucan

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Endothelial Cysts of Adrenal Gland

By Zafar Ali, Hina Tariq, Usama Rehman

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JC Virus Infection: A Clinical Conundrum

By Hajra Farooq, Saifullah Khan Niazi, Misbah Noor, Eijaz Ghani

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Gastric Tuberculosis

By Naresh Kumar Seetlani, Khalid Imran, Qurat ul Ain Hafeez, Asif Ali, Pyar Ali Fazil, Bareeha Shaukat Sultan, Sulhera Khan

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Congenital Erythropoietic Porphyria: A Rare Case of Photosensitivity with Hemolytic Anaemia and Mental Retardation

By Nadia Shirazi, Payal Chauhan, Rashmi Jindal, Sohaib Ahmad

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Ischemic Skin Necrosis in Hepatorenal Syndrome Patient Secondary to Terlipressin

By Raheel Ahmed, Abdul Haseeb

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Adult-Onset Subacute Sclerosing Panencephalitis Presented with Neuropsychiatric Symptoms

By Abdulkerim Gokoglu, Hasan Tahsin Gozdas

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Primary Extra-renal Wilms' Tumor in Urinary Bladder: Rare Presentation of a Common Pediatric Malignancy

By Irfana Ishaq Sindhu, Haleema Saeed, Rabia Wali, Asma Mehreen

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Ocular Cicatricial Pemphigoid: Camouflaged as Persistent Conjunctivitis

By Jamal-uddin Mughal, Asif Jan Muhammad, Uzma Erum

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Traboulsi Syndrome in Pakistan

By Tehmina Awais, Mehmood Ali, Saad Alam Khan

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Shprintzen-Goldberg Syndrome: A Rare Disorder

By Attia Bari, Nadia Sadaqat, Nadia Nawaz, Iqbal Bano

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Primary Pulmonary Hypertension Associated with Asymptomatic Methylmalonic Aciduria in a Child

By Fatma Zohra Chioukh, Kamel Monastiri

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Primary Iliopsoas Abscess in a Neonate

By Muhammad Umar Nisar, Samer Sikander, Zenab Noorain, Mehr-un-Nisa Shahid Baig, Nadeem Akhtar

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A Rare Cause of Intractable Diarrhea of Infancy

By Salman Ali, Aroma Tariq, Maryam Ghuncha

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A Neonate with Upper GI Bleeding

By Suneeta Khemani, Huma Ghulam Qadir, Mumtaz Malik, Faiqa Hassan

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A Child with Weight Loss and Alacrimation: Triple A Syndrome

By Qurat ul Ain, Naveed Asif, Noreen Shahzad, Waqas Hanif Sheikh

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A Child with Ambiguous Genitalia: An Atypical Presentation

By Waqas Hanif Sheikh, Naveed Asif, Muhammad Younas, Nida Basharat, Qurat-ul-Ain , Noreen

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Erotomania in Depressive Psychosis: Mood Incongruent Delusion in a Depressive Young Woman

By Usama Bin Zubair, Sawera Mansoor

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Polyarthritis as the Initial Presentation of Hyper Eosinophilic Syndrome

By Lubna Nazir, Amir Riaz, Hamza Alam

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Bladder Hernia, Bladder Stone and Contralateral Bowel Hernia: An Usual Combination

By Akif Erbin, Halil Lutfi Canat, Burak Ucpinar, Hayati Malcik

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Adrenal Myelolipoma with Adrenocortical Adenoma Presenting with Hypertension Only

By Fan Yang, Chenyu Sun, Shiyu Pang, Juanjuan Cai, Hao Lin, Wanlong Tan

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Neoaorta Reconstruction Using Both Femoral Veins in a Patient with Secondary Aortoenteric Fistula

By Zia-ur Rehman

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Detection and Management of Pregnancy in Rudimentary Horn of Uterus

By Rizwana Parveen

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