5-Year Impact Factor: 0.9
Volume 35, 12 Issues, 2025

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Important Announcement for Trainees

"A companion journal of JCPSP (the official journal of CPSP) has been launched by the name of JCPSP Postgraduate (JCPSP PG). Submissions to JCPSP PG will be open from March 01, 2025"
For more details, Please visit https://jcpsppg.pk/.

Latest Articles
Volume 35 | Issue 3 | March 2025
Why Will Cancer Incidence Go On Increasing Around the World?

By Shahid Pervez


Is Lactate Clearance Useful in Predicting Cardiopulmonary Resuscitation Outcome and 48-Hour Mortality?

By Erdinc Senguldur, Mehmet Cihat Demir, Kudret Selki

ABSTRACT Objective: To investigate the predictive value of lactate clearance (ΔL) in witnessed cardiac arrest patients in the emergency department (ED) at two time points: Cardiopulmonary resuscitation (CPR) outcome and 48-hour mortality. Study Design: Observational study. Place and Duration o...

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Radiological Response Assessment of Intracranial Meningioma after Cyberknife Stereotactic Radiosurgery

By Hania Siddiqui, Shaista Shaukat, Shazia Kadri, Kamran Saeed, Tariq Mehmood

ABSTRACT Objective: To evaluate the impact of stereotactic radiosurgery (SRS) with a cyberknife system on intracranial meningioma in terms of disease control / clinical outcome and radiological assessment according to the site and histological grading. Study Design: Observational study. Place and Du...

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Impact of Growth Hormone Co-Treatment in Patients with Diminished Ovarian Reserve on In-Vitro Fertilisation Outcomes

By Pinar Karacin, Runa Ozelci, Enes Kumcu, Dilek Kaya kaplanoglu, Serdar Dilbaz, Yaprak Ustun

ABSTRACT Objective: To assess the efficacy of growth hormone (GH) co-treatment during controlled ovarian stimulation for in-vitro fertilisation (IVF). Study Design: Descriptive analytical. Place and Duration of the Study: Department of Gynaecology, Etlik Zubeyde Hanim Training and Research Hospit...

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Frequency of Diabetic Retinopathy and Its Association with HbA1c in Children and Adolescents with Type-I Diabetes Mellitus

By Zubair Ahmed Khoso, Moshina Noor Ibrahim, Versha Rani Rai, Maira Riaz, Taj Muhammad Laghari, Israr Ahmed

ABSTRACT Objective: To determine the frequency of diabetic retinopathy and its association with HbA1c in children and adolescents having Type-I Diabetes Mellitus (T1DM). Study Design: Analytical, cross-sectional study. Place and Duration of the Study: Department of Paediatric Endocrinology and Diabe...


The Effect of Different Surgical Techniques of Haemorrhoidectomy on the Occurrence of Postoperative Hypertrophic Anal Papillae

By Jie Xu, Yongzhi Lv, Weiping Chang, Huan Jia

ABSTRACT Objective: To explore the differences in the occurrence of postoperative hypertrophic anal papillae (HAP) using different surgical techniques (Ferguson haemorrhoidectomy or Milligan-Morgan haemorrhoidectomy), and whether the haemorrhoidectomy technique is an independent risk factor of posto...

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Comparison of CURB-65 and qSOFA Combined with Serum Markers and HRCT in Predicting Mortality in AIDS with Pneumocystis jirovecii Pneumonia

By Sitong Wang, Yunlong Xue

ABSTRACT Objective: To evaluate and compare the clinical predictive value of the CURB-65 and qSOFA scores, combined with serum markers and HRCT scores, in assessing mortality risk in Acquired Immunodeficiency Syndrome (AIDS) patients with Pneumocystis jirovecii pneumonia (PJP). Study Design: Descrip...

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Variations and Clinical Implications of Serum Gal-3 and IL-6 in Heart Failure Individuals Complicated with Renal Impairment

By Jianlong Li, Haiming Li, Yichao Zhang, Xing Fan, Qian Wang, Zhe Li

ABSTRACT Objective: To investigate the variations and clinical implications of serum Gal-3 and IL-6 values in individuals with heart failure (HF) complicated with renal impairment. Study Design: Analytical study. Place and Duration of the Study: Department of Nephrology, The Affiliated Hospital of ...


Effectiveness of Distal Sodium Channel Blocks in Managing Cervical Radiculopathy

By Saira Jilani, Maimuna Rashid, Hina Kanwal Shafaat, Syeda Sarah Naqvi, Tariq Mehmood, Syed Aoun Abbas Mehdi

ABSTRACT Objective: To find the effectiveness of distal sodium channel blocks (DSCB) in managing cervical radiculopathy. Study Design: Open-labelled single-group pilot study. Place and Duration of the Study: Pain Clinic of the Armed Forces Institute of Rehabilitation Medicine, Rawalpindi, Pakistan,...


SLC19A1 Gene Polymorphism; Risk Factor for Preeclampsia

By Iram Nasir, Amena Rahim, Muhammad Afzal, Sadaf Ayub, Zahira Bashir, Naila Zakria

ABSTRACT Objective: To determine the genotypic and allelic frequency of SLC19A1 (rs1051296 G>T) polymorphism in pre-eclamptic patients and normal pregnant females, and also the genetic association of SLC19A1 (rs1051296 G>T) polymorphisms with the levels of homocysteine (Hcy) and folate in pre-...

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Comparison of Efficacy of Low-Level Light Therapy and Intense Pulsed Light Therapy in Patients with Dry Eyes

By Anam Hassan, Shagufta Parveen, Murtaza Sameen, Muhammad Aamir Arain, Muhammad Shahid, Teyyeb Azeem Janjua

ABSTRACT Objective: To compare the efficacy of low-level light therapy (LLLT) and intense pulsed light (IPL) therapy in the treatment of patients with dry eyes. Study Design: Quasi-experimental study. Place and Duration of the Study: Department of Ophthalmology, The Armed Forces Institute of Ophthal...

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Serum Wnt10B/β-Catenin in Early Diagnosis, Lymph Node Metastasis, and Prognosis in Cervical Cancer

By Jingyun Wang, Yahong Wu

ABSTRACT Objective: To assess the serum levels of Wnt10B and β-catenin for early diagnosis of the cervical cancer and their association with distant lymph node metastasis and prognosis. Study Design: Observational study. Place and Duration of the Study: Department of Gynaecology, Hunan Provinci...

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Nomogram for Predicting Pathological Complete Response after Neoadjuvant Chemotherapy in Operable Primary Breast Cancer

By Yanli Lv, Weimin Mu, Qingzhong Yang, Huiying Xu, Baochen Jin, Yi Li

ABSTRACT Objective: To establish a predictive model for pathological complete response (pCR) in operable primary breast cancer after neoadjuvant chemotherapy (NAC). Study Design: Observational study. Place and Duration of the Study: Breast Centre, Shunyi District Health Care Hospital for Women and C...

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Correlation Between Rectus Femoris Muscle Cross-Sectional Area and Severity of Acute Exacerbations of Chronic Obstructive Pulmonary Disease

By Wei Wang, Hongju Bao, Feng Zhu, Lingyun Dong, Xiaoyun Hu, Weizhen Song

ABSTRACT Objective: To assess the correlation between rectus femoris muscle cross-sectional area (RFCSA) and the severity of acute exacerbations of chronic obstructive pulmonary disease (ECOPD). Study Design: Observational study. Place and Duration of the Study: Respiratory and Critical Care Medici...


Influential Determinants on Health-Related Quality of Life in Intensive Care Unit Survivors: A Meta-Analysis

By Limei Fan, Yingru Dou, Yu Liu, Yabin Nie, Juan Du, Yunfeng Bao

ABSTRACT This study aimed to identify the factors influencing the health-related quality of life (HRQoL) in ICU survivors. The electronic search period was established until April 2023, using CNKI, Wanfang, VIP, CBM, PubMed, Embase, and Cochrane databases. Meta-analysis of data was performed using R...

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Prognostic Significance of CD4+ Tumour Infiltrating Lymphocytes in Patients with Non-Small Cell Lung Cancer Receiving PD-1/PD-L1 Inhibitors Therapy

By Qi-Ming Zheng, Yuan-Yuan Li, Ye-Peng Wang, Guo-Xiang Li, Zhi-Gang Sun, Min Zhang

ABSTRACT CD4+ tumour infiltrating lymphocytes (TILs) have been found to produce a marked effect in anti-tumour immunity. In the present study, the authors explored the predictive value of CD4+ TILs in patients with non-small cell lung cancer (NSCLC) receiving PD-1/PD-L1 inhibitors therapy....

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A Systematic Review and Meta-Analysis on the Impact of Screen-Time on the Social-Emotional Development of Children Under Five Years

By Areesha Ahmer, Mohammad Raza, Maha Azhar, Abdur Rahman, Jai Kumar Das, Sidra Kaleem Jafri

ABSTRACT Given the rising consumption of electronic media by children under five years of age, it is crucial to study the impact of screen time (ST) on the social-emotional development (SED) of children. Heterogenous past studies have reported emotional and behavioural problems, delayed language and...


Unveiling the Attitudes of Medical Faculty Towards the Integration of Artificial Intelligence in Medical Education

By Khadija Farrukh Warraich

ABSTRACT Objective: To explore the attitude of faculty members towards integration of artificial intelligence (AI) and to accelerate the appropriate adaptation of AI tools in medical education. Study Design: A qualitative case study. Place and Duration of the Study: Department of Medical Education,...


Fistulectomy and Primary Sphincteroplasty for Transsphincteric Fistula

By Ahmet Cihangir Emral, Merter Gulen, Bahadir Ege

ABSTRACT Objective: To evaluate the results of patients treated with fistulectomy and primary sphincteroplasty for uncomplicated perianal fistula. Study Design: Observational study. Place and Duration of the Study: Medicana International Hospital affiliated with Atilim University, Faculty of Medicin...


Stem Cell Mobilisation Failure in Auto HSCT and Its Factors: A Single Centre Experience

By Irsa Hidayat, Mehreen Ali Khan, Munazza Nabi Awan, Awais Siddiq, Sahla Riaz, Qudrat Ullah

ABSTRACT Objective: To determine the mobilisation failure rate and identify its associated factors in this part of the world in order to identify patients at risk of mobilisation failure and to promptly explore alternative treatment. Study Design: A descriptive study. Place and Duration of the Study...


Long-Term Clinical Outcomes of the Transcatheter Aortic Valve System for Aortic Valve Stenosis

By Zijia Wu, Lulan Gao, Lei Chen, Zhihai Lin

ABSTRACT Objective: To evaluate the clinical safety and efficacy of the self-expanding transcatheter aortic valve system in Chinese patients with severe aortic stenosis (AS) during follow-up. Study Design: Observational study. Place and Duration of the Study: Department of Cardiology, Yulin First Pe...

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Prevalence and Patterns of Dermatological Diseases in Lesbian, Gay, Bisexual, Transgender, and Queer Population: A Cross-Sectional Survey

By Saadiya Siddiqui, Faria Altaf, Abrar Ul Haq, Masooma Zafar, Ahmad Waleed Arshad

ABSTRACT Objective: To determine the frequency and types of dermatological conditions including sexually-transmitted infections (STIs) within the lesbian, gay, bisexual, transgender, and queer (LGBTQ) communities. Study Design: A cross-sectional survey. Place and Duration of the Study: Department of...


Burnout Among Pathology Residents in Pakistan

By Helen Mary Robert, Ahson Ahmed Khan, Humaira Tabassum, Shazia Nayyar, Samina Rehan, Quratulain Sareer

ABSTRACT Objective: To determine the frequency of burnout among pathology residents and the drivers contributing to its development at a tertiary care centre. Study Design: Cross-sectional, descriptive study. Place and Duration of the Study: Armed Forces Institute of Pathology, Rawalpindi, and Combi...


Establishing a Newborn Screening Programme: A Success Story from a Low-Resource Setting

By Hafsa Majid, Lena Jafri, Sibtain Ahmed, Khadija Nuzhat Humayun, Salman Kirmani, Aysha Habib Khan

ABSTRACT The purpose of this communication was to assess the clinical effectiveness of a newborn screening (NBS) programme for congenital hypothyroidism (CH) in a tertiary care centre. This cross-sectional study was conducted from January 2019 to December 2023. Thyroid-stimulating hormone (TSH) ...


Oxidative Balance Scores in Adults with Suicidal Ideation: A Nationwide Korean Survey

By Ki Dong Ko, Jaehyuck Lee, In Cheol Hwang, Hong Yup Ahn

ABSTRACT This cross-sectional study investigated the relationship between oxidative balance (OB) scores and suicidal ideation among the Korean adults. Data from 17,753 adults with information on suicidal ideation and OB scores were analysed using four years of the nationwide survey. A stepwise multi...


Relevance of the Declining Trend in Fluoroscopy Use: Addressing a Diagnostic Challenge in Patient Care

By Muhammad Haseeb Malik


The Need for a Multidimensional Approach to Mortality Prediction in COVID-19:
A Critical Review of Recent Findings

By Muhammad Khawar Ul Hassan Gillani, Muhammad Kashan Sajid


Blazing the Trail for Diagnosis of Infectious Diseases: Why Microbial Infection Imaging Should Be a Pressing Priority in Pakistan

By Moiz Ahmed Khan


Osteomyelitis of the Heel Due to Delayed Treatment of a Left Heel Fracture in a 5-Year Girl

By Zhiqi Zhang, Wendong Xie, Xiudong Liu, Chao Zhang


Morgagni's Hernia and Duodenal Stenosis Found to Co-Exist in Children with Down’s Syndrome: A Case Report

By Yixin Zhang, Qian Liu, Ruimin Liu