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Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Important Announcement for Authors

"As a large number of case reports are awaiting publication, JCPSP has decided to stop acknowledging Case Reports for a certain period of time until the backlog is cleared. Therefore, case reports are regretted from processing".

Latest Articles
Volume 31 | Issue 12 | December 2021
Impact of COVID-19 Pandemic on Disability Care and Persons with Disability in Pakistan

By Farooq Azam Rathore, Ahmad Zaheer Qureshi

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Standard Modifiable Cardiovascular Risk Factors and Prognosis of Acute Coronary Syndrome in Younger Patients

By Xu Chen, Han-xiong Liu, Xiu-qiong Yu, Si-qi Yang, Ling-yao Qi, Lin Cai

ABSTRACT Objective: To investigate standard modifiable cardiovascular risk factors (SMuRFs) and prognosis of patients with acute coronary syndrome (ACS) aged 50 years or younger. Study Design: An observational study. Place and Duration of Study: Eleven general hospitals in Chengdu, Sichuan Province,...

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Diffusion-weighted MRI at 3T in Endometrial Cancer: Correlation of Apparent Diffusion Coefficient with Histopathological Prognostic Parameters

By Mesut Ozturk, Cihan Kalkan, Murat Danaci, Mehmet Kefeli

ABSTRACT Objective: To evaluate the value of apparent diffusion coefficient (ADC) for the differentiation of histological subtypes in endometrial cancer, and to assess if ADC values correlate with histopathological parameters. Study Design: Descriptive study. Place and Duration of Study: Department...

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Predictive Factors of Success in Sleeve Gastrectomy: One-Year Follow-up and the Significance of HALP Score

By Ferhat Cay, Ali Duran

ABSTRACT Objective: To investigate whether HALP score [hemoglobin, albumin, lymphocyte (LY), platelet] can predict weight loss in patients undergoing sleeve gastrectomy. Study Design: A cohort study. Place and Duration of Study: Department of General Surgery, Balıkesir University, Turkey from July ...

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Relationship between Serum Elabela Level and Hypertensıve Nephropathy

By Yusuf Dogan, Erhan Onalan, Cundullah Cavli, Ebru Etem Onalan, Burkay Yakar, Emir Donder

ABSTRACT Objective: To determine the difference in serum Elabela level in hypertensive patients with and without nephropathy compared to the healthy control group. Study Desing:  Cross-sectional descriptive study. Place and Duration of Study: Fırat University Medical School, Elazig, Turkey bet...

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Therapeutic Efficacy of Erythropoietin Alpha and Erythropoietin Beta in Anemia of Chronic Kidney Disease

By Sommiya Dashti, Murtaza Dhrolia, Ruqaya Qureshi, Kiran Nasir, Aasim Ahmad

ABSTRACT: Objective: To compare the effectiveness of erythropoietin alpha and erythropoietin beta in anemia management in the hemodialysis population. Study Design: Quasi-experimental study. Place and Duration of Study: Department of Nephrology, The Kidney Center Postgraduate Training Institute (TKC...

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The Role of Ca 19-9, Ca 72-4, Cea and Cholesterol Levels in Predicting Malignancy in Gallbladder Polyps

By Nazmi Ozer, Alper Sozutek, Abdullah Sahin, Ahmet Seker, Ismail Caner Genc, Ahmet Yugruk

ABSTRACT Objective: To determine the association of malignancy potential of gallbladder polyps with tumor markers and cholesterol levels, and at which value the presence of malignancy should be suspected. Study Design: Observational study. Place and Duration of Study: University of Health Sciences, ...

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Does Prognostic Nutritional Index Predict Survival in Operated Papilla Vateri Tumors? A Single-centre Experience

By Murat Bardakci, Emre Hafizoglu, Fahriye Tugba Kos, Dogan Uncu

ABSTRACT Objective: To determine the PNI’s prognostic effect of prognostic nutritional index (PNI)  on operated papilla vateri tumor (PVT) survival. Study Design: Descriptive study. Place and Duration of Study: Department of Medical Oncology, Ankara City Hospital, Ankara, Turkey, from Apr...

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Survival and Prognostic Factors in Limited-stage Small-cell Lung Cancer

By Muhammed Mustafa Atci, Abdullah Sakin, Emre Uysal, Ferdi Aksaray, Oguzhan Selvi, Orcun Can

ABSTRACT Objective: To evaluate the factors affecting overall survival (OS) and progression-free survival (PFS) in patients with limited stage-small cell lung cancer (LS-SCLC). Study Design: Descriptive study. Place and Duration of Study: Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, Turkey fro...

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Distant Metastasis Patterns of Lung Cancer on Positron Emission Tomography/Computed Tomography Association with Age and Histological Subtype

By Sibel Goksel, Neslihan Ozcelik

ABSTRACT Objective: To investigate whether age or other factors are determinants of distant metastasis in patients with lung cancer. Study Design: Observational study. Place and Duration of Study: Department of Nuclear Medicine, Recep Tayyip Erdogan University, Rize, Turkey between December, 2018 an...

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Effects of S-adenosyl-L-Methionine Combined with Ursodesoxycholic Acid on Serum Endotoxin, MMP-9 and IL-18 in Neonates with Cholestasis

By Lingmei Zeng, Mao Li, Yuting Cen, Zuanyu Wang

ABSTRACT Objective: To compare the effect of ursodesoxycholic acid (UDCA) with S-adenosyl-L-methionine (SAMe) plus UDCA in handling of cholestasis in neonates, and their influences on serum endotoxin, matrix metalloproteinase-9 (MMP-9) and interleukin 18 (IL-18). Study Design: Randomised controlled ...

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Efficacy of Tranexamic Acid on Blood Loss in Thoracolumbar Spinal Fusion Surgery

By Keskin Emrah, Aydin Hasan Ali, Ozgen Utku, Kalayci Murat, Simsek Kenan, Baklaci Deniz

ABSTRACT Objective: To investigate the effectiveness of topical tranexamic acid (TXA) use on bleeding and drain withdrawal time in adult patients undergoing thoracolumbar fusion surgery. Study Design: Cross-sectional comparative study. Place and Duration of Study: Zonguldak Bülent Ecevit Univer...

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Effect of Obesity on Percutaneous Thrombectomy Outcomes in the Treatment of Lower Limb Deep Vein Thrombosis

By Emrah Sevgili, Corc Baytaroglu

ABSTRACT Objective: To evaluate the effect of obesity on percutaneous thrombectomy (PT) results for the management of lower limb deep vein thrombosis (DVT). Study Design: Retrospective cohort study. Place and Duration of Study: Department of Cardiology, Avcilar Hospital, Istanbul, Turkey, between Au...

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The Efficacy of Bronchoscopy versus Computerised Tomography in Initial Identification of Patients with Hemoptysis

By Dingxiu He, Dong Huang, Kaisen Huang, Zongan Liang

ABSTRACT The effects of bronchoscopy and chest CT on early evaluation of patients with hemoptysis are still controversial. PubMed, EMBASE, and the Cochrane Library databases were systematically searched. Odds ratio (OR) was applied to assess the utility of bronchoscopy for hemoptysis etiology and si...

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Effectiveness of Simulation-based Clinical Skills Training for Medical Students in Respiratory Medicine:
A Pilot Study

By Russell Seth Martins, Saniya Raghib Sabzwari, Meesha Iqbal

ABSTRACT Objective: To assess the effectiveness of high-fidelity simulation-based medical education (HF-SBME) in teaching and learning respiratory clinical examination in medical students. Study Design: Quasi-experimental pilot study. Place and Duration of Study: The Aga Khan University, Karachi, f...

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Clinical Analysis of Pancreaticoduodenectomies for Benign Pathologies

By Arif Atay, Feyyaz Gungor, Nihan Acar, Yunus Sur, Fatma Husniye Dilek, Osman Nuri Dilek

ABSTRACT Objective: To evaluate the clinical, laboratory and imaging data of patients who underwent pancreatoduodenectomy (PD) for proven benign pathologies. Study Design: Descriptive study. Place and Duration of Study: Department of General Surgery, İzmir Katip Celebi University, School of Medicin...

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A Comparison of Lower Limb Peripherally Inserted Central Catheter and Deep Venous Catheterisation

By Feng-Xian Li, Yu-Fen Hao, Mei-Jing Tian, Yan-Ping Li, Hong-Yang Zhang

ABSTRACT Objective: To compare the clinical application effects of peripherally inserted central catheter (PICC) and deep venous catheters placed through the lower limbs in adults with malignancy obviating the use of upper limb PICC. Study Design: Descriptive study. Place and Duration of Study: Dep...

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New-onset Diabetes after Renal Transplant and Associated Factors

By Azhar Ali Khan, Waqar Ahmed, Ahmed Ayyaz

ABSTRACT Objective: To assess the frequency and time of onset of new-onset diabetes after transplant (NODAT) and its associated factors. Study Design: Observational study. Place and Duration of Study: Department of Nephrology, Bahria International Hospital, Lahore, Pakistan, from April 2016 to April...

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Gastrointestinal Stromal Tumours of the Small Intestine

By Hakan Uzunoglu, Yasin Tosun, Ozan Akinci, Baver Baris

ABSTRACT Objectives: To describe the spectrum of small intestine gastrointestinal stromal tumour (GIST) cases; and to analyse prognostic factors. Study Design: Descriptive study. Place and Duration of Study: Kartal Dr. Lütfi Kirdar City Hospital, Istanbul, Turkey, from 2010 to 2020. Methodolog...

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Spinal Muscular Atrophy with Respiratory Distress
Type 1: A Novel Variant of IGHMBP2 Gene

By Muhammad Saeed, Walid Fawzy, Saeed Al-Tala, Tayseer Adel Magid, Hala Ahmed

ABSTRACT Spinal muscular atrophy (SMA) with respiratory distress type 1 (SMARD1) is an exceptionally rare type of SMA. It results from disintegration of alpha motor neurons of the spinal cord. Clinically, children affected with this disorder present between the age of six weeks to six months with re...

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A Young Man with a Rare Case of Adrenal Incidentaloma

By Usama Bin Khalid, Qurat Ul Ain, Zujaja Hina Haroon, Muhammad Aamir, Shakeel Ahmad, Shahrukh Shah

ABSTRACT Adrenal incidentalomas (AIs) are adrenal masses discovered as incidental finding, often on imaging studies, unrelated to adrenal disorders. Sometimes, they are discovered as part of work-up for adrenal pathology. AIs are mostly nonfunctional (hormonally silent), but can also be functional (...

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Right Ventricular Blood Cyst in an Adult Autosomal Dominant Polycystic Kidney Disease Patient:
An Unusual Association

By Ersin Cagri Simsek, Dilek Oncel, Erdem Ozel

ABSTRACT Blood cysts of the heart are unusual primary cardiac tumor-like masses, which are usually located on the cardiac valves. These are very rare in adults, especially in a non-valvular location. Autosomal-dominant polycystic kidney disease (ADPKD) typically presents with multiple bilateral rena...

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Pseudoactinomycotic Radiate Granules (PAMRAGs) in the Extensor Tendon of Hand

By Rifat Sahin

ABSTRACT Pseudoactinomycotic radiate granules (PAMRAGs) are most frequently observed in female genitalia. Morphologically, these closely resemble the actual actinomycotic granules. Actinomyces are infectious organisms that require treatment; whereas, PAMRAGs do not require a specific treatment since...

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Prosthetic Rehabilitation of Nasal Septal Defect with Magnet Retained Nasal Septal Prosthesis

By Hina Zafar Raja, Maryam Mumtaz, Muhammad Nasir Saleem

ABSTRACT Nasal septal defects may present with no clinical symptoms to dryness, nasal obstruction, pain, mucosal injury, crusting, epistaxis, rhinorrhea, nasal twang in speech, hyposmia, and breathing difficulties. Prosthetic rehabilitation of these defects may lead to improvement in these condition...

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Thoracic Mass Lesions on Imaging: Beware of Tuberculosis Cases

By Fatih Meteroglu, Atalay Sahin

ABSTRACT Tuberculosis (TB) and thoracic malignancy mimic each other clinically, and pose diagnostic challenges. Both diseases are characterised by similar symptoms. We aimed to emphasise that some forms of TB are associated with misleading clinical and radiological manifestations. We present a retro...

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Role of Citicoline in Treatment of Moderate to Severe Birth Asphyxia: A Pilot Project

By Arshad Khushdil, Zeeshan Ahmed, Azra Ehsan

ABSTRACT An observational cohort study was performed at Neonatal Intensive Care Units of two military hospitals to see the effects of citicoline in neonates diagnosed to have moderate to severe hypoxic ischemic encephalopathy. Twenty newborns fulfilling the inclusion criteria were selected for the s...

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Surgical Management of Subclavian and Proximal Axillary Artery Injuries

By Zia Ur Rehman, Suleman Yousaf, Tehmeed Ahmad

ABSTRACT Subclavian and proximal axillary arterial injuries are rare and difficult to manage. Eight patients were managed from January 2008 to December 2018 at The Aga Khan University Hospital, Karachi, Pakistan with mean age of 36.13 ± 14.48 years. All patients had penetrating injuries, from...

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Durable Left Ventricular Assist Device with Mechanical Mitral and Aortic Valves

By Muhammad Adil Soofi, Faisal Al Ghamdi

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Hereditary Spastic
Paraplegia: Role of MRI

By Abdur Rahim Palwa, Mobeen Shafique, Khurram Haqnawaz

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Intriguing Localisation of “Pacinian Neuroma’’
Diagnosed at Intraoperative Consultation during Whipple Procedure

By Selma Sengiz Erhan, Gamze Kulduk, Mehmet Ozer

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Comment to: Diagnostic Value of Serum Gastrin and Epidermal Growth Factor to the Gastric Ulcer Complicated with Upper Gastrointestinal Hemorrhage

By Firdaus Hayati, Muhammad Aklil Abdul Rahim, Syed Sharizman Syed Abdul Rahim

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Breast Cancer with Metastases to Coronary Arteries

By Asif Husain Osmani, Kausar Suleman

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Laparoscopic Excision of a Pyloric Duplication Cyst in a Child

By Esra Ozcakir, Mete Kaya

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Importance of Multifidus Muscle Activity as a Treatment Outcome Measure in Chronic Low Back Pain

By Aftab Ahmed Mirza Baig, Basit Ansari

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Special Issue

Special Supplement 2 | Volume 31 | Year 2021
High Neutrophil/Lymphocyte Ratios in Symptomatic Pediatric COVID-19 Patients

By Eren Yildiz, Emrah Cigri, Zubeyde Dincer, Mehmet Ali Narsat, Busra Calisir

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Vitamin-D Supplementation in COVID-19: Existing Evidence and Gap in Literature

By Muhammad Abbas Abid, Hafsa Majid, Aysha Habib Khan

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Prealbumin: A New Biomarker for Predicting Prognosis in Patients with Severe COVID-19

By Kubilay Issever, Ahmed Cihad Genc, Deniz Cekic, Ilhan Yildirim, Ahmed Bilal Genc, Selcuk Yaylaci

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Can Dentists Prevent Black Fungus in Post-COVID-19 Patients?

By Syed Jaffar Abbas Zaidi, Shahida Maqsood

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Characteristics of Patients Presenting with COVID-19 from Balochistan Province and Lessons Learnt

By Abida Munir Badini, Aurangzeb Badini, Naeem M. Mengal, Kashmira Nanji

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Physical Distancing while Connecting Socially

By Syed Jaffar Abbas Zaidi, Muhammad Taqi

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The Strategic Role of Healthcare Professionals in the Battle Against COVID-19: Do We Really Need Help from Community Pharmacists?

By Kashif Ali, Mehwish Wajdi, Osama Al Quteimat

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Telerehabilitation: Need of the Hour in COVID-19 Pandemic

By Anam Aftab, Shafaq Altaf, Sarah Kafeel

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Obstetrics and COVID-19 Experience: Challenges and Strategies Adapted by a Tertiary Care Hospital in a Developing Country

By Shazia Fakhar, Irram Asghar, Muhammad Ashraf, Ejaz Khan, Sumeyya Azam

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Lung Biopsy in Coronavirus-19 Pneumonia: A Case Report and Review of Literature

By Nadia Mamoon, Imran Nazir Ahmad, Atif Iqbal Rana, Haseeb Haider Zia

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Can COVID-19 Cause Pancreatitis? A Rare Complication of SARS-CoV-2 Infection

By Muhammad Hanif, Abdul Wali Khan, Sadiq Ullah, FNU Sundas, Sheraz jamal Khan

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COVID-19-induced Guillain-Barre Syndrome: A Rare Complication of SARS-CoV-2 Infection

By Muhammad Hanif, Abdul Wali Khan, Muhammad Aslam Khan, FNU Sundas, Sheraz Jamal Khan

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Acute Hepatitis as a Rare Presentation of COVID-19

By Abat Khan, Ihtisham Qayum, Abdul Wali Khan, Muhammad Hanif, Awais Naeem

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Sacral Stress Fracture due to Excess Weight Gain during Pregnancy while Self-Quarantining during the COVID-19 Pandemic

By Rıfat Sahin

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COVID-19-related Abdominal Aortic Thrombosis

By Cengiz Güven

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Acute Ischemic Stroke Associated with COVID-19

By Buse Cagla Ari

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Kawasaki Shock Syndrome and Covid-19

By Sana Ashraf, Farah Shams Abbasi, Mehnaz Atiq

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Post-COVID Neuromyelitis Optica Spectrum Disorder

By Shumaila Rafique, Areeba Wasim, Tipu Sultan, Arsalan Ahmad

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COVID-19 in Hemodialysis Patients

By Sonia Yaqub, Amna Hamid, Zarghoona Naeem

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COVID-19 in Individuals with Drug Abuse - A Case and Thoughts from Emergency Physician

By Sadaf Sheikh

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The use of Pregabalin in Intensive Care Unit in the Treatment of Covid-19-related Pain and Cough

By Sinan Pektas, Canan Gursoy, Semra Gumus Demirbilek

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Peer-assisted Learning (PAL) as an Instructional Tool in Dental Interns in Corona Virus Disease (COVID-19) Scenario

By Thorakkal Shamim

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Delirium in COVID-19: “New Normal” for Care of Older Adults

By Sadaf Sheikh

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Nasopharyngeal Swab Collection Methods for COVID-19: Suggestions from COVID-19 Diagnosticians

By Sadaf Sheikh

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How COVID (Pandemics) Impacted Training of Medical Students, Trainees, and Residents?

By Seema Rawat, Pankaj Kumar Sharma, Amit Narang

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Thrombotic Thrombocytopenia and Central Venous Sinus Thrombosis Post - COVID-19 Vaccination and its Treatment with Heparin Alternatives

By Sadaf Sheikh

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Risk of Invasive Fungal Infections and Osteonecrosis of Jaw in Patients Exposed to Current Therapeutic Drugs for COVID-19

By Muhammad Adil Asim

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Patient with Profound Anemia due to Hemorrhoids during the Pandemic Period

By Serdar Ozdemir

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Challenges in the Management of Clubfoot in COVID-19 Pandemic

By Pankaj Kumar Sharma, Vivek Tiwari

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Re-Prealbumin: A New Biomarker for Predicting Prognosis in Patients with Severe COVID-19

By Serdar Ozdemir, Kamil Kokulu

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Point of Care Ultrasound: Use it to its Full Potential in COVID-19 Pandemic

By Sadaf Sheikh, Saif Alghafri

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