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Volume 33, 12 Issues, 2023

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.

The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.

Important Announcement for Authors

"A companion journal of JCPSP (the official journal of CPSP) has been launched by the name of JCPSP Case Reports. Submission of Case Reports is now open."
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Latest Articles
Volume 33 | Issue 11 | November 2023
Near-Infrared Spectroscopy (NIRS) for Non-Invasive Diagnosis

By Saeeda Baig

The Effect of Pirfenidone on Peyronie Plaques and Erectile Function in a Peyronie’s Rat Model

By Gokhan Cevik, Atinc Tozsin, Ebru Tastekin, Murat Dursun, Tevfik Aktoz, Ates Kadioglu

ABSTRACT Objective: To investigate the anti-fibrotic effects of pirfenidone on Peyronie’s disease in an experimental rat model with intracavernosal injection of TGF-β and whether pirfenidone improves erectile function. Study Design: Experimental study. Place and Duration of the Study: Fac...

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High, Low, and Minimal Flow Anaesthesia Management: Effects on Oxygen Reserve Index and Arterial Partial Oxygen Pressure

By Ramazan Dastan, Hale Kefeli Celik, Zahide Doganay

ABSTRACT Objective: To determine the oxygen reserve index (ORI) as a supporting parameter to the arterial partial oxygen pressure (PaO2) in blood gases in hypoxia and hyperoxia monitoring with different fresh gas flows (FGF) in patients undergoing abdominal surgery. Study Design: Randomised controll...

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Pulmonary Artery Diameter Measurement and Semiquantitative Visual Scoring with Q-SPECT-CT in Acute Pulmonary Embolism

By Guler Silov, Asli Ayan

ABSTRACT Objective: To investigate whether pulmonary artery diameters obtained from lung perfusion single-photon emission computed tomography-computed tomography (SPECT-CT) images and semiquantitative visual scoring (SVS) could serve as predictors of chronic pulmonary thromboembolic disease (CPTED) ...

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Effect of Mesoappendix Volume on Preoperative Pain of Acute Appendicitis

By Ali Cihat Yildirim, Huseyin Emre Arslan, Sezgin Zeren, Mehmet Fatih Ekici, Mustafa Cem Algin, Ozlem Arik

ABSTRACT Objective: To investigate the relationship between preoperative pain scores and the mesoappendix volume and the presence of complications in patients with acute appendicitis. Study Design: Cross-sectional observational study. Place and Duration of the Study: Department of General Surgery at...

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Can the Modified Systemic Inflammation Score Predict Complicated Appendicitis?

By Enver Okan Hamamci, Sadettin Er, Tezcan Akin, Sukru Melih Bayazatli, Huseyin Berkem, Erdinc Cetinkaya

ABSTRACT Objective: To differentiate between complicated and uncomplicated acute appendicitis using the modified systemic inflammation score (mSIS) preoperatively. Study Design: Observational study. Place and Duration of the Study: The Emergency Surgery Service of General Surgery Clinic of Ankara Bi...

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Effect of Reinforced Video by WeChat on Adenoma Detection Rate for Colonoscopy

By Xia Li, Wei Yang, Hui Zhao, Wenquan Lan, Gang Xu, Yuanfa Li

ABSTRACT Objective: To evaluate the influence of reinforced educational video through smartphone WeChat on adenoma detection rate (ADR). Study Design: Randomised controlled study. Place and Duration of the Study: Department of Gastroenterology, Xiantao First People’s Hospital affiliated to ...

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Frequency of TP53 Mutation in B-Cell Chronic Lymphocytic Leukaemia and its Association with Lymphocyte Doubling Time

By Syeda Mah Ali, Syed Muhammad Irfan, Naila Raza

ABSTRACT Objective: To determine the frequency of TP53 mutation at diagnosis of B-cell Chronic Lymphocytic Leukaemia (B-CLL) in Pakistani patients, and to investigate whether lymphocyte doubling time (LDT) of less than 1 year could be used as a surrogate marker for TP53 mutation. Study Design: A cro...

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Oxidative Stress and Lipid Peroxidation in NAFLD with and without Type 2 Diabetes Mellitus

By Anoshia Javed, Khadija Mehboob, Amir Rashid, Asifa Majid, Sumbal Khan, Zunaira Ali Baig

ABSTRACT Objective: To compare superoxide dismutase 1 (SOD 1) and malondialdehyde (MDA) levels along with biochemical parameters in patients of non-alcoholic fatty liver disease (NAFLD) with and without Type 2 diabetes mellitus. Study Design: Cross-sectional comparative study. Place and Duration of ...

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Laboratory Safety Climate Assessment and its Correlation with Safety Procedures Amongst Staff of a Reference Clinical Laboratory

By Maimoona Roghani, Zujaja Hina Haroon, Muhammad Usman Munir, Sobia Irum Kirmani, Muhammad Anwar, Muhammad Younas

ABSTRACT Objective: To compare and correlate safety climate standards and safety practices among different subspecialities of pathology. Study Design: Cross-sectional study. Place and Duration of the Study: The study was conducted at Armed Forces Institute of Pathology, Rawalpindi, Pakistan, from Fe...

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Mechanical Epithelial Debridement versus Transepithelial Phototherapeutic Keratectomy Followed by Accelerated Corneal Collagen Crosslinking for Progressive Keratoconus

By Sadia Humayun, Aaiza Tahir, Mazhar Ishaq, Sabahat Arzoo, Aizaz Ali Shah

ABSTRACT Objective: To compare the visual and topographic outcomes between mechanical epithelial debridement followed by accelerated corneal collagen cross linking (CXL) vs. transepithelial phototherapeutic keratectomy followed by accelerated CXL for treatment of progressive keratoconus. Study Desig...

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The Impact of the COVID-19 Pandemic on the Diagnosis and Treatment Characteristics of Operated Lung Cancer Patients

By Haci Arak, Omer Eronat, Ilkay Dogan, Erva Sehla Aydin, Aydin Aytekin

ABSTRACT Objective: To analyse the impact of the COVID-19 pandemic on the diagnostic method, disease stage, treatment modalities, and survival of operated non-small cell lung cancer (NSCLC) patients. Study Design: Descriptive study. Place and Duration of the Study: Department of Oncology, Gaziantep ...

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Systemic Inflammatory Index: A Novel Biomarker for Predicting the Progression in Active Surveillance in Patients with Prostate Cancer

By Levent Ozcan, Memik Omur, Emre Can Polat, Caner Baran, Ahmet Boylu, Alper Otunctemur

ABSTRACT Objective: To investigate active surveillance (AS) for patients with prostate cancer to show the systemic inflammatory index (SII) progression and to evaluate whether SII will be an AS criterion in PCa patients. Study Design: Descriptive study. Place and Duration of the Study: Department of...

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Arthroscopic Stabilisation in Anterior Shoulder Instability: An Analysis of Mid-term Outcome

By Muhammad Usama, Muhammad Umer Faheem, Haseeb Hussain, Zain Muhammad, Ammar Dogar, Shahzad Javed

ABSTRACT Objective: To assess the clinical outcome of arthroscopic stabilisation for recurrent anterior glenohumeral joint dislocations. Study Design: Case series. Place and Duration of the Study: Ghurki Trust Teaching Hospital, Lahore, from May 2018 to December 2022. Methodology: Fifty-two patie...

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Diagnostic Accuracy of Serum Presepsin as Biomarker of Bacterial Sepsis in Paediatric Patients

By Maham Shakoor, Rehma Dar, Komal Javed

ABSTRACT Objective: To determine the diagnostic accuracy of serum Presepsin for bacterial sepsis in paediatric patients keeping blood culture as the gold standard test.                       ...

Effects of Physical Activity on Thyroid Stimulating Hormone Levels in Obese Metabolic Syndrome Patients: A Meta-Analysis

By Batool Hassan, Basit Ansari, Sumaira Farooqui

ABSTRACT Metabolic syndrome is a combination of multiple disorders that predispose an individual to risk of diabetes, obesity, cardiovascular diseases (CVDs), cerebrovascular accidents (CVAs), and insulin-resistance. Hypothyroidism is the most prevalent metabolic disorder causing obesity, followed b...

Improving Kyphotic Postures and Neck Pain in Young Adults: A Meta-Analysis of Exercise-Based Interventions

By Mehjabeen Saeed, Fatima Zehra, Sehrish Aslam

ABSTRACT The study aimed to review the findings concerning the effects of exercises on Cobb angle and pain in patients suffering from cervical pain caused by thoracic kyphosis. Two investigators separately conducted a systematic review of the electronic literature from 2018 till 2022. PubMed, MEDLIN...

Development and Evaluation of a Peer Mentoring Programme for Postgraduate Medical Residents in Pakistan: A Pilot Study

By Sonia Ijaz Haider, Qamar Riaz, Muhammad Furqan Bari

ABSTRACT Objective: To develop, implement, and evaluate the impact of one-year peer mentoring programme for postgraduate medical residents. Study Design: Mixed methods. Place and Duration of the Study: The Aga Khan University, Karachi, from January 2019 to December 2020. Methodology: A survey was ...

Effect of Upfront Docetaxel in De Novo Metastatic Castration-Sensitive Prostate Cancer Patients with Gleason Grade Group 5

By Serkan Yildirim, Cengiz Yilmaz

ABSTRACT Objective: To investigate whether adding docetaxel chemotherapy to androgen deprivation therapy is effective regarding progression-free and overall survival in patients with de novo metastatic castration-sensitive prostate cancer patients with Gleason Grade Group 5 (Gleason scores 9 and 10)...

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Comparison of the Locking Intramedullary Nailing, Single Plate and Double Plate Osteosynthesis in Treatment of Humerus Shaft Fractures

By Haci Bayram Tosun, Sancar Serbest, Mehmet Mete Yasar, Abuzer Uludag, Galip Ersoz

ABSTRACT Objective: To compare the clinical and radiographic outcomes between patients treated with single plate osteosynthesis, double plate osteosynthesis, and antegrade locked intramedullary nailing (IMN) in treatment of humerus diaphyseal fractures. Study Design: Descriptive study. Place and Du...

Nasal Morphology as an Indicator of Maxillomandibular Skeletal Pattern

By Asma Faryal, Attiya Shaikh

ABSTRACT Objective: To determine the correlation of nasal morphology with maxillary and mandibular patterns. Study Design: Descriptive cross-sectional study. Place and Duration of the Study: Department of Orthodontics, Liaquat College of Medicine and Dentistry and Qamar Dental Hospital, Karachi, Pak...

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Differences Between Conventional and Newer Anthropometric Measures Among Individuals with and without Fatty Liver Disease

By Sikandar Hayat Khan, Ayesha Hafeez, Yasser Khan, Nayyar Chaudhry, Usama Bin Khalid, Shahrukh Shah

ABSTRACT A cross-sectional analysis was conducted to compare conventional and emerging anthropometric measures among male participants with and without fatty liver disease (FLD). The objective was to assess differences and diagnostic efficiency of anthropometric-parameters using receiver operating c...

The Effect of Regular Exercise and its Duration on Metabolic Parameters

By Olgun Goktas, Canan Ersoy

ABSTRACT Regular exercise is crucial for regulating metabolic parameters. This retrospective study aimed to evaluate the effects of regular exercise duration on glycaemic and metabolic parameters, insulin resistance, and atherogenic indices in individuals attending a single-family health centre. A t...

Total Intravenous Anaesthesia vs. Inhalational Agents in a Patient with Autoimmune Liver Disease

By Javeria Bakhtawar, Sheema Siraj, Hussaini Sulaiman

Safety Trial of Normothermia on Cardiopulmonary Bypass

By Wardah Saleem, Furqan Ahmed Raheel, Fayaz Iqbal

Need for Innovations in Maxillofacial Prosthodontics in Pakistan

By Hina Zafar Raja, Muhammad Nasir Saleem

Thrombocytopenia Caused by Iron Infusion in a Patient with End-Stage Kidney Disease

By Shaheen Bibi, Kunwer Naveed, Abdul Haq

Research Integrity, Governance, and Misconduct in Pakistan: Some Proposed

By Farooq Azam Rathore, Fareeha Farooq

Recurrence of Submandibular Adenocarcinoma with Intra-cranial Metastasis as the First Symptom

By Dagang Liu, Ying Wang