Journal of College of Physicians and Surgeons Pakistan (JCPSP), is the prestigious, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Important Announcement for Authors

"As a large number of case reports are awaiting publication, JCPSP has decided to stop acknowledging Case Reports for a certain period of time until the backlog is cleared. Therefore, case reports are regretted from processing".

Latest Articles
Volume 31 | Issue 5 | May 2021
Impact of Doctor Role Models on Professional Development of Medical Students

By Maria Khan, Brekhna Jamil, Fatima Muhammad

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Neurological Outcomes of Normothermia versus Targeted Temperature Management in Post-cardiac Arrest Syndrome

By Havva Kocayigit, Kezban Ozmen Suner, Burak Kaya, Yakup Tomak, Ayça Taş Tuna, Ali Fuat Erdem

ABSTRACT Objective: To determine the neurological outcome of targeted temperature management (TTM)for patients scoring lower than 8 on the Glasgow coma scale (GCS) upon return of spontaneous circulation (ROSC) after cardiac arrest. Study Design: Retrospective cohort study. Place and Duration of Stud...

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Comparing the Efficacy of Patelet-rich Plasma (PRP) versus Tranexamic Acid (4mg/mL) as Intradermal Treatments of Melasma

By Maryam Mumtaz, Tahir Hassan Chandio, Mohammad Khurram Shahzad, Nazia Hanif, Sarah Anwar, Saira Rafique

ABSTRACT Objective: To compare the efficacy of intradermal platelet-rich-plasma vs. intradermal tranexamic acid in treatment of melasma. Study Design: Non-randomised controlled trial. Place and Duration of Study: Sheikh Zayed Hospital, Rahim Yar Khan from 1st October 2019 to 30th April 2020. Meth...

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Correlation of the Radiological Emphysema Score of Chronic Obstructive Pulmonary Disease Patients with Clinic Parameters

By Merve Yumrukuz Senel, Serap Duru Akcali, Alper Dilli, Bahar Kurt

ABSTRACT Objective: To evaluate the association between the degree of emphysema on computed tomography (CT) images and disease severity, in order to predict the clinical characteristics of patients with chronic obstructive pulmonary disease (COPD). Study Design: Cross-sectional, observational study...

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Relationship between Lymph Node Metastasis and a Low 18F-FDG PET/CT Axillary SUVmax Value in Breast Cancer

By Ozgur Kulahci, Oktay Irkorucu, Emel Kocyigit Deveci, Zeynel Abidin Tas

ABSTRACT Objective: To evaluate breast cancer patients with low F18-fluorodeoxy-glucose positron emission tomography/computed tomography scan (FPET) of axilla standardised maximum uptake value (SUVmax) along with their histopathological findings regarding axillary lymph node metastasis (LNM). ...

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The Relationship between Third-generation TSH Receptor Antibody Positivity and Cumulative Methimazole Dose Used until Remission in Graves' Disease

By Serhat Ozçelik, Mehmet Celik, Aski Vural, Bunyamin Aydin, Hulya Gozu

ABSTRACT Objective: To determine the relationship between the positivity of third-generation TSH receptor antibody (TRAb) at the time of diagnosis and the cumulative methimazole dose used until remission in patients with Graves’ disease. Study Design: Cross-sectional, descriptive study. Place...

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IVF Outcomes of Microdose Flare-up, GnRH Antagonist, and Long Protocols in Patients having a Poor Ovarian Response in the First Treatment Cycle

By Erhan Demirdağ, M. Funda Cevher Akdulum, Ismail Guler, Yuksel Oguz, Ahmet Erdem, Mehmet Erdem

ABSTRACT Objective: To compare the IVF outcome of patients assumed to be poor responders before their first cycle treated by microdose flare-up or GnRH antagonist protocols with patients who had a poor ovarian response after their first cycle stimulated with long GnRH protocol. Study Design: Observ...

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Association of Serum Hyaluronic Acid and Laminin with Polymerase Chain Reaction Findings in Hepatitis C Patients

By Tahir Asad, Muhammad Aamir, Zujaja Hina Haroon, Sobia Irum Kirmani, Muhammad Usman Munir, Syed Raza Jaffar

ABSTRACT Objectives: To find the association of serum hyaluronic acid and laminin levels with polymerase chain reaction (PCR) results in hepatitis C sero-positive patients; and the correlation among viral load, serum hyaluronic acid, and serum laminin levels. Study Design: Cross-sectional descriptiv...

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Cyberknife Radiosurgery in Hepatocellular Carcinoma

By Bakhtawar Memon, Shazia Kadri, Nimrah Sultana, Kamran Saeed, Naveed Ahmed, Tariq Mahmood

ABSTRACT Objective: To determine the outcome of Stereotactic Body Radiation Therapy (SBRT) and its prognostic factors among hepatocellular carcinoma (HCC) patients. Study Design: Descriptive study. Place and Duration of Study: Department of Radiology and Cyberknife Robotic Radiosurgery, Jinnah Postg...

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Could C-Reactive Protein/Albumin Ratio be an Indicator of Activation in Axial Spondyloarthritis?

By Melih Pamukcu, Tugba Izci Duran

ABSTRACT Objectives: To evaluate the relationship of C-reactive protein (CRP)/albumin ratio (CAR), neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio with Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in axial spondyloarthritis (Ax-SpA). Study Design: Cross-sectional stu...

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Effect of Very Advanced Maternal Age on Pregnant Women and Fetuses

By Mingyan Zhang, Yuxiao Wang, Xiaoying Qi

ABSTRACT Objective: To compare the difference in the effect on pregnant women and fetuses between very advanced maternal age (age of or over 45 years) and other ages (age below 45 years). Study Design: A descriptive study. Place and Duration of Study: Changyi People's Hospital, China, from June...

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Predictive Significance of Ki-67 and Platelet Lymphocyte Ratio in Patients with Gastric Cancer Receiving Neoadjuvant FLOT Chemotherapy

By Hatice Yilmaz, Guzin Demirag, Yurdanur Sullu, Ali Yilmaz

ABSTRACT Objective: We aimed to determine the predictive significance of Ki-67 and platelet lymphocyte ratio (PLR) in patients with gastric cancer (GC), who received fluorouracil, leucovorin, oxaliplatin, docetaxel (FLOT) as neoadjuvant chemotherapy (NAC). Study Design: Descriptive study. Plac...

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Expressions of Putative Cancer Stem Cell Markers, CD44 and CD133, are Correlated with Pathological Tumour Stage in Gastric Adenocarcinoma

By Selma Erdogan Duzcu, Hesna Muzeyyen Astarci, Nur Tunc, Cetin Boran

ABSTRACT Objective: To analyse partial and total gastrectomy specimen in items of immunohistochemical staining of the stem cell CD44 and CD133; and to determine their relationship to pathological stage, other clinicopathological prognostic parameters, and their predictive value. Study Design: Derscr...

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Wii Fit for Balance Training in Elderly: A Systematic Review

By Ayesha Afridi, Farooq Azam Rathore, Shaikh Nabi Bukhsh Nazir

ABSTRACT Falls due to poor balance are common in elderly people and can cause fractures, head injury, soft tissue trauma; and may even result in death from these complications. Balance training is one of the strategies used to prevent falls among the elderly population. Wii Fit is a new technologica...

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P-wave Duration and Dispersion in Lone Obesity

By Mehmet Cosgun, Isa Sincer, Mehmet Inanir, Emrah Erdal, Asli Kurtar Mansiroglu, Yilmaz Gunes

ABSTRACT Objective: To assess P-wave duration and dispersion (PD) in morbidly obese young subjects who do not have co-associated atrial fibrillation (AF) risk factors, such as hypertension, diabetes, atrial enlargement and diastolic dysfunction. Study Design: An observational cross-sectional study. ...

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Frequency of Hypomagnesaemia following Total and Near-total Thyroidectomy and its relationship with Hypocalcaemia

By Sana Viqar, Tasleem Akhtar, Nadeem Ikram, Naeem Zia

ABSTRACT Objective: To determine the frequency of hypomagnesaemia in patients undergoing thyroidectomy and evaluate its relationship with postoperative hypocalcaemia. Study Design: Observational, cross-sectional study. Place and Duration of Study: Surgical Unit 1, Benazir Bhutto Hospital, Rawalpindi...

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Poppy Intoxication in Infants and Children: Hazards of a Folk Remedy

By Sumera Akram, Mohammad Fazil, Kiramat Ullah

ABSTRACT Objective: To study the clinical and laboratory profile in infants and children presented in the tertiary care hospital with poppy intake and to compare the profile between those who survived with those who died. Study design:  Observational study. Study Place and Duration: Department ...

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Management of a Firmly Lodged Endotracheal Tube: A Case of High Quality Communication

By Gabrielle Thompson, Mark Harrison, Hassan Ahmad

ABSTRACT This article describes a case of endotracheal tube firmly lodged in the trachea of a patient due to denuded subglottic cartilage and subglottic swelling. A 30-year female, who had a number of previous intubation episodes, presented with reduced consciousness and was intubated in order to pr...

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Management Strategy for a Patient with Coexistence of Meningioma and Paraophthalmic Aneurysm

By Burak Kinali, Mehmet Senoglu, Evren Sandal, Gauravjot Sandhu, Ali Karadag

ABSTRACT The coexistence of intracerebral aneurysm and meningioma is a rare occurrence. There is no consensus about the treatment options. We aim to present a case of a 61-year female admitted to this clinic with persistent headache and loss of vision in both eyes, especially on the left. Radiologic...

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Adenocarcinoma in Orthotopic Neobladder 19 Years After Radical Cystoprostatectomy

By Orkunt Ozkaptan, Alkan Cubuk, Erdinc Dincer, Osman Murat Ipek

ABSTRACT Radical cystectomy and orthotopic neobladder are the most preferred surgical approaches for the treatment of invasive bladder cancer. Secondary tumour of ileum on neobladder is very rare. We report a 67-year man complaining of hematuria with the history of ileal neobladder for 19 years.&nbs...

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Spectacle Cord-retained Oculo-Orbital Prosthesis

By Shefali Goel, Saumyendra V. Singh, Neetu Singh, Deeksha Arya, Pooran Chand

ABSTRACT Retention of an orbital prosthesis plays a key role in treatment success and patient acceptance as does aesthetics. Though numerous retentive aids are available such as implants, adhesives, etc, the cost, surgical aspect, difficulty of use and allergic potential may compromise efficiency....

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Painless Posterior Scleritis: A Rare Presentation

By Summaya Khan, Mahum Faheem, Imran Basit, Ammarah Ashraf

ABSTRACT Posterior scleritis is an underdiagnosed condition due to its rarity and is frequently misdiagnosed due to its varied presentation.1 Therefore, it is imperative to know that it can present clinically as exudative retinal detachment, proptosis, disc oedema, choroidal folds, subretinal mass, ...

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Mature Orbital Teratoma

By Rabia Chaudhry, M. Nasar Qamar, Areej Riaz

ABSTRACT Orbital teratoma is a rare tumour that is composed of tissues derived from all three germ cell layers. It presents, in otherwise, healthy neonates with unilateral proptosis that progresses rapidly, threatening vision through optic nerve compromise or exposure keratopathy. Globe conservation...

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Conservative Management of Thyroid Eye Disease

By Sadaf Humayun Khan, Uzma Malik, Farooq Ahmed, Zahid Kamal Siddiqui, Samavia Munir, Nawaz Rashid

ABSTRACT The aim of the study was to determine the result of conservative management of Graves ophthalmopathy in a multi-disciplinary setting by a team of ophthalmologists and endocrinologists. Twenty-seven patients of thyroid eye disease were included in the study who underwent complete ocular exam...

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An Audit of the Outcomes of Thymic Surgery

By Pralaya Khadka, Bibhusal Thapa, Ranjan Sapkota, Aakriti Sharma, Prakash Sayami

ABSTRACT Most pathology of the thymus gland warrant its surgical removal; and this requires significant expertise and adequate medical set-up. This study aimed to audit the results of thymectomies performed in a specialised tertiary level centre in a resource-poor country. The outcomes of open and m...

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Increased Peripheral TFH Cells and Serum Interleukin-21 in Childhood Mycoplasma Pneumoniae Pneumonia

By Haiyan Xing, Xiaoyan Liu, Aimin Li, Chunxiang Li, Jianyong Wang

ABSTRACT The aim of this study was to investigate the role of TFH cells and interleukin (IL)-21 in the pathogenesis of childhood Mycoplasma pneumoniae pneumonia (MPP). It was a retrospective study carried out at Yantai Yuhuangding Hospital, China from July 2016 to June 2019. It comprised 46 health...

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Adapting the New Normal Teaching Strategies as a Coping Mechanism for Dental Students

By Suresh Kandagal Veerabhadrappa, Seema Yadav

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Ramsay Hunt Syndrome

By Suman Sen

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Malignant Melamona

By Suman Sen, Sheuli Sen

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Is Pakistan doing Enough to Eradicate Rabies by 2030?

By Ayesha Mubashir, Syeda Asfia Hussain

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Mixed Hemangioma Concurrence with Giant Concha Bullosa Arising from the Middle Concha

By Asuman Kilitci, Harun Soyalic, Omer Faruk Elmas

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Special Issue

Special Supplement 1 on COVID-19 | Volume 31 | Year 2021
Outcomes of Conservative Management of Acute Appendicitis during COVID-19 Pandemic

By Muzna Iftikhar, Sajida Shah, Inamullah Shah, Jamil Ahmad Shah, Mahvish Faisal

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Comparison of HRCT Chest and RT-PCR in Diagnosis of COVID-19

By Nadia Hanif, Ghazala Rubi, Nadia Irshad, Saima Ameer, Uzma Habib, Syed Razi Haider Zaidi

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The Effect of Tocilizumab on Inflammatory Markers in Survivors and Non-survivors of Severe COVID-19

By Said Amin, Fawad Rahim, Sher Bahadur, Mohammad Noor, Afsheen Mahmood, Huma Gul

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Has the COVID-19 Pandemic Increased Mortality Among Patients with Cancer Receiving Systemic Anticancer Treatments?

By Ayşe Demirci, Cemil Bilir, Emre Cakir, Burcu Gulbagci, Ilhan Hacibekiroglu, Ceyhun Varim

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Predictors of Mortality in Patients with COVID-19 Infection-associated Acute Kidney Injury

By Aysel Tocoglu, Hamad Dheir, Melike Bektas, Seyyid Bilal Acikgoz, Oguz Karabay, Savas Sipahi

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Serological Screening of Suspected COVID-19 Patients in Pakistan

By Sajid Ali, Anees Muhammad, Tariq Mehar, Najeeb ur Rehman, Nourin Mehmood, Waseem Iqbal

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Effect of Strict Lockdown on Pediatric Surgical Services and Residency Programme during COVID-19 Pandemic

By Naima Zamir, Syed Muhammad Raees Hussain Taqvi, Jamshed Akhtar, Nasir Saleem Saddal, Muhammad Anwar

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Efficacy and Safety of an Aerosol Box for Percutaneous Tracheostomy in Patients with COVID-19 in an Intensive Care Unit

By Mesut Erbas, Burhan Dost

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Clinical Characteristics and Outcomes among Patients with Covid-19 in Different Regions of the World

By Yuanlin Zhou, Huihai Fan

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Acute Morbidity and Mortality Analysis of COVID-19 in Children Receiving Cancer Treatment

By Najma Shaheen, Rabia Muhammed Wali, Haleema Saeed, Irfana Ishaq Sandhu, Maham Qaisar, Romeena Qazi

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Online Medical Education and Examinations during COVID-19: Perspectives of a Teaching Associate

By Syed Mujtaba Baqir, Fatima Mustansir

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Short-term Changes on Follow-up Chest X-rays of Familial Cluster of COVID-19 Cases

By Chun-Xue Wu, Dong-Dong Rong, Yan-Hong An, Yi Shan, Jie Lu

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COVID-19-related Posterior Reversible Encephalopathy Syndrome in an Adult ICU Patient in Ireland

By Shankar Lal, Ehtesham Khan, Dara Diviney, Jubil Thomas, Tidi Hassan, Ian Counihan

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Right to Left Intrapulmonary Shunt in a Case with COVID-19-associated Pneumonia

By Maimoona Siddique, Muhammad Khalid Nawaz, Muhammad Bin Khalid, Aitzaz Rai

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Vitamin D (Cholecalciferol) with Low Dose Vitamin C as a Safe and Effective Therapeutic Modality in an Adult with COVID-19 Pneumonia

By Shahan Waheed, Rana Osama Zahid, Summaiya Tauseeq Khan, Faysal Subhani, Emaduddin Siddiqui

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Recurrence of COVID-19 Documented with RT-PCR

By Rohat Ak, Erdal Yilmaz, Avni Uygar Seyhan, Fatih Doganay

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COVID-19 Presenting with Spontaneous Pneumothorax

By Intisar Ahmed, Hunaina Shahab, Muhammad Arslan Ahmed, Muhammad Sohaib

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Protective Modifications in Ophthalmology Practice during COVID-19 Pandemic: Challenges and Lessons Learned

By Mohammad Idris, Eemaz Nathaniel

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Airway Management for Emergent Surgeries during COVID-19 Pandemic

By Muhammad Zahoor, Ihtisham Ul Haq

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Health Systems Approach to Ensure Quality and Safety Amid COVID-19 Pandemic in Pakistan

By Nousheen Akber Pradhan, Anam Shahil Feroz, Syed Mairajuddin Shah

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A Single-centre Study of COVID-19 Antibody

By Sidra Ghazanfer, Hasan Osman Mahmood

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Association of Blood Groups with the Severity and Outcome of COVID-19 Infection in Children

By Attia Bari, Aimen Ch, Sidra Hareem, Iqbal Bano, Junaid Rashid, Masood Sadiq

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Imaging Patterns of Encephalopathy in Patients with COVID-19

By Kumail Khandwala, Fatima Mubarak, Muhammad Nadeem Ahmad

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Prospective Effects of Covid-19 on Children: Probable Complications and Interventions

By Naeem Aslam Chughtai

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New Insight for Kidney Biopsy Series in Cases with COVID-19-related Acute Kidney Injury

By İlker Kaya

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