Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.

The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.

Latest Articles

Volume 35 | Issue 2 | February 2025

Role of PET/CT Imaging Thyroid Cancers

By Maseeh Uz Zaman, Nosheen Fatima

Effects of Esketamine on Haemodynamics and Inflammatory Stress Response in Elderly Patients Undergoing Proximal Femoral Surgery

By Xuandong Jia, Xingzhi Liao, Maitao Zhou

ABSTRACT Objective: To determine the effects of esketamine combined with iliac fascia block on haemodynamics and inflammatory stress response in elderly patients undergoing proximal femoral nail anti-rotation (PFNA) surgery. Study Design: A single-centre randomised controlled trial. Place and Durat...

Association Between -592 C/A Polymorphism of Interleukin–10 Gene and Diabetic Nephropathy in Type 2 Diabetes Mellitus Patients

By Muhammad Anees, Usman Ali Bajwa, Irfan Elahi, Muhammad Raza, Muhammad Shahbaz Pervaiz

ABSTRACT Objective: To establish the association between -592 C/A polymorphism of interleukin (IL)–10 gene and Diabetic Nephropathy (DNP) in Type 2 Diabetes Mellitus (T2DM) patients. Study Design: Comparative observational study. Place and Duration of the Study: Department of Nephrology (in co...

Open or Laparoscopic Hernia Repair? A Comparative Prospective Study in the Turkish Population

By Mehmet Alperen Avci, Can Akgun, Suleyman Polat, Ahmet Burak Ciftci, Omer Faruk Buk, Emin Daldal

ABSTRACT Objective: To investigate the impact of open (Lichtenstein) and laparoscopic techniques (transabdominal preperitoneal procedure (TAPP), and total extraperitoneal procedure (TEP)) for inguinal hernia repair, on quality of life within a heterogeneous patient population, and to compare the fin...

Clinical Utility of Serum Dehydroepiandrosterone Sulfate (DHEA-S) and Serum Anti-Mullerian Hormone (AMH) Levels in Infertile Females

By Rimsha Sehar, Muhammad Younas, Zujaja Hina Haroon, Muhammad Anwar, Muhammad Usman Munir

ABSTRACT Objective: To determine the correlation of serum dehydroepiandrosterone sulphate and anti-mullerian hormone levels with infertility in females. Study Design: Cross-sectional study. Place and Duration of the Study: Department of Chemical Pathology, the Armed Forces Institute of Pathology, Ra...

Clinicohaematological Characteristics, Cytogenetic Profile, and Risk Stratification in Myelodysplastic Syndrome: A Study from Pakistan

By Alia Waheed, Saleem Ahmed Khan, Ayesha Khursheed, Rafia Mahmood, Humayoon Shafique Satti, Hamid Saeed Malik

ABSTRACT Objective: To determine the clinicohaematological characteristics, cytogenetic abnormalities, and risk profiles of treatment-naive Pakistani myelodysplastic syndrome (MDS) patients. Study Design: Descriptive study. Place and Duration of the Study: Department of Haematology, Armed Forces Ins...

Aspartate Aminotransferase-to-Platelet Ratio Index as Predictors of Recompensation in Decompensated Cirrhosis

By Dedong Yin, Juanli Wu, Yuying Wang, Xu Liu

ABSTRACT Objective: To explore the relationship between aspartate aminotransferase-to-platelet ratio index (APRI) level and recompensation in patients with hepatitis B-related decompensated cirrhosis. Study Design: Analytical study. Place and Duration of the Study: The Second Hospital of Shandong Un...

Causes of Academic Stress and Coping Strategies among Undergraduate Medical Students in Pakistan

By Hamza Masood Gondal, Rabbia Afzal, Amina Masood, Muhammad Bilal Moeen-Ud-Din, Arslan Ahmed, Uzma Iqbal

ABSTRACT Objective: To explore the common causes of educational stress and the coping strategies among undergraduate medical students in Pakistan. Study Design: Descriptive, cross-sectional study. Place and Duration of the Study: Fatima Jinnah Medical University, Lahore, Allama Iqbal Medical College...

An Insight to Hyperhomocysteinaemia in CKD Patients of a Tertiary Care Hospital, Karachi

By Nadia Yaqub, Adnan Mustafa Zubairi, Fatima Kanani, Maliha Zubairy, Ayesha Iftikhar

ABSTRACT Objective: To evaluate the frequency and association of hyperhomocysteinaemia (HHcy) in different stages of chronic kidney disease (CKD) patients. Study Design: Cross-sectional, descriptive study. Place and Duration of the Study: Department of Chemical Pathology, Indus Hospital and Health N...

Alkaline Phosphatase: A Prognostic Biomarker in Non-Metastatic Colon Adenocarcinoma Patients - A Single-Centre Study

By Aminuddin Sheikh, Syed Amir Maqbool, Uzma Raza, Mahay Rookh Asif, Fatima Rizvi, Uzma Bukhari

ABSTRACT Objective: To determine the prognostic significance of liver enzymes in colon carcinoma occurrence in country lifestyle and treatment follow-ups and to correlate them with tumour histopathology. Study Design: A cross-sectional study. Place and Duration of the Study: Department of Oncol...

CD9 as a Potential Prognostic Biomarker in Paediatric B-Cell Acute Lymphoblastic Leukaemia

By Fatima Meraj, Neelum Mansoor, Omer Javed, Saba Jamal

ABSTRACT Objective: To evaluate the role of CD9 for predicting ETV6::RUNX1, BCR::ABL1, and KMT2A fusion genes with prognostic significance in B-cell acute lymphoblastic leukaemia (B-ALL). Study Design: An observational study. Place and Duration of the Study: Indus Hospital and Health Network, Karac...

Radiographic Assessment of Craniofacial Morphology and Airway Dimensions of Parents of Cleft Lip and Palate Patients

By Erum Amin, Qurat Ul Ain Tariq, Adnan Babar, Ramsha Nawaz, Zoya Ahsan

ABSTRACT Objective: To assess and compare maternal and paternal craniofacial morphology and airway dimensions of parents of children with unilateral or bilateral cleft lip and palate (CLP). Study Design: A cross-sectional study. Place and Duration of the Study: Department of Orthodontics, the Armed ...

Exploring Metabolomic Drivers of Colorectal and Gastric Cancer: A Mendelian Randomisation Study

By Yiming Wang, Mi Jian, Jinchen Hu

ABSTRACT Objective: To evaluate the causal relationship between 1,400 metabolites and colorectal and gastric cancer. Study Design: Mendelian randomisation study. Place and Duration of the Study: The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China, from July to August 2024...

The Relationship of Serum Vitamin B12 and Ferritin Levels with Disease Severity and Neuropathic Pain in Fibromyalgia Syndrome

By Meral Kirmizi Bingol, Semra Akturk, Raikan Buyukavci, Sezgin Zontul

ABSTRACT Objective: To investigate the relationship of serum vitamin B12 (vB12) and ferritin levels with disease severity and neuropathic pain in fibromyalgia syndrome (FMS). Study Design: Observational study. Place and Duration of the Study: Department of Physical Medicine and Rehabilitation, Facul...

Antimicrobial Efficacy of Nanoparticle-Coated Gutta-Percha: A Systematic Review

By Samira Adnan, Abhishek Lal, Maham Muneeb Lone, Jamshed Ahmed, Isma Sajjad, Huma Shareef, Muhammad Sohail Zafar

ABSTRACT This systematic review aimed to evaluate the use of different nanoparticles for their ability to impart antimicrobial properties to conventionally inert gutta-percha when it is coated with nanoparticles. After registering with PROSPERO (CRD42023420939), the search was conducted using the Pu...

Effectiveness of Cardiac Rehabilitation on Health-Related Quality of Life in Coronary Artery Disease Patients in Low and Middle-Income Countries

By Aliya Hisam, Zia Ul Haq, Zohaib Khan, Sumaira Masood, Jill P. Pell, Patrick Doherty

ABSTRACT This meta-analysis of published studies was conducted to determine the effectiveness of cardiac rehabilitation (CR) in terms of health-related quality of life (HRQoL) in post-coronary artery disease (CAD) patients in low- and middle-income countries (LMICs). Eighteen studies were identified...

Attributes of Digital Leaders in Health Professions Education

By Sana Iqbal, Mashaal Sabqat, Zainab Akbar, Yawar Hayat Khan, Raheela Yasmin

ABSTRACT Objective: This study investigates the essential attributes of effective digital education leaders (DELs) in health professions education (HPE), aiming to refine digital leadership development and advance digital learning environments in healthcare education. Study Design: Qualitative ...

STN and GPi-Deep Brain Stimulation for Primary Cervical Dystonia

By Tian Wei, Zhu Guanyu, Fan Shiying, Meng Fangang, Yang Anchao, Zhang Jianguo

ABSTRACT Objective: To evaluate the safety and efficiency of deep brain stimulation (DBS) in the treatment of primary cervical dystonia (CD) and to compare the difference between the STN (subthalamic nucleus)-DBS and GPi (Globus Pallidus internus)-DBS. Study Design: Experimental study. Place and Dur...

Clinical Efficacy of Ganglioside Combined with Methylprednisolone in the Treatment of Spinal Cord Injury and Its Effect on Inflammatory Response and Oxidative Stress Factors

By Dongliang Ren, Hui Li, Xiangdong Liu, Meihua Wang

ABSTRACT Objective: To determine the clinical efficacy of monosialotetrahexosylganglioside (GM1) combined with methylprednisolone in the treatment of spinal cord injury (SCI). Study Design: An observational study. Place and Duration of the Study: Department of Orthopaedics, Baoding No.1 Central Hosp...

Treatment Outcome of Haematopoietic Stem Cell Transplant in Fanconi Anaemia: Experience from a Low- and Middle-Income Country

By Hashim Khan, Tariq Ghafoor, Tariq Azam Khattak, Nighat Shahbaz, Munazza Nabi Awan, Awais Siddiq

ABSTRACT Objective: To determine the outcome of haematopoietic stem cell transplantation (HSCT) in Fanconi anaemia (FA) patients. Study Design: Retrospective observational study. Place and Duration of the Study: Department of Clinical Haematology, Armed Forces Bone Marrow Transplant Centre, CMH Raw...

Association of HLA-B51/5 in Patients of Behcet’s Disease Referred to a Tertiary Care Hospital in Pakistan

By Mustajab Alam, Usama Bin Khalid, Dawood Ahmad, Muhammad Omair Riaz, Muhammad Hussain, Muhammad Zain Arshad

ABSTRACT Objective: To determine the association of HLA-B51/5 in patients of Behcet’s disease (BD) in local symptomatic patients. Study Design: A cross-sectional study. Place and Duration of the Study: Department of Immunology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan, fr...

Pain Management in a Tertiary Care Setup: Assessing Patient Satisfaction and Pain Relief

By Muhammad Rashid Iqbal, Aijaz Ali, Mudassar Iqbal, Syed Majid Waseem, Moazam Ali
, Muhammad Tahseen Talib

ABSTRACT The aim of this study was to assess patient satisfaction and pain relief before and after interventions for chronic pain in a tertiary care pain clinic. It was a cross-sectional study, carried out in the Anaesthesia, Pain, and Intensive Care Department of the Combined Military Hospital, Raw...

COVID-19 Associated Neuromuscular Disorders - An Electrodiagnostic Perspective

By Muhammad Tawab Khalil, Uzma Akhlaque, Umer Younas, Sana Arshad

ABSTRACT This cross-sectional study aimed to describe electrodiagnostic (Edx) findings of neuromuscular disorders (NMD) associated with COVID-19 infection. Patients with history of COVID-19 infection and neuromuscular symptoms were included. After documenting the demographics, detailed examination ...

Karachi Faces Chikungunya Surge: Urgent Action Needed to Tackle Growing Health Crisis

By Syed Ammar Salman, Rabiya Mahir, Javeria Hameed

Tofersen for Amyotrophic Lateral Sclerosis: A Step Forward or Another False Hope?

By Araj Naveed, Waqas Ahmed Usmani, Mansi Prakashchandra Vandara, Vikash Kumar Karmani

Rare Epithelioid Sarcoma of the Scalp Involving the Left Parietal Bone

By Pengjuan Zhao, Wendong Xie, Guangsu Zhang, Chao Zhang

Role of Deep Brain Stimulation in Treatment-Resistant Depression: A Way Forward

By Umar Nadeem, Tehreem Fatima, Abira Khan

Inverted Total Shoulder Arthroplasty for Traumatic Shoulder Arthritis

By Lin Zeng, Maimaitiyimin Mir Adili, Kan Jiang, Rongxin Sun