Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.

The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.

Latest Articles

Volume 36 | Issue 4 | April 2026

Genetic and Molecular Profiling of Breast Cancer in Pakistan: A Missed Opportunity?

By Amna Batool, Urooj Bhatti
Page # 431-432

Effects of the Erector Spinae Plane Block on Stress Response and Analgesic Consumption in Patients Undergoing Lumbar Disc Surgery: A Prospective, Randomised, Single-Blind Study

By Ramazan Aslanparcasi, Erdogan Duran, Veli Fahri Pehlivan, Basak Pehlivan, Abdullah Sengul
Page # 433-438

ABSTRACT Objective: To assess the effect of bilateral erector spinae plane block (ESPB) on postoperative analgesic requirements, patient and surgeon satisfaction, postoperative stress response, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) values in patients undergoing...

Association Between SYNTAX Score and Neopterin Levels in Patients with Chronic Coronary Artery Disease

By Zeynep Yapan Emren, Sadik Volkan Emren, Oktay Senoz, Levent Elmas
Page # 439-443

ABSTRACT Objective: To explore the relationship between the Synergy between Percutaneous Coronary Intervention with TAXUS and Cardiac Surgery (SYNTAX) score and neopterin levels in patients with coronary artery disease (CAD). Study Design: An observational study. Place and Duration of the Study: Ca...

Analysis of Risk Factors for Gastrointestinal Polyps in Patients with Type 2 Diabetes Mellitus

By Licai Rong, Congjia Liang, Yihong Zhang
Page # 444-449

ABSTRACT Objective: To investigate the risk factors associated with gastrointestinal polyps in patients with type 2 diabetes mellitus (T2DM). Study Design: A case-control study. Place and Duration of the Study: Department of Endocrinology, Heilongjiang Provincial Hospital, Harbin, China, from Januar...

Response Evaluation and Surveillance of Head and Neck Tumours Using the NI-RADS Algorithm

By Sara Shahid, Rashed Nazir, Ahmed Moqeet, Amna Mehboob, Maryam Rauf, Khurram Khaliq
Page # 450-455

ABSTRACT Objective: To evaluate the effectiveness of the American College of Radiology (ACR) Neck Imaging Reporting and Data System (NI-RADS) in the response evaluation of head and neck neoplasms following therapy, utilising contrast-enhanced CT or MRI. Study Design: A descriptive study. Place and ...

Glycaemic Trends and Potential Biomarkers in Painful Diabetic Neuropathy

By Madiha Soban, Iftikhar Ahmed, Zahid Miyan
Page # 456-461

ABSTRACT Objective: To evaluate the relationship between the diabetic profile and human β-nerve growth factor (HβNGF), calcitonin gene–related peptide (CGRP), endothelin-1 (ET-1), and von Willebrand factor (VWF) in distinguishing painful from painless diabetic neuropathy. Study Desig...

CD28 Expression on T Cells as a Biomarker for Allograft Rejection in Renal Transplant Recipients

By Muhammad Aftab Hassan, Muhammad Hussain, Hamid Nawaz Tipu, Muhammad Omair Riaz, Mustajab Alam, Muhammad Zain Arshad
Page # 462-467

ABSTRACT Objective: To evaluate the differences in pre-transplant CD28 expression on T cell subsets between rejectors and non-rejectors of renal transplant, and their potential role in post-transplant outcomes. Study Design: A descriptive cross-sectional study. Place and Duration of the Study: Depar...

Multiscale Embedded Gene Co-Expression Network Combined with Mendelian Randomisation Analysis for the Molecular Pathogenesis of Breast Cancer

By Yang Wang, Rui Xie, Huiming Zhang, Zhicheng Ge
Page # 468-475

ABSTRACT Objective: To integrate multiscale embedded gene co-expression network analysis (MEGENA) and Mendelian randomisation (MR) to identify new pathogenic factors associated with breast cancer (BC). Study Design: A descriptive study. Place and Duration of the Study: Department of General Surgery,...

Effect of Preoperative Oral Carbohydrate Intake on Quality of Recovery in Elderly Patients Undergoing Total Knee Arthroplasty

By Tayfun Et, Betul Basaran, Ibrahim Tuluce, Muhammet Korkusuz, Rafet Yarimoglu, Mehmet Ali Goren
Page # 476-482

ABSTRACT Objective: To assess the effect of preoperative oral carbohydrate intake on the quality of recovery in elderly patients undergoing total knee arthroplasty (TKA), using the Quality of Recovery-15 (QoR-15) questionnaire. Study Design: A randomised, placebo-controlled study. Place and Duration...

Clinical Features and Coinfection Factors of Severe Community-Acquired Pneumonia with Mycoplasma Pneumoniae in Children

By Sheng Wang, Fang Deng
Page # 483-488

ABSTRACT Objective: To characterise the clinical features of children with severe community-acquired pneumonia (CAP) associated with Mycoplasma pneumoniae (Mp) infection and to identify factors influencing polymicrobial coinfections. Study Design: A descriptive study. Place and Duration of the Study...

A Study on the Combined Application of Gastroscopy and the Rapid Urease Test in Paediatric Gastric Disorders

By Xiaoyu Song, Hongzhi Lu, Cuihong Zhao, Tongtong Ma, Dawei Tian, Guoliang Zhang
Page # 489-492

ABSTRACT Objective: To investigate the accuracy, safety, and clinical value of combining gastroscopy with the rapid urease test (RUT) for diagnosing gastric disorders in children. Study Design: A descriptive study. Place and Duration of the Study: Department of Gastroenterology, Maternity and Child ...

Electrolyte Imbalance and Hospital Length of Stay in Children with Acute Gastroenteritis: A Cross-Sectional Analysis at a Secondary Care Hospital

By Syed Muhammad Umair Hamid, Heeramani Lohana, Annayah Usman
Page # 493-497

ABSTRACT Objective: To determine the frequency of electrolyte imbalances in children aged 2-60 months admitted with acute gastroenteritis (AGE), and to evaluate their associations with the length of hospital stay (LOS) at a secondary care hospital. Study Design: An observational study. Place and Dur...

Comparison of Burnout Status of Family Physicians Working in Rural and Urban Areas of Turkiye

By Izzet Fidanci, Hilal Aksoy, Duygu Ayhan Baser
Page # 498-502

ABSTRACT Objective: To compare the levels of burnout among family physicians working in rural and urban areas and to examine factors associated with burnout, including workplace violence, smoking, alcohol consumption, and professional experience. Study Design: A cross-sectional study. Place and Dur...

Residents’ Research Experiences and Barriers: A Qualitative Study to Identify Strategies for Research Skill Enhancement among Residents in a Medical Teaching Institution

By Imtiaz Ud Din, Mehreen Lajber, Aurangzeb Khan
Page # 503-507

ABSTRACT Objective: To explore the research experiences, barriers, and challenges that residents face during residency while completing their research projects, and to identify solutions to overcome these challenges. Study Design: A qualitative study. Place and Duration of the Study: Department of M...

N-acetylcysteine as Prophylaxis Against Contrast-Induced Nephropathy: A Meta-Analysis

By Babar Rafique, Abdul Rehman Arshad, Sohail Sabir, Umair Ijaz, Obaid Ur Rahman
Page # 508-519

ABSTRACT This study aimed to determine the effect of N-acetylcysteine (NAC) in preventing contrast-induced nephropathy. A literature search was carried out in PubMed and Cochrane CENTRAL, and 49 studies were finally included. With oral NAC, there was no difference in the incidence of acute kidney in...

Low-Dose Tamoxifen for Noninvasive Breast Disease: A Meta-Analysis

By Na Wang, Lili Gong, Gang Hu, Chunmei Ye
Page # 520-525

ABSTRACT Tamoxifen is a classic endocrine therapy for breast cancer; however, conventional doses of tamoxifen have serious side effects. Therefore, it is crucial to prioritise the treatment of low-dose tamoxifen. Databases were searched for related studies before November 23, 2023. The overall incid...

Deep Learning-Based Detection of Oral Leukoplakia from Intraoral Images

By Gaye Keser, Hakan Yulek, Filiz Namdar Pekiner
Page # 526-530

ABSTRACT Objective: To assess the effectiveness of deep learning-based diagnostic software in identifying oral leukoplakia (OL) lesions from intraoral patient photographs. Study Design: An observational study. Place and Duration of the Study: Department of Oral and Maxillofacial Radiology, Faculty ...

Antibiotic and Microbiological Profiles in Hidradenitis Suppurativa

By Dilek Mentesoglu, Selda Pelin Kartal
Page # 531-535

ABSTRACT Objective: To investigate the results of swab cultures obtained from lesions of patients with hidradenitis suppurativa (HS) and their antibiotic resistance. Study Design: An observational study. Place and Duration of the Study: Department of Dermatology and Venereology, Ankara Etlik City Ho...

Clinical Presentation and Outcomes of Patients Undergoing Surgery for Thyroid Cancer

By Muhammad Moiz Ullah Khan, Iqbal Hussain Udaipurwala, Shahzad Maqbool, Asif Alam Gul, Muhammad Fahad Wasim, Fatima Siddiqui
Page # 536-540

ABSTRACT Objective: To determine the clinical presentation, subtypes, and surgical outcomes of patients undergoing surgery for thyroid cancer at a tertiary care hospital in Karachi. Study Design: A case series. Place and Duration of the Study: Department of ENT Head and Neck Surgery, PNS Shifa Hospi...

An Audit of Morbidity and Mortality among Hospitalised Neonates in the Neonatal Intensive Care Unit of a Tertiary Care Teaching Hospital

By Komal Khadim Hussain, Sehrish Masood, Shahla Tariq
Page # 541-546

ABSTRACT Objective: To identify trends in neonatal mortality and morbidity among neonates admitted to neonatal intensive care unit (NICU). Study Design: A descriptive study. Place and Duration of Study: Department of Paediatric Medicine, Services Institute of Medical Sciences and Services Hosp...

Significance of Herbs in the Dental World

By Ihtesham Ul Haq, Waqar Un Nisa
Page # 547-549

ABSTRACT Herbs have historically been used in dentistry. For instance, peppermint oil and clove oil have been used to alleviate a toothache by soaking a cotton ball in the oil and subsequently placing it in the cavity or applying it directly to the affected tooth. Dental caries and periodontal disea...

Bridging the Gap: Digital Adaptation in Low-Resource Settings

By Talat Zehra, Anil Parwani, Sarosh Moeen, Muhammad Mubarak
Page # 550-552

ABSTRACT The fields of digital pathology (DP) and computational pathology (CP) are transforming traditional histopathology by replacing manual microscope-based examinations with digital tools. While DP uses digitised whole slide images (WSIs) for research, education, knowledge sharing, telepathology...

Correlation of Imaging Features with Pathological Subtypes and Clinical Risk Factors in Adenoid Cystic Carcinoma of the Head and Neck

By Wanyi Shao, Yingyu Dai, Shan Huang, Yonghao Liu
Page # 553-555

ABSTRACT Adenoid cystic carcinoma is relatively rare in the head and neck, and the early imaging features are not specific, so the misdiagnosis rate is high. Through multimodal imaging examinations, the imaging features of various pathological subtypes were analysed, combined with clinical mani...

A Rare Cause of Acute Abdomen: Intestinal Malrotation Complicated by Internal Hernia in an Adult

By Yaomeng Chen, Shuang Gao, Xinle Chi
Page # 556-557

Spontaneous Intracranial Hypotension Syndrome

By Li Lin, Xinglin Wen
Page # 558-558

Surgical Management of Giant Retroperitoneal Tumours: Insights from Three Cases with Technical Considerations

By Lingyu Guo, Yuquan Xue
Page # 559-560

Beyond the Surface:
Re-evaluating the Assumptions of Patient-Reported Outcomes in Oncology

By Amna Khan, Sumaira Gulzar, Sundus Dadan
Page # 561-563

Post-Traumatic Osteonecrosis of the Wrist with Secondary Necrotic Infection: Successful Primary Debridement and Antibiotic Bone Cement Treatment

By Fei Chi, Wendong Xie
Page # 564-565

Penile Mass in Multivisceral Alveolar Echinococcosis: A Case Report of Highly Suspected Disseminated Infection

By Baixin Li, Zizhi Wei, Chengde Ren
Page # 566-567

Corrigendum for: Artificial Intelligence-Based Digital Image Analysis for Assessing Ki67, P53, and PHH3 Expression in Glioblastoma Multiforme

By Tuba Devrim, Gamze Erkilinc, Saniye Sevim Tuncer
Page # 568-568

This is with reference to the article titled "Artificial Intelligence-Based Digital Image Analysis for Assessing Ki67, P53, and PHH3 Expression in Glioblastoma Multiforme" published in JCPSP 2026, Vol. 36 (02): 153-7. doi: 10.29271/jcpsp.2026.02.153. It is to be informed that, during the e...