5-Year Impact Factor: 0.9
Volume 36, 12 Issues, 2026

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Latest Articles
Volume 36 | Issue 1 | January 2026
From the Chief Editor’s Desk

By Khalid Masud Gondal

    ...


Climate Change and Medical Curricula: A Mental Health Perspective

By Afzal Javed, Albert Persaud, Helena Ferreira Moura


Diagnostic Accuracy of Anti-Desmoglein 1 and 3 Antibodies by Enzyme-Linked Immunosorbent Assay (ELISA) in Pemphigus Vulgaris

By Maryam Bibi, Muhammad Omair Riaz, Muhammad Hussain, Hamid Nawaz Tipu, Mustajab Alam, Muhammad Aftab Hassan

ABSTRACT Objective: To determine the diagnostic accuracy of anti-Desmoglein 1 (Dsg1) and anti-Desmoglein 3 (Dsg3) antibodies detected by the enzyme-linked immunosorbent assay (ELISA) in clinically suspected cases of pemphigus vulgaris (PV). Study Design: A cross-sectional study. Place and Duration o...

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Super-Resolution MRI Radiomics Combined with Clinical Factors Improves Preoperative Detection of Lymph Node Metastasis in Rectal Cancer

By Liang Zhang, Xueting Qu, Henan Lou, Feng Duan, Jizheng Lin, Guohua Wang

ABSTRACT Objective: To evaluate the clinical utility of a super-resolution (SR) MRI radiomics model integrated with clinical baseline parameters for the preoperative prediction of lymph node metastasis (LNM) in rectal cancer. Study Design: A descriptive study. Place and Duration of the Study: D...

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Diagnostic Accuracy of Cerebroplacental Ratio in Predicting Adverse Perinatal Outcomes in Pregnancies with Intrauterine Growth Restriction

By Javeria Asghar, Bushra Iftikhar, Nasreen Hassan Niazi, Samia Nasreen, Khansa Sana Chaudhary, Syeda Amina Asim Kazmi

ABSTRACT Objective: To evaluate the diagnostic accuracy of the cerebroplacental ratio (CPR) in predicting adverse perinatal outcomes in pregnancies complicated by intrauterine growth restriction (IUGR), using postnatal clinical outcomes as the reference standard. Study Design: An analytical study. P...


Jugular Bulb Position Variability on Temporal Bone HRCT

By Mallick Muhammad Zohaib Uddin, Afifa Jamil, Syed Qasim Hashmi, Muhammad Masood Alam, Illiyun Banani, Shaista Afzal Saeed

ABSTRACT Objective: To determine the prevalence of jugular bulb (JB) variations in a Pakistani population, including high-riding jugular bulbs (HRJB) and JB dehiscence. Study Design: A cross-sectional study. Place and Duration of the Study: Department of Radiology, the Aga Khan University Hospital, ...

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Predictive Value of Standardised Remnant Liver Volume Combined with the ALBI-FIB4 Score for Posthepatectomy Liver Failure

By Sirui Yang, Peipei Ye, Shua Cui, Huimin Dong, Li Guo

ABSTRACT  Objective: To evaluate the predictive efficacy of standardised remnant liver volume (SRLV) combined with the albumin-bilirubin- fibrosis-4 (ALBI-FIB4) score for posthepatectomy liver failure (PHLF) in patients with hepatocellular carcinoma (HCC). Study Design: A descriptive and analyt...


Effect of Mesenchymal Stem Cell Infusion in Stage II-IV Diabetic Nephropathy

By Sohail Sabir, Mohsin Shahzad, Umair Ijaz Malik, Humayoon Shafique Satti, Raheel Iftikhar, Nadia Sial

ABSTRACT Objective: To compare the effect of mesenchymal stem cell (MSC) infusion vs. placebo on glomerular filtration rate (GFR) in patients with stage II-IV diabetic nephropathy. Study Design: A randomised controlled trial. Place and Duration of the Study: Department of Nephrology, Pak Emirates Mi...


A New Method for the Diagnosis of Early Carpal Tunnel Syndrome by Means of Pressurised Electromyography

By Lishuai Miao, Xiaokuan Fu, Peng Li, Tongling Wu, Yuanhui Zhou, Yue Liu

ABSTRACT Objective: To test the diagnosis of early carpal tunnel syndrome (CTS) by assessing dorsal extension, distal sensation, and motor latency. Study Design: An observational study. Place and Duration of the Study: Department of Orthopaedic Surgery, Longgang District People’s Hospital of ...


Nomogram Model Development and Validation for Predicting 90-Day Functional Outcomes in Acute Ischaemic Stroke Patients Post-Endovascular Therapy

By Guizhi Zhang, Bo Jiang, Xiang Li, Wenbing Zeng

ABSTRACT Objective: To develop and validate a nomogram model based on LASSO-logistic regression to predict the 90-day functional prognosis of acute ischaemic stroke (AIS) patients after endovascular therapy (EVT). Study Design: A descriptive study. Place and Duration of the Study: Department of Radi...

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Use of Subdermal Sterile Water Injection toRelievePain in Labour and its Effect in Mode of Delivery

By Samana Haider, Tehmina Aziz Qureshi, Saba Bashir, Sidra Aslam, Zarmina Mushtaq, Kausar Masoom

ABSTRACT Objective: To assess the use of subdermal sterile water injections (SWIs) as a cost-effective and reliable analgesia option for labouring women in setups with high patient flow, limited staff availability, and favourable delivery outcomes. Study Design: Randomised clinical trial. Place and ...

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Molecular and Epidemiological Insights into Oral Squamous Cell Carcinoma: Biomarker Profiling for Prognostic and Therapeutic Advancements

By Sana Mirza, Ikram Din Ujjan, Bin Afshan Syed, Uzma Tariq, Uzma Zareef, Zia Ur Rahman Khan

ABSTRACT Objective: To evaluate the expression of Human Epidermal Growth Factor Receptor (HER) family members (HER1, HER2, HER3, and HER4), along with Ki-67 and E-cadherin in oral squamous cell carcinoma (OSCC), and to determine their prognostic and therapeutic relevance in relation to clinicopathol...


Comparison of Silicone Oil Retention Sutures versus Inferior Peripheral Iridectomy for Preventing Silicone Oil Migration into the Anterior Chamber in Vitrectomised Unicameral Aphakic Eyes

By Imran Manzoor, Asad Aslam Khan, Sidrah Latif, Muhammad Ahmed

ABSTRACT Objective: To evaluate the effectiveness of silicone oil retention sutures versus inferior peripheral iridectomy (PI) in avoiding silicone oil migration in vitrectomised unicameral aphakic eyes. Study Design: A quasi-experimental study. Place and Duration of the Study: College of Ophthalmol...


Effectiveness of Kinesio Taping after Open Appendectomy in Children

By Ibrahim Akkoyun, Bayram Sonmez Unuvar, Hilal Kurt Sezer, Merve Askin Ceran, Muzaffer Erdogan, Sabit Dere

ABSTRACT Objective: To evaluate the effectiveness of kinesio tape (KT) in reducing pain and fear, and in facilitating earlier gas passage in children after open appendicectomy. Study Design: A single-blind randomised controlled trial. Place and Duration of the Study: Department of Paediatric Surgery...

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IGHG1, HLA-DOB, and GABBR1: Genetic Insights into Rheumatoid Arthritis Using Mendelian Randomisation and Single-Cell RNA Sequencing

By Miao Liu, Wen-Jing Lang, Ling Li

ABSTRACT Objective: To identify key genes associated with rheumatoid arthritis (RA) and explore their roles in disease pathogenesis using genomic and single-cell transcriptomic data, with the aim of proposing novel therapeutic targets. Study Design: Bioinformatics-based observational study. Place an...


A Meta-Analysis: PTEN Expression in Relation to Prognosis and Clinical Characteristics of Patients with Colorectal Cancer

By Xiaoli Zhang, Huiguang Chen, Qingming Wu

ABSTRACT The incidence and mortality of colorectal cancer (CRC) are steadily rising. Phosphatase–Tensin Homolog Deleted on Chromosome 10 (PTEN) expression is often dysregulated during tumourigenesis; however, its prognostic value in CRC remains debated. This study evaluated the correlation bet...


Predictors of Residual Tumour in Non-Muscle-Invasive Bladder Cancer Following Repeat Transurethral Resection: A Meta-Analysis

By Jiashuo Li, Yidi He, Shuai Wu

ABSTRACT To systematically evaluate the risk factors associated with positive pathology results following second transurethral resection (re-TUR) in patients with non-muscle invasive bladder cancer (NMIBC), a thorough database search, including PubMed, Embase, Cochrane Library, and CNKI, was perform...


Virtual Microscopy vs. Optical Microscopy: Comparison of Two Teaching Methodologies for Achieving Specific Learning Outcomes in Medical Students

By Sadaf Shafique

ABSTRACT Objective: To compare virtual microscopy (VM) and optical microscopy (OM) as teaching methodologies for pathology in medical education. Study Design: A randomised controlled trial. Place and Duration of the Study: Department of Pathology, Quaid-e-Azam Medical College, Bahawalpur, Pakistan,...


Short-Term Clinical Outcomes and Safety of Microendoscope Discectomy and Unilateral Biportal Endoscopic Discectomy for Lumbar Disc Herniation

By Lilin Liu, Han Li

ABSTRACT Objective: To compare the short-term clinical efficacy and safety of unilateral biportal endoscopic discectomy (UBED) and microendoscope discectomy (MED) in the treatment of lumbar disc herniation (LDH). Study Design: A descriptive study. Place and Duration of the Study: Department of Ortho...


Construction and Validation of a Risk Prediction Model for Immune-Related Adverse Events in Lung Cancer Patients Receiving Immunosuppressants

By Yitao Chen, Xiaoyu Xiang, Lichun Wang, Runmei Wang

ABSTRACT Objective: To examine the factors influencing immune-related adverse events (irAEs) in lung cancer (LC) patients undergoing treatment with immune checkpoint inhibitors (ICIs) and to develop and validate a prediction model. Study Design: An observational study. Place and Duration of the St...

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A Novel Acetabular Biplanar Calibration Method for Establishing Hip Arthroscopic Portals

By Qilong Jiang, Yu Deng

ABSTRACT Objective: To introduce a novel acetabular biplanar calibration (ABC) method to improve the accuracy of hip arthroscopic portal establishment. Study Design: An observational study. Place and Duration of the Study: Department of Orthopaedic Surgery, Chongqing Orthopaedic Hospital of Traditio...


COVID-19 Epidemic: The Turning Point in Ending Sudden Cardiac Death Among Chinese Doctors

By Wei Xiong, Yongmin Shi, Xiyun Rao, Qingwen Yu, Mingwei Wang, Jiake Tang

ABSTRACT Sudden cardiac death (SCD) is a public health problem that affects people worldwide regardless of age and social groups. SCD is an unexpected, sudden death caused by cardiac reasons, which often occurs within one hour of the onset of symptoms. With the rapid development of the economy, popu...


Enhancing Comprehension of Intraoral Radiographic Techniques through Innovative Approaches

By Suresh Kandagal Veerabhadrappa, Jayanth Kumar Vadivel, Seema Yadav Roodmal

ABSTRACT Intraoral radiographs are essential for diagnosis and treatment planning in clinical dentistry. Therefore, mastering these radiographic techniques is a crucial aspect of dental students' clinical training. However, achieving proficiency in these techniques is challenging, as it demands...


Occurrence of Parafunctional Habits in Adults with and without Temporomandibular Disorder: A Cross-Sectional Descriptive Study

By Ateeqa Younis, Nadia Zaib, Maira Tafzeel, Muqaddas Zafar, Hajra Habiba, Sameen Aamir

ABSTRACT The study aimed to determine the occurrence of parafunctional habits in adults with and without temporomandibular disorder (TMD). It was a cross-sectional descriptive study conducted at Fauji Foundation Hospital and Fatima Tuz Zahra Medical Centre, Rawalpindi, Pakistan, from March 2023 to J...


Nucleated Red Blood Cells and Serum Lactate for the Diagnosis of Neonatal Sepsis

By Ayesha Wahid Mian, Helen Mary Robert, Noman Anjum Rana, Ammara Hafeez, Zunairah Mughal

ABSTRACT This study aimed to assess the diagnostic accuracy of nucleated red blood cells (NRBCs) and lactate levels in the severity of neonatal sepsis. A cross-sectional analytical study was conducted at the Department of Haematology, Combined Military Hospital, Lahore, Pakistan. A total of 160 neon...


Explainable Artificial Intelligence: A Crucial Frontier for Pakistan’s Medical and Dental Research

By Javed Ashraf, Syeda Kashaf Abbas, Ulfat Bashir Raja


Nattokinase-Related Aggravation of Histamine Intolerance in Diamine Oxidase Deficiency: A Rare Clinical Observation

By Ilkay Keskinel


Acute Pancreatitis Secondary to H1N1 Influenza in a Child: Clinical Insights and Pathogenesis

By Yanhua Shi, Peisen Ruan, Hehe Chen


Atypical Guillain-Barre Syndrome with Positive Pyramidal Tract Signs and Anti-GM2 IgM Antibody

By Jingyuan Lin


Complete Relief of Massive Cervical Intervertebral Disc Herniation in a Young Patient with a New Regime of Conservative Treatment

By Yao Huang, Chao Zhang


Epstein–Barr Virus as a Trigger for Haemophagocytic Lymphohistiocytosis

By Bilal Ahmed Malik, Sarmad Ali, Arshad Khushdil