Journal of College of Physicians and Surgeons Pakistan (JCPSP), is the prestigious, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.

The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.

Latest Articles

Volume 30 | Issue 6 | June 2020

A New FDA-approved Antibiotic for Drug-resistant Tuberculosis Treatment

By Faiza Ahmed, Kim Andrews, Dipali Arshad, Praneeth Nekuri

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Levels of Ischemia: Modified Albumin in Patients Undergoing On-pump Coronary Artery Bypass

By Kadir Kaan Özsin, Abdullah Burak Balci, Umut Serhat Sanri, Orhan Guvenc, Senol Yavuz

ABSTRACT Objective: To investigate the effect of ischemia-modified albumin (IMA) during cardiopulmonary bypass (CPB). Study Design: Observational study. Place and Duration of Study: Department of Cardiovascular Surgery, Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey, between January an...

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Role of TLR4/NF-κB Signalling Pathway in Pulmonary Arterial Hypertension in Patients with Chronic Obstructive Pulmonary Disease

By Zhi Tong Zuo, Ya Ma, Yan Sun, Cui Qing Bai, Hai Yue Zhou, Bao Hua Chen

ABSTRACT Objective: To determine the role of toll-like receptor 4 (TLR4)/ nuclear factor kappa B (NF-κB) signalling pathway in pulmonary arterial hypertension (PAH) in patients with chronic obstructive pulmonary disease (COPD). Study Design: An experimental study. Place and Duration of Study: ...

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Glutathione S-Transferase Theta 1 / Mu 1 Null Genotype and Risk of Development of Actinic Keratosis in Pakistani Population

By Muhammad Imran Bajwa, Amena Rahim, Muhammad Afzal, Amna Mahmood

ABSTRACT Objective: To assess the frequency and association of Glutathione S-Transferase Theta 1 and Glutathione S-Transferase Mu 1 null genotypes in development of actinic keratosis (AK) in a group of Pakistani population. Study Design: Case-control analytical study. Place and Duration of Study: De...

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Efficacy of Low Dose Naltrexone in Psoriasis

By Sidra Khan, Rabia Ghafoor, Sana Kaleem

ABSTRACT Objective: To determine the efficacy of low dose naltrexone in the patients of psoriasis. Study Design: Non-randomised clinical trial. Place and Duration of Study: Department of Dermatology, Jinnah Postgraduate Medical Centre, Karachi from January to July 2019. Methodology: All patients of...

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Scheuermann’s Disease as a Risk Factor for Lumbar Disc Herniation Recurrence

By Yan Ding, Shiqiao Lv, Guangrun Li, Shengjie Dong, Xuri Sun, Yunzhen Chen

ABSTRACT Objective: To verify whether Scheuermann’s disease (SD) is a risk factor for patients with recurrent lumbar disc herniation (rLDH) than in patients without recurrence. Study Design: Case-control study. Place and Duration of Study: Department of Orthopaedics, Yantaishan Hospital, China...

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Prognostic Importance of Metastatic Site in Intermediate-risk Group Metastatic Renal Cell Cancer Treated with Tyrosine Kinase Inhibitors

By Cengiz Karacin, Irem Bilgetekin, Fatma Bugdayci Basal, Omur Berna Oksuzoglu

ABSTRACT Objective: To determine the prognostic importance of the metastatic site in metastatic renal cell cancer (mRCC) patients in the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) intermediate-risk. Study design: Observational study. Place and Duration of Study: Departm...

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Comparison of Tumor Volume Dependent Mean Diameter with the Longest Diameter and Tumor Volume in Assessing Axillary Lymph Nodes in Breast Cancer

By Mehmet Kubat, Zülfikar Karabulut

ABSTRACT Objective: To investigate the effectiveness of tumor volume dependent mean diameter (Rmax) in determining axillary lymph node metastasis positivity instead of the largest diameter (Dmax) in breast cancer. Study Design: Descriptive study. Place and Duration of Study: Department of General ...

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Correlation between Clinical Factors and Prognosis in Newly Diagnosed Multiple Myeloma

By Xiao-Qing Zhao, Shu-Ying Zhao, Wen-Xin Chen, Xiao-Wei Liu, Huai-Xiu Yan, Yong-Ji Lou

ABSTRACT Objective: To explore the correlation between clinical factors and the prognosis of multiple myeloma (MM). Study Design: A cohort study. Place and Duration of Study: At the Third Affiliated Hospital of Inner Mongolia Medical University, Mongolia from January 2014 to December 2018. Methodol...

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Vascular Occlusion Role in the Etiopathohegenesis of Idiopathic Sudden Sensorineural Hearing Loss: Risk Analysis with Hematological Parameters

By Selcuk Yildiz, Sema Zer Toros

ABSTRACT Objective: To evaluate the concomittant metabolic disorders, mean platelet volume (MPV), and neutrophil to lymphocyte ratio (NLR) in patients with idiopathic sudden sensorineural hearingloss (SSNHL) in comparison to healthy controls. Study Design: Case-control study. Place and Duration of ...

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Mortality Caused by Late-onset Sepsis in Very Low Birth Weight Infants: Risk Analysis and the Performance of Diagnostic Tools

By Hakan Ongun, Meltem Demir

ABSTRACT Objective: To assess the risk on late-onset sepsis attributed mortality in very low birth weight (VLBW) infants.    Study Design: Observational study. Place and Duration of Study: Level-III Neonatal Intensive Care Unit, İstinye University, Antalya Medical Park Hospital, Tur...

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Diagnostic Value of Musculoskeletal Ultrasound in Rheumatoid Finger Arthritis

By Xiaofeng Wang, Guo Qian, Hongbo Duan

ABSTRACT Objective: To determine the value of musculoskeletal ultrasound (MSUS) in evaluating the pathological features and inflammatory lesions of rheumatoid finger arthritis. Study Design: A comparative study. Place and Duration of Study: Ningbo No. 6 Hospital, China, from September 2017 to Febru...

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Correlation between Overactive Bladder Syndrome and Severity of Coronary Artery Disease in Postmenopausal Women

By Bahar Yuksel, Faruk Özgör, Murat Şahan, Semih Ozturk, Mehmet Mustafa Can, Omer Sarilar

ABSTRACT Objective: To analyse the correlation of overactive bladder (OAB) and severity of coronary artery disease (CAD) by using Gensini score in postmenopausal women. Study Design: Observational correlation study design. Place and Duration of Study: Haseki Training and Research Hospital, Istanbul...

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Post-cardiac Surgery Chylopericardium

By Shi-Min Yuan

ABSTRACT Post-cardiac surgery chylopericardium is a rare complication. This systematic review included 87 articles with 119 patients of post-cardiac surgery chylopericardium. Chylopericardium developed after operations for congenital heart defect more than those for acquired heart disease, and more ...

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Reliability and Validity of WATCH: Warwick Assessment InsTrument for Clinical TeacHing

By Sonia Ijaz Haider, Khalid Masood Gondol, Muhammad Tariq, Muhammad Furqan Bari, Iqbal Azam

ABSTRACT Objective: To determine the reliability, validity, feasibility, acceptability and perceived educational impact of WATCH: Warwick Assessment insTrument for Clinical teacHing among doctors in Pakistan. Study Design: Cross-sectional research study. Place and Duration of Study: The College of P...

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Acute Side Effects with High Dose Rate Computed Tomography-guided Three-dimensional Brachytherapy in Carcinoma Cervix

By Sadia Sadiq, Abubaker Shahid, Misbah Masood, Rab Nawaz Maken, Amira Shami, Ismat Fatima

ABSTRACT: Objectives: To determine the frequency and grades of acute side effects with three-dimensional brachytherapy in carcinoma cervix using RTOG/EORTC acute radiation morbidity scoring criteria. Study Design: Descriptive study. Place and Duration of Study: Department of Radiotherapy, Institute ...

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Expression of p53 Protein in Prostate Carcinoma and its Correlation with Gleason Grade

By Zakia Wahid, Rozina Jaffer, Sobia Khalid, Haseeb Ahmed Khan, Sabiha Riaz

ABSTRACT Objectives: To determine the correlation of p53 expression with Gleason score in prostate cancer. Study Design: Descriptive study. Place and Duration of Study: Department of Pathology, Fatima Memorial Hospital, Lahore; from January 2014 to August 2016. Methodology: Thirty-seven samples of ...

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Mechanical Jaundice and Bile Duct Stricture Caused by the Migration of Endoclip and Silk Suture Material into the Common Bile Duct

By Şükrü Çolak, Hasan Bektaş, Bünyamin Gürbulak

ABSTRACT It is quite rare the migration of metal clips and silk suture materials into the common bile duct (CBD) that were used for the closure of cystic duct in conventional or laparoscopic cholecystectomy. The most common cause of postoperative jaundice is unrecognised or overlooked stones in...

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Mesenteric Lipoma with Volvulus: A Rare Cause of Acute Abdomen in a Child

By Hamza Malik, Bilal Mirza, Nabila Talat, Waseem Zia, Anum Manzoor

ABSTRACT Lipoma is benign tumor of mature fat cells and is reported to develop anywhere in the body, e.g. trunk and extremities; however, lipoma in the mesentery of gut is rare, particularly in children. Mesenteric lipomas may be asymptomatic or may present with acute abdomen by leading to volvulus ...

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Harlequin Fetus in a Twin Pregnancy: An Extremely Rare Presentation

By Arfan ul Bari, Syed Umair Ahmed Najmi

ABSTRACT Harlequin ichthyosis (HI) is a rare fatal type of congenital ichthyosis with autosomal recessive inheritance pattern. We report an uncommon presentation of a case of HI in a neonate, who was the second outcome of the dizygotic twin pregnancy of a Pakistani female. Whilst the first twin rema...

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Late Diagnosis of Paracetamol Poisoning is Always Lethal in Young Adult

By Sehrish Naz, Safia Fatima, Muhammad Aamir

ABSTRACT Acetaminophen has a remarkable safety profile when prescribed in proper therapeutic doses, but hepatotoxicity can occur when misused or after an overdose. The principal toxic metabolite of acetaminophen is N-acetyl-p-benzoquinone imine (NAPQI). Toxicity should be considered in all suspiciou...

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ROC Curve in Evaluation of Diagnostic Value of Serum 25-hydroxyvitamin-D for PCOS with Depression

By Ying Liu, Qianhui Qi

ABSTRACT The objective of this study was to apply receiver operating characteristic (ROC) curve to evaluate diagnostic value of serum 25-hydroxyvitamin-D [25-(OH)D] for polycystic ovarian syndrome (PCOS) combined with depression. Serum 25-(OH)D level was determined in 106 PCOS patients. Beck depress...

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Association of Programmed Death Ligand-1 Overexpression with the Grade and Stage of Oral Squamous Cell Carcinoma

By Zeeshan Mustafa Qureshi, Samina Qamar

ABSTARCT Programmed Death Ligand-1(PD-L) expression can be used to predict targeted therapy against PD-L1/PD-1 pathway in oral squamous cell carcinoma (OSCC). Forty-nine patients were included in the study. Out of the total, 42 well differentiated tumor 3 (7.1%) exhibited strong PD-L1 membranous and...

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A Case of Breakthrough Pain Management with Subcutaneous Fentanyl Administration in a Female Child

By Irum Ghafoor, Adeel Siddiqui, Haroon Hafeez, Hafiz Muhammad Usman

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Mesenteric Hematoma: Challenges in Diagnosis and Management

By Kamal Kant Sahu, Ajay Kumar Mishra, Amos Lal, Iryna Chastain

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Twin Pregnancy Complicated by Intrauterine Death of One Fetus and Herniated Bowel Loops Over Gravid Uterus

By Malika Hameed, Khalid Ahsan

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Pistol Bullets: Not Fired But Ingested by a Patient of Borderline Personality Disorder

By Sana Khan, Usama bin Zubair, Rashid Qayyum, Nomita Sohail

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Clinical Audit a Valuable Tool for Quality Improvement of Care: Radiation Oncologists’ Perspective

By Sehrish Abrar, Ahmed Nadeem Abbasi, Maria Tariq

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A Dangerous Octopus Fishing: Kounis Syndrome Following an Octopus Bite

By Riccardo Scagliola, Gianluca Secchi, Claudio Brunelli

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